TY - GEN A1 - Brandt, Thomas A1 - Glasauer, Stefan A1 - Schneider, Erich T1 - A third eye for the surgeon T2 - Journal of neurology, neurosurgery, and psychiatry Y1 - 2006 U6 - https://doi.org/10.1136/jnnp.2005.073734 SN - 0022-3050 SN - 1468-330X VL - 77 IS - 2 SP - 278 ER - TY - GEN A1 - Schneider, Erich A1 - Glasauer, Stefan A1 - Dieterich, Marianne A1 - Kalla, Roger A1 - Brandt, Thomas T1 - Diagnosis of vestibular imbalance in the blink of an eye T2 - Neurology Y1 - 2004 SN - 0028-3878 SN - 1526-632X VL - 63 IS - 7 SP - 1209 EP - 1216 ER - TY - GEN A1 - Schneider, Erich A1 - Glasauer, Stefan A1 - Brandt, Thomas A1 - Dieterich, Marianne T1 - Nonlinear nystagmus processing causes torsional vor nonlinearity T2 - Annals of the New York Academy of Sciences Y1 - 2003 SN - 1749-6632 VL - 1004 SP - 500 EP - 505 ER - TY - GEN A1 - Strupp, Michael A1 - Glasauer, Stefan A1 - Jahn, Klaus A1 - Schneider, Erich A1 - Krafczyk, Siegbert A1 - Brandt, Thomas T1 - Eye movements and balance T2 - Annals of the New York Academy of Sciences Y1 - 2003 SN - 1749-6632 VL - 1004 SP - 352 EP - 358 ER - TY - GEN A1 - Heuser, Fabian A1 - Schulz, Christian A1 - Sağlam, Murat A1 - Ramaioli, Cecilia A1 - Heuberger, Maria A1 - Wagner, Klaus J. A1 - Jahn, Klaus A1 - Schneider, Erich A1 - Brandt, Thomas A1 - Glasauer, Stefan A1 - Lehnen, Nadine T1 - Preventing opioid-induced nausea and vomiting: Rest your head and close your eyes? T2 - PloS one Y1 - 2017 U6 - https://doi.org/10.1371/journal.pone.0173925 SN - 1932-6203 VL - 12 IS - 3 SP - e0173925 ER - TY - GEN A1 - Glasauer, Stefan A1 - Dieterich, Marianne A1 - Brandt, Thomas T1 - Neuronal network-based mathematical modeling of perceived verticality in acute unilateral vestibular lesions: from nerve to thalamus and cortex T2 - Journal of Neurology Y1 - 2018 U6 - https://doi.org/10.1007/s00415-018-8909-5 SN - 1432-1459 SN - 0340-5354 VL - 265 IS - Supplement 1 SP - 112 ER - TY - GEN A1 - Dieterich, Marianne A1 - Glasauer, Stefan A1 - Brandt, Thomas T1 - Why acute unilateral vestibular midbrain lesions rarely manifest with rotational vertigo: a clinical and modelling approach to head direction cell function. T2 - Journal of Neurology Y1 - 2018 U6 - https://doi.org/10.1007/s00415-018-8828-5 SN - 0340-5354 SN - 1432-1459 VL - 265 IS - 5 SP - 1184 EP - 1198 ER - TY - GEN A1 - Glasauer, Stefan A1 - Dieterich, Marianne A1 - Brandt, Thomas T1 - Computational neurology of gravity perception involving semicircular canal dysfunction in unilateral vestibular lesions T2 - Progress in Brain Research N2 - Unilateral peripheral vestibular lesions not only lead to vertigo, nystagmus and imbalance, but also to a bias in the perception of verticality, which can be measured as tilt of the subjective visual vertical (SVV). Previously, this tilt has been assumed to be caused by a residual otolith bias, for example, because unequal numbers of active haircells on both sides of the utricular striola might result in an imbalance of the firing rates of central otolith neurons. Here we propose that a tilt of the subjective visual vertical might as well be caused by a vertical semicircular canal bias in the roll axis after unilateral peripheral lesions. The canal bias, acting similar to angular velocity stimuli, influences the SVV via the central gravity estimator, which under normal circumstances resolves a perceptual tilt-translation ambiguity. To illustrate our hypothesis, we compare model predictions to data on SVV measurements in patients with unilateral vestibular lesions while being tilted or being rotated eccentrically. We further embed the model of peripheral processing in a neural network that implements the idiotropic bias and represents the direction of gravity as population code in a three dimensional spherical topography. Y1 - 2019 U6 - https://doi.org/10.1016/bs.pbr.2019.04.010 SN - 1875-7855 SN - 0079-6123 VL - 248 SP - 303 EP - 317 ER - TY - GEN A1 - Schöberl, Florian A1 - Pradhan, Cauchy A1 - Irving, Stephanie A1 - Buerger, Katharina A1 - Xiong, Guoming A1 - Kugler, Günter A1 - Kohlbecher, Stefan A1 - Engmann, Julia A1 - Werner, Philipp A1 - Brendel, Matthias A1 - Schneider, Erich A1 - Perneczky, Robert A1 - Jahn, Klaus A1 - Fougère, Christian la A1 - Bartenstein, Peter A1 - Brandt, Thomas A1 - Dietrich, Marianne A1 - Zwergal, Andreas T1 - Real-space navigation testing differentiates between amyloid-positive and -negative aMCI T2 - Neurology : official journal of the American Academy of Neurology Y1 - 2020 UR - https://n.neurology.org/content/94/8/e861 U6 - https://doi.org/10.1212/WNL.0000000000008758 SN - 1526-632X VL - 94 IS - 8 SP - e861 EP - e873 ER - TY - GEN A1 - Schöberl, Florian A1 - Irving, Stephanie A1 - Pradhan, Cauchy A1 - Bardins, Stanislav A1 - Trapp, Christoph A1 - Schneider, Erich A1 - Kugler, Günter A1 - Bartenstein, Peter A1 - Dietrich, Marianne A1 - Brandt, Thomas A1 - Zwergal, Andreas T1 - Prolonged allocentric navigation deficits indicate hippocampal damage in TGA T2 - Neurology : official journal of the American Academy of Neurology N2 - Objective To investigate long-term recovery of allocentric and egocentric spatial orientation as a sensitive marker for hippocampal and extrahippocampal network function in transient global amnesia (TGA). Methods A group of 18 patients with TGA performed an established real-space navigation paradigm, requiring allo- and egocentric spatial orientation abilities, 3 days (postacute stage) and 3 months (follow-up) after symptom onset. Visual exploration behavior and navigation strategy were documented by a gaze-controlled, head-fixed camera. Allo- and egocentric spatial orientation performance was compared to that of 12 age-matched healthy controls. Navigation-induced brain activations were measured using [18F]-fluorodeoxyglucose-PET in a subgroup of 8 patients in the postacute stage and compared to those of the controls. Results In the postacute stage, the patients navigated worse and had higher error rates than controls in allocentric (p = 0.002), but not in egocentric, route planning (p = 0.30), despite complete recovery of verbal (p = 0.58) and figural memory (p = 0.11). Until follow-up, allocentric navigation deficits improved, but higher error rates and reduced use of shortcuts persisted (p < 0.0001). Patients still exhibited relatively more fixations of unique landmarks during follow-up (p = 0.05). PET measurements during the postacute stage showed increased navigation-induced brain activations in the right hippocampus, bilateral retrosplenial, parietal, and mesiofrontal cortices, and cerebellar dentate nucleus in patients compared to controls (p < 0.005). Conclusions Patients with TGA show selective and prolonged deficits of allocentric spatial orientation. Activations in right hippocampal and extrahippocampal hubs of the cerebral navigation network functionally substitute for the deficit in creating and updating the internal cognitive map in TGA. Y1 - 2019 UR - https://n.neurology.org/content/92/3/e234/tab-article-info U6 - https://doi.org/10.1212/WNL.0000000000006779 SN - 0028-3878 SN - 1526-632X VL - 92 IS - 3 SP - e234 EP - e243 ER - TY - GEN A1 - Spiegel, Rainer A1 - Claassen, Jens A1 - Teufel, Julian A1 - Bardins, Stanislav A1 - Schneider, Erich A1 - Lehrer, Nicole A1 - Jahn, Klaus A1 - Anciaes da Silva, Fábio A1 - Hahn, Ales A1 - Farahmand, Parvis A1 - Brandt, Thomas A1 - Strupp, Michael A1 - Kalla, Roger T1 - Resting in darkness improves downbeat nystagmus: evidence from an observational study T2 - Annals of the New York Academy of Sciences N2 - Resting in an upright position during daytime decreases downbeat nystagmus (DBN). When measured in brightness only, that is, without intermitting exposure to darkness, it does not make a significant difference whether patients have previously rested in brightness or in darkness. In real-world scenarios, people are often exposed to brightness and darkness intermittently. The aim of this study was to analyze whether resting in brightness or resting in darkness was associated with a lower post-resting DBN after intermitting exposures to brightness and darkness. Eight patients were recorded with three-dimensional video-oculography in brightness and darkness conditions, each following two 2-h resting intervals under either brightness or darkness resting conditions. The dependent variable was DBN intensity, measured in mean slow phase velocity. A repeated measures ANOVA with the factors measurement condition (brightness vs. darkness), resting condition (brightness vs. darkness), and time (after first vs. second resting interval) showed a significant effect for the factor resting condition, where previous resting in darkness was associated with a significantly lower DBN relative to previous resting in brightness (P < 0.01). The clinical relevance is to advise patients with DBN to rest in darkness. KW - downbeat nystagmus KW - symptom relief KW - resting KW - oscillopsia KW - video-oculographic measurement (VOG) Y1 - 2016 U6 - https://doi.org/10.1111/nyas.13172 SN - 1749-6632 SN - 0077-8923 VL - 1375 IS - 1 SP - 66 EP - 73 ER - TY - GEN A1 - Hall, Braeden A1 - Schmidt, Kathleen A1 - Wagge, Jordan A1 - Lewis, Savannah C. A1 - Weissgerber, Sophia C. A1 - Kiunke, Felix A1 - Pfuhl, Gerit A1 - Stieger, Stefan A1 - Tran, Ulrich S. A1 - Barzykowski, Krystian A1 - Bogatyreva, Natalia A1 - Kowal, Marta A1 - Massar, KarlIJn A1 - Pernerstofer, Felizitas A1 - Sorokowski, Piotr A1 - Voracek, Martin A1 - Chartier, Christopher R. A1 - Brandt, Mark J. A1 - Grahe, Jon E. A1 - Özdoğru, Asil A. A1 - Andreychik, Michael R. A1 - Chen, Sau-Chin A1 - Evans, Thomas R. A1 - Hautekiet, Caro A1 - IJzerman, Hans A1 - Kačmár, Pavol A1 - Krafnick, Anthony J. A1 - Musser, Erica D. A1 - Vergauwe, Evie A1 - Werner, Kaitlyn M. A1 - Aczel, Balazs A1 - Arriaga, Patrícia A1 - Batres, Carlota A1 - Beaudry, Jennifer L. A1 - Cova, Florian A1 - Ďurbisová, Simona A1 - Cramblet Alvarez, Leslie D. A1 - Feldman, Gilad A1 - Godbersen, Hendrik A1 - Gottfried, Jaroslav A1 - Haeffel, Gerald J. A1 - Hartanto, Andree A1 - Isloi, Chris A1 - McFall, Joseph P. A1 - Milyavskaya, Marina A1 - Moreau, David A1 - Nosáľová, Ester A1 - Papaioannou, Kostas A1 - Ruiz-Fernandez, Susana A1 - Schrötter, Jana A1 - Storage, Daniel A1 - Vezirian, Kevin A1 - Volz, Leonhard A1 - Weisberg, Yanna J. A1 - Xiao, Qinyu A1 - Awlia, Dana A1 - Branit, Hannah W. A1 - Dunn, Megan R. A1 - Groyecka-Bernard, Agata A1 - Haneda, Ricky A1 - Kielinska, Julita A1 - Kolle, Caroline A1 - Lubomski, Paweł A1 - Miller, Alexys M. A1 - Mækelæ, Martin J. A1 - Pantazi, Mytro A1 - Ribeiro, Rafael R. A1 - Ross, Robert M. A1 - Sorokowska, Agnieszka A1 - Aberson, Christopher L. A1 - Vassiliou, Xanthippi Alexi A1 - Baker, Bradley J. A1 - Bognar, Miklos A1 - Cong, Chin Wen A1 - Danvers, Alex F. A1 - Davis, William E. A1 - Dranseika, Vilius A1 - Dumbravă, Andrei A1 - Farmer, Harry A1 - Field, Andy P. A1 - Forscher, Patrick S. A1 - Graton, Aurélien A1 - Hajdu, Nandor A1 - Howlett, Peter A. A1 - Kabut, Radosław A1 - Larsen, Emmett M. A1 - Lee, Sean T. H. A1 - Legate, Nicole A1 - Levitan, Carmel A. A1 - Levy, Neil A1 - Lu, Jackson G. A1 - Misiak, Michał A1 - Morariu, Roxana E. A1 - Novak, Jennifer A1 - Pronizius, Ekaterina A1 - Prusova, Irina A1 - Rathnayake, Athulya S. A1 - Romanova, Marina O. A1 - Röer, Jan P. A1 - Sampaio, Waldir M. A1 - Schild, Christoph A1 - Schulte-Mecklenbeck, Michael A1 - Stephen, Ian D. A1 - Szecsi, Peter A1 - Takacs, Elizabeth A1 - Teeter, Julia N. A1 - Thiele-Evans, Elian H. A1 - Valeiro-Paterlini, Julia A1 - Vilares, Iris A1 - Villafana, Louise A1 - Wang, Ke A1 - Wu, Raymond A1 - Álvarez-Solas, Sara A1 - Moshontz, Hannah A1 - Buchanan, Erin M. T1 - Registered Replication Report: A Large Multilab Cross-Cultural Conceptual Replication of Turri et al. (2015) T2 - Advances in Methods and Practices in Psychological Science Y1 - 2024 U6 - https://doi.org/10.1177/25152459241267902 SN - 2515-2459 VL - 7 IS - 4 SP - 1 EP - 38 PB - SAGE Publications ER -