TY - GEN A1 - Taoka, Noriyuki A1 - Asano, Takanori A1 - Yamaha, Takashi A1 - Terashima, Tatsuya A1 - Nakatsuka, Osamu A1 - Costina, Ioan A1 - Zaumseil, Peter A1 - Capellini, Giovanni A1 - Zaima, Shigeaki A1 - Schroeder, Thomas T1 - Non-uniform depth distributions of Sn concentration induced by Sn migration and desorption during GeSnSi layer formation T2 - Applied Physics Letters Y1 - 2015 U6 - https://doi.org/10.1063/1.4908121 SN - 1077-3118 VL - 106 SP - 061107-1 EP - 061107-5 ER - TY - GEN A1 - Chahine, Gilbert A. A1 - Zöllner, Marvin Hartwig A1 - Richard, Marie-Ingrid A1 - Subhajit, G. A1 - Zaumseil, Peter A1 - Capellini, Giovanni A1 - Schroeder, Thomas A1 - Schülli, Tobias U. T1 - Strain and Lattice Orientation Distribution in SiN/Ge CMOS Compatible Light Emitters Microstructures by Quick X-ray Nano-diffraction Microscopy T2 - Applied Physics Letters Y1 - 2015 U6 - https://doi.org/10.1063/1.4909529 SN - 1077-3118 VL - 106 SP - 071902-1 EP - 071902-4 ER - TY - GEN A1 - Wirths, S. A1 - Troitsch, R. A1 - Mussler, G. A1 - Stoica, T. A1 - Hartmann, J.-M. A1 - Zaumseil, Peter A1 - Schroeder, Thomas A1 - Mantl, Siegfried A1 - Buca, Dan T1 - Ternary and Quaternary Ni(Si)GeSn Contact Formation for highly strained Ge p- and n-MOSFETs T2 - Semiconductor Science and Technology Y1 - 2015 U6 - https://doi.org/10.1088/0268-1242/30/5/055003 SN - 0268-1242 VL - 30 IS - 5 SP - 055003 ER - TY - GEN A1 - Zaumseil, Peter A1 - Yamamoto, Yuji A1 - Schubert, M. A1 - Capellini, Giovanni A1 - Skibitzki, Oliver A1 - Zöllner, Marvin Hartwig A1 - Schroeder, Thomas T1 - Tailoring the strain in Si nano-structures for defect-free epitaxial Ge overgrowth T2 - Nanotechnology Y1 - 2015 U6 - https://doi.org/10.1088/0957-4484/26/35/355707 SN - 1361-6528 VL - 26 IS - 35 SP - 355707 ER - TY - CHAP A1 - Hirsch, Florian A1 - Raab, Thomas A1 - Schneider, Anna A1 - Wechler, Klaus-Peter T1 - Late Holocene eolian fossilization of Podzols in Northeastern Germany T2 - European Geosciences Union, General Assembly 2016, Vienna, Austria N2 - The North European lowland has been formed by glacial and periglacial processes in the Late Pleistocene. Multiple reshaping since the Late Glacial considerably changed the landscape up to and including especially historic times. Sediment sequences and (fossilized) soils can improve our understanding of Late Quaternary landscape development, but mapping of buried soils and surfaces is often limited to single outcrops. Ongoing archaeological rescue excavations in the pre-field of the open-cast mine Cottbus-Nord (northeastern Germany) with dense excavation trenches in an about 10 ha dune and drift sand area reveal multilayered sediment sequences with fossilized soils and sediments from the Late Pleistocene to the Late Holocene. Archaeological findings ranging from Mesolithic flint stones to an about 200 year old ceramics in eolian sediments covering plow horizons and wheel tracks suggest that eolian relocation of sandy material was intensive about 200 years ago. Still unpublished OSL dating underline the intense eolian activity. Recent studies showed that between the 15Th to the 19Th century an iron smelter 5 km to the west of our study site was supplied with charcoal, which was produced in a forest 5 km east to our study site. Our current findings about Late Holocene eolian activity raise the question if this eolian reshaping of the landscape is connected with the operation of the iron smelter either directly by transport or bog iron ore winning or indirectly by population pressure caused by the prospering iron smelter. Our ongoing research indicates, that already for historic land-use off-site effects causing further landscape changes have to be considered. Y1 - 2016 N1 - EGU2016-5754-1 PB - European Geophysical Society CY - Katlenburg-Lindau ER - TY - GEN A1 - Wilczek, Sebastian A1 - Trieschmann, Jan A1 - Schulze, Julian A1 - Schüngel, Edmund A1 - Brinkmann, Ralf Peter A1 - Derzsi, Aranka A1 - Korolov, Ihor A1 - Donkó, Zoltán A1 - Mussenbrock, Thomas T1 - The Effect of the Driving Frequency on the Confinement of Beam Electrons and Plasma Density in Low Pressure Capacitive Discharges T2 - Plasma Sources Science and Technology Y1 - 2015 U6 - https://doi.org/10.1088/0963-0252/24/2/024002 SN - 0963-0252 SN - 1361-6595 VL - 24 IS - 2 SP - 024002 ER - TY - GEN A1 - Gallian, Sara A1 - Trieschmann, Jan A1 - Mussenbrock, Thomas A1 - Brinkmann, Ralf Peter A1 - Hitchon, William N. G. T1 - Analytic model of the Energy Distribution Function for Highly Energetic Electrons in Technological Plasmas T2 - Journal of Applied Physics Y1 - 2015 U6 - https://doi.org/10.1063/1.4905943 SN - 1089-7550 SN - 0021-8979 VL - 117 IS - 2 SP - 023305 ER - TY - PAT A1 - Heil, Brian George A1 - Czarnetzki, Uwe A1 - Brinkmann, Ralf Peter A1 - Mussenbrock, Thomas T1 - Method for Controlling Ion Energy in Radio Frequency Plasma Y1 - 2013 ER - TY - GEN A1 - Kemaneci, Efe A1 - Booth, Jean-Paul A1 - Chabert, Pascal A1 - Dijk, Jan van A1 - Mussenbrock, Thomas A1 - Brinkmann, Ralf Peter T1 - A Computational Analysis of the Vibrational Quanta of Molecular Oxygen in Low Pressure Stationary and Transient Radio-Frequency Oxygen Plasmas T2 - Plasma Sources Science and Technology Y1 - 2016 U6 - https://doi.org/10.1088/0963-0252/25/2/025025 SN - 1361-6595 SN - 0963-0252 VL - 25 IS - 2 SP - 025025 ER - TY - CHAP A1 - Wilczek, Sebastian A1 - Trieschmann, Jan A1 - Schulze, Julian A1 - Schüngel, Edmund A1 - Brinkmann, Ralf Peter A1 - Derzsi, Aranka A1 - Korolov, Ihor A1 - Donkó, Zoltán A1 - Mussenbrock, Thomas T1 - Confinement of highly energetic electron beams in low pressure capacitive discharges T2 - Plasma Sciences (ICOPS), 2015 IEEE International Conference on, May 24-28, 2015, Antalya, Turkey Y1 - 2015 SN - 978-1-4799-6974-6 U6 - https://doi.org/10.1109/PLASMA.2015.7179545 PB - IEEE CY - Piscataway, NJ ER - TY - CHAP A1 - Gallian, Sara A1 - Trieschmann, Jan A1 - Mussenbrock, Thomas A1 - Hitchon, William N. G. A1 - Brinkmann, Ralf Peter T1 - Analytic model of the energy distribution for energetic electrons in HiPIMS T2 - 2015 IEEE International Conference on Plasma Sciences (ICOPS), 24 - 28 May 2015, Belek, Antalya, Turkey Y1 - 2015 SN - 978-1-4799-6974-6 U6 - https://doi.org/10.1109/PLASMA.2015.7179892 PB - IEEE CY - Piscataway, NJ ER - TY - CHAP A1 - Szeremley, Daniel A1 - Mussenbrock, Thomas A1 - Brinkmann, Ralf Peter A1 - Zimmermanns, Marc A1 - Rolfes, Ilona A1 - Eremin, Denis T1 - Comparison of a numerical and analytical model for the simulation of the mode propagation in a microwave driven plasma discharges T2 - Plasma Sciences (ICOPS), 2015 IEEE International Conference on, May 24-28, 2015, Antalya, Turkey Y1 - 2015 SN - 978-1-4799-6974-6 U6 - https://doi.org/10.1109/PLASMA.2015.7179679 PB - IEEE CY - Piscataway, NJ ER - TY - CHAP A1 - Wilczek, Sebastian A1 - Trieschmann, Jan A1 - Brinkmann, Ralf Peter A1 - Mussenbrock, Thomas A1 - Schulze, Julian A1 - Schüngel, Edmund A1 - Derzsi, Aranka A1 - Korolov, Ihor A1 - Hartmann, Paul A1 - Donkó, Zoltán T1 - Hysteresis effects and confinement of beam electrons in capacitive discharges T2 - 2016 IEEE International Conference on Plasma Science (ICOPS), Banff, Canada, June 19-23, 2016 Y1 - 2016 SN - 978-1-4673-9601-1 U6 - https://doi.org/10.1109/PLASMA.2016.7534342 PB - IEEE CY - Piscataway, NJ ER - TY - CHAP A1 - Wilczek, Sebastian A1 - Brinkmann, Ralf Peter A1 - Mussenbrock, Thomas T1 - Nonlinear electron resonance heating in asymmetric capacitive discharges T2 - 2016 IEEE International Conference on Plasma Science (ICOPS), Banff, Canada, June 19-23, 2016 Y1 - 2016 SN - 978-1-4673-9601-1 U6 - https://doi.org/10.1109/PLASMA.2016.7534107 PB - IEEE CY - Piscataway, NJ ER - TY - GEN A1 - Tarnawska, Lidia Lupina A1 - Zöllner, Marvin Hartwig A1 - Niermann, T. A1 - Dietrich, Burkhart A1 - Capellini, Giovanni A1 - Thapa, Sarad A1 - Häberlen, Maik A1 - Lehmann, M. A1 - Storck, Peter A1 - Schröder, Thomas T1 - Zero Lattice Mismatch and Truly Single Crystalline ScN Buffer Layers for GaN Growth on Silicon T2 - Applied Physics Letters Y1 - 2015 U6 - https://doi.org/10.1063/1.4935856 SN - 1077-3118 SN - 0003-6951 VL - 107 IS - 20 SP - 201907 ER - TY - GEN A1 - Niu, Gang A1 - Capellini, Giovanni A1 - Lupina, Grzegorz A1 - Niermann, Tore A1 - Salvalaglio, Marco A1 - Marzegalli, Anna A1 - Schubert, Markus Andreas A1 - Zaumseil, Peter A1 - Krause, Hans-Michael A1 - Skibitzki, Oliver A1 - Lehmann, Michael A1 - Montalenti, Francesco A1 - Xie, Ya-Hong A1 - Schröder, Thomas T1 - Photodetection in hybrid single layer graphene/fully coherent Ge island nanostructures selectively grown on Si nano-tip patterns T2 - ACS Applied Materials and Interfaces Y1 - 2016 SN - 1944-8252 VL - 8 IS - 3 SP - 2017 EP - 2026 ER - TY - GEN A1 - Zaumseil, Peter A1 - Schubert, Markus Andreas A1 - Yamamoto, Yuji A1 - Skibitzki, Oliver A1 - Capellini, Giovanni A1 - Schröder, Thomas T1 - Misfit dislocation-free epitaxial growth of SiGe on compliant nanostructured Silicon T2 - Solid State Phenomena Y1 - 2016 U6 - https://doi.org/10.4028/www.scientific.net/SSP.242.402 SN - 1662-9779 SN - 0377-6883 VL - 242 SP - 402 EP - 407 ER - TY - GEN A1 - Taoka, Noriyuki A1 - Capellini, Giovanni A1 - Driesch, Nils von den A1 - Buca, Dan A1 - Zaumseil, Peter A1 - Schubert, Markus Andreas A1 - Klesse, Wolfgang Matthias A1 - Montanari, Michele A1 - Schröder, Thomas T1 - Sn Migration Control at High Temperature Due to High Deposition Speed for Forming High Quality GeSn Layer T2 - Applied Physics Express Y1 - 2016 U6 - https://doi.org/10.7567/APEX.9.031201 SN - 1882-0786 SN - 1882-0778 VL - 9 IS - 3 SP - 031201 ER - TY - GEN A1 - Niu, Gang A1 - Capellini, Giovanni A1 - Schubert, Markus Andreas A1 - Niermann, Tore A1 - Zaumseil, Peter A1 - Katzer, Jens A1 - Krause, Hans-Michael A1 - Skibitzki, Oliver A1 - Lehmann, Michael A1 - Xie, Ya-Hong A1 - Känel, Hans von A1 - Schröder, Thomas T1 - Dislocation-free Ge nano-crystals via pattern dependent selective Ge heteroepitaxy on Si nano-tip wafers T2 - Scientific Reports Y1 - 2016 U6 - https://doi.org/10.1038/srep22709 SN - 2045-2322 VL - 6 SP - 22709 ER - TY - GEN A1 - Engelhard, M. A1 - Klemp, C. A1 - Behringer, M. A1 - Rudolph, A. A1 - Skibitzki, Oliver A1 - Zaumseil, Peter A1 - Schröder, Thomas T1 - Characterization of reclaimed GaAs substrates and investigation of reuse for thin film InGaAlP LED epitaxial growth T2 - Journal of Applied Physics Y1 - 2016 U6 - https://doi.org/10.1063/1.4955333 SN - 1089-7550 SN - 0021-8979 VL - 120 IS - 4 SP - 045301 ER - TY - GEN A1 - Niu, Gang A1 - Capellini, Giovanni A1 - Hatami, Fariba A1 - Bartolomeo, Antonio di A1 - Niermann, Tore A1 - Hameed, Hussein Emad A1 - Schubert, Markus Andreas A1 - Krause, Hans-Michael A1 - Zaumseil, Peter A1 - Skibitzki, Oliver A1 - Masselink, William T. A1 - Lehmann, Michael A1 - Xie, Ya-Hong A1 - Schröder, Thomas T1 - Selective Epitaxy of InP on Si and Rectification in Graphene/InP/Si Hybrid Structure T2 - ACS Applied Materials and Interfaces Y1 - 2016 U6 - https://doi.org/10.1021/acsami.6b09592 SN - 1944-8244 SN - 1944-8252 VL - 8 IS - 40 SP - 26948 EP - 26955 ER - TY - GEN A1 - Skibitzki, Oliver A1 - Capellini, Giovanni A1 - Yamamoto, Yuji A1 - Zaumseil, Peter A1 - Schubert, Markus Andreas A1 - Schröder, Thomas A1 - Ballabio, Andrea A1 - Bergamaschini, Roberto A1 - Salvalaglio, Marco A1 - Miglio, Leo A1 - Montalenti, Francesco T1 - RP-CVD growth of isolated Ge crystals and suspended layers on micrometric Si pillars T2 - ACS Applied Materials and Interfaces Y1 - 2016 U6 - https://doi.org/10.1021/acsami.6b07694 SN - 1944-8244 SN - 1944-8252 VL - 8 IS - 39 SP - 26374 EP - 26380 ER - TY - GEN A1 - Sana, Prabha A1 - Tetzner, Henriette A1 - Dabrowski, Jarek Marek A1 - Tarnawska, Lidia Lupina A1 - Costina, Ioan A1 - Thapa, Sarad A1 - Storck, Peter A1 - Schröder, Thomas A1 - Zöllner, Marvin Hartwig T1 - Growth of ScN(111) on Sc₂O₃ (111) for GaN integration on Si(111): Experiment and ab initio calculations T2 - Journal of Applied Physics Y1 - 2016 U6 - https://doi.org/10.1063/1.4963826 SN - 1089-7550 SN - 0021-8979 VL - 120 SP - 135103 ER - TY - GEN A1 - Schlykow, Viktoria A1 - Klesse, Wolfgang Matthias A1 - Niu, Gang A1 - Taoka, Noriyuki A1 - Yamamoto, Yuji A1 - Skibitzki, Oliver A1 - Barget, M. R. A1 - Zaumseil, Peter A1 - Känel, Hans von A1 - Schubert, Markus Andreas A1 - Capellini, Giovanni A1 - Schroeder, Thomas T1 - Selective growth of fully relaxed GeSn nano-islands by nanoheteroepitaxy on patterned Si(001) T2 - Applied Physics Letters Y1 - 2016 U6 - https://doi.org/10.1063/1.4967500 SN - 1077-3118 VL - 109 IS - 20 SP - 202102 ER - TY - CHAP A1 - Hinze, Thomas A1 - Grützmann, Konrad A1 - Höckner, Benny A1 - Sauer, Peter A1 - Hayat, Sikander ED - Gheorghe, Marian ED - Rozenberg, Grzegorz ED - Salomaa, Arto ED - Sosík, Petr ED - Zandron, Claudio T1 - Categorised Counting Mediated by Blotting Membrane Systems for Particle-Based Data Mining and Numerical Algorithms T2 - Membrane computing, 15th International Conference, CMC 2014 Prague, Czech Republic, August 20–22, 2014 Y1 - 2014 SN - 978-3-319-14369-9 SP - 241 EP - 257 PB - Springer CY - Cham [u.a.] ER - TY - CHAP A1 - Hinze, Thomas A1 - Kirkici, Korcan A1 - Sauer, Patricia A1 - Sauer, Peter A1 - Behre, Jörn ED - Rozenberg, Grzegorz ED - Salomaa, Arto ED - Sempere, José M. ED - Zandron, Claudio T1 - Membrane Computing Meets Temperature: A Thermoreceptor Model as Molecular Slide Rule with Evolutionary Potential T2 - Membrane Computing, 16th International Conference, CMC 2015, Valencia, Spain, August 17-21, 2015, Y1 - 2015 SN - 978-3-319-28474-3 SP - 215 EP - 235 PB - Springer Verlag CY - Cham [u.a.] ER - TY - CHAP A1 - Schneider, Anna A1 - Hirsch, Florian A1 - Wechler, Klaus-Peter A1 - Raab, Alexandra A1 - Raab, Thomas T1 - Mapping a paleosurface and archaeological site location in an inland dune area in Brandenburg, Germany T2 - European Geosciences Union, General Assembly 2017, Vienna, Austria N2 - Mapping and visualizing the position of archaeological remains in the surface relief provides important basic information for archaeological survey design and interpretation. Geomorphological processes in (pre)history can have resulted in a modification of the local relief around archaeological sites, especially in areas that are prone to sediment erosion and relocation, so that models of past surfaces are necessary for a correct interpretation of archaeological survey results. In this study, we combined terrestrial survey and remote sensing methods to reconstruct the palaeorelief around two archaeological excavation sites in an inland dune area in southern Brandenburg, Germany. Remains from two Mesolithic hunter-gatherer camps were documented in archaeological excavations and found to be associated with a buried soil horizon. To gather information on the relief of the buried soil surface, we used a combination of sedimentological and pedological profile description of archaeological survey trenches and geophysical prospection with Ground-Penetrating Radar; supplemented by microdrone photography and photogrammetry, GPS surveys and analysis of LIDAR-based elevation models. A digital elevation model of the buried surface was created by combining point data from these sources. The buried surface morphology and the position of the archeological remains within the reconstructed landscape were analyzed in GIS. The comparison of the generated paleosurface model with the recent surface elevation model shows that sand remobilization resulted in a considerable reshaping of the relief. Analysis of the buried surface model further shows that the relief position of the two archaeological sites in the study area was considerably more prominent in relation to the corresponding buried soil surface than in relation to the recent surface morphology. Results affirm the importance of considering Holocene relief modifications in archaeological surveys. Y1 - 2017 UR - http://meetingorganizer.copernicus.org/EGU2017/EGU2017-6066-1.pdf N1 - EGU2017-6066-1 PB - European Geophysical Society CY - Katlenburg-Lindau ER - TY - CHAP A1 - Schneider, Anna A1 - Hirsch, Florian A1 - Wechler, Klaus-Peter A1 - Raab, Alexandra A1 - Raab, Thomas ED - Schwab, Markus ED - Błaszkiewicz, Mirek ED - Raab, Thomas ED - Wilmking, Martin ED - Brauer, Achim T1 - Mapping a palaeosurface and archaeological site location in an anthropogenic drift sand area T2 - ICLEA Final Symposium 2017, Human Impact and Landscape Evolution in the Southern Baltic Lowlands, Abstract Volume & Excursion Guide Y1 - 2017 UR - http://gfzpublic.gfz-potsdam.de/pubman/item/escidoc:2215927 U6 - https://doi.org/10.2312/GFZ.b103-17037 SP - 152 EP - 154 ER - TY - CHAP A1 - Klimczak, Peter A1 - Zoglauer, Thomas ED - Klimczak, Peter ED - Zoglauer, Thomas T1 - Einleitung - Was heißt Logik anwenden? T2 - Logik in den Wissenschaften KW - Logik KW - formale Logik KW - Wissenschaftstheorie KW - Methodologie KW - Methoden KW - Tool KW - Heuristik Y1 - 2017 SN - 978-3-95743-108-0 SP - 7 EP - 17 PB - Mentis Verlag CY - Münster ER - TY - CHAP A1 - Beirow, Bernd A1 - Kühhorn, Arnold A1 - Figaschewsky, Felix A1 - Hönisch, Peter A1 - Giersch, Thomas A1 - Schrape, Sven T1 - Model Update and Validation of a Mistuned High Pressure Compressor Blisk T2 - Proceedings of ISABE 2017, ISABE-2017-22568, Manchester, September 3.-8., 2017 Y1 - 2017 UR - https://isabe2017.org/ PB - ISABE ER - TY - GEN A1 - Daksha, Manaswi A1 - Derzsi, Aranka A1 - Wilczek, Sebastian A1 - Trieschmann, Jan A1 - Mussenbrock, Thomas A1 - Awakowicz, Peter A1 - Donkó, Zoltán A1 - Schulze, Julian T1 - The Effect of Realistic Heavy Particle Induced Secondary Electron Emission Coefficients on the Electron Power Absorption Dynamics in Single- and Dual-Frequency CCPs T2 - Plasma Sources Science and Technology Y1 - 2017 U6 - https://doi.org/10.1088/1361-6595/aa7c88 SN - 1361-6595 SN - 0963-0252 VL - 26 IS - 8 SP - 085006 ER - TY - GEN A1 - Eremin, Denis A1 - Brinkmann, Ralf Peter A1 - Mussenbrock, Thomas T1 - Observations of Surface Mode Influence on Plasma Uniformity in PIC/MCC Simulations of Large Capacitive Discharges T2 - Plasma Processes and Polymers Y1 - 2017 U6 - https://doi.org/10.1002/ppap.201600164 SN - 1612-8869 VL - 14 IS - 4-5 ER - TY - GEN A1 - Schmidt, Frederik A1 - Trieschmann, Jan A1 - Brinkmann, Ralf Peter A1 - Mussenbrock, Thomas T1 - Nonlinear interaction of capacitive discharges and power matching networks T2 - Bulletin of the American Physical Society Y1 - 2017 SN - 0003-0503 N1 - 70th Annual Gaseous Electronics Conference, Monday–Friday, November 6–10, 2017, Pittsburgh, Pennsylvania VL - 62 IS - 10 ER - TY - GEN A1 - Kammerer, Sarah A1 - Jahn, Stephan Wenzel A1 - Winter, Elke A1 - Eidenhammer, Sylvia A1 - Rezania, Simin A1 - Regitnig, Peter A1 - Pichler, Martin A1 - Schreibmayer, Wolfgang A1 - Bauernhofer, Thomas T1 - Critical evaluation of KCNJ3 gene product detection in human breast cancer: MRNA in situ hybridisation is superior to immunohistochemistry T2 - Journal of Clinical Pathology N2 - Increased expression levels of KCNJ3 have been correlated with lymph node metastases and poor prognosis in patients with breast cancer, suggesting a prognostic role of KCNJ3. We aimed to establish protocols for the detection of KCNJ3 in formalin-fixed, paraffin-embedded (FFPE) breast cancer tissue. Several antibodies were tested for sensitivity and specificity by western blot, followed by optimisation of the immunohistochemistry (IHC) procedure and establishment of KCNJ3 mRNA in situ hybridisation (ISH). Methods were validated by processing 15 FFPE breast cancer samples for which microarray data were available. Spearman's rank correlation analysis resulted in borderline significant correlation for IHC versus ISH (rS: 0.625; p<0.05) and IHC versus microarray (rS: 0.668; p<0.01), but in significant correlation for ISH versus microarray (rS: 0.861; p<0.001). The ISH method was superior to IHC, regarding robustness, sensitivity and specificity and will aid to further study expression levels of KCNJ3 in both malignant and physiological conditions. Y1 - 2016 U6 - https://doi.org/10.1136/jclinpath-2016-203798 SN - 1472-4146 SN - 0021-9746 VL - 69 IS - 12 SP - 1116 EP - 1121 ER - TY - GEN A1 - Kammerer, Sarah A1 - Sokolowski, Armin Andreas A1 - Hackl, Hubert A1 - Platzer, Dieter A1 - Jahn, Stephan Wenzel A1 - El-Heliebi, Amin A1 - Schwarzenbacher, Daniela A1 - Stiegelbauer, Verena A1 - Pichler, Martin A1 - Rezania, Simin A1 - Fiegl, Heidelinde A1 - Peintinger, Florentia A1 - Regitnig, Peter A1 - Höfler, Gerald A1 - Schreibmayer, Wolfgang A1 - Bauernhofer, Thomas T1 - KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients T2 - OncoTarget : open access impact journal N2 - Numerous studies showed abnormal expression of ion channels in different cancer types. Amongst these, the potassium channel gene KCNJ3 (encoding for GIRK1 proteins) has been reported to be upregulated in tumors of patients with breast cancer and to correlate with positive lymph node status. We aimed to study KCNJ3 levels in different breast cancer subtypes using gene expression data from the TCGA, to validate our findings using RNA in situ hybridization in a validation cohort (GEO ID GSE17705), and to study the prognostic value of KCNJ3using survival analysis. In a total of > 1000 breast cancer patients of two independent data sets we showed a) that KCNJ3 expression is upregulated in tumor tissue compared to corresponding normal tissue (p < 0.001), b) that KCNJ3 expression is associated with estrogen receptor (ER) positive tumors (p < 0.001), but that KCNJ3 expression is variable within this group, and c) that ER positive patients with high KCNJ3 levels have worse overall (p < 0.05) and disease free survival probabilities (p < 0.01), whereby KCNJ3 is an independent prognostic factor (p <0.05). In conclusion, our data suggest that patients with ER positive breast cancer might be stratified into high risk and low risk groups based on the KCNJ3 levels in the tumor. Y1 - 2016 U6 - https://doi.org/10.18632/oncotarget.13224 VL - 7 IS - 51 SP - 84705 EP - 84717 ER - TY - GEN A1 - Kotlarski, Sven A1 - Szabo, Peter A1 - Herrera, Sixto A1 - Räty, Olle A1 - Keuler, Klaus A1 - Soares, Pedro A1 - Cardoso, Rita M. A1 - Bosshard, Thomas A1 - Pagé, Christian A1 - Boberg, Fredrik A1 - Gutiérrez, José A1 - Isotta, Francesco A1 - Jaczewski, Adam A1 - Kreienkamp, Frank A1 - Liniger, Mark A1 - Lussana, Cristian A1 - Pianko‐Kluczyńska, Krystyna T1 - Observational uncertainty and regional climate model evaluation: A pan-European perspective T2 - International journal of climatology Y1 - 2019 U6 - https://doi.org/10.1002/joc.5249 SN - 1097-0088 SN - 0196-1748 VL - 39 IS - 9 SP - 3730 EP - 3749 ER - TY - GEN A1 - Trieschmann, Jan A1 - Ries, Stefan A1 - Bibinov, Nikita A1 - Awakowicz, Peter A1 - Mráz, Stanislav A1 - Schneider, Jochen M. A1 - Mussenbrock, Thomas T1 - Combined experimental and theoretical description of direct current magnetron sputtering of Al by Ar and Ar/N₂ plasma T2 - Plasma Sources Science and Technology Y1 - 2018 U6 - https://doi.org/10.1088/1361-6595/aac23e VL - 27 IS - 5 ER - TY - GEN A1 - Frömmel, Ulrike A1 - Lehmann, Werner A1 - Rödiger, Stefan A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Weinreich, Jörg A1 - Groß, Julia A1 - Roggenbuck, Dirk A1 - Zinke, Olaf A1 - Ansorge, Hermann A1 - Vogel, Steffen A1 - Klemm, Per A1 - Wex, Thomas A1 - Schröder, Christian A1 - Wieler, Lothar H. A1 - Schierack, Peter T1 - Adhesion of human and animal Escherichia coli strains in association with their virulence-associated genes and phylogenetic origins T2 - Applied and environmental microbiology N2 - Intestinal colonization is influenced by the ability of the bacterium to inhabit a niche, which is based on the expression of colonization factors. Escherichia coli carries a broad range of virulence-associated genes (VAGs) which contribute to intestinal (inVAGs) and extraintestinal (exVAGs) infection. Moreover, initial evidence indicates that inVAGs and exVAGs support intestinal colonization. We developed new screening tools to genotypically and phenotypically characterize E. coli isolates originating in humans, domestic pigs, and 17 wild mammal and avian species. We analyzed 317 isolates for the occurrence of 44 VAGs using a novel multiplex PCR microbead assay (MPMA) and for adhesion to four epithelial cell lines using a new adhesion assay. We correlated data for the definition of new adhesion genes. inVAGs were identified only sporadically, particularly in roe deer (Capreolus capreolus) and the European hedgehog ( Erinaceus europaeus). The prevalence of exVAGs depended on isolation from a specific host. Human uropathogenic E. coli isolates carried exVAGs with the highest prevalence, followed by badger (Meles meles) and roe deer isolates. Adhesion was found to be very diverse. Adhesion was specific to cells, host, and tissue, though it was also unspecific. Occurrence of the following VAGs was associated with a higher rate of adhesion to one or more cell lines: afa-dra, daaD, tsh, vat, ibeA, fyuA, mat, sfa-foc, malX, pic, irp2, and papC. In summary, we established new screening methods which enabled us to characterize large numbers of E. coli isolates. We defined reservoirs for potential pathogenic E. coli. We also identified a very broad range of colonization strategies and defined potential new adhesion genes. Y1 - 2013 U6 - https://doi.org/10.1128/AEM.01384-13 SN - 1098-5336 SN - 0099-2240 VL - 79 IS - 19 SP - 5814 EP - 5829 ER - TY - GEN A1 - Frömmel, Ulrike A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Weinreich, Jörg A1 - Groß, Julia A1 - Rödiger, Stefan A1 - Wex, Thomas A1 - Ansorge, Hermann A1 - Zinke, Olaf A1 - Schröder, Christian A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - Adhesion patterns of commensal and pathogenic Escherichia coli from humans and wild animals on human and porcine epithelial cell lines T2 - Gut Pathogens N2 - Abstract BACKGROUND: Different strategies of colonization or infection by E. coli result in formation of certain adhesion patterns which help also in classifying intestinal E. coli into pathotypes. Little is known about adhesion patterns and host- and tissue adaption of commensal E. coli and about E. coli originating in clinically healthy hosts carrying pathotype-specific virulence-associated genes. FINDINGS: Adhesion pattern of E. coli (n = 282) from humans and from 18 animal species were verified on intestinal human Caco-2 and porcine IPEC-J2 cells and, furthermore, for comparison on human urinary bladder 5637, porcine kidney PK-15 epithelial and HEp-2 cells. The analysis was carried out on 150,000 images of adhesion assays.Adhesion patterns were very diverse; 88 isolates were completely non-adherent, whereas 194 adhered to at least one cell line with the dominant adhesion patterns "diffusely distributed" and "microcolony formation". Adhesion patterns "chains" and "clumps" were also visible. Chain formation was mediated by the presence of epithelial cells. Clump formation was very specific on only the 5637 cell line. All enteropathogenic (eae+) E. coli (EPEC; n = 14) were able to form microcolonies which was cell line specific for each isolate. Most EPEC formed microcolonies on intestinal IPEC-J2 and Caco-2 but several also on urinary tract cells. Shigatoxin-producing (stx+) E. coli (n = 10) showed no specific adhesion patterns. CONCLUSIONS: E. coli isolates were highly diverse. Commensal and pathogenic isolates can adhere in various forms, including diffuse distribution, microcolonies, chains and clumps. Microcolony formation seems to be a global adhesion strategy also for commensal E. coli. Y1 - 2013 U6 - https://doi.org/10.1186/1757-4749-5-31 SN - 1757-4749 VL - 5 IS - 31 ER - TY - GEN A1 - Nalli, Cecilia A1 - Somma, Valentina A1 - Andreoli, Laura A1 - Büttner, Thomas A1 - Schierack, Peter A1 - Mahler, Michael A1 - Roggenbuck, Dirk A1 - Tincani, Angela T1 - Anti-phospholipid IgG antibodies detected by line immunoassay differentiate patients with anti-phospholipid syndrome and other autoimmune diseases T2 - Autoimmunity Highlights Y1 - 2018 U6 - https://doi.org/10.1007/s13317-018-0106-0 SN - 2038-3274 SN - 2038-0305 VL - 9 IS - 1 ER - TY - GEN A1 - Schierack, Peter A1 - Rödiger, Stefan A1 - Kolenda, Rafał A1 - Hiemann, Rico A1 - Berger, Enrico A1 - Grzymajlo, Krzysztof A1 - Swidsinski, Alexander A1 - Juretzek, Thomas A1 - Meissner, Dirk A1 - Mydlak, Karsten A1 - Reinhold, Dirk A1 - Nolan, Lisa K. A1 - Roggenbuck, Dirk T1 - Species-specific and pathotype-specific binding of bacteria to zymogen granule membrane glycoprotein 2 (GP2) T2 - Gut Y1 - 2015 U6 - https://doi.org/10.1136/gutjnl-2014-307854 SN - 1468-3288 SN - 0017-5749 VL - 64 IS - 3 SP - 517 EP - 519 ER - TY - GEN A1 - Guenther, Sebastian A1 - Groth, Ingrid A1 - Schierack, Peter A1 - Grabley, Susanne A1 - Munder, Thomas T1 - Direct detection of Kitasatospora species with a chaperone oligonucleotide microarray method lacking PCR amplification T2 - Journal of basic microbiology Y1 - 2008 U6 - https://doi.org/10.1002/jobm.200800038 SN - 1521-4028 SN - 0233-111X VL - 48 IS - 4 SP - 315 EP - 318 ER - TY - GEN A1 - Roggenbuck, Dirk A1 - Borghi, Maria Orietta A1 - Somma, Valentina A1 - Büttner, Thomas A1 - Schierack, Peter A1 - Hanack, Katja A1 - Grossi, Claudia A1 - Bodio, Caterina A1 - Macor, Paolo A1 - Landenberg, Philipp von A1 - Boccellato, Francesco A1 - Mahler, Michael A1 - Meroni, Pier Luigi T1 - Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers T2 - Arthritis Research & Therapy Y1 - 2016 U6 - https://doi.org/10.1186/s13075-016-1018-x SN - 1465-9913 SN - 1478-6362 VL - 18 IS - 111 ER - TY - GEN A1 - Wilczek, Sebastian A1 - Trieschmann, Jan A1 - Schulze, Julian A1 - Donko, Zoltan A1 - Brinkmann, Ralf Peter A1 - Mussenbrock, Thomas T1 - Disparity between current and voltage driven capacitively coupled radio frequency discharges T2 - Plasma Sources Science and Technology Y1 - 2018 U6 - https://doi.org/10.1088/1361-6595/aae5c1 SN - 1361-6595 SN - 0963-0252 VL - 27 IS - 12 ER - TY - GEN A1 - Berger, Birk A1 - You, Kwangho A1 - Lee, Hyo-Chang A1 - Mussenbrock, Thomas A1 - Awakowicz, Peter A1 - Schulze, Julian T1 - Observation of the generation of multiple electron beams during a single sheath expansion phase in capacitive RF plasmas T2 - Plasma Sources Science and Technology Y1 - 2018 U6 - https://doi.org/10.1088/1361-6595/aaefc7 SN - 1361-6595 SN - 0963-0252 VL - 27 IS - 12 ER - TY - GEN A1 - Gibson, Andrew R. A1 - Donkó, Zoltán A1 - Alelyani, Layla A1 - Bischoff, Lena A1 - Hübner, Gerrit A1 - Bredin, Jérôme A1 - Doyle, Scott A1 - Korolov, Ihor A1 - Niemi, Kari A1 - Mussenbrock, Thomas A1 - Hartmann, Peter A1 - Dedrick, James P. A1 - Schulze, Julian A1 - Gans, Timo A1 - O'Connell, Deborah T1 - Disrupting the spatio-temporal symmetry of the electron dynamics in atmospheric pressure plasmas by voltage waveform tailoring T2 - Plasma Sources Science and Technology Y1 - 2019 U6 - https://doi.org/10.1088/1361-6595/aaf535 SN - 1361-6595 SN - 0963-0252 VL - 28 IS - 1 ER - TY - GEN A1 - Bischoff, Lena A1 - Hübner, Gerrit A1 - Korolov, Ihor A1 - Donkó, Zoltán A1 - Hartmann, Peter A1 - Gans, Timo A1 - Held, Julian A1 - Schulz-von der Gathen, Volker A1 - Liu, Yue A1 - Mussenbrock, Thomas A1 - Schulze, Julian T1 - Experimental and computational investigations of electron dynamics in micro atmospheric pressure radio-frequency plasma jets operated in He/N2 mixtures T2 - Plasma Sources Science and Technology Y1 - 2018 U6 - https://doi.org/10.1088/1361-6595/aaf35d SN - 1361-6595 SN - 0963-0252 VL - 27 IS - 12 ER - TY - GEN A1 - Liebsch, Claudia A1 - Rödiger, Stefan A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Weinreich, Jörg A1 - Fruth, Angelika A1 - Roggenbuck, Dirk A1 - Lehmann, Werner A1 - Schedler, Uwe A1 - Juretzek, Thomas A1 - Schierack, Peter T1 - Solid-phase microbead array for multiplex O-serotyping of Escherichia coli T2 - Microchimica Acta Y1 - 2017 U6 - https://doi.org/10.1007/s00604-017-2088-4 SN - 0026-3672 SN - 1436-5073 VL - 184 IS - 5 SP - 1405 EP - 1415 ER - TY - GEN A1 - Beirow, Bernd A1 - Kühhorn, Arnold A1 - Figaschewsky, Felix A1 - Hönisch, Peter A1 - Giersch, Thomas A1 - Schrape, Sven T1 - Model update and validation of a mistuned high-pressure compressor blisk T2 - The Aeronautical Journal N2 - In order to prepare an advanced 4-stage high-pressure compressor rig test campaign, details regarding both accomplishment and analysis of preliminary experiments are provided in this paper. The superior objective of the research project is to contribute to a reliable but simultaneously less conservative design of future high pressure blade integrated disks (blisk). It is planned to achieve trend-setting advances based on a close combination of both numerical and experimental analyses. The analyses are focused on the second rotor of this research compressor, which is the only one being manufactured as blisk. The comprehensive test program is addressing both surge and forced response analyses e.g. caused by low engine order excitation. Among others the interaction of aeroelastics and blade mistuning is demanding attention in this regard. That is why structural models are needed, allowing for an accurate forced response prediction close to reality. Furthermore, these models are required to support the assessment of blade tip timing (BTT) data gathered in the rig tests and strain gauge (s/g) data as well. To gain the maximum information regarding the correlation between BTT data, s/g-data and pressure gauge data, every blade of the second stage rotor (28 blades) is applied with s/g. However, it is well known that s/g on blades can contribute additional mistuning that had to be considered upon updating structural models. Due to the relevance of mistuning, efforts are made for its accurate experimental determination. Blade-by-blade impact tests according to a patented approach are used for this purpose. From the research point of view, it is most interesting to determine both the effect s/g-instrumentation and assembling the compressor stages on blade frequency mistuning. That is why experimental mistuning tests carried out immediately after manufacturing the blisk are repeated twice, namely, after s/g instrumentation and after assembling. To complete the pre-test program, the pure mechanical damping and modal damping ratios dependent on the ambient pressure are experimentally determined inside a pressure vessel. Subsequently the mistuning data gained before is used for updating subset of nominal system mode (SNM) models. Aerodynamic influence coefficients (AICs) are implemented to take aeroelastic interaction into account for forced response analyses. Within a comparison of different models, it is shown for the fundamental flap mode (1F) that the s/g instrumentation significantly affects the forced response, whereas the impact of assembling the compressor plays a minor role. KW - Blisk KW - Mistuning KW - Aerodynamic damping Y1 - 2019 U6 - https://doi.org/10.1017/aer.2018.149 SN - 2059-6464 SN - 0001-9240 VL - 123 IS - 1260 SP - 230 EP - 247 ER - TY - GEN A1 - Korolov, Ihor A1 - Donko, Zoltan A1 - Hübner, Gerrit A1 - Bischoff, Lena A1 - Hartmann, Peter A1 - Gans, Timo A1 - Liu, Yue A1 - Mussenbrock, Thomas A1 - Schulze, Julian T1 - Control of electron dynamics, radical and metastable species generation in atmospheric pressure RF plasma jets by Voltage Waveform Tailoring T2 - Plasma Sources Science and Technology Y1 - 2019 U6 - https://doi.org/10.1088/1361-6595/ab38ea SN - 0963-0252 SN - 1361-6595 VL - 28 IS - 9 ER - TY - GEN A1 - Schneider, Robert A1 - Simon, Sylvio A1 - Täschner, Dirk A1 - Hernschier, Stephan A1 - Rieder, Thomas A1 - Magister, Jan A1 - Biegel, Peter T1 - Untersuchungen zur Wirkung von Kreisformabweichung und Exzentrizität auf das Laufverhalten von Tragrollen in Hochleistungsgurtförderanlagen T2 - 8. Kolloquium Fördertechnikim Bergbau - Tagungsband N2 - Während im Tagebau früher das Augenmerk primär auf einen zuverlässigen und wirtschaftlichen Abbau und Transport von Rohstoffen gerichtet war, spielen heutzutage noch einige andere Aspekte eine entscheidende Rolle. Da die Abbaugebiete immer weiter in besiedelte Gegenden vordringen und die Vorgaben im Umweltschutz sich verschärfen, ist der Betreiber in zunehmendem Maße bestrebt, unter anderem die Geräuschemissionen der Tagebaugroßgeräte zu senken. Da sich speziell Gurtförderanlagen im Bereich des Vorschnitts über große Entfernungen erstrecken und an den Rändern der Tagebaue verlaufen, tragen diese zu einem großen Teil zur Geräuschemission bei. Tragrollen sind oft zu Tausenden in den Förderanlagen verbaut und bei der akustischen Wirkung von entscheidender Bedeutung. Um eine Gesundheitsgefährdung für die beschäftigten Mitarbeiter durch Lärm zu vermeiden und die Auswirkungen auf angrenzende Siedlungen auf ein Mindestmaß zu begrenzen, existieren gesetzliche Vorschriften und Richtlinien. Die Gesetze und Verordnungen zum Umweltschutz und Arbeitsschutz sollen eine Reduzierung der Lärmimmissionen erreichen. Laut den Immissionsrichtwerten1 der Technischen Anleitung zum Schutz gegen Lärm (TA Lärm) darf nachts in Kerngebieten, Dorf- und Mischgebieten der Beurteilungspegel von 45 dB(A) nicht überschritten werden, in reinen Wohngebieten liegt die Grenze sogar bei 35 dB(A). Zum Vergleich: Eine leise Unterhaltung oder leise Musik wird mit einem Schalldruckpegel von 40 dB(A) angegeben. Der durch den Betrieb der Gurtförderanlagen entstehende meterbezogene Schallleistungspegel LW beträgt im Durchschnitt etwa 80 bis 100 dB(A). Durch Reduktion der Schallemission könnten die Planungen der Streckenverläufe optimiert werden, was zu wirtschaftlichen Einsparungen führt. Weiterhin ist, wenn die für Tagebauanlagen zu beachtenden Richtwerte eingehalten werden, auch die Genehmigung für die Einrichtung und den Betrieb solcher Anlagen einfacher abzusichern. Um genaue Kenntnisse über die Schallemission von Tragrollen zu erlangen, wurde in Zusammenarbeit der ehemaligen VEM AG (jetzt LEAG) und der ehemaligen Hochschule Lausitz (jetzt BTU Cottbus-Senftenberg) ein Tragrollenprüfstand entwickelt. Im Rahmen einer Baugruppenprüfung auf diesem Prüfstand werden akustische und mechanische Kenngrößen von Tragrollen untersucht. Bestandteile dieser Untersuchungen sind: - Hochfahrprüfläufe – Dabei wird eine Tragrolle unter Prüflast auf eine Umfangsgeschwindigkeit von 10 m/s beschleunigt und der Schalldruckpegel aufgezeichnet. Dies ermöglicht die Berechnung der Schallemission in Abhängigkeit von der Umfangsgeschwindigkeit. - Ermittlung des Abklingverhaltens – Durch Anschlagversuche wird das Eigenschwing- und Dämpfungsverhalten einer Tragrolle erfasst. - Erfassung der Tragrollengeometrie – Die präzise Beschreibung der Geometrie des Tragrollenmantels ermöglicht Rückschlüsse auf mögliche Anregungsursachen. KW - Tragrolle KW - Tragrollenprüfstand KW - Lärm KW - Rundlaufabweichung KW - Wälzlager KW - Akustische Kamera KW - Lärmminderung KW - Wälzlagerverschleiß Y1 - 2018 UR - https://www.bergbau.tu-clausthal.de/fileadmin/homes/tiefbau_files/Veranstaltungen/Tagungsband_-_Foerdertechnik_-_2018.pdf SN - 978-3-86948-621-5 SP - 99 EP - 110 PB - Papierflieger Verlag GmbH CY - Clausthal-Zellerfeld, 2018 ER - TY - GEN A1 - Simon, Sylvio A1 - Biegel, Peter A1 - Hernschier, Stephan A1 - Täschner, Dirk A1 - Rieder, Thomas A1 - Magister, Jan A1 - Schneider, Robert A1 - Fritsch, Tim T1 - 10 Jahre Tragrollenprüfstand : Vortragsband zum Festkolloquium am 18. Oktober 2017 N2 - Tagungsband mit 6 Vorträgen im Rahmen des Jubiläumskolliquiums KW - Tragrolle KW - Tragrollenprüfstand KW - Lärm KW - Rundlaufabweichung KW - Wälzlager KW - Unwucht KW - Gurtförderanlage KW - Gutförderer KW - Bandanlage Y1 - 2017 U6 - https://doi.org/10.5281/zenodo.3457376 PB - BTU CY - Senftenberg ER - TY - GEN A1 - Korolov, Ihor A1 - Leimkühler, Marc A1 - Boeke, Marc A1 - Donkó, Zoltan A1 - Schulz-von der Gathen, Volker A1 - Bischoff, Lena A1 - Hübner, Gerrit A1 - Hartmann, Peter A1 - Gans, Timo A1 - Liu, Yue A1 - Mussenbrock, Thomas A1 - Schulze, Julian T1 - Helium metastable species generation in atmospheric pressure RF plasma jets driven by tailored voltage waveforms in mixtures of He and N 2 T2 - Journal of Physics D: Applied Physics Y1 - 2020 U6 - https://doi.org/10.1088/1361-6463/ab6d97 SN - 1361-6463 VL - 53 ER - TY - GEN A1 - Wilczek, Sebastian A1 - Schulze, Julian A1 - Brinkmann, Ralf Peter A1 - Donkó, Zoltan A1 - Trieschmann, Jan A1 - Mussenbrock, Thomas T1 - Electron dynamics in low pressure capacitively coupled radio frequency discharges T2 - Journal of Applied Physics Y1 - 2020 U6 - https://doi.org/10.1063/5.0003114.1 VL - 127 IS - 18 ER - TY - GEN A1 - Schöberl, Florian A1 - Pradhan, Cauchy A1 - Irving, Stephanie A1 - Buerger, Katharina A1 - Xiong, Guoming A1 - Kugler, Günter A1 - Kohlbecher, Stefan A1 - Engmann, Julia A1 - Werner, Philipp A1 - Brendel, Matthias A1 - Schneider, Erich A1 - Perneczky, Robert A1 - Jahn, Klaus A1 - Fougère, Christian la A1 - Bartenstein, Peter A1 - Brandt, Thomas A1 - Dietrich, Marianne A1 - Zwergal, Andreas T1 - Real-space navigation testing differentiates between amyloid-positive and -negative aMCI T2 - Neurology : official journal of the American Academy of Neurology Y1 - 2020 UR - https://n.neurology.org/content/94/8/e861 U6 - https://doi.org/10.1212/WNL.0000000000008758 SN - 1526-632X VL - 94 IS - 8 SP - e861 EP - e873 ER - TY - GEN A1 - Schöberl, Florian A1 - Irving, Stephanie A1 - Pradhan, Cauchy A1 - Bardins, Stanislav A1 - Trapp, Christoph A1 - Schneider, Erich A1 - Kugler, Günter A1 - Bartenstein, Peter A1 - Dietrich, Marianne A1 - Brandt, Thomas A1 - Zwergal, Andreas T1 - Prolonged allocentric navigation deficits indicate hippocampal damage in TGA T2 - Neurology : official journal of the American Academy of Neurology N2 - Objective To investigate long-term recovery of allocentric and egocentric spatial orientation as a sensitive marker for hippocampal and extrahippocampal network function in transient global amnesia (TGA). Methods A group of 18 patients with TGA performed an established real-space navigation paradigm, requiring allo- and egocentric spatial orientation abilities, 3 days (postacute stage) and 3 months (follow-up) after symptom onset. Visual exploration behavior and navigation strategy were documented by a gaze-controlled, head-fixed camera. Allo- and egocentric spatial orientation performance was compared to that of 12 age-matched healthy controls. Navigation-induced brain activations were measured using [18F]-fluorodeoxyglucose-PET in a subgroup of 8 patients in the postacute stage and compared to those of the controls. Results In the postacute stage, the patients navigated worse and had higher error rates than controls in allocentric (p = 0.002), but not in egocentric, route planning (p = 0.30), despite complete recovery of verbal (p = 0.58) and figural memory (p = 0.11). Until follow-up, allocentric navigation deficits improved, but higher error rates and reduced use of shortcuts persisted (p < 0.0001). Patients still exhibited relatively more fixations of unique landmarks during follow-up (p = 0.05). PET measurements during the postacute stage showed increased navigation-induced brain activations in the right hippocampus, bilateral retrosplenial, parietal, and mesiofrontal cortices, and cerebellar dentate nucleus in patients compared to controls (p < 0.005). Conclusions Patients with TGA show selective and prolonged deficits of allocentric spatial orientation. Activations in right hippocampal and extrahippocampal hubs of the cerebral navigation network functionally substitute for the deficit in creating and updating the internal cognitive map in TGA. Y1 - 2019 UR - https://n.neurology.org/content/92/3/e234/tab-article-info U6 - https://doi.org/10.1212/WNL.0000000000006779 SN - 0028-3878 SN - 1526-632X VL - 92 IS - 3 SP - e234 EP - e243 ER - TY - GEN A1 - Jurischka, Christoph A1 - Dinter, Franziska A1 - Efimova, Anastasia A1 - Weiss, Romano A1 - Schiebel, Juliane A1 - Schulz, Christian A1 - Fayziev, Bekzodjon A1 - Schierack, Peter A1 - Fischer, Thomas A1 - Rödiger, Stefan T1 - An explorative study of polymers for 3D printing of bioanalytical test systems T2 - Clinical Hemorheology and Microcirculation N2 - Background: The 3D printing is relevant as a manufacturing technology of functional models for forensic, pharmaceutical and bioanalytical applications such as drug delivery systems, sample preparation and point-of-care tests. Objective: Melting behavior and autofluorescence of materials are decisive for optimal printing and applicability of the product which are influenced by varying unknown additives. Methods: We have produced devices for bioanalytical applications from commercially available thermoplastic polymers using a melt-layer process. We characterized them by differential scanning calorimetry, fluorescence spectroscopy and functional assays (DNA capture assay, model for cell adhesion, bacterial adhesion and biofilm formation test). Results: From 14 tested colored, transparent and black materials we found only deep black acrylonitrile-butadiene-styrene (ABS) and some black polylactic acid (PLA) useable for fluorescence-based assays, with low autofluorescence only in the short-wave range of 300-400 nm. PLA was suitable for standard bioanalytical purposes due to a glass transition temperature of approximately 60°C, resistance to common laboratory chemicals and easy print processing. For temperature-critical methods, such as hybridization reactions up to 90°C, ABS was better suited. Conclusions: Autofluorescence was not a disadvantage per se but can also be used as a reference signal in assays. The rapid development of individual protocols for sample processing and analysis required the availability of a material with consistent quality over time. For fluorescence-based assays, the use of commercial standard materials did not seem to meet this requirement. KW - Thermal analysis KW - 3D Printing Y1 - 2020 UR - https://pubmed.ncbi.nlm.nih.gov/31929149/ U6 - https://doi.org/10.3233/CH-190713 SN - 1875-8622 VL - 75 IS - 1 SP - 57 EP - 84 ER - TY - GEN A1 - Klich, Maximilian A1 - Wilczek, Sebastian A1 - Janssen, Jesper Frederikus Jacobus A1 - Brinkmann, Ralf Peter A1 - Mussenbrock, Thomas A1 - Trieschmann, Jan T1 - Ion dynamics in capacitively coupled argon–xenon discharges T2 - Plasma Sources Science and Technology Y1 - 2021 U6 - https://doi.org/10.1088/1361-6595/ac02b0 SN - 1361-6595 VL - 30 IS - 6 ER - TY - GEN A1 - Schröder, Lena A1 - Werder, Dina von A1 - Ramaioli, Cecilia A1 - Wachtler, Thomas A1 - Henningsen, Peter A1 - Glasauer, Stefan A1 - Lehnen, Nadine T1 - Unstable Gaze in Functional Dizziness: A Contribution to Understanding the Pathophysiology of Functional Disorders T2 - Frontiers in Neuroscience N2 - Objective: We are still lacking a pathophysiological mechanism for functional disorders explaining the emergence and manifestation of characteristic, severely impairing bodily symptoms like chest pain or dizziness. A recent hypothesis based on the predictive coding theory of brain function suggests that in functional disorders, internal expectations do not match the actual sensory body states, leading to perceptual dysregulation and symptom perception. To test this hypothesis, we investigated the account of internal expectations and sensory input on gaze stabilization, a physiologically relevant parameter of gaze shifts, in functional dizziness. Methods: We assessed gaze stabilization in eight functional dizziness patients and 11 healthy controls during two distinct epochs of large gaze shifts: during a counter- rotation epoch (CR epoch), where the brain can use internal models, motor planning, and resulting internal expectations to achieve internally driven gaze stabilization; and during an oscillation epoch (OSC epoch), where, due to terminated motor planning, no movement expectations are present, and gaze is stabilized by sensory input alone. Results: Gaze stabilization differed between functional patients and healthy controls only when internal movement expectations were involved [F(1,17) = 14.63, p = 0.001, and partial η2 = 0.463]: functional dizziness patients showed reduced gaze stabilization during the CR (p = 0.036) but not OSC epoch (p = 0.26). Conclusion: While sensory-driven gaze stabilization is intact, there are marked, well- measurable deficits in internally-driven gaze stabilization in functional dizziness pointing at internal expectations that do not match actual body states. This experimental evidence supports the perceptual dysregulation hypothesis of functional disorders and is an important step toward understanding the underlying pathophysiology. Y1 - 2021 U6 - https://doi.org/10.3389/fnins.2021.685590 SN - 1662-453X SN - 1662-4548 VL - 15 ER - TY - GEN A1 - Schmidt, Carsten A1 - Borcherding, Heike A1 - Thiele, Thomas A1 - Schedler, Uwe A1 - Werner, Franziska A1 - Rödiger, Stefan A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - Fluorescence-encoded poly (methyl metharcylate) nanoparticles for a lateral flow assay detecting IgM autoantibodies in rheumatoid arthritis T2 - Analytical biochemistry Y1 - 2021 U6 - https://doi.org/10.1016/journal.ppat.1010118 SN - 1096-0309 VL - Vol. 633 ER - TY - GEN A1 - Emmenegger, Marc A1 - Kumar, Sreedhar Saseendran A1 - Emmenegger, Vishalini A1 - Malinauskas, Tomas A1 - Büttner, Thomas A1 - Rose, Laura A1 - Schierack, Peter A1 - Sprinzl, Martin F. A1 - Sommer, Clemens J. A1 - Lackner, Karl J. A1 - Aguzzi, Adriano A1 - Roggenbuck, Dirk A1 - Frauenknecht, Katrin B. M. T1 - Anti-prothrombin autoantibodies enriched after infection with SARS-CoV-2 and influenced by strength of antibody response against SARS-CoV-2 proteins T2 - PLoS pathogens Y1 - 2021 U6 - https://doi.org/10.1371/journal.ppat.1010118 SN - 1553-7374 VL - 17 IS - 12 ER - TY - GEN A1 - Uchino, Kazuki A1 - Raab, Alexandra A1 - Bonhage, Alexander A1 - Schneider, Anna A1 - Raab, Thomas A1 - Wechler, Klaus-Peter A1 - Bauriegel, Albrecht T1 - Spatial heterogeneity of buried and recent soils in a drift sand area in North-Eastern Germany T2 - EGU General Assembly 2022, Vienna, Austria, 23–27 May 2022 N2 - In the North European Lowland, on the sandy deposits of the Weichselian glaciation, soils developed during periods of landscape stability are often conserved under windblown sand. However, small-scale changes of sediments and other soil forming factors can result in high spatial variation of soil properties in these landscapes; and relocation of soil material by geomorphic processes further increases the spatial heterogeneity of the soil landscape. These spatial variations in soil properties and conservation need to be considered in order to correctly decipher and interpret the buried soils as records of past environmental conditions. In the forefield of the open-cast mine Cottbus-Nord, archaeological excavations in a dune and drift sand area revealed widespread buried soils of different characteristics. The densely spaced excavation trenches give exceptionally good insights into the pedosphere, allow for reconstructing the distribution of fossil and recent soils in a high spatial resolution, and offer good opportunities to improve the understanding of spatial and temporal patterns of soil formation. Remains of postpleistocene hunter-gatherer campsites were documented in archaeological excavations and found to be associated with a buried soil horizon. We recorded the stratigraphy of soil profiles along more than 15 trenches within an area of about 20 ha, and additionally described the position of buried soils from GPR surveys and microdrone photogrammetry. In a recently opened, 455 m long trench, all characteristic soils and sediments of the study region could be observed and stratigraphically connected. Within this trench, four profiles were identified for further research. Each profile was classified and described according to WRB and German Guidelines for Soil Mapping; and was sampled and investigated through laboratory analyses including determination of organic matter, total carbon and nitrogen contents, soil colour identification, texture analysis, magnetic susceptibility measurement, metal content analysis using X-ray fluorescence analyzer and pH measurement. The compaction and cementation of soil horizons was assessed in situ with a pocket penetrometer. Results show a small-scale mosaic of soils developed on fluvio-aeolian, limnic and aeolian sediments, high spatial variations in pedogenesis due to varying groundwater influence and intensity of horizontal and vertical leachate transport, and high variations in the erosion or conservation of fossil soils. The soil and sediment stratigraphy reflects several phases of landscape development: i) the formation of a Late Pleistocene soil on fluvio-aeolian deposits, ii) a fossilization by aeolian sands, iii) a stability phase with intensive podsolization and peat formation, and iv) a land use-induced aeolian remobilization of the sands. Y1 - 2022 U6 - https://doi.org/10.5194/egusphere-egu22-2354 ER - TY - GEN A1 - Klimczak, Peter A1 - Halamuda, Thomas T1 - Twitter-Studie: Zeitungen als (Hidden) Champions auf Twitter T2 - BDZV-Jahresreport DIGITAL N2 - Zeitungen gehören zu den Leitmedien auf der Diskursplattform Twitter. Sie versorgen die Community mit tagesaktuellem Content und mischen auch im Diskurs mit. Insbesondere Letzteres bringt jedoch nicht nur Vor-, sondern auch Nachteile. KW - Zeitungen KW - Leitmedien KW - Twitter KW - Massenmedien KW - Tweets Y1 - 2022 UR - https://www.halamuda.com/wp-content/uploads/2022/07/BDZV_Jahresreport_Digital_2022-Zeitungen-auf-Twitter.pdf VL - 2022 SP - 152 EP - 156 ER - TY - GEN A1 - Förster, Benjamin A1 - Langendörfer, Peter A1 - Hinze, Thomas T1 - Novel Approach to a Plant Inspired Distributed Security Scheme for Wireless Sensor Networks T2 - 12th Mediterranean Conference on Embedded Computing (MECO), Budva, Montenegro, 2023 N2 - Energy efficiency is a key factor for the longevity of wireless sensor networks (WSNs). Most representatives of the plants have evolved to be highly energy-efficient in their survival strategies, despite their limited resources. Plants have to deal with a variety of threats originating from different herbivores and microbial pathogens while handling a number of abiotic stress factors. For plants and WSNs, different defence mechanisms impose different fitness costs and therefore the costs and benefits have to be well-balanced. This way, plants are able to not only conquer a large variety of different attacks but also handle several different simultaneous attacks adequately. To react early and adapt to upcoming threats, plants within a network are capable of signalling each other within a certain distance about ongoing attacks. The biological strategies of plants in terms of signalling and defence, as well as their energy and resource limitations, share significant similarities with WSNs. This study aims to explore these similarities and demonstrates the correspondence between the biological concepts and WSNs. Additionally, we present a novel approach to enhancing security in WSNs through a cooperative distributed security scheme inspired by key factors of plant defence mechanisms, with the goal of reducing the energy constraints and maximising the longevity of the network. KW - Wireless sensor networks KW - Pathogens KW - Embedded computing KW - Cyber-physical systems Y1 - 2023 SN - 979-8-3503-2291-0 SN - 979-8-3503-2290-3 U6 - https://doi.org/10.1109/MECO58584.2023.10154949 SN - 2637-9511 ER - TY - GEN A1 - Förster, Benjamin A1 - Langendörfer, Peter A1 - Hinze, Thomas T1 - Determining Distributions of Security Means for Wireless Sensor Networks based on the Model of a Neighbourhood Watch T2 - arXiv N2 - Neighbourhood watch is a concept that allows a community to distribute a complex security task in between all members. Members of the community carry out individual security tasks to contribute to the overall security of it. It reduces the workload of a particular individual while securing all members and allowing them to carry out a multitude of security tasks. Wireless sensor networks (WSNs) are composed of resource-constraint independent battery driven computers as nodes communicating wirelessly. Security in WSNs is essential. Without sufficient security, an attacker is able to eavesdrop the communication, tamper monitoring results or deny critical nodes providing their service in a way to cut off larger network parts. The resource-constraint nature of sensor nodes prevents them from running full-fledged security protocols. Instead, it is necessary to assess the most significant security threats and implement specialised protocols. A neighbourhood-watch inspired distributed security scheme for WSNs has been introduced by Langend\"orfer. Its goal is to increase the variety of attacks a WSN can fend off. A framework of such complexity has to be designed in multiple steps. Here, we introduce an approach to determine distributions of security means on large-scale static homogeneous WSNs. Therefore, we model WSNs as undirected graphs in which two nodes connected iff they are in transmission range. The framework aims to partition the graph into $n$ distinct security means resulting in the targeted distribution. The underlying problems turn out to be NP hard and we attempt to solve them using linear programs (LPs). To evaluate the computability of the LPs, we generate large numbers of random {\lambda}-precision unit disk graphs (UDGs) as representation of WSNs. For this purpose, we introduce a novel {\lambda}-precision UDG generator to model WSNs with a minimal distance in between nodes. Y1 - 2023 U6 - https://doi.org/10.48550/arXiv.2212.09050 ER - TY - GEN A1 - Förster, Benjamin A1 - Langendörfer, Peter A1 - Hinze, Thomas T1 - Determining Distributions of Security Means for WSNs Based on the Model of a Neighborhood Watch T2 - IEEE Access Y1 - 2024 U6 - https://doi.org/10.1109/ACCESS.2024.3404816 SN - 2169-3536 VL - 12 SP - 74343 EP - 74366 PB - Institute of Electrical and Electronics Engineers (IEEE) ER - TY - GEN A1 - Förster, Benjamin A1 - Langendörfer, Peter A1 - Hinze, Thomas T1 - Security mean distribution in WSNs for cooperative schemes T2 - Vorträge : iCCC2024 - iCampµs Cottbus Conference 2024-05-14 - 2024-05-16 Cottbus Y1 - 2024 U6 - https://doi.org/10.5162/iCCC2024/1.2 SP - 38 EP - 41 PB - AMA Service GmbH CY - Von-Münchhausen-Str. 49, 31515 Wunstorf, Germany ER - TY - GEN A1 - Becker, L. A1 - Storck, Peter A1 - Liu, Y. A1 - Schwalb, G. A1 - Schroeder, Thomas A1 - Fischer, Inga Anita A1 - Albrecht, M. T1 - Optimizing misfit dislocation glide kinetics for enhanced threading dislocation density reduction in Si1− xGex/Si (001) layers through dynamic growth rate control T2 - Journal of Applied Physics Y1 - 2024 U6 - https://doi.org/10.1063/5.0204318 SN - 0021-8979 SN - 1089-7550 VL - 135 IS - 20 SP - 10 ER - TY - GEN A1 - Martre, Pierre A1 - Dueri, Sibylle A1 - Guarin, Jose Rafael A1 - Ewert, Frank A1 - Webber, Heidi A1 - Calderini, Daniel A1 - Molero, Gemma A1 - Reynolds, Matthew A1 - Miralles, Daniel A1 - Garcia, Guillermo A1 - Brown, Hamish A1 - George, Mike A1 - Craigie, Rob A1 - Cohan, Jean‐Pierre A1 - Deswarte, Jean-Charles A1 - Slafer, Gustavo A. A1 - Giunta, Francesco A1 - Cammarano, Davide A1 - Ferrise, Roberto A1 - Gaiser, Thomas A1 - Gao, Yujing A1 - Hochman, Zvi A1 - Hoogenboom, Gerrit A1 - Hunt, Leslie A. A1 - Kersebaum, Kurt C. A1 - Nendel, Claas A1 - Padovan, Gloria A1 - Ruane, Alex C. A1 - Srivastava, Amit Kumar A1 - Stella, Tommaso A1 - Supit, Iwan A1 - Thorburn, Peter A1 - Wang, Enli A1 - Wolf, Joost A1 - Zhao, Chuang A1 - Zhao, Zhigan A1 - Asseng, Senthold T1 - Global needs for nitrogen fertilizer to improve wheat yield under climate change T2 - Nature Plants Y1 - 2024 U6 - https://doi.org/10.1038/s41477-024-01739-3 SN - 2055-0278 VL - 10 IS - 7 SP - 1081 EP - 1090 PB - Springer Science and Business Media LLC ER - TY - GEN A1 - Martre, Pierre A1 - Dueri, Sibylle A1 - Brown, Hamish A1 - Asseng, Senthold A1 - Ewert, Frank A1 - Webber, Heidi A1 - George, Mike A1 - Craigie, Rob A1 - Guarin, Jose Rafael A1 - Pequeno, Diego A1 - Stella, Tommaso A1 - Ahmed, Mukhtar A1 - Alderman, Phillip A1 - Basso, Bruno A1 - Berger, Andres A1 - Bracho Mujica, Gennady A1 - Cammarano, Davide A1 - Chen, Yi A1 - Dumont, Benjamin A1 - Rezaei, Ehsan Eyshi A1 - Fereres, Elias A1 - Ferrise, Roberto A1 - Gaiser, Thomas A1 - Gao, Yujing A1 - Garcia-Vila, Margarita A1 - Gayler, Sebastian A1 - Hochman, Zvi A1 - Hoogenboom, Gerrit A1 - Kersebaum, Kurt C. A1 - Nendel, Claas A1 - Olesen, Jørgen A1 - Padovan, Gloria A1 - Palosuo, Taru A1 - Priesack, Eckart A1 - Pullens, Johannes A1 - Rodríguez, Alfredo A1 - Rötter, Reimund P. A1 - Ruiz Ramos, Margarita A1 - Semenov, Mikhail A1 - Senapati, Nimai A1 - Siebert, Stefan A1 - Srivastava, Amit Kumar A1 - Stöckle, Claudio A1 - Supit, Iwan A1 - Tao, Fulu A1 - Thorburn, Peter A1 - Wang, Enli A1 - Weber, Tobias A1 - Xiao, Liujun A1 - Zhao, Chuang A1 - Zhao, Jin A1 - Zhao, Zhigan A1 - Zhu, Yan T1 - Winter wheat experiments to optimize sowing dates and densities in a high-yielding environment in New Zealand: field experiments and AgMIP-Wheat multi-model simulations T2 - Open Data Journal for Agricultural Research N2 - This paper describes the data set that was used to test the accuracy of twenty-nine crop models in simulating the effect of changing sowing dates and sowing densities on wheat productivity for a high-yielding environment in New Zealand. The data includes one winter wheat cultivar (Wakanui) grown during six consecutive years, from 2012-2013 to 2017-2018, at two farms located in Leeston and Wakanui in Canterbury, New Zealand. The simulations were carried out in the framework of the Agricultural Model Intercomparison and Improvement Project for wheat (AgMIP-Wheat). Data include local daily weather data, soil profile characteristics and initial conditions, crop measurements at maturity (grain, stem, chaff and leaf dry weight, ear number and grain number, grain unit dry weight), and at stem elongation and anthesis (total above ground dry biomass, leaf number per stem and leaf area index). Several in-season measurements of the normalized difference vegetation index (NDVI) and the fraction of intercepted photosynthetically active radiation (FIPAR) are also available. The crop model simulations include both daily in-season and end-of-season results from twenty-nine wheat models. KW - field experimental data KW - multi-crop model ensemble KW - sowing date KW - sowing density KW - winter wheat KW - yield potential Y1 - 2024 U6 - https://doi.org/10.18174/odjar.v10i0.18442 SN - 2352-6378 VL - 10 SP - 14 EP - 21 PB - Wageningen University and Research ER - TY - GEN A1 - Boetzl, Fabian A1 - Sponsler, Douglas A1 - Albrecht, Matthias A1 - Batáry, Péter A1 - Birkhofer, Klaus A1 - Knapp, Michal A1 - Krauss, Jochen A1 - Maas, Bea A1 - Martin, Emily A. A1 - Sirami, Clélia A1 - Sutter, Louis A1 - Bertrand, Colette A1 - Baillod, Aliette A1 - Bota, Gerard A1 - Bretagnolle, Vincent A1 - Brotons, Lluís A1 - Frank, Thomas A1 - Fusser, Moritz A1 - Giralt, David A1 - González, Ezequiel A1 - Hof, Anouschka A1 - Luka, Henryk A1 - Marrec, Ronan A1 - Nash, Michael A1 - Ng, Katherina A1 - Plantegenest, Manuel A1 - Poulin, Brigitte A1 - Siriwardena, Gavin A1 - Zubair-Anjum, Muhammad A1 - Entling, Martin A1 - Steffan-Dewenter, Ingolf A1 - Schirmel, Jens T1 - Distance functions of carabids in crop fields depend on functional traits, crop type and adjacent habitat: a synthesis T2 - Proceedings Royal Society. Series B, Biological sciences Y1 - 2024 U6 - https://doi.org/10.1098/rspb.2023.2383 SN - 1471-2954 VL - Vol. 291 SP - 1 EP - 10 ER - TY - GEN A1 - Förster, Benjamin A1 - Hinze, Thomas A1 - Langendorfer, Peter T1 - Topology- and Resource-Based Distribution Scheme for Collaborative Security-Focused Design Space Exploration in Large-Scale Static WSNs T2 - 2024 34th International Telecommunication Networks and Applications Conference (ITNAC) Y1 - 2024 U6 - https://doi.org/10.1109/ITNAC62915.2024.10815368 SP - 1 EP - 6 PB - IEEE ER - TY - GEN A1 - Lyu, Yu-Xuan A1 - Fu, Qiang A1 - Wilczok, Dominika A1 - Ying, Kejun A1 - King, Aaron A1 - Antebi, Adam A1 - Vojta, Aleksandar A1 - Stolzing, Alexandra A1 - Moskalev, Alexey A1 - Georgievskaya, Anastasia A1 - Maier, Andrea B. A1 - Olsen, Andrea A1 - Groth, Anja A1 - Simon, Anna Katharina A1 - Brunet, Anne A1 - Jamil, Aisyah A1 - Kulaga, Anton A1 - Bhatti, Asif A1 - Yaden, Benjamin A1 - Pedersen, Bente Klarlund A1 - Schumacher, Björn A1 - Djordjevic, Boris A1 - Kennedy, Brian A1 - Chen, Chieh A1 - Huang, Christine Yuan A1 - Correll, Christoph U. A1 - Murphy, Coleen T. A1 - Ewald, Collin Y. A1 - Chen, Danica A1 - Valenzano, Dario Riccardo A1 - Sołdacki, Dariusz A1 - Erritzoe, David A1 - Meyer, David A1 - Sinclair, David A. A1 - Chini, Eduardo Nunes A1 - Teeling, Emma C. A1 - Morgen, Eric A1 - Verdin, Eric A1 - Vernet, Erik A1 - Pinilla, Estefano A1 - Fang, Evandro F. A1 - Bischof, Evelyne A1 - Mercken, Evi M. A1 - Finger, Fabian A1 - Kuipers, Folkert A1 - Pun, Frank W. A1 - Gyülveszi, Gabor A1 - Civiletto, Gabriele A1 - Zmudze, Garri A1 - Blander, Gil A1 - Pincus, Harold A. A1 - McClure, Joshua A1 - Kirkland, James L. A1 - Peyer, James A1 - Justice, Jamie N. A1 - Vijg, Jan A1 - Gruhn, Jennifer R. A1 - McLaughlin, Jerry A1 - Mannick, Joan A1 - Passos, João A1 - Baur, Joseph A. A1 - Betts-LaCroix, Joe A1 - Sedivy, John M. A1 - Speakman, John R. A1 - Shlain, Jordan A1 - Maltzahn, Julia von A1 - Andreasson, Katrin I. A1 - Moody, Kelsey A1 - Palikaras, Konstantinos A1 - Fortney, Kristen A1 - Niedernhofer, Laura J. A1 - Rasmussen, Lene Juel A1 - Veenhoff, Liesbeth M. A1 - Melton, Lisa A1 - Ferrucci, Luigi A1 - Quarta, Marco A1 - Koval, Maria A1 - Marinova, Maria A1 - Hamalainen, Mark A1 - Unfried, Maximilian A1 - Ringel, Michael S. A1 - Filipovic, Milos A1 - Topors, Mourad A1 - Mitin, Natalia A1 - Roy, Nawal A1 - Pintar, Nika A1 - Barzilai, Nir A1 - Binetti, Paolo A1 - Singh, Parminder A1 - Kohlhaas, Paul A1 - Robbins, Paul D. A1 - Rubin, Paul A1 - Fedichev, Peter O. A1 - Kamya, Petrina A1 - Muñoz-Canoves, Pura A1 - de Cabo, Rafael A1 - Faragher, Richard G. A. A1 - Konrad, Rob A1 - Ripa, Roberto A1 - Mansukhani, Robin A1 - Büttner, Sabrina A1 - Wickström, Sara A. A1 - Brunemeier, Sebastian A1 - Jakimov, Sergey A1 - Luo, Shan A1 - Rosenzweig-Lipson, Sharon A1 - Tsai, Shih-Yin A1 - Dimmeler, Stefanie A1 - Rando, Thomas A. A1 - Peterson, Tim R. A1 - Woods, Tina A1 - Wyss-Coray, Tony A1 - Finkel, Toren A1 - Strauss, Tzipora A1 - Gladyshev, Vadim N. A1 - Longo, Valter D. A1 - Dwaraka, Varun B. A1 - Gorbunova, Vera A1 - Acosta-Rodríguez, Victoria A. A1 - Sorrentino, Vincenzo A1 - Sebastiano, Vittorio A1 - Li, Wenbin A1 - Suh, Yousin A1 - Zhavoronkov, Alex A1 - Scheibye-Knudsen, Morten A1 - Bakula, Daniela T1 - Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity T2 - Aging Y1 - 2024 U6 - https://doi.org/10.18632/aging.206135 SN - 1945-4589 VL - 16 IS - 20 SP - 12955 EP - 12976 PB - Impact Journals, LLC ER - TY - GEN A1 - Haase, Elisabeth A1 - Lange, Toni A1 - Lützner, Jörg A1 - Kopkow, Christian A1 - Petzold, Thomas A1 - Günther, Klaus-Peter A1 - Schmitt, Jochen T1 - Indikation zur endoprothetischen Versorgung des Kniegelenks T2 - Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen Y1 - 2015 U6 - https://doi.org/10.1016/j.zefq.2015.09.029 SN - 1865-9217 SN - 2212-0289 VL - 109 IS - 8 SP - 605 EP - 614 ER - TY - GEN A1 - Schneider, Anna A1 - Hirsch, Florian A1 - Wechler, Klaus-Peter A1 - Raab, Alexandra A1 - Raab, Thomas T1 - Reconstruction of a Paleosurface and Archaeological Site Location in an Anthropogenic Drift Sand Area T2 - Archaeological Prospection N2 - Knowledge of the position of archaeological remains in the surface relief provides important basic information for archaeological survey design and interpretation. Geomorphological processes in (pre)history may have resulted in a modification of the local relief around archaeological sites, especially in areas that are prone to sediment erosion and relocation, such as sheet sand and dune landscapes. In this study, we reconstructed and analysed the palaeorelief of an archaeological excavation site in an inland dune area in southern Brandenburg, Germany. The remains of two Mesolithic sites were documented in the archaeological excavations and found to be associated with a buried soil horizon. To gather information on the relief of the buried soil surface, we used a combination of sedimentological and pedological profile descriptions along archaeological survey trenches and geophysical prospection with ground penetrating radar supplemented with microdrone photography and photogrammetry, global positioning system (GPS) surveys, and analysis of LiDAR-based elevation models. A digital elevation model of the buried surface was generated and analysed using a geographical information system (GIS). A comparison of the palaeosurface model with the recent surface elevation model shows that sand remobilization resulted in a considerable reshaping of the relief. Further, an analysis of the buried surface model shows that the relief position of the two archaeological sites in the study area was considerably more prominent in relation to the corresponding buried soil surface than in relation to the recent surface morphology. The results affirm the significance of Holocene sediment relocation for the local surface morphology and the importance of considering such relief modifications in archaeological surveys. Y1 - 2017 U6 - https://doi.org/10.1002/arp.1571 SN - 1099-0763 VL - 24 IS - 4 SP - 297 EP - 310 ER - TY - GEN A1 - Urban, Thomas A1 - Reinhardt, Fritjof A1 - Lohse, Peter A1 - Spitzer, Stefan G. A1 - Rasche, Luise A1 - Reichmann, Heinz T1 - Fatigue und sensomotorische Instabilität : neurologisch kontrollierte Konversion von Post-COVID-19- Patienten T1 - Fatigue and sensorimotor instability : neurologically controlled conversion of post-COVID-19 patients T2 - Der Nervenarzt : Organ der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde N2 - Hintergrund Für die Behandlung der Symptome des Post-COVID-19-Syndroms wird derzeit keine kausale Therapie nach evidenzbasierten Kriterien breit empfohlen. Die Evaluation der Veränderungen des Leitsymptoms Fatigue und der sensomotorischen Instabilität durch eine individualisierte beanspruchungsgesteuerte Trainingstherapie sowie durch eine intensivierte kognitive Verhaltenstherapie war das übergeordnete Ziel der Interventionsstudie über einen 3‑jährigen Zeitraum (Q1-2021 bis Q4-2023). Methodik Es wurden in den 3 Jahren im Post-COVID-19-Zentrum Lausitz (Senftenberg) 407 geimpfte nukleokapsidpositive Patienten behandelt. Bei 78 (rd. 19 %) von ihnen wurden als Leitsyndrome Fatigue/immunometabolische Depression und sensomotorische Instabilität konstatiert. Die Evaluation der individualisierten beanspruchungsgesteuerten Trainingstherapie erfolgte anhand der konkreten Post-COVID-19-Syndromatik und motorischer Fatigability-Parameter. Die sekundäre psychosomatische Syndromatik wurde mit kognitiven Fatigability-Parametern und mit Instrumenten der kognitiven Verhaltenstherapie bewertet. Die Untersuchung verhaltensbeeinflussender Parameter fand in Q2-2023 bis Q4-2023 mit einem leitfadengestützten qualitativen Interview unter den Therapieteilnehmern statt. Ergebnisse Die Post-COVID-19-Leitsymptomen „Fatigue“, „sensomotorische Instabilität“, „neuropsychiatrische Symptome“, „kardionale/autonome Dysfunktion“ und „Schmerzen“ verbesserten sich signifikant in der Gesamtkohorte sowie bei der geschlechtsspezifischen Analyse. Eine Verschlechterung trat bei „sekundären psychosomatischen Symptomen“ auf. Für alle motorischen Fatigability-Parameter konnte für die Gesamtkohorte mit dem Cohens d-Wert ein therapeutischer Effekt nachgewiesen werden. Positive Wirkungen erzielte eine Intensivierung der kognitiven Verhaltenstherapie durch eine zunehmende Entwicklung der Eigenaktivität der Patienten sowie deren Selbstkontrolle unter Einsatz von Persuasion und Gamification. N2 - Background For the treatment of the symptoms of post-COVID-19 syndrome, no causal therapy is currently widely recommended according to evidence-based criteria. The overarching goal of the intervention study over a 3-year period (Q1-2021–Q4-2023) was to evaluate the changes in the key symptoms of fatigue and sensorimotor instability through individualized stress-controlled training therapy and through intensified cognitive behavioral therapy. Material and methods In the 3‑year period 407 vaccinated nucleocapsid positive patients were treated at the Post-COVID-19 Center Lausitz (Senftenberg). In 78 (around 19%) fatigue/immunometabolic depression and sensorimotor instability were identified as the leading syndromes. The evaluation of the individualized stress-controlled training therapy was based on the specific post-COVID-19 syndrome and motor fatigue parameters. The secondary psychosomatic syndrome was assessed using cognitive fatigue parameters and cognitive behavioral therapy instruments. The investigation of -parameters influencing behavior took place in Q2-2023–Q4-2023 with a guide-supported qualitative interview among the participants. Results The post-COVID-19 key symptoms “fatigue,” “sensorimotor instability,” “neuropsychiatric symptoms,” “cardiac/autonomic dysfunction,” and “pain” improved significantly in the overall cohort and in the gender-specific analysis. A deterioration occurred in “secondary psychosomatic symptoms”. A therapeutic effect was demonstrated for all motor fatigue parameters for the entire cohort using the Cohen’s d value. An intensification of cognitive behavioral therapy achieved positive effects through an increasing development of the patients’ own activity and their self-control using persuasion and gamification. KW - Post-COVID-Syndrom KW - Fatigue KW - Sensomotorische Instabilität KW - Kognitive Verhaltenstherapie KW - Sekundäre psychosomatische Symptome KW - Post-COVID syndrome KW - Fatigue KW - Sensorimotor instability KW - Cognitive behavioral therapy KW - Secondary psychosomatic symptoms Y1 - 2024 U6 - https://doi.org/10.1007/s00115-024-01732-3 SN - 0028-2804 SN - 1433-0407 VL - 95 IS - 12 SP - 1104 EP - 1115 PB - Springer Medizin CY - Heidelberg ER - TY - GEN A1 - Roei, Tulchinsky A1 - Boris, Gilburd A1 - Yehuda, Shovman A1 - Milena, Tocut A1 - Eleanor, Zeruya A1 - Ariel, Binyaminov A1 - Tima, Davidson A1 - Büttner, Thomas A1 - Nasser, Abdullah A1 - Michel, Juliane A1 - Rödiger, Stefan A1 - Schierack, Peter A1 - Howard, Amital A1 - Roggenbuck, Dirk A1 - Yehuda, Shoenfeld A1 - Ora, Shovman T1 - CytoBead ANA 2 assay : a novel method for the detection of antinuclear antibodies T2 - Scientific reports N2 - Detection of anti-nuclear autoantibodies (ANA) is based on a two-step algorithm including indirect immunofluorescence (IIF) on HEp2 cells and subsequent reflex/confirmatory testing for specific autoantibodies. Simultaneous cell- and microbead-based autoantibody detection by IIF may be utilized for the evaluation of systemic autoimmune rheumatic diseases (SARDs). In the present study, we assessed the performance of CytoBead ANA 2 in the detection of ANA and ANA-specific autoantibodies, compared to ANA IIF and BioPlex™ 2200. We also tested the ability of CytoBead ANA DFS-70 to identify dense-fine speckled (DFS) pattern associated with anti-DFS70 antibodies in non-SARDs patients. Hundred-twelve routine sera samples were assessed by manual CytoBead ANA 2 for the presence of ANA and specific autoantibodies. In parallel, these samples were analyzed by HEp2 ANA IIF test and a subsequent multiplexed assay BioPlex™ 2200 ANA. Twenty-nine ANA-positive samples obtained from non-SARDs patients and exhibiting DFS pattern by ANA IIF were further tested by CytoBead ANA DFS-70. A substantial agreement was observed between classical ANA IIF and manual CytoBead ANA 2 for the detection of ANA (k = 0.74). Discordant results were mainly associated with the presence of anti-SSA/Ro antibodies detected by CytoBead ANA 2 in ANA IIF negative patients. A good to almost perfect agreement was found between CytoBead ANA 2 and BioPlex™ 2200 for detection of specific antibodies with kappa values ranging from 0.70 to 0.90. Twenty samples (68.9%) obtained from 29 ANA IIF positive without SARDs patients exhibited DFS pattern in CytoBead ANA DFS-70, which confirmed the presence of anti-DFS70 antibodies. The diagnostic performance of manual CytoBead ANA 2 for ANA screening and detection of ANA specific antibodies is comparable to the diagnostic performance of ANA IIF followed by BioPlex™ 2200. This novel one-step assay enables simultaneous ANA screening and confirmation and represents a promising alternative approach to the time-consuming and costly two-tier ANA analysis. KW - Anti-nuclear antibodies KW - Anti-DFS70 antibodies KW - Indirect immunofluorescence KW - Multiplexed assay KW - CytoBead technology Y1 - 2025 U6 - https://doi.org/10.1038/s41598-025-04583-3 SN - 2045-2322 VL - 15 IS - 1 SP - 1 EP - 11 PB - Nature Publishing Group UK CY - London ER - TY - GEN A1 - Sheppard, Jonathan P. A1 - Bohn Reckziegel, Rafael A1 - Borrass, Lars A1 - Chirwa, Paxie W. A1 - Cuaranhua, Claudio J. A1 - Hassler, Sibylle K A1 - Hoffmeister, Svenja A1 - Kestel, Florian A1 - Maier, Rebekka A1 - Mälicke, Mirko A1 - Morhart, Christopher A1 - Ndlovu, Nicholas P. A1 - Veste, Maik A1 - Funk, Roger A1 - Lang, Friedericke A1 - Seifert, Thomas A1 - du Toit, Ben A1 - Kahle, Hans-Peter T1 - Agroforestry: An Appropriate and Sustainable Response to a Changing Climate in Southern Africa? T2 - Sustainability N2 - Agroforestry is often discussed as a strategy that can be used both for the adaptation to and the mitigation of climate change effects. The climate of southern Africa is predicted to be severely affected by such changes. With agriculture noted as the continent’s largest economic sector, issues such as food security and land degradation are in the forefront. In the light of such concerns we review the current literature to investigate if agroforestry systems (AFS) are a suitable response to the challenges besetting traditional agricultural caused by a changing climate. The benefits bestowed by AFS are multiple, offering ecosystem services, influence over crop production and positive impacts on rural livelihoods through provisioning and income generation. Nevertheless, knowledge gaps remain. We identify outstanding questions requiring further investigation such as the interplay between trees and crops and their combination, with a discussion of potential benefits. Furthermore, we identify deficiencies in the institutional and policy frameworks that underlie the adoption and stimulus of AFS in the southern African region. We uphold the concept that AFS remains an appropriate and sustainable response for an increased resilience against a changing climate in southern Africa for the benefit of livelihoods and multiple environmental values KW - agroforestry KW - Southern Africa Y1 - 2020 UR - https://www.mdpi.com/2071-1050/12/17/6796 U6 - https://doi.org/10.3390/su12176796 VL - 12 IS - 17 ER - TY - GEN A1 - Hofer, Markus A1 - Lehmann, Peter A1 - Schneider, Anna A1 - Maurer, Thomas A1 - Stähli, Manfred A1 - Krafczyk, Manfred T1 - Modelling the emergence of surface erosion rills in an artificial catchment T2 - Structures and processes of the initial ecosystem development, 1st International Conference assoc. with 4th Meeting of Young Researchers in Earth Sciences (MYRES), 20-24 Sept. 2010, Cottbus, Germany Y1 - 2010 SP - S. 53 PB - BTU CY - Cottbus ER - TY - CHAP A1 - Hofer, Markus A1 - Lehmann, Peter A1 - Schneider, Anna A1 - Maurer, Thomas A1 - Stähli, Manfred A1 - Krafczyk, Manfred T1 - Modelling the emergence of surface erosion rills in an artificial catchment T2 - EGU General Assembly 2010, held in Vienna, Austria, 02 – 07 May 2010 Y1 - 2010 N1 - EGU2010-2498 PB - European Geophysical Society CY - Katlenburg-Lindau ER - TY - GEN A1 - Dietrich, Lucas A1 - Förster, Benjamin A1 - Langendörfer, Peter A1 - Hinze, Thomas T1 - A visual discrete event-based simulator for protection of plants against herbivores employed as computational optimization game N2 - Plants come with sophisticated strategies to survive within a highly competing environment. In addition, they need to resist frequent attacks from a variety of herbivores acting alone, in small groups, or in swarms. Since the amount of energy a plant might invest in defense and reproduction is limited, a complex optimization problem emerges. In a shared habitat, plants fight herbivores by shape and camouflage, by the release of specific toxins, or by attracting predators of herbivores. Furthermore, plants alert their surrounding field by signaling substances in the event of an assault. Transported by air or through a network of roots, signaling substances reach neighbors to trigger their defense. The offsprings of a plant commonly grow within a certain distance to benefit from symbiotic protection. We introduce a grid-based visual simulation software for detailed configuration and subsequent processing of the behavior of the resulting system in time and space. In terms of solution to a computational optimization problem inspired by nature, settings with low energy need and long life able to cope with different patterns of attack can be figured out and analyzed. Applications include novel techniques for efficient construction and secure operation of sensor networks. KW - Plant defense KW - Event-based simulation KW - Topological optimization Y1 - 2025 U6 - https://doi.org/10.48550/arXiv.2509.15787 SP - 1 EP - 25 PB - arXiv ER - TY - GEN A1 - Sovová, Lucie A1 - Cima, Ottavia A1 - Jehlička, Petr A1 - Pungas, Lilian A1 - Sattler, Markus A1 - Smith, Thomas S.J. A1 - Decker, Anja A1 - Johanisova, Nadia A1 - Kovanen, Sunna A1 - North, Peter T1 - On Babushkas and postcapitalism : theorising diverse economies from the Global East T2 - Antipode : a radical journal of geography N2 - As transformative visions for more just and sustainable societies multiply around the globe, the Diverse and Community Economies approach presents one of the most influential strategies to advance postcapitalist visions. In this paper, we contribute to this project based on our research and activism in the Global East, intended here as Central and Eastern Europe and the former Soviet Union. We argue that engaging with the Global East is not only a matter of epistemic inclusivity but also a (too‐often‐neglected) opportunity to learn from a region with a history of dramatic economic transformation and diversity. We highlight examples of community economies already contributing to more‐than‐human wellbeing, and we present emerging theoretical insights concerning temporality, the multi‐sitedness of the enterprise, and diverse economic subjectivities. With that, we articulate our ongoing research agenda and advance conversations with postcapitalist scholarship and politics. KW - Global East KW - Diverse economies KW - Epistemic inclusivity KW - Postcapitalist politics KW - Community economies KW - Postsocialism Y1 - 2025 U6 - https://doi.org/10.1111/anti.70034 SN - 0066-4812 SN - 1467-8330 VL - 57 IS - 6 SP - 2484 EP - 2507 PB - Wiley CY - Hoboken, NJ ER -