TY - GEN A1 - Wilczek, Sebastian A1 - Schulze, Julian A1 - Brinkmann, Ralf Peter A1 - Donkó, Zoltan A1 - Trieschmann, Jan A1 - Mussenbrock, Thomas T1 - Electron dynamics in low pressure capacitively coupled radio frequency discharges T2 - Journal of Applied Physics Y1 - 2020 U6 - https://doi.org/10.1063/5.0003114.1 VL - 127 IS - 18 ER - TY - GEN A1 - Schöberl, Florian A1 - Pradhan, Cauchy A1 - Irving, Stephanie A1 - Buerger, Katharina A1 - Xiong, Guoming A1 - Kugler, Günter A1 - Kohlbecher, Stefan A1 - Engmann, Julia A1 - Werner, Philipp A1 - Brendel, Matthias A1 - Schneider, Erich A1 - Perneczky, Robert A1 - Jahn, Klaus A1 - Fougère, Christian la A1 - Bartenstein, Peter A1 - Brandt, Thomas A1 - Dietrich, Marianne A1 - Zwergal, Andreas T1 - Real-space navigation testing differentiates between amyloid-positive and -negative aMCI T2 - Neurology : official journal of the American Academy of Neurology Y1 - 2020 UR - https://n.neurology.org/content/94/8/e861 U6 - https://doi.org/10.1212/WNL.0000000000008758 SN - 1526-632X VL - 94 IS - 8 SP - e861 EP - e873 ER - TY - GEN A1 - Schöberl, Florian A1 - Irving, Stephanie A1 - Pradhan, Cauchy A1 - Bardins, Stanislav A1 - Trapp, Christoph A1 - Schneider, Erich A1 - Kugler, Günter A1 - Bartenstein, Peter A1 - Dietrich, Marianne A1 - Brandt, Thomas A1 - Zwergal, Andreas T1 - Prolonged allocentric navigation deficits indicate hippocampal damage in TGA T2 - Neurology : official journal of the American Academy of Neurology N2 - Objective To investigate long-term recovery of allocentric and egocentric spatial orientation as a sensitive marker for hippocampal and extrahippocampal network function in transient global amnesia (TGA). Methods A group of 18 patients with TGA performed an established real-space navigation paradigm, requiring allo- and egocentric spatial orientation abilities, 3 days (postacute stage) and 3 months (follow-up) after symptom onset. Visual exploration behavior and navigation strategy were documented by a gaze-controlled, head-fixed camera. Allo- and egocentric spatial orientation performance was compared to that of 12 age-matched healthy controls. Navigation-induced brain activations were measured using [18F]-fluorodeoxyglucose-PET in a subgroup of 8 patients in the postacute stage and compared to those of the controls. Results In the postacute stage, the patients navigated worse and had higher error rates than controls in allocentric (p = 0.002), but not in egocentric, route planning (p = 0.30), despite complete recovery of verbal (p = 0.58) and figural memory (p = 0.11). Until follow-up, allocentric navigation deficits improved, but higher error rates and reduced use of shortcuts persisted (p < 0.0001). Patients still exhibited relatively more fixations of unique landmarks during follow-up (p = 0.05). PET measurements during the postacute stage showed increased navigation-induced brain activations in the right hippocampus, bilateral retrosplenial, parietal, and mesiofrontal cortices, and cerebellar dentate nucleus in patients compared to controls (p < 0.005). Conclusions Patients with TGA show selective and prolonged deficits of allocentric spatial orientation. Activations in right hippocampal and extrahippocampal hubs of the cerebral navigation network functionally substitute for the deficit in creating and updating the internal cognitive map in TGA. Y1 - 2019 UR - https://n.neurology.org/content/92/3/e234/tab-article-info U6 - https://doi.org/10.1212/WNL.0000000000006779 SN - 0028-3878 SN - 1526-632X VL - 92 IS - 3 SP - e234 EP - e243 ER - TY - GEN A1 - Jurischka, Christoph A1 - Dinter, Franziska A1 - Efimova, Anastasia A1 - Weiss, Romano A1 - Schiebel, Juliane A1 - Schulz, Christian A1 - Fayziev, Bekzodjon A1 - Schierack, Peter A1 - Fischer, Thomas A1 - Rödiger, Stefan T1 - An explorative study of polymers for 3D printing of bioanalytical test systems T2 - Clinical Hemorheology and Microcirculation N2 - Background: The 3D printing is relevant as a manufacturing technology of functional models for forensic, pharmaceutical and bioanalytical applications such as drug delivery systems, sample preparation and point-of-care tests. Objective: Melting behavior and autofluorescence of materials are decisive for optimal printing and applicability of the product which are influenced by varying unknown additives. Methods: We have produced devices for bioanalytical applications from commercially available thermoplastic polymers using a melt-layer process. We characterized them by differential scanning calorimetry, fluorescence spectroscopy and functional assays (DNA capture assay, model for cell adhesion, bacterial adhesion and biofilm formation test). Results: From 14 tested colored, transparent and black materials we found only deep black acrylonitrile-butadiene-styrene (ABS) and some black polylactic acid (PLA) useable for fluorescence-based assays, with low autofluorescence only in the short-wave range of 300-400 nm. PLA was suitable for standard bioanalytical purposes due to a glass transition temperature of approximately 60°C, resistance to common laboratory chemicals and easy print processing. For temperature-critical methods, such as hybridization reactions up to 90°C, ABS was better suited. Conclusions: Autofluorescence was not a disadvantage per se but can also be used as a reference signal in assays. The rapid development of individual protocols for sample processing and analysis required the availability of a material with consistent quality over time. For fluorescence-based assays, the use of commercial standard materials did not seem to meet this requirement. KW - Thermal analysis KW - 3D Printing Y1 - 2020 UR - https://pubmed.ncbi.nlm.nih.gov/31929149/ U6 - https://doi.org/10.3233/CH-190713 SN - 1875-8622 VL - 75 IS - 1 SP - 57 EP - 84 ER - TY - GEN A1 - Klich, Maximilian A1 - Wilczek, Sebastian A1 - Janssen, Jesper Frederikus Jacobus A1 - Brinkmann, Ralf Peter A1 - Mussenbrock, Thomas A1 - Trieschmann, Jan T1 - Ion dynamics in capacitively coupled argon–xenon discharges T2 - Plasma Sources Science and Technology Y1 - 2021 U6 - https://doi.org/10.1088/1361-6595/ac02b0 SN - 1361-6595 VL - 30 IS - 6 ER - TY - GEN A1 - Schröder, Lena A1 - Werder, Dina von A1 - Ramaioli, Cecilia A1 - Wachtler, Thomas A1 - Henningsen, Peter A1 - Glasauer, Stefan A1 - Lehnen, Nadine T1 - Unstable Gaze in Functional Dizziness: A Contribution to Understanding the Pathophysiology of Functional Disorders T2 - Frontiers in Neuroscience N2 - Objective: We are still lacking a pathophysiological mechanism for functional disorders explaining the emergence and manifestation of characteristic, severely impairing bodily symptoms like chest pain or dizziness. A recent hypothesis based on the predictive coding theory of brain function suggests that in functional disorders, internal expectations do not match the actual sensory body states, leading to perceptual dysregulation and symptom perception. To test this hypothesis, we investigated the account of internal expectations and sensory input on gaze stabilization, a physiologically relevant parameter of gaze shifts, in functional dizziness. Methods: We assessed gaze stabilization in eight functional dizziness patients and 11 healthy controls during two distinct epochs of large gaze shifts: during a counter- rotation epoch (CR epoch), where the brain can use internal models, motor planning, and resulting internal expectations to achieve internally driven gaze stabilization; and during an oscillation epoch (OSC epoch), where, due to terminated motor planning, no movement expectations are present, and gaze is stabilized by sensory input alone. Results: Gaze stabilization differed between functional patients and healthy controls only when internal movement expectations were involved [F(1,17) = 14.63, p = 0.001, and partial η2 = 0.463]: functional dizziness patients showed reduced gaze stabilization during the CR (p = 0.036) but not OSC epoch (p = 0.26). Conclusion: While sensory-driven gaze stabilization is intact, there are marked, well- measurable deficits in internally-driven gaze stabilization in functional dizziness pointing at internal expectations that do not match actual body states. This experimental evidence supports the perceptual dysregulation hypothesis of functional disorders and is an important step toward understanding the underlying pathophysiology. Y1 - 2021 U6 - https://doi.org/10.3389/fnins.2021.685590 SN - 1662-453X SN - 1662-4548 VL - 15 ER - TY - GEN A1 - Schmidt, Carsten A1 - Borcherding, Heike A1 - Thiele, Thomas A1 - Schedler, Uwe A1 - Werner, Franziska A1 - Rödiger, Stefan A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - Fluorescence-encoded poly (methyl metharcylate) nanoparticles for a lateral flow assay detecting IgM autoantibodies in rheumatoid arthritis T2 - Analytical biochemistry Y1 - 2021 U6 - https://doi.org/10.1016/journal.ppat.1010118 SN - 1096-0309 VL - Vol. 633 ER - TY - GEN A1 - Emmenegger, Marc A1 - Kumar, Sreedhar Saseendran A1 - Emmenegger, Vishalini A1 - Malinauskas, Tomas A1 - Büttner, Thomas A1 - Rose, Laura A1 - Schierack, Peter A1 - Sprinzl, Martin F. A1 - Sommer, Clemens J. A1 - Lackner, Karl J. A1 - Aguzzi, Adriano A1 - Roggenbuck, Dirk A1 - Frauenknecht, Katrin B. M. T1 - Anti-prothrombin autoantibodies enriched after infection with SARS-CoV-2 and influenced by strength of antibody response against SARS-CoV-2 proteins T2 - PLoS pathogens Y1 - 2021 U6 - https://doi.org/10.1371/journal.ppat.1010118 SN - 1553-7374 VL - 17 IS - 12 ER - TY - GEN A1 - Uchino, Kazuki A1 - Raab, Alexandra A1 - Bonhage, Alexander A1 - Schneider, Anna A1 - Raab, Thomas A1 - Wechler, Klaus-Peter A1 - Bauriegel, Albrecht T1 - Spatial heterogeneity of buried and recent soils in a drift sand area in North-Eastern Germany T2 - EGU General Assembly 2022, Vienna, Austria, 23–27 May 2022 N2 - In the North European Lowland, on the sandy deposits of the Weichselian glaciation, soils developed during periods of landscape stability are often conserved under windblown sand. However, small-scale changes of sediments and other soil forming factors can result in high spatial variation of soil properties in these landscapes; and relocation of soil material by geomorphic processes further increases the spatial heterogeneity of the soil landscape. These spatial variations in soil properties and conservation need to be considered in order to correctly decipher and interpret the buried soils as records of past environmental conditions. In the forefield of the open-cast mine Cottbus-Nord, archaeological excavations in a dune and drift sand area revealed widespread buried soils of different characteristics. The densely spaced excavation trenches give exceptionally good insights into the pedosphere, allow for reconstructing the distribution of fossil and recent soils in a high spatial resolution, and offer good opportunities to improve the understanding of spatial and temporal patterns of soil formation. Remains of postpleistocene hunter-gatherer campsites were documented in archaeological excavations and found to be associated with a buried soil horizon. We recorded the stratigraphy of soil profiles along more than 15 trenches within an area of about 20 ha, and additionally described the position of buried soils from GPR surveys and microdrone photogrammetry. In a recently opened, 455 m long trench, all characteristic soils and sediments of the study region could be observed and stratigraphically connected. Within this trench, four profiles were identified for further research. Each profile was classified and described according to WRB and German Guidelines for Soil Mapping; and was sampled and investigated through laboratory analyses including determination of organic matter, total carbon and nitrogen contents, soil colour identification, texture analysis, magnetic susceptibility measurement, metal content analysis using X-ray fluorescence analyzer and pH measurement. The compaction and cementation of soil horizons was assessed in situ with a pocket penetrometer. Results show a small-scale mosaic of soils developed on fluvio-aeolian, limnic and aeolian sediments, high spatial variations in pedogenesis due to varying groundwater influence and intensity of horizontal and vertical leachate transport, and high variations in the erosion or conservation of fossil soils. The soil and sediment stratigraphy reflects several phases of landscape development: i) the formation of a Late Pleistocene soil on fluvio-aeolian deposits, ii) a fossilization by aeolian sands, iii) a stability phase with intensive podsolization and peat formation, and iv) a land use-induced aeolian remobilization of the sands. Y1 - 2022 U6 - https://doi.org/10.5194/egusphere-egu22-2354 ER - TY - GEN A1 - Klimczak, Peter A1 - Halamuda, Thomas T1 - Twitter-Studie: Zeitungen als (Hidden) Champions auf Twitter T2 - BDZV-Jahresreport DIGITAL N2 - Zeitungen gehören zu den Leitmedien auf der Diskursplattform Twitter. Sie versorgen die Community mit tagesaktuellem Content und mischen auch im Diskurs mit. Insbesondere Letzteres bringt jedoch nicht nur Vor-, sondern auch Nachteile. KW - Zeitungen KW - Leitmedien KW - Twitter KW - Massenmedien KW - Tweets Y1 - 2022 UR - https://www.halamuda.com/wp-content/uploads/2022/07/BDZV_Jahresreport_Digital_2022-Zeitungen-auf-Twitter.pdf VL - 2022 SP - 152 EP - 156 ER - TY - GEN A1 - Förster, Benjamin A1 - Langendörfer, Peter A1 - Hinze, Thomas T1 - Novel Approach to a Plant Inspired Distributed Security Scheme for Wireless Sensor Networks T2 - 12th Mediterranean Conference on Embedded Computing (MECO), Budva, Montenegro, 2023 N2 - Energy efficiency is a key factor for the longevity of wireless sensor networks (WSNs). Most representatives of the plants have evolved to be highly energy-efficient in their survival strategies, despite their limited resources. Plants have to deal with a variety of threats originating from different herbivores and microbial pathogens while handling a number of abiotic stress factors. For plants and WSNs, different defence mechanisms impose different fitness costs and therefore the costs and benefits have to be well-balanced. This way, plants are able to not only conquer a large variety of different attacks but also handle several different simultaneous attacks adequately. To react early and adapt to upcoming threats, plants within a network are capable of signalling each other within a certain distance about ongoing attacks. The biological strategies of plants in terms of signalling and defence, as well as their energy and resource limitations, share significant similarities with WSNs. This study aims to explore these similarities and demonstrates the correspondence between the biological concepts and WSNs. Additionally, we present a novel approach to enhancing security in WSNs through a cooperative distributed security scheme inspired by key factors of plant defence mechanisms, with the goal of reducing the energy constraints and maximising the longevity of the network. KW - Wireless sensor networks KW - Pathogens KW - Embedded computing KW - Cyber-physical systems Y1 - 2023 SN - 979-8-3503-2291-0 SN - 979-8-3503-2290-3 U6 - https://doi.org/10.1109/MECO58584.2023.10154949 SN - 2637-9511 ER - TY - GEN A1 - Förster, Benjamin A1 - Langendörfer, Peter A1 - Hinze, Thomas T1 - Determining Distributions of Security Means for Wireless Sensor Networks based on the Model of a Neighbourhood Watch T2 - arXiv N2 - Neighbourhood watch is a concept that allows a community to distribute a complex security task in between all members. Members of the community carry out individual security tasks to contribute to the overall security of it. It reduces the workload of a particular individual while securing all members and allowing them to carry out a multitude of security tasks. Wireless sensor networks (WSNs) are composed of resource-constraint independent battery driven computers as nodes communicating wirelessly. Security in WSNs is essential. Without sufficient security, an attacker is able to eavesdrop the communication, tamper monitoring results or deny critical nodes providing their service in a way to cut off larger network parts. The resource-constraint nature of sensor nodes prevents them from running full-fledged security protocols. Instead, it is necessary to assess the most significant security threats and implement specialised protocols. A neighbourhood-watch inspired distributed security scheme for WSNs has been introduced by Langend\"orfer. Its goal is to increase the variety of attacks a WSN can fend off. A framework of such complexity has to be designed in multiple steps. Here, we introduce an approach to determine distributions of security means on large-scale static homogeneous WSNs. Therefore, we model WSNs as undirected graphs in which two nodes connected iff they are in transmission range. The framework aims to partition the graph into $n$ distinct security means resulting in the targeted distribution. The underlying problems turn out to be NP hard and we attempt to solve them using linear programs (LPs). To evaluate the computability of the LPs, we generate large numbers of random {\lambda}-precision unit disk graphs (UDGs) as representation of WSNs. For this purpose, we introduce a novel {\lambda}-precision UDG generator to model WSNs with a minimal distance in between nodes. Y1 - 2023 U6 - https://doi.org/10.48550/arXiv.2212.09050 ER - TY - GEN A1 - Förster, Benjamin A1 - Langendörfer, Peter A1 - Hinze, Thomas T1 - Determining Distributions of Security Means for WSNs Based on the Model of a Neighborhood Watch T2 - IEEE Access Y1 - 2024 U6 - https://doi.org/10.1109/ACCESS.2024.3404816 SN - 2169-3536 VL - 12 SP - 74343 EP - 74366 PB - Institute of Electrical and Electronics Engineers (IEEE) ER - TY - GEN A1 - Förster, Benjamin A1 - Langendörfer, Peter A1 - Hinze, Thomas T1 - Security mean distribution in WSNs for cooperative schemes T2 - Vorträge : iCCC2024 - iCampµs Cottbus Conference 2024-05-14 - 2024-05-16 Cottbus Y1 - 2024 U6 - https://doi.org/10.5162/iCCC2024/1.2 SP - 38 EP - 41 PB - AMA Service GmbH CY - Von-Münchhausen-Str. 49, 31515 Wunstorf, Germany ER - TY - GEN A1 - Becker, L. A1 - Storck, Peter A1 - Liu, Y. A1 - Schwalb, G. A1 - Schroeder, Thomas A1 - Fischer, Inga Anita A1 - Albrecht, M. T1 - Optimizing misfit dislocation glide kinetics for enhanced threading dislocation density reduction in Si1− xGex/Si (001) layers through dynamic growth rate control T2 - Journal of Applied Physics Y1 - 2024 U6 - https://doi.org/10.1063/5.0204318 SN - 0021-8979 SN - 1089-7550 VL - 135 IS - 20 SP - 10 ER - TY - GEN A1 - Martre, Pierre A1 - Dueri, Sibylle A1 - Guarin, Jose Rafael A1 - Ewert, Frank A1 - Webber, Heidi A1 - Calderini, Daniel A1 - Molero, Gemma A1 - Reynolds, Matthew A1 - Miralles, Daniel A1 - Garcia, Guillermo A1 - Brown, Hamish A1 - George, Mike A1 - Craigie, Rob A1 - Cohan, Jean‐Pierre A1 - Deswarte, Jean-Charles A1 - Slafer, Gustavo A. A1 - Giunta, Francesco A1 - Cammarano, Davide A1 - Ferrise, Roberto A1 - Gaiser, Thomas A1 - Gao, Yujing A1 - Hochman, Zvi A1 - Hoogenboom, Gerrit A1 - Hunt, Leslie A. A1 - Kersebaum, Kurt C. A1 - Nendel, Claas A1 - Padovan, Gloria A1 - Ruane, Alex C. A1 - Srivastava, Amit Kumar A1 - Stella, Tommaso A1 - Supit, Iwan A1 - Thorburn, Peter A1 - Wang, Enli A1 - Wolf, Joost A1 - Zhao, Chuang A1 - Zhao, Zhigan A1 - Asseng, Senthold T1 - Global needs for nitrogen fertilizer to improve wheat yield under climate change T2 - Nature Plants Y1 - 2024 U6 - https://doi.org/10.1038/s41477-024-01739-3 SN - 2055-0278 VL - 10 IS - 7 SP - 1081 EP - 1090 PB - Springer Science and Business Media LLC ER - TY - GEN A1 - Martre, Pierre A1 - Dueri, Sibylle A1 - Brown, Hamish A1 - Asseng, Senthold A1 - Ewert, Frank A1 - Webber, Heidi A1 - George, Mike A1 - Craigie, Rob A1 - Guarin, Jose Rafael A1 - Pequeno, Diego A1 - Stella, Tommaso A1 - Ahmed, Mukhtar A1 - Alderman, Phillip A1 - Basso, Bruno A1 - Berger, Andres A1 - Bracho Mujica, Gennady A1 - Cammarano, Davide A1 - Chen, Yi A1 - Dumont, Benjamin A1 - Rezaei, Ehsan Eyshi A1 - Fereres, Elias A1 - Ferrise, Roberto A1 - Gaiser, Thomas A1 - Gao, Yujing A1 - Garcia-Vila, Margarita A1 - Gayler, Sebastian A1 - Hochman, Zvi A1 - Hoogenboom, Gerrit A1 - Kersebaum, Kurt C. A1 - Nendel, Claas A1 - Olesen, Jørgen A1 - Padovan, Gloria A1 - Palosuo, Taru A1 - Priesack, Eckart A1 - Pullens, Johannes A1 - Rodríguez, Alfredo A1 - Rötter, Reimund P. A1 - Ruiz Ramos, Margarita A1 - Semenov, Mikhail A1 - Senapati, Nimai A1 - Siebert, Stefan A1 - Srivastava, Amit Kumar A1 - Stöckle, Claudio A1 - Supit, Iwan A1 - Tao, Fulu A1 - Thorburn, Peter A1 - Wang, Enli A1 - Weber, Tobias A1 - Xiao, Liujun A1 - Zhao, Chuang A1 - Zhao, Jin A1 - Zhao, Zhigan A1 - Zhu, Yan T1 - Winter wheat experiments to optimize sowing dates and densities in a high-yielding environment in New Zealand: field experiments and AgMIP-Wheat multi-model simulations T2 - Open Data Journal for Agricultural Research N2 - This paper describes the data set that was used to test the accuracy of twenty-nine crop models in simulating the effect of changing sowing dates and sowing densities on wheat productivity for a high-yielding environment in New Zealand. The data includes one winter wheat cultivar (Wakanui) grown during six consecutive years, from 2012-2013 to 2017-2018, at two farms located in Leeston and Wakanui in Canterbury, New Zealand. The simulations were carried out in the framework of the Agricultural Model Intercomparison and Improvement Project for wheat (AgMIP-Wheat). Data include local daily weather data, soil profile characteristics and initial conditions, crop measurements at maturity (grain, stem, chaff and leaf dry weight, ear number and grain number, grain unit dry weight), and at stem elongation and anthesis (total above ground dry biomass, leaf number per stem and leaf area index). Several in-season measurements of the normalized difference vegetation index (NDVI) and the fraction of intercepted photosynthetically active radiation (FIPAR) are also available. The crop model simulations include both daily in-season and end-of-season results from twenty-nine wheat models. KW - field experimental data KW - multi-crop model ensemble KW - sowing date KW - sowing density KW - winter wheat KW - yield potential Y1 - 2024 U6 - https://doi.org/10.18174/odjar.v10i0.18442 SN - 2352-6378 VL - 10 SP - 14 EP - 21 PB - Wageningen University and Research ER - TY - GEN A1 - Boetzl, Fabian A1 - Sponsler, Douglas A1 - Albrecht, Matthias A1 - Batáry, Péter A1 - Birkhofer, Klaus A1 - Knapp, Michal A1 - Krauss, Jochen A1 - Maas, Bea A1 - Martin, Emily A. A1 - Sirami, Clélia A1 - Sutter, Louis A1 - Bertrand, Colette A1 - Baillod, Aliette A1 - Bota, Gerard A1 - Bretagnolle, Vincent A1 - Brotons, Lluís A1 - Frank, Thomas A1 - Fusser, Moritz A1 - Giralt, David A1 - González, Ezequiel A1 - Hof, Anouschka A1 - Luka, Henryk A1 - Marrec, Ronan A1 - Nash, Michael A1 - Ng, Katherina A1 - Plantegenest, Manuel A1 - Poulin, Brigitte A1 - Siriwardena, Gavin A1 - Zubair-Anjum, Muhammad A1 - Entling, Martin A1 - Steffan-Dewenter, Ingolf A1 - Schirmel, Jens T1 - Distance functions of carabids in crop fields depend on functional traits, crop type and adjacent habitat: a synthesis T2 - Proceedings Royal Society. Series B, Biological sciences Y1 - 2024 U6 - https://doi.org/10.1098/rspb.2023.2383 SN - 1471-2954 VL - Vol. 291 SP - 1 EP - 10 ER - TY - GEN A1 - Förster, Benjamin A1 - Hinze, Thomas A1 - Langendorfer, Peter T1 - Topology- and Resource-Based Distribution Scheme for Collaborative Security-Focused Design Space Exploration in Large-Scale Static WSNs T2 - 2024 34th International Telecommunication Networks and Applications Conference (ITNAC) Y1 - 2024 U6 - https://doi.org/10.1109/ITNAC62915.2024.10815368 SP - 1 EP - 6 PB - IEEE ER - TY - GEN A1 - Lyu, Yu-Xuan A1 - Fu, Qiang A1 - Wilczok, Dominika A1 - Ying, Kejun A1 - King, Aaron A1 - Antebi, Adam A1 - Vojta, Aleksandar A1 - Stolzing, Alexandra A1 - Moskalev, Alexey A1 - Georgievskaya, Anastasia A1 - Maier, Andrea B. A1 - Olsen, Andrea A1 - Groth, Anja A1 - Simon, Anna Katharina A1 - Brunet, Anne A1 - Jamil, Aisyah A1 - Kulaga, Anton A1 - Bhatti, Asif A1 - Yaden, Benjamin A1 - Pedersen, Bente Klarlund A1 - Schumacher, Björn A1 - Djordjevic, Boris A1 - Kennedy, Brian A1 - Chen, Chieh A1 - Huang, Christine Yuan A1 - Correll, Christoph U. A1 - Murphy, Coleen T. A1 - Ewald, Collin Y. A1 - Chen, Danica A1 - Valenzano, Dario Riccardo A1 - Sołdacki, Dariusz A1 - Erritzoe, David A1 - Meyer, David A1 - Sinclair, David A. A1 - Chini, Eduardo Nunes A1 - Teeling, Emma C. A1 - Morgen, Eric A1 - Verdin, Eric A1 - Vernet, Erik A1 - Pinilla, Estefano A1 - Fang, Evandro F. A1 - Bischof, Evelyne A1 - Mercken, Evi M. A1 - Finger, Fabian A1 - Kuipers, Folkert A1 - Pun, Frank W. A1 - Gyülveszi, Gabor A1 - Civiletto, Gabriele A1 - Zmudze, Garri A1 - Blander, Gil A1 - Pincus, Harold A. A1 - McClure, Joshua A1 - Kirkland, James L. A1 - Peyer, James A1 - Justice, Jamie N. A1 - Vijg, Jan A1 - Gruhn, Jennifer R. A1 - McLaughlin, Jerry A1 - Mannick, Joan A1 - Passos, João A1 - Baur, Joseph A. A1 - Betts-LaCroix, Joe A1 - Sedivy, John M. A1 - Speakman, John R. A1 - Shlain, Jordan A1 - Maltzahn, Julia von A1 - Andreasson, Katrin I. A1 - Moody, Kelsey A1 - Palikaras, Konstantinos A1 - Fortney, Kristen A1 - Niedernhofer, Laura J. A1 - Rasmussen, Lene Juel A1 - Veenhoff, Liesbeth M. A1 - Melton, Lisa A1 - Ferrucci, Luigi A1 - Quarta, Marco A1 - Koval, Maria A1 - Marinova, Maria A1 - Hamalainen, Mark A1 - Unfried, Maximilian A1 - Ringel, Michael S. A1 - Filipovic, Milos A1 - Topors, Mourad A1 - Mitin, Natalia A1 - Roy, Nawal A1 - Pintar, Nika A1 - Barzilai, Nir A1 - Binetti, Paolo A1 - Singh, Parminder A1 - Kohlhaas, Paul A1 - Robbins, Paul D. A1 - Rubin, Paul A1 - Fedichev, Peter O. A1 - Kamya, Petrina A1 - Muñoz-Canoves, Pura A1 - de Cabo, Rafael A1 - Faragher, Richard G. A. A1 - Konrad, Rob A1 - Ripa, Roberto A1 - Mansukhani, Robin A1 - Büttner, Sabrina A1 - Wickström, Sara A. A1 - Brunemeier, Sebastian A1 - Jakimov, Sergey A1 - Luo, Shan A1 - Rosenzweig-Lipson, Sharon A1 - Tsai, Shih-Yin A1 - Dimmeler, Stefanie A1 - Rando, Thomas A. A1 - Peterson, Tim R. A1 - Woods, Tina A1 - Wyss-Coray, Tony A1 - Finkel, Toren A1 - Strauss, Tzipora A1 - Gladyshev, Vadim N. A1 - Longo, Valter D. A1 - Dwaraka, Varun B. A1 - Gorbunova, Vera A1 - Acosta-Rodríguez, Victoria A. A1 - Sorrentino, Vincenzo A1 - Sebastiano, Vittorio A1 - Li, Wenbin A1 - Suh, Yousin A1 - Zhavoronkov, Alex A1 - Scheibye-Knudsen, Morten A1 - Bakula, Daniela T1 - Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity T2 - Aging Y1 - 2024 U6 - https://doi.org/10.18632/aging.206135 SN - 1945-4589 VL - 16 IS - 20 SP - 12955 EP - 12976 PB - Impact Journals, LLC ER - TY - GEN A1 - Haase, Elisabeth A1 - Lange, Toni A1 - Lützner, Jörg A1 - Kopkow, Christian A1 - Petzold, Thomas A1 - Günther, Klaus-Peter A1 - Schmitt, Jochen T1 - Indikation zur endoprothetischen Versorgung des Kniegelenks T2 - Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen Y1 - 2015 U6 - https://doi.org/10.1016/j.zefq.2015.09.029 SN - 1865-9217 SN - 2212-0289 VL - 109 IS - 8 SP - 605 EP - 614 ER - TY - GEN A1 - Schneider, Anna A1 - Hirsch, Florian A1 - Wechler, Klaus-Peter A1 - Raab, Alexandra A1 - Raab, Thomas T1 - Reconstruction of a Paleosurface and Archaeological Site Location in an Anthropogenic Drift Sand Area T2 - Archaeological Prospection N2 - Knowledge of the position of archaeological remains in the surface relief provides important basic information for archaeological survey design and interpretation. Geomorphological processes in (pre)history may have resulted in a modification of the local relief around archaeological sites, especially in areas that are prone to sediment erosion and relocation, such as sheet sand and dune landscapes. In this study, we reconstructed and analysed the palaeorelief of an archaeological excavation site in an inland dune area in southern Brandenburg, Germany. The remains of two Mesolithic sites were documented in the archaeological excavations and found to be associated with a buried soil horizon. To gather information on the relief of the buried soil surface, we used a combination of sedimentological and pedological profile descriptions along archaeological survey trenches and geophysical prospection with ground penetrating radar supplemented with microdrone photography and photogrammetry, global positioning system (GPS) surveys, and analysis of LiDAR-based elevation models. A digital elevation model of the buried surface was generated and analysed using a geographical information system (GIS). A comparison of the palaeosurface model with the recent surface elevation model shows that sand remobilization resulted in a considerable reshaping of the relief. Further, an analysis of the buried surface model shows that the relief position of the two archaeological sites in the study area was considerably more prominent in relation to the corresponding buried soil surface than in relation to the recent surface morphology. The results affirm the significance of Holocene sediment relocation for the local surface morphology and the importance of considering such relief modifications in archaeological surveys. Y1 - 2017 U6 - https://doi.org/10.1002/arp.1571 SN - 1099-0763 VL - 24 IS - 4 SP - 297 EP - 310 ER - TY - GEN A1 - Urban, Thomas A1 - Reinhardt, Fritjof A1 - Lohse, Peter A1 - Spitzer, Stefan G. A1 - Rasche, Luise A1 - Reichmann, Heinz T1 - Fatigue und sensomotorische Instabilität : neurologisch kontrollierte Konversion von Post-COVID-19- Patienten T1 - Fatigue and sensorimotor instability : neurologically controlled conversion of post-COVID-19 patients T2 - Der Nervenarzt : Organ der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde N2 - Hintergrund Für die Behandlung der Symptome des Post-COVID-19-Syndroms wird derzeit keine kausale Therapie nach evidenzbasierten Kriterien breit empfohlen. Die Evaluation der Veränderungen des Leitsymptoms Fatigue und der sensomotorischen Instabilität durch eine individualisierte beanspruchungsgesteuerte Trainingstherapie sowie durch eine intensivierte kognitive Verhaltenstherapie war das übergeordnete Ziel der Interventionsstudie über einen 3‑jährigen Zeitraum (Q1-2021 bis Q4-2023). Methodik Es wurden in den 3 Jahren im Post-COVID-19-Zentrum Lausitz (Senftenberg) 407 geimpfte nukleokapsidpositive Patienten behandelt. Bei 78 (rd. 19 %) von ihnen wurden als Leitsyndrome Fatigue/immunometabolische Depression und sensomotorische Instabilität konstatiert. Die Evaluation der individualisierten beanspruchungsgesteuerten Trainingstherapie erfolgte anhand der konkreten Post-COVID-19-Syndromatik und motorischer Fatigability-Parameter. Die sekundäre psychosomatische Syndromatik wurde mit kognitiven Fatigability-Parametern und mit Instrumenten der kognitiven Verhaltenstherapie bewertet. Die Untersuchung verhaltensbeeinflussender Parameter fand in Q2-2023 bis Q4-2023 mit einem leitfadengestützten qualitativen Interview unter den Therapieteilnehmern statt. Ergebnisse Die Post-COVID-19-Leitsymptomen „Fatigue“, „sensomotorische Instabilität“, „neuropsychiatrische Symptome“, „kardionale/autonome Dysfunktion“ und „Schmerzen“ verbesserten sich signifikant in der Gesamtkohorte sowie bei der geschlechtsspezifischen Analyse. Eine Verschlechterung trat bei „sekundären psychosomatischen Symptomen“ auf. Für alle motorischen Fatigability-Parameter konnte für die Gesamtkohorte mit dem Cohens d-Wert ein therapeutischer Effekt nachgewiesen werden. Positive Wirkungen erzielte eine Intensivierung der kognitiven Verhaltenstherapie durch eine zunehmende Entwicklung der Eigenaktivität der Patienten sowie deren Selbstkontrolle unter Einsatz von Persuasion und Gamification. N2 - Background For the treatment of the symptoms of post-COVID-19 syndrome, no causal therapy is currently widely recommended according to evidence-based criteria. The overarching goal of the intervention study over a 3-year period (Q1-2021–Q4-2023) was to evaluate the changes in the key symptoms of fatigue and sensorimotor instability through individualized stress-controlled training therapy and through intensified cognitive behavioral therapy. Material and methods In the 3‑year period 407 vaccinated nucleocapsid positive patients were treated at the Post-COVID-19 Center Lausitz (Senftenberg). In 78 (around 19%) fatigue/immunometabolic depression and sensorimotor instability were identified as the leading syndromes. The evaluation of the individualized stress-controlled training therapy was based on the specific post-COVID-19 syndrome and motor fatigue parameters. The secondary psychosomatic syndrome was assessed using cognitive fatigue parameters and cognitive behavioral therapy instruments. The investigation of -parameters influencing behavior took place in Q2-2023–Q4-2023 with a guide-supported qualitative interview among the participants. Results The post-COVID-19 key symptoms “fatigue,” “sensorimotor instability,” “neuropsychiatric symptoms,” “cardiac/autonomic dysfunction,” and “pain” improved significantly in the overall cohort and in the gender-specific analysis. A deterioration occurred in “secondary psychosomatic symptoms”. A therapeutic effect was demonstrated for all motor fatigue parameters for the entire cohort using the Cohen’s d value. An intensification of cognitive behavioral therapy achieved positive effects through an increasing development of the patients’ own activity and their self-control using persuasion and gamification. KW - Post-COVID-Syndrom KW - Fatigue KW - Sensomotorische Instabilität KW - Kognitive Verhaltenstherapie KW - Sekundäre psychosomatische Symptome KW - Post-COVID syndrome KW - Fatigue KW - Sensorimotor instability KW - Cognitive behavioral therapy KW - Secondary psychosomatic symptoms Y1 - 2024 U6 - https://doi.org/10.1007/s00115-024-01732-3 SN - 0028-2804 SN - 1433-0407 VL - 95 IS - 12 SP - 1104 EP - 1115 PB - Springer Medizin CY - Heidelberg ER - TY - GEN A1 - Roei, Tulchinsky A1 - Boris, Gilburd A1 - Yehuda, Shovman A1 - Milena, Tocut A1 - Eleanor, Zeruya A1 - Ariel, Binyaminov A1 - Tima, Davidson A1 - Büttner, Thomas A1 - Nasser, Abdullah A1 - Michel, Juliane A1 - Rödiger, Stefan A1 - Schierack, Peter A1 - Howard, Amital A1 - Roggenbuck, Dirk A1 - Yehuda, Shoenfeld A1 - Ora, Shovman T1 - CytoBead ANA 2 assay : a novel method for the detection of antinuclear antibodies T2 - Scientific reports N2 - Detection of anti-nuclear autoantibodies (ANA) is based on a two-step algorithm including indirect immunofluorescence (IIF) on HEp2 cells and subsequent reflex/confirmatory testing for specific autoantibodies. Simultaneous cell- and microbead-based autoantibody detection by IIF may be utilized for the evaluation of systemic autoimmune rheumatic diseases (SARDs). In the present study, we assessed the performance of CytoBead ANA 2 in the detection of ANA and ANA-specific autoantibodies, compared to ANA IIF and BioPlex™ 2200. We also tested the ability of CytoBead ANA DFS-70 to identify dense-fine speckled (DFS) pattern associated with anti-DFS70 antibodies in non-SARDs patients. Hundred-twelve routine sera samples were assessed by manual CytoBead ANA 2 for the presence of ANA and specific autoantibodies. In parallel, these samples were analyzed by HEp2 ANA IIF test and a subsequent multiplexed assay BioPlex™ 2200 ANA. Twenty-nine ANA-positive samples obtained from non-SARDs patients and exhibiting DFS pattern by ANA IIF were further tested by CytoBead ANA DFS-70. A substantial agreement was observed between classical ANA IIF and manual CytoBead ANA 2 for the detection of ANA (k = 0.74). Discordant results were mainly associated with the presence of anti-SSA/Ro antibodies detected by CytoBead ANA 2 in ANA IIF negative patients. A good to almost perfect agreement was found between CytoBead ANA 2 and BioPlex™ 2200 for detection of specific antibodies with kappa values ranging from 0.70 to 0.90. Twenty samples (68.9%) obtained from 29 ANA IIF positive without SARDs patients exhibited DFS pattern in CytoBead ANA DFS-70, which confirmed the presence of anti-DFS70 antibodies. The diagnostic performance of manual CytoBead ANA 2 for ANA screening and detection of ANA specific antibodies is comparable to the diagnostic performance of ANA IIF followed by BioPlex™ 2200. This novel one-step assay enables simultaneous ANA screening and confirmation and represents a promising alternative approach to the time-consuming and costly two-tier ANA analysis. KW - Anti-nuclear antibodies KW - Anti-DFS70 antibodies KW - Indirect immunofluorescence KW - Multiplexed assay KW - CytoBead technology Y1 - 2025 U6 - https://doi.org/10.1038/s41598-025-04583-3 SN - 2045-2322 VL - 15 IS - 1 SP - 1 EP - 11 PB - Nature Publishing Group UK CY - London ER - TY - GEN A1 - Sheppard, Jonathan P. A1 - Bohn Reckziegel, Rafael A1 - Borrass, Lars A1 - Chirwa, Paxie W. A1 - Cuaranhua, Claudio J. A1 - Hassler, Sibylle K A1 - Hoffmeister, Svenja A1 - Kestel, Florian A1 - Maier, Rebekka A1 - Mälicke, Mirko A1 - Morhart, Christopher A1 - Ndlovu, Nicholas P. A1 - Veste, Maik A1 - Funk, Roger A1 - Lang, Friedericke A1 - Seifert, Thomas A1 - du Toit, Ben A1 - Kahle, Hans-Peter T1 - Agroforestry: An Appropriate and Sustainable Response to a Changing Climate in Southern Africa? T2 - Sustainability N2 - Agroforestry is often discussed as a strategy that can be used both for the adaptation to and the mitigation of climate change effects. The climate of southern Africa is predicted to be severely affected by such changes. With agriculture noted as the continent’s largest economic sector, issues such as food security and land degradation are in the forefront. In the light of such concerns we review the current literature to investigate if agroforestry systems (AFS) are a suitable response to the challenges besetting traditional agricultural caused by a changing climate. The benefits bestowed by AFS are multiple, offering ecosystem services, influence over crop production and positive impacts on rural livelihoods through provisioning and income generation. Nevertheless, knowledge gaps remain. We identify outstanding questions requiring further investigation such as the interplay between trees and crops and their combination, with a discussion of potential benefits. Furthermore, we identify deficiencies in the institutional and policy frameworks that underlie the adoption and stimulus of AFS in the southern African region. We uphold the concept that AFS remains an appropriate and sustainable response for an increased resilience against a changing climate in southern Africa for the benefit of livelihoods and multiple environmental values KW - agroforestry KW - Southern Africa Y1 - 2020 UR - https://www.mdpi.com/2071-1050/12/17/6796 U6 - https://doi.org/10.3390/su12176796 VL - 12 IS - 17 ER - TY - GEN A1 - Hofer, Markus A1 - Lehmann, Peter A1 - Schneider, Anna A1 - Maurer, Thomas A1 - Stähli, Manfred A1 - Krafczyk, Manfred T1 - Modelling the emergence of surface erosion rills in an artificial catchment T2 - Structures and processes of the initial ecosystem development, 1st International Conference assoc. with 4th Meeting of Young Researchers in Earth Sciences (MYRES), 20-24 Sept. 2010, Cottbus, Germany Y1 - 2010 SP - S. 53 PB - BTU CY - Cottbus ER - TY - CHAP A1 - Hofer, Markus A1 - Lehmann, Peter A1 - Schneider, Anna A1 - Maurer, Thomas A1 - Stähli, Manfred A1 - Krafczyk, Manfred T1 - Modelling the emergence of surface erosion rills in an artificial catchment T2 - EGU General Assembly 2010, held in Vienna, Austria, 02 – 07 May 2010 Y1 - 2010 N1 - EGU2010-2498 PB - European Geophysical Society CY - Katlenburg-Lindau ER - TY - GEN A1 - Dietrich, Lucas A1 - Förster, Benjamin A1 - Langendörfer, Peter A1 - Hinze, Thomas T1 - A visual discrete event-based simulator for protection of plants against herbivores employed as computational optimization game N2 - Plants come with sophisticated strategies to survive within a highly competing environment. In addition, they need to resist frequent attacks from a variety of herbivores acting alone, in small groups, or in swarms. Since the amount of energy a plant might invest in defense and reproduction is limited, a complex optimization problem emerges. In a shared habitat, plants fight herbivores by shape and camouflage, by the release of specific toxins, or by attracting predators of herbivores. Furthermore, plants alert their surrounding field by signaling substances in the event of an assault. Transported by air or through a network of roots, signaling substances reach neighbors to trigger their defense. The offsprings of a plant commonly grow within a certain distance to benefit from symbiotic protection. We introduce a grid-based visual simulation software for detailed configuration and subsequent processing of the behavior of the resulting system in time and space. In terms of solution to a computational optimization problem inspired by nature, settings with low energy need and long life able to cope with different patterns of attack can be figured out and analyzed. Applications include novel techniques for efficient construction and secure operation of sensor networks. KW - Plant defense KW - Event-based simulation KW - Topological optimization Y1 - 2025 U6 - https://doi.org/10.48550/arXiv.2509.15787 SP - 1 EP - 25 PB - arXiv ER - TY - GEN A1 - Sovová, Lucie A1 - Cima, Ottavia A1 - Jehlička, Petr A1 - Pungas, Lilian A1 - Sattler, Markus A1 - Smith, Thomas S.J. A1 - Decker, Anja A1 - Johanisova, Nadia A1 - Kovanen, Sunna A1 - North, Peter T1 - On Babushkas and postcapitalism : theorising diverse economies from the Global East T2 - Antipode : a radical journal of geography N2 - As transformative visions for more just and sustainable societies multiply around the globe, the Diverse and Community Economies approach presents one of the most influential strategies to advance postcapitalist visions. In this paper, we contribute to this project based on our research and activism in the Global East, intended here as Central and Eastern Europe and the former Soviet Union. We argue that engaging with the Global East is not only a matter of epistemic inclusivity but also a (too‐often‐neglected) opportunity to learn from a region with a history of dramatic economic transformation and diversity. We highlight examples of community economies already contributing to more‐than‐human wellbeing, and we present emerging theoretical insights concerning temporality, the multi‐sitedness of the enterprise, and diverse economic subjectivities. With that, we articulate our ongoing research agenda and advance conversations with postcapitalist scholarship and politics. KW - Global East KW - Diverse economies KW - Epistemic inclusivity KW - Postcapitalist politics KW - Community economies KW - Postsocialism Y1 - 2025 U6 - https://doi.org/10.1111/anti.70034 SN - 0066-4812 SN - 1467-8330 VL - 57 IS - 6 SP - 2484 EP - 2507 PB - Wiley CY - Hoboken, NJ ER -