TY - GEN A1 - Schierack, Peter A1 - Heiden, Stefan E. A1 - Khan, Muhammad Moman A1 - Nikolaus, Lena A1 - Kolenda, Rafał A1 - Stubbe, Michael A1 - Lkhagvasuren, Davaa A1 - Rödiger, Stefan A1 - Guenther, Sebastian A1 - Schaufler, Katharina T1 - Genomic and Phenotypic Analysis of an ESBL-Producing E. coli ST1159 Clonal Lineage From Wild Birds in Mongolia T2 - Frontiers in Microbiology Y1 - 2020 U6 - https://doi.org/10.3389/fmicb.2020.01699 SN - 1664-302X VL - 11 ER - TY - GEN A1 - Reimann, Ronny A1 - Rödiger, Stefan A1 - Stein, Erhard A1 - Kilian, Andrè A1 - Dittrich, Corinne A1 - Petrick, Ingolf T1 - Die Beschreibung der Fluiddynamik und der Lichtintensität im neuen MULT Reaktor KW - Photobioreaktor KW - Fluiddynamik KW - Lichtintensität Y1 - 2013 N1 - Algen und die globalen Megatrends, Tagungsband, 6. Bundesalgenstammtisch, 13. und 14. Mai 2013 Bürgerhaus Wilhelmsburg, Hamburg-Wilhelmsburg SP - S. 30 PB - DECHEMA CY - Frankfurt, M. ER - TY - GEN A1 - George, Sandra A1 - Rödiger, Stefan A1 - Schröder, Christian A1 - Knaut, Michael A1 - Küpper, Jan-Heiner T1 - Development of multiplex PCR systems for expression profiling of human cardiomyocytes induced to profilerate by lentivirus transduction of upcyte genes T2 - Journal of Cellular Biotechnology Y1 - 2016 U6 - https://doi.org/10.3233/JCB-15025 SN - 2352-3697 SN - 2352-3689 VL - 2 IS - 1 SP - 35 EP - 55 ER - TY - GEN A1 - Gruner, Melanie A1 - Moncsek, Anja A1 - Rödiger, Stefan A1 - Kühnhardt, Dagmar A1 - Feist, Eugen A1 - Stohwasser, Ralf T1 - Increased proteasome activator 28 gamma (PA28g) levels are unspecific but correlate with disease activity in rheumatoid arthritis T2 - BMC musculoskeletal disorders Y1 - 2014 U6 - https://doi.org/10.1186/1471-2474-15-414 SN - 1471-2474 VL - 15 SP - 414 EP - 424 ER - TY - GEN A1 - Choi, Youngeun A1 - Schmidt, Carsten A1 - Tinnefeld, Philip A1 - Bald, Ilko A1 - Rödiger, Stefan T1 - A new reporter design based on DNA origami nanostructures for quantification of short oligonucleotides using microbeads T2 - Scientific Reports Y1 - 2019 U6 - https://doi.org/10.1038/s41598-019-41136-x. SN - 2045-2322 IS - 9 ER - TY - GEN A1 - Whale, Alexandra S. A1 - Spiegelaere, Ward De A1 - Trypsteen, W. A1 - Nour, Afif Abdel A1 - Bae, Young-Kyung A1 - Benes, Vladimir A1 - Cleveland, Megan A1 - Devonshire, Alison S. A1 - Dong, Lianhua A1 - Drandi, Daniela A1 - Foy, Carole A. A1 - Garson, Jeremy A. A1 - He, Hua-Jun A1 - Hellemans, Jan A1 - Kubista, Mikael A1 - Lievens, Antoon A1 - Makrigiogos, Mike G. A1 - Müller, Reinhold D. A1 - Nolan, Tania A1 - O'Sullivan, Denise M. A1 - Pfaffl, Michael W. A1 - Rödiger, Stefan A1 - Romsos, Erica L. A1 - Shipley, Gregory L. A1 - Taly, Valerie A1 - Untergasser, Andreas A1 - Wittwer, Carl T. A1 - Bustin, Stephen A. A1 - Vandesompele, Jo A1 - Huggett, Jim F. T1 - The Digital MIQE Guidelines Update: Minimum Information for Publication of Quantitative Digital PCR Experiments for 2020 T2 - Clinical Chemistry Y1 - 2020 U6 - https://doi.org/10.1093/clinchem/hvaa125 SN - 0009-9147 SN - 1530-8561 VL - 66 IS - 8 SP - 1012 EP - 1029 ER - TY - GEN A1 - Dinter, Franziska A1 - Jurischka, Christoph A1 - Weiss, Romano A1 - Rödiger, Stefan T1 - Multiparametrische Antikörperdetektion für die Diagnostik T2 - BIOspektrum Y1 - 2020 U6 - https://doi.org/10.1077/s12268-020-1375-5 SN - 1868-6249 SN - 0947-0867 VL - 26 IS - 3 SP - 265 EP - 267 ER - TY - GEN A1 - Chilimoniuk, Jarosław A1 - Gosiewska, Alicja A1 - Słowik, Jadwiga A1 - Weiss, Romano A1 - Deckert, P. Markus A1 - Rödiger, Stefan A1 - Burdukiewicz, Michał T1 - coutfitteR: efficient selection of count distributions to assess DNA damage T2 - Annals of Translational Medicine Y1 - 2021 U6 - https://doi.org/10.21037/atm-20-6363 SN - 2305-5847 VL - 9 IS - 7 ER - TY - GEN A1 - Fischer, Thomas A1 - Marchetti-Deschmann, Martina A1 - Assis, Ana Cristina A1 - Elad, Michal Levin A1 - Algarra, Manuel A1 - Barac, Marko A1 - Bogdanovic Radovic, Iva A1 - Cicconi, Flavio A1 - Claes, Britt A1 - Frascione, Nunzianda A1 - George, Sony A1 - Guedes, Alexandra A1 - Heaton, Cameron A1 - Heeren, Ron A1 - Lasic, Violeta A1 - Lerma, José Luis A1 - del Valle Martinez de Yuso Garcia, Maria A1 - Nosko, Martin A1 - O'Hara, John A1 - Oshina, Ilze A1 - Palucci, Antonio A1 - Pawlaczyk, Aleksandra A1 - Pospíšková, Kristýna A1 - de Puit, Marcel A1 - Radodic, Ksenija A1 - Rēpele, Māra A1 - Ristova, Mimoza A1 - Romolo, Francesco Saverio A1 - Šafařík, Ivo A1 - Siketic, Zdravko A1 - Spigulis, Janis A1 - Szynkowska-Jozwik, Malgorzata Iwona A1 - Tsiatsiuyeu, Andrei A1 - Vella, Joanna A1 - Dawson, Lorna A1 - Rödiger, Stefan A1 - Francese, Simona T1 - Profiling and imaging of forensic evidence – A pan-European forensic round robin study part 1: Document forgery T2 - Science & Justice Y1 - 2022 U6 - https://doi.org/10.1016/j.scijus.2022.06.001 SN - 1876-4452 SN - 1355-0306 VL - 62 IS - 4 SP - 433 EP - 447 ER - TY - CHAP A1 - Rödiger, Stefan A1 - Burdukiewicz, Michał T1 - Reproducible Analysis of DNA Amplification Experiments with an Open Source Software Environment T2 - Abstractbook, 67th Annual Meeting of the German Society of Hygiene and Microbiology (DGHM), 27.-30.09.2015, Münster Y1 - 2015 UR - https://www.dghm.org/wp-content/uploads/2018/07/783_dghm2015_abstractbook_update.pdf ER - TY - CHAP A1 - Rödiger, Stefan T1 - Applications of a Multipurpose Platf orm for the Detection and Analysis of Biomolecules T2 - BioSensor, 9. Deutsches BioSensor Symposium, 11.-13. März 2015 Y1 - 2015 PB - München ER - TY - GEN A1 - Spiess, Andrej-Nikolai A1 - Rödiger, Stefan A1 - Burdukiewicz, Michał A1 - Volksdorf, Thomas A1 - Tellinghuisen, Joel T1 - System-specific periodicity in quantitative real-time polymerase chain reaction data questions threshold-based quantitation T2 - Scientific Reports Y1 - 2016 U6 - https://doi.org/10.1038/srep38951 SN - 2045-2322 VL - 6 ER - TY - GEN A1 - Burdukiewicz, Michał A1 - Sobczyk, Piotr A1 - Rödiger, Stefan A1 - Duda-Madej, Anna A1 - Mackiewicz, Pawel A1 - Kotulska, Malgorzata T1 - Amyloidogenic motifs revealed by n-gram analysis T2 - Scientific Reports Y1 - 2017 U6 - https://doi.org/10.1038/s41598-017-13210-9 SN - 2045-2322 VL - 7 ER - TY - GEN A1 - Rödiger, Stefan A1 - Liefold, Marius A1 - Ruhe, Madeleine A1 - Reinwald, Mark A1 - Beck, Eberhard A1 - Deckert, P. Markus T1 - Quantification of DNA double-strand breaks in peripheral blood mononuclear cells from healthy donors exposed to bendamustine by an automated H2AX assay- an exploratory study T2 - Journal of Laboratory and Precision Medicine Y1 - 2018 U6 - https://doi.org/10.21037/jlpm.2018.04.10 SN - 2519-9005 VL - 3 IS - 47 ER - TY - GEN A1 - Schmidt, Carsten A1 - Rödiger, Stefan A1 - Gruner, Melanie A1 - Moncsek, Anja A1 - Stohwasser, Ralf A1 - Hanack, Katja A1 - Schierack, Peter A1 - Schröder, Christian T1 - Multiplex localization of sequential peptide epitopes by use of a planar microbead chip T2 - Analytica Chimica Acta Y1 - 2016 U6 - https://doi.org/10.1016/j.aca.2015.12.030 SN - 0003-2670 VL - 908 SP - 150 EP - 160 ER - TY - GEN A1 - Ruhe, Madeleine A1 - Rabe, Dominik A1 - Jurischka, Christoph A1 - Schröder, Julia A1 - Schierack, Peter A1 - Deckert, P. Markus A1 - Rödiger, Stefan T1 - Molecular biomarkers of DNA damage in diffuse large-cell lymphoma-a review T2 - Journal of Laboratory and Precision Medicine Y1 - 2019 U6 - https://doi.org/10.21037/jlpm.2019.01.01 SN - 2519-9005 VL - 4 ER - TY - GEN A1 - Schmidt, Jonas A1 - Berghaus, Sandro A1 - Blessing, Frithjof A1 - Wenzel, Folker A1 - Herbeck, Holger A1 - Blessing, Josef A1 - Schierack, Peter A1 - Rödiger, Stefan A1 - Roggenbuck, Dirk T1 - A semi-automated, isolation-free, high-throughput SARS-CoV-2 reverse transcriptase (RT) loop-mediated isothermal amplification (LAMP) test T2 - Scientific reports Y1 - 2021 U6 - https://doi.org/10.1038/s41598-021-00827-0 SN - 2045-2322 VL - 11 IS - 1 ER - TY - GEN A1 - Frömmel, Ulrike A1 - Lehmann, Werner A1 - Rödiger, Stefan A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Weinreich, Jörg A1 - Groß, Julia A1 - Roggenbuck, Dirk A1 - Zinke, Olaf A1 - Ansorge, Hermann A1 - Vogel, Steffen A1 - Klemm, Per A1 - Wex, Thomas A1 - Schröder, Christian A1 - Wieler, Lothar H. A1 - Schierack, Peter T1 - Adhesion of human and animal Escherichia coli strains in association with their virulence-associated genes and phylogenetic origins T2 - Applied and environmental microbiology N2 - Intestinal colonization is influenced by the ability of the bacterium to inhabit a niche, which is based on the expression of colonization factors. Escherichia coli carries a broad range of virulence-associated genes (VAGs) which contribute to intestinal (inVAGs) and extraintestinal (exVAGs) infection. Moreover, initial evidence indicates that inVAGs and exVAGs support intestinal colonization. We developed new screening tools to genotypically and phenotypically characterize E. coli isolates originating in humans, domestic pigs, and 17 wild mammal and avian species. We analyzed 317 isolates for the occurrence of 44 VAGs using a novel multiplex PCR microbead assay (MPMA) and for adhesion to four epithelial cell lines using a new adhesion assay. We correlated data for the definition of new adhesion genes. inVAGs were identified only sporadically, particularly in roe deer (Capreolus capreolus) and the European hedgehog ( Erinaceus europaeus). The prevalence of exVAGs depended on isolation from a specific host. Human uropathogenic E. coli isolates carried exVAGs with the highest prevalence, followed by badger (Meles meles) and roe deer isolates. Adhesion was found to be very diverse. Adhesion was specific to cells, host, and tissue, though it was also unspecific. Occurrence of the following VAGs was associated with a higher rate of adhesion to one or more cell lines: afa-dra, daaD, tsh, vat, ibeA, fyuA, mat, sfa-foc, malX, pic, irp2, and papC. In summary, we established new screening methods which enabled us to characterize large numbers of E. coli isolates. We defined reservoirs for potential pathogenic E. coli. We also identified a very broad range of colonization strategies and defined potential new adhesion genes. Y1 - 2013 U6 - https://doi.org/10.1128/AEM.01384-13 SN - 1098-5336 SN - 0099-2240 VL - 79 IS - 19 SP - 5814 EP - 5829 ER - TY - GEN A1 - Schierack, Peter A1 - Rödiger, Stefan A1 - Kuhl, Christoph A1 - Hiemann, Rico A1 - Roggenbuck, Dirk A1 - Li, Ganwu A1 - Weinreich, Jörg A1 - Berger, Enrico A1 - Nolan, Lisa K. A1 - Nicholson, Bryon A1 - Römer, Antje A1 - Frömmel, Ulrike A1 - Wieler, Lothar H. A1 - Schröder, Christian T1 - Porcine E. coli: Virulence-Associated Genes, Resistance Genes and Adhesion and Probiotic Activity Tested by a New Screening Method T2 - PLoS One N2 - We established an automated screening method to characterize adhesion of Escherichia coli to intestinal porcine epithelial cells (IPEC-J2) and their probiotic activity against infection by enteropathogenic E. coli (EPEC). 104 intestinal E. coli isolates from domestic pigs were tested by PCR for the occurrence of virulence-associated genes, genes coding for resistances to antimicrobial agents and metals, and for phylogenetic origin by PCR. Adhesion rates and probiotic activity were examined for correlation with the presence of these genes. Finally, data were compared with those from 93 E. coli isolates from wild boars. Isolates from domestic pigs carried a broad variety of all tested genes and showed great diversity in gene patterns. Adhesions varied with a maximum of 18.3 or 24.2 mean bacteria adherence per epithelial cell after 2 or 6 hours respectively. Most isolates from domestic pigs and wild boars showed low adherence, with no correlation between adhesion/probiotic activity and E. coli genes or gene clusters. The gene sfa/foc, encoding for a subunit of F1C fimbriae did show a positive correlative association with adherence and probiotic activity; however E. coli isolates from wild boars with the sfa/foc gene showed less adhesion and probiotic activity than E. coli with the sfa/foc gene isolated from domestic pigs after 6 hour incubation. In conclusion, screening porcine E. coli for virulence associated genes genes, adhesion to intestinal epithelial cells, and probiotic activity revealed a single important adhesion factor, several probiotic candidates, and showed important differences between E. coli of domestic pigs and wild boars. Y1 - 2013 U6 - https://doi.org/10.1371/journal.pone.0059242 VL - 8 IS - 4 ER - TY - GEN A1 - Rödiger, Stefan A1 - Lehmann, Werner A1 - Frömmel, Ulrike A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Burdukiewicz, Michał A1 - Schröder, Christian A1 - Dangla, Rémi A1 - Droniou, Magali A1 - Schierack, Peter T1 - The Modi Operandi of the VideoScan Platform for the Detection and Analysis of Nucleic Acids. Life Science Day 2013 & 17. Leibniz Conference of Advanced Science, Freie Universität Berlin, 24.10.2013 Y1 - 2013 UR - https://leibniz-institut.de/Konferenzen/lsd2013/roediger_the_modi_operandi_of_the_videoscan_platform.pdf ER -