TY - GEN A1 - Lehnen, Nadine A1 - Ramaioli, Cecilia A1 - Henningsen, Peter A1 - Glasauer, Stefan T1 - An experimental litmus test of the emerging hypothesis that persistent physical symptoms can be explained as perceptual dysregulation T2 - Journal of Psychosomatic Research Y1 - 2018 U6 - https://doi.org/10.1016/j.jpsychores.2018.08.007 SN - 1879-1360 SN - 0022-3999 VL - 114 SP - 15 EP - 17 ER - TY - GEN A1 - Xiang, Min A1 - Seemungal, Barry M. A1 - Glasauer, Stefan T1 - Quantitative postural models as biomarkers of balance in Parkinson’s disease T2 - Brain Y1 - 2018 U6 - https://doi.org/10.1093/brain/awy250 SN - 0006-8950 SN - 1460-2156 VL - 141 IS - 10 SP - 2824 EP - 2827 ER - TY - GEN A1 - Glasauer, Stefan A1 - Dieterich, Marianne A1 - Brandt, Thomas T1 - Neuronal network-based mathematical modeling of perceived verticality in acute unilateral vestibular lesions: from nerve to thalamus and cortex T2 - Journal of Neurology Y1 - 2018 U6 - https://doi.org/10.1007/s00415-018-8909-5 SN - 1432-1459 SN - 0340-5354 VL - 265 IS - Supplement 1 SP - 112 ER - TY - GEN A1 - Chen, Siyi A1 - Glasauer, Stefan A1 - Müller, Hermann J. A1 - Conci, Markus T1 - Surface filling-in and contour interpolation contribute independently to Kanizsa figure formation T2 - Journal of Experimental Psychology Y1 - 2018 U6 - https://doi.org/10.1037/xhp0000540 SN - 1939-1277 SN - 0096-1523 VL - 44 IS - 9 SP - 1399 EP - 1413 ER - TY - GEN A1 - Salmasi, Mehrdad A1 - Loebel, Alex A1 - Glasauer, Stefan A1 - Stemmler, Martin T1 - Short-term synaptic depression can increase the rate of information transfer at a release site T2 - PLoS Computational Biology N2 - The release of neurotransmitters from synapses obeys complex and stochastic dynamics. Depending on the recent history of synaptic activation, many synapses depress the probability of releasing more neurotransmitter, which is known as synaptic depression. Our understanding of how synaptic depression affects the information efficacy, however, is limited. Here we propose a mathematically tractable model of both synchronous spike-evoked release and asynchronous release that permits us to quantify the information conveyed by a synapse. The model transits between discrete states of a communication channel, with the present state depending on many past time steps, emulating the gradual depression and exponential recovery of the synapse. Asynchronous and spontaneous releases play a critical role in shaping the information efficacy of the synapse. We prove that depression can enhance both the information rate and the information rate per unit energy expended, provided that synchronous spike-evoked release depresses less (or recovers faster) than asynchronous release. Furthermore, we explore the theoretical implications of short-term synaptic depression adapting on longer time scales, as part of the phenomenon of metaplasticity. In particular, we show that a synapse can adjust its energy expenditure by changing the dynamics of short-term synaptic depression without affecting the net information conveyed by each successful release. Moreover, the optimal input spike rate is independent of the amplitude or time constant of synaptic depression. We analyze the information efficacy of three types of synapses for which the short-term dynamics of both synchronous and asynchronous release have been experimentally measured. In hippocampal autaptic synapses, the persistence of asynchronous release during depression cannot compensate for the reduction of synchronous release, so that the rate of information transmission declines with synaptic depression. In the calyx of Held, the information rate per release remains constant despite large variations in the measured asynchronous release rate. Lastly, we show that dopamine, by controlling asynchronous release in corticostriatal synapses, increases the synaptic information efficacy in nucleus accumbens. Y1 - 2019 UR - https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1006666 U6 - https://doi.org/10.1371/journal.pcbi.1006666 SN - 1553-7358 SN - 1553-734X VL - 15 ER - TY - GEN A1 - MacNeilage, Paul R. A1 - Glasauer, Stefan T1 - Perceiving gravity: the role of the cerebellum T2 - Current Biology Y1 - 2018 U6 - https://doi.org/10.1016/j.cub.2018.09.053 SN - 1879-0445 SN - 0960-9822 VL - 28 IS - 22 SP - 1296 EP - 1298 ER - TY - JOUR A1 - Glasauer, Stefan T1 - Ferrè, Elisa Raffaella (Hrsg.): Vestibular Cognition. Leiden [u.a.] Boston : Brill, 2017 JF - Perception Y1 - 2018 SN - 1468-4233 VL - 47 IS - 7 SP - 799 EP - 801 ER - TY - GEN A1 - Kupferberg, Aleksandra A1 - Iacoboni, Marco A1 - Flanagin, Virginia A1 - Huber, Markus A1 - Kasparbauer, Anna A1 - Baumgartner, Thomas A1 - Hasler, Gregor A1 - Schmidt, Florian A1 - Borst, Christoph A1 - Glasauer, Stefan T1 - Fronto-parietal coding of goal-directed actions performed by artificial agents T2 - Human Brain Mapping Y1 - 2018 U6 - https://doi.org/10.1002/hbm.23905 SN - 1097-0193 SN - 1065-9471 VL - 39 IS - 3 SP - 1145 EP - 1162 ER - TY - GEN A1 - Choi, Jeong-Yoon A1 - Glasauer, Stefan A1 - Zee, David S. A1 - Kim, Ji-Soo T1 - Characteristics and Mechanism of Apogeotropic Central Positional Nystagmus T2 - Brain Y1 - 2018 U6 - https://doi.org/10.1093/brain/awx381 SN - 1460-2156 SN - 0006-8950 VL - 141 IS - 3 SP - 762 EP - 775 ER - TY - GEN A1 - Dieterich, Marianne A1 - Glasauer, Stefan A1 - Brandt, Thomas T1 - Why acute unilateral vestibular midbrain lesions rarely manifest with rotational vertigo: a clinical and modelling approach to head direction cell function. T2 - Journal of Neurology Y1 - 2018 U6 - https://doi.org/10.1007/s00415-018-8828-5 SN - 0340-5354 SN - 1432-1459 VL - 265 IS - 5 SP - 1184 EP - 1198 ER -