TY - GEN A1 - Schnitzlein, Klaus A1 - Otto, Olaf T1 - Thermobalance for Kinetic Investigations of Heterogeneous Catalysts T2 - Chemical engineering & technology Y1 - 2001 VL - 24 IS - 9 SP - 894 EP - 897 ER - TY - GEN A1 - Eisfeld, Bernhard A1 - Schnitzlein, Klaus T1 - The influence of confining walls on the pressure drop in packed beds T2 - Chemical Engineering Science Y1 - 2001 SN - 0009-2509 VL - 56 IS - 14 SP - 4321 EP - 4329 ER - TY - CHAP A1 - Schnitzlein, Klaus A1 - Thies, Jens T1 - Reassessment of the concentration controlled recycle reactor for kinetic investigations of heterogeneous catalytic reactions T2 - ECCE - 3rd European Congress of Chemical Engineering, Nuremberg 26 - 28 June 2001 Y1 - 2001 PB - DECHEMA CY - Frankfurt am Main ER - TY - GEN A1 - Schnitzlein, Klaus T1 - The Impact of Fluid Dynamics on the Regeneration of Automotive Fiber Coil Filters III. Nonuniform Fluid Distribution T2 - Chemical engineering & technology Y1 - 2001 SN - 0930-7516 SN - 1521-4125 VL - 24 IS - 12 SP - 1281 EP - 1287 ER - TY - GEN A1 - Schnitzlein, Klaus T1 - A Note on Factorial Designs for Kinetic Investigations of Heterogeneous Catalytic Reactions in Differential Recycle Reactors T2 - Chemical engineering & technology Y1 - 2002 SN - 0930-7516 SN - 1521-4125 VL - 25 IS - 8 SP - 819 EP - 822 ER - TY - GEN A1 - Saulich, Katja A1 - Schnitzlein, Klaus T1 - On-line Monitoring der lipase-katalysierten Hydrolyse von Rapsöl T2 - Forum der Forschung Y1 - 2002 SN - 0947-6989 VL - 15 IS - 8 SP - 57 EP - 60 ER - TY - CHAP A1 - Thies, Jens A1 - Schnitzlein, Klaus T1 - Kinetische Untersuchungen von Reaktionssystemen mit inhibierenden Komponenten: Der Einfluß des Wassers bei der Methanoloxidation am Fe/Mo-Kontakt T2 - 3. Merseburger Fachtagung Automatisierung, Meßmethoden und Experimente in der chemischen Reaktionstechnik Y1 - 1997 PB - Verein Deutscher Ingenieure CY - Düsseldorf ER - TY - GEN A1 - Schnitzlein, Klaus A1 - Ratte, Thomas T1 - The Impact of Fluid Dynamics on the Regeneration of Automative Fiber Coil Filters II. Direct and Indirect Interactions T2 - Chemical engineering & technology Y1 - 1998 SN - 0930-7516 SN - 1521-4125 VL - 21 IS - 2 SP - 179 EP - 186 ER - TY - GEN A1 - Schnitzlein, Klaus A1 - Otto, Olaf T1 - Thermowaage mit intelligenter Gasdosiereinheit zur reaktionstechnischen Untersuchung heterogener Katalysatoren T2 - Chemie Ingenieur Technik Y1 - 1999 SN - 0009-286X SN - 1522-2640 VL - 71 IS - 9 ER - TY - CHAP A1 - Limberg, Carsten A1 - Schnitzlein, Klaus T1 - Computergenerierte Modellschüttungen - eine Alternative zur experimentellen Ermittlung der lokalen Struktur von Partikelschüttungen T2 - Corrosion monitoring - damit ein Schaden erst gar nicht entsteht, Dechema Jahrestagung Wiesbaden 11. und 12. November 2003 Y1 - 2003 SN - 3-935406-08-8 SP - 305 EP - 307 PB - GfKORR CY - Frankfurt am Main ER - TY - GEN A1 - Schnitzlein, Klaus T1 - Modelling radial dispersion in terms of the local structure of packed beds T2 - Chemical Engineering Science Y1 - 2001 SN - 0009-2509 VL - 56 IS - 2 SP - 579 EP - 585 ER - TY - GEN A1 - Machefer, Stephan A1 - Schnitzlein, Klaus T1 - Prozessmodellierung mit künstlichen neuronalen Netzen: Bedeutung des Daten-Preprocessing KW - Prozessmodellierung KW - neuronale Netze KW - Daten-Preprocessing Y1 - 2004 ER - TY - GEN A1 - Eisfeld, Bernhard A1 - Schnitzlein, Klaus T1 - A new pseudo-continous model for the fluid flow in packed beds KW - fluid flow KW - packed bed Y1 - 2005 ER - TY - GEN A1 - Papadokonstantakis, Stavros A1 - Machefer, Stephan A1 - Schnitzlein, Klaus T1 - Variable selection and data preprocessing in NN modelling of complex chemical processes KW - Neural networks KW - Process modelling KW - Data Preprocessing KW - Variable selection KW - Variable information Y1 - 2005 ER - TY - GEN A1 - Saulich, Katja A1 - Schnitzlein, Klaus T1 - On-line monitoring der lipasekatalysierten Hydrolyse von Rapsöl KW - Lipase KW - Katalyse KW - Hydrolyse KW - Rapsöl Y1 - 2004 ER - TY - GEN A1 - Machefer, Stephan A1 - Schnitzlein, Klaus T1 - Relevanz eines informationstheoretrischen Preprocessings bei der Prozeßmodellierung mit Neuronalen Netzen Y1 - 2006 ER - TY - GEN A1 - Saulich, Katja A1 - Schnitzlein, Klaus T1 - Biokatalytische Hydrolyse von Rapsöl zur Herstellung von Fettsäuren - Charakterisierung der mittleren umsatzabhängigen Größe der Phasengrenzfläche Y1 - 2006 ER - TY - GEN A1 - Krautwald, Judith A1 - Schnitzlein, Klaus T1 - Entwicklung eines Thermogravimetrie-Reaktors zur reaktionskinetischen Untersuchung heterogen katalytischer Reaktionen Y1 - 2007 ER - TY - GEN A1 - Machefer, Stephan A1 - Schnitzlein, Klaus T1 - Simple Determination of Segment Numbers for Complex Polymer-Solvent Systems Y1 - 2007 ER - TY - GEN A1 - Machefer, Stephan A1 - Schnitzlein, Klaus T1 - Ideal Mixing Rules for the Viscosity of Complex Polymer-Solvent Mixtures: Assessment of Segment-Fraction Approximations Y1 - 2006 ER - TY - GEN A1 - Machefer, Stephan A1 - Huddar, Mahesh M. A1 - Schnitzlein, Klaus T1 - Effect of polymer admixtures on the growth habit of ionic crystals : Study on crystal growth kinetics of potassium dihydrogen phosphate in water/polyol mixtures T2 - Journal of Crystal Growth Y1 - 2008 SN - 0022-0248 VL - 310 IS - 24 SP - 5347 EP - 5356 ER - TY - GEN A1 - Machefer, Stephan A1 - Schnitzlein, Klaus T1 - Experimental Study on the Effect of Polyol Admixtures on the Interfacial Tension of Potassium Dihydrogen Phosphate in Aequous Solutions: Induction Time Experiments Versus Drop Shape Analysis Y1 - 2009 ER - TY - CHAP A1 - Schwidder, Sabine A1 - Schnitzlein, Klaus T1 - Vorhersage des lokalen statischen Holdups in Rieselbettreaktoren T2 - Jahrestreffen Reaktionstechnik 2009, 8. - 10. Juni 2009, Festung Marienberg, Würzburg Y1 - 2009 PB - DECHEMA CY - Frankfurt am Main ER - TY - CHAP A1 - Schwidder, Sabine A1 - Schnitzlein, Klaus T1 - Prediction of liquid flow distribution in trickle bed reactors in terms of liquid/solid properties T2 - PRES 2010, CHISA 2010, 7th European Congress of Chemical Engineering, ECCE-7, 28 Aug. - 1 Sept. 2010, Prague, Czech Republic Y1 - 2010 SN - 978-88-956080-5-1 PB - AIDIC Servizi S.r.l CY - Milano ER - TY - CHAP A1 - Krautwald, Judith A1 - Schnitzlein, Klaus T1 - Thermogravimetrie-Reaktor fuer reaktionstechnische Untersuchungen in konventionellen Thermowaagen bei definierten Stroemungsverhaeltnissen T2 - Tagungshandbuch, Jahrestreffen Reaktionstechnik 2008, 18. - 20. Mai 2008, Festung Marienberg, Würzburg Y1 - 2008 PB - DECHEMA CY - Frankfurt am Main ER - TY - GEN A1 - Schwidder, Sabine A1 - Schnitzlein, Klaus T1 - Predicting the static liquid holdup for cylindrical packings of spheres in terms of the local structure of the packed bed Y1 - 2010 ER - TY - GEN A1 - Machefer, Stephan A1 - Schnitzlein, Klaus T1 - Inline Concentration Monitoring of Binary Liquid Mixtures in the Presence of a Dispersed Gas Phase with a Modified Speed of Sound Immersion Probe Y1 - 2007 ER - TY - GEN A1 - Schwidder, Sabine A1 - Machefer, Stephan A1 - Schnitzlein, Klaus T1 - Konzentrationsmonitoring bei Gas/Fluessig-Reaktionen mittels einer modifizierten Schallgeschwindigkeits-Sonde Y1 - 2008 ER - TY - GEN A1 - Buchholz, Ina von A1 - Schnitzlein, Klaus T1 - Bestimmung von Dampf/Fluessig-Gleichgewichtsdaten mittels Differenzialkalorimetrie - Experiment und theoretische Validierung Y1 - 2008 ER - TY - GEN A1 - Machefer, Stephan A1 - Grasemann, Martin A1 - Schnitzlein, Klaus T1 - Perspective for Extended Group-Contribution Methods for the Prediction of Activity Coefficients Accounting for Sterical Effects : Linking UNIFAC and the Group Vector Space Method T2 - Industrial & Engineering Chemistry Research Y1 - 2008 U6 - https://doi.org/10.1021/ie800980m SN - 0888-5885 VL - 47 IS - 24 SP - 10080 EP - 10085 ER - TY - GEN A1 - Machefer, Stephan A1 - Schnitzlein, Klaus T1 - Modeling the Mean Ionic Activity Coefficient of Inorganic Salts in Complex Polymer/Water Mixtures : Application of the Segment e-NRTL Model Y1 - 2008 ER - TY - GEN A1 - Machefer, Stephan A1 - Schnitzlein, Klaus T1 - Surface Specific Mixing Rule for Ionic Diffusion Coefficients at Infinite Dilution in Polymer/Water Mixtures Y1 - 2008 ER - TY - CHAP A1 - Schwidder, Sabine A1 - Heinzelmann, Norbert A1 - Schnitzlein, Klaus T1 - Interactive simulation program for the analysis and design of trickle bed reactors T2 - CAMURE 8 & ISMR 7, Naantali, Finland, May 22-25, 2011 Y1 - 2011 SN - 978-952-12-2586-4 PB - Åbo Akademi University CY - Turku ER - TY - CHAP A1 - Schwidder, Sabine A1 - Schnitzlein, Klaus T1 - Predicting the static liquid holdup in trickle bed reactors in terms of the local structure of the packed bed T2 - ISCRE 21, 21st International Symposium on Chemical Reaction Engineering, Sunday, June 13 - Wednesday, June 16, 2010, Philadelphia, PA, USA Y1 - 2010 UR - http://www.iscre.org/iscre21/abstracts/96.pdf ER - TY - CHAP A1 - Muth, Marco A1 - Schmid, Reiner P. A1 - Schnitzlein, Klaus T1 - Specific modifications to enhance sensitivity in null-ellipsometry T2 - Book of abstracts, 8th Workshop Ellipsometry, March 10 - 12, 2014, Dresden, Germany Y1 - 2014 UR - http://www.ipfdd.de/fileadmin/user_upload/ax/OEA/8th_Workshop_Ellipsometry/Book%20of%20abstracts.pdf SP - S. 84 ER - TY - CHAP A1 - Muth, Marco A1 - Schmid, Reiner P. A1 - Schnitzlein, Klaus T1 - Einfache Methode zur Steigerung der Empfindlichkeit in Null-Ellipsometrie T2 - DPG Frühjahrstagung 2013 in Regensburg Y1 - 2013 UR - http://www.dpg-verhandlungen.de/year/2013/conference/regensburg/part/ds/session/30/contribution/10 PB - DPG CY - Bad Honnef ER - TY - CHAP A1 - Hundt, Martin A1 - Schnitzlein, Klaus T1 - The impact of pulp properties on the performance of enzymatic hydrolysis T2 - Italic 6, Science & Technology of biomasses: Advances and Challenges - Proceedings Y1 - 2011 SN - 978-88-95688-65-7 SP - 331 EP - 334 ER - TY - GEN A1 - Schnitzlein, Klaus T1 - The Impact of Fluid Dynamics on the Regeneration of Automotive Fiber Coil Filters I. Prediction of Soot Distribution T2 - Chemical Engineering & Technology Y1 - 1997 U6 - https://doi.org/10.1002/ceat.270200507 SN - 0930-7516 VL - 20 IS - 5 SP - 317 EP - 325 ER - TY - GEN A1 - Poplawski, Karoline A1 - Lichtenberger, Janine A1 - Keil, Frerich J. A1 - Schnitzlein, Klaus A1 - Amiridis, Michael D. T1 - Catalytic oxidation of 1,2-dichlorobenzene over ABO3-type perovskites T2 - Catalysis Today KW - Dichlorobenzene KW - Oxidation KW - PCDD/ PCDF KW - Perovskites Y1 - 2000 U6 - https://doi.org/10.1016/S0920-5861(00)00434-X SN - 0920-5861 VL - 62 IS - 4 SP - 329 EP - 336 ER - TY - GEN A1 - Buchholz, Ina von A1 - Schnitzlein, Klaus T1 - Experimentelle Bestimmung von VLE-Daten mittels dynamischer Differenzialkalorimetrie T2 - Chemie Ingenieur Technik Y1 - 2007 U6 - https://doi.org/10.1002/cite.200750198 SN - 0009-286X VL - 79 IS - 9 SP - 1474 EP - 1475 ER - TY - CHAP A1 - Schwidder, Sabine A1 - Schnitzlein, Klaus T1 - Analysis of liquid flow distribution and dispersion in trickle bed reactors - experiments and simulation T2 - CAMURE 8 & ISMR 7, Naantali, Finland, May 22-25, 2011 Y1 - 2011 SN - 978-952-12-2586-4 PB - Åbo Akademi University CY - Turku ER - TY - GEN A1 - Schwidder, Sabine A1 - Schnitzlein, Klaus T1 - A new model for the design and analysis of trickle bed reactors T2 - Chemical Engineering Journal KW - Trickle bed KW - Multiscale analysis KW - Multiphase reactor Y1 - 2012 U6 - https://doi.org/10.1016/j.cej.2012.07.054 SN - 1385-8947 IS - 207-208 SP - 758 EP - 765 ER - TY - GEN A1 - Schnitzlein, Klaus T1 - Modeling radial dispersion in terms of the local structure of packed beds. Part II: Discrete modeling approach T2 - Chemical Engineering Science KW - Packed bed KW - Mathematical modeling KW - Chemical reactors KW - Fluid mechanics KW - Transport processes Y1 - 2006 U6 - https://doi.org/10.1016/j.ces.2006.12.060 SN - 0009-2509 VL - 62 IS - 18-20 SP - 4944 EP - 4947 ER - TY - GEN A1 - Muth, Marco A1 - Schmid, Reiner P. A1 - Schnitzlein, Klaus T1 - Ellipsometric study of molecular orientations of Thermomyces lanuginosus lipase at the air-water interface by simultaneous determination of refractive index and thickness T2 - Colloids and Surfaces B: Biointerfaces Y1 - 2016 UR - http://www.sciencedirect.com/science/article/pii/S0927776515303714 U6 - https://doi.org/10.1016/j.colsurfb.2015.12.024 SN - 1873-4367 SN - 0927-7765 VL - 140 SP - 60 EP - 66 ER - TY - CHAP A1 - Schmid, Reiner P. A1 - Muth, Marco A1 - Schnitzlein, Klaus T1 - Adsorptionskinetik der Lipase Thermomyces lanuginosus an fluiden Grenzflächen mittels Ellipsometrie T2 - Tagungsband, GVC-DECHEMA-Vortrags- und Diskussionstagung Bioverfahrenstechnik an Grenzflächen, Potsdam, 30. Mai - 1. Juni 2011 KW - Adsorptionskinetik KW - fluiden Grenzflächen KW - Ellipsometrie Y1 - 2011 SP - 89 EP - 90 PB - DECHEMA CY - Frankfurt, M. ER - TY - GEN A1 - Muth, Marco A1 - Rothkötter, Stefanie A1 - Paprosch, Steven A1 - Schmid, Reiner P. A1 - Schnitzlein, Klaus T1 - Competition of Thermomyces lanuginosus lipase with its hydrolysis products at the oil-water interface T2 - Colloids and Surfaces B: Biointerfaces Y1 - 2017 U6 - https://doi.org/10.1016/j.colsurfb.2016.10.019 SN - 0927-7765 VL - 149 SP - 280 EP - 287 ER - TY - GEN A1 - Schröter, Sandra A1 - Schnitzlein, Klaus T1 - Enzymatic hydrolysis of rapeseed oil by thermomyces lanuginosus lipase: variation of continuous and dispersed phase in a slug flow reactor T2 - Applied Microbiology and Biotechnology N2 - This paper takes a look on the effects of mass transport limitation occurring in hydrolysis of rape seed oil by means of an interfacial activated lipase from Thermomyces lanuginosus. In order to carry out investigations for process optimization, the slug flow reactor was chosen in which a large interfacial area can be generated and the mass transport can be investigated individually for each phase. The choice of the capillary material determines the dispersed and the continuous phase. As shown by computational fluid dynamics simulation, the continuous phase is well mixed due to wall effects. The mixing patterns in the dispersed phase differ due to viscous forces between the phases. It was found that, at the same fluid velocities, the conversion in the glass capillary is higher than in the PTFE capillary. The surface-specific hydrolysis rate is used for comparison purposes, since the properties of the capillary are different. Increasing the velocity, the hydrolysis rate can be considerably increased in comparison to stagnant conditions. Already at a fluid velocity of 1 mm s−1, the hydrolysis rates increased to 2.3-fold in the glass capillary and moreover by a factor of 4 in the PTFE capillary. KW - Thermomyces lanuginosus lipase KW - Rapeseed oil KW - Mass transport CFD simulation KW - Liquid-liquid segmented capillary flow Y1 - 2018 U6 - https://doi.org/10.1007/s00253-018-8902-z SN - 1432-0614 VL - 102 IS - 11 SP - 4799 EP - 4806 ER - TY - CHAP A1 - Schröter, Sandra A1 - Schnitzlein, Klaus T1 - Macrokinetic Analysis of Liquid-Liquid-Interfacial-Reactions in a Slug Flow Reactor T2 - Jahrestreffen Reaktionstechnik 2017, Würzburg, 2017 N2 - Interfacial reactions occur in heterogeneous reaction systems in which two immiscible phases containing the reactants are brought into contact. The catalyst is located at the phase boundary surface, so it is advantageous for high yields to generate a large interfacial area. Microreactors offer a possibility for this, they are characterized by their enhanced mass transfer, which leads to process intensification. Furthermore, here it is possible to optimize processes on a small scale and with little time effort. The fields of application range from reactive extraction of organic compounds over polycondensation to hydrolysis of esters. The slug-flow reactor used in this study is a micro scale capillary in which an aqueous phase and an organic phase are conveyed forming a continuous and a dispersed phase. This results in a high surface-to-volume ratio, which is predestined for the enzymatic reactions at interfaces. In the present study, a lipase from Thermomyces lanuginosus is bound to the interface, it is a water-soluble interface-active enzyme capable of cleaving the ester bond of triglycerides. However, the enzymatic hydrolysis is limited by mass transport and benefits from the accelerated supply and removal of the reaction species to or from the interface. A further influencing factor besides the mass transport is, however, the shear stress at the interface, which has a negative effect on the enzyme activity.1 The aim is to demonstrate these opposing effects and to analyze the macrokinetic, which includes the interactions of chemical reaction (microkinetics) and mass transport. Measurements were carried out at different flow velocities. In addition, the organic phase (rapeseed oil) and the aqueous phase (buffer with enzyme) could be adjusted as the continuous and the disperse phase or vice versa by selecting different capillary materials. As shown in a previous study, different flow profiles will be generated. Finally, the surfacespecific hydrolysis rate was determined from the measured fatty acid concentration and the calculated interfacial area. The oil or water sided flow profiles have an hugh effect on overall hydrolysis rate. So the overall hydrolysis rate increases when mass transfer in oleic phase is enhanced by choosing it as continuous phase, this could even compensate the negative effect of shear stress in aqueous phase.1 Furthermore, the flow profiles in the Slug-Flow Reactor can also be modeled very well in the CFD simulation. So this numerical study serves as an important basis for the explanation of the occuring phenomenons. KW - Liquid Liquid Slug Flow KW - Mass transport limitation KW - Thermomyces lanuginosus Lipase KW - Rapeseed oil Y1 - 2017 U6 - https://doi.org/10.13140/RG.2.2.14159.38564 ER - TY - GEN A1 - Dorneanu, Bogdan A1 - Heinzelmann, Norbert A1 - Schnitzlein, Klaus A1 - Arellano-García, Harvey T1 - A novel approach to modelling trickle bed reactors T2 - Computer Aided Chemical Engineering N2 - In this contribution, the development of a toolbox for the simulation of trickle bed reactors based on a model able to account for the local properties of the liquid and gas flow in a packed bed at particle scale is introduced. The implementation uses a modular and flexible setup, with local liquid distribution considered as a function of the operating conditions and the physical properties of the three phases. Moreover, the impact of the local incomplete wetting on the conversion, as well as the mass transport and kinetics at both particle and reactor scale are accounted for. Furthermore, different particle geometries are considered, and the model is able to reliably predict the performance of the catalytic trickle bed reactors. Y1 - 2022 UR - https://www.sciencedirect.com/science/article/abs/pii/B9780323958790500473?via%3Dihub U6 - https://doi.org/10.1016/B978-0-323-95879-0.50047-3 SN - 1570-7946 VL - 51 SP - 277 EP - 282 ER - TY - GEN A1 - Mappas, Vassileios A1 - Dorneanu, Bogdan A1 - Heinzelmann, Norbert A1 - Schnitzlein, Klaus A1 - Arellano-García, Harvey T1 - A unified modular framework for modeling multiphase reactors T2 - Annual Meeting of Process Engineering and Materials Technology 2024 Y1 - 2024 UR - https://www.researchgate.net/publication/388143505_A_unified_modular_framework_for_modeling_multiphase_reactors ER -