TY - GEN A1 - Volkov, Ilan A1 - Seguro, Luciana A1 - Leion, Elaine P. A1 - Kovács, László A1 - Roggenbuck, Dirk A1 - Schierack, Peter A1 - Gilburd, Boris A1 - Doria, Andrea A1 - Tektonidou, Maria G. A1 - Agmon-Levin, Nancy T1 - Profiles of criteria and non-criteria anti-phospholipid autoantibodies are associated with clinical phenotypes of the antiphospholipid syndrome T2 - Autoimmunity Highlights Y1 - 2020 U6 - https://doi.org/10.1186/s13317-020-00131-3 SN - 2038-3274 SN - 2038-0305 VL - 11 SP - 1 EP - 8 ER - TY - GEN A1 - Ali, Aamir A1 - Kolenda, Rafał A1 - Khan, Muhammad Moman A1 - Weinreich, Jörg A1 - Li, Ganwu A1 - Wieler, Lothar H. A1 - Tedin, Karsten A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - Novel Avian Pathogenic Escherichia coli Genes Responsible for Adhesion to Chicken and Human Cell Lines T2 - Applied and Environmental Microbiology Y1 - 2020 U6 - https://doi.org/10.1128/AEM.01068-20 SN - 1098-5336 VL - 86 IS - 20 ER - TY - GEN A1 - Schierack, Peter A1 - Heiden, Stefan E. A1 - Khan, Muhammad Moman A1 - Nikolaus, Lena A1 - Kolenda, Rafał A1 - Stubbe, Michael A1 - Lkhagvasuren, Davaa A1 - Rödiger, Stefan A1 - Guenther, Sebastian A1 - Schaufler, Katharina T1 - Genomic and Phenotypic Analysis of an ESBL-Producing E. coli ST1159 Clonal Lineage From Wild Birds in Mongolia T2 - Frontiers in Microbiology Y1 - 2020 U6 - https://doi.org/10.3389/fmicb.2020.01699 SN - 1664-302X VL - 11 ER - TY - GEN A1 - Reimann, Ronny A1 - Zeng, Bo A1 - Jakopec, Martin A1 - Burdukiewicz, Michał A1 - Petrick, Ingolf A1 - Schierack, Peter A1 - Rödiger, Stefan T1 - Classification of dead and living microalgae Chlorella vulgaris by bioimage informatics an machine learning T2 - Algal Research Y1 - 2020 U6 - https://doi.org/10.1016/j.algal.2020.101908 SN - 2211-9264 VL - 48 ER - TY - GEN A1 - Roggenbuck, Dirk A1 - Elmont, Emilien A1 - Reinhold, Dirk A1 - Schierack, Peter A1 - Conrad, Karsten A1 - Boucraut, Joseph T1 - Autoimmune Perpheral Neuropathies and Contribution of Antiganglioside/Sulphatide Autoantibody Testing T2 - Mediterranean Jounal of Rheumatology Y1 - 2020 U6 - https://doi.org/10.31138/mjr.31.1.10 SN - 2529-198X VL - 31 IS - 1 SP - 10 EP - 18 ER - TY - GEN A1 - Deutschmann, Claudia A1 - Roggenbuck, Dirk A1 - Schierack, Peter A1 - Rödiger, Stefan T1 - Autoantibody testing by enzyme-linked immunosorbent assay-a case in which the solid phase decides on success and failure T2 - Heliyon Y1 - 2020 U6 - https://doi.org/10.1016/j.heliyon.2020.e03270 SN - 2405-8440 VL - 6 IS - 1 ER - TY - GEN A1 - Schiebel, Juliane A1 - Noack, Jonas A1 - Rödiger, Stefan A1 - Kammel, Anne A1 - Menzel, Friederike A1 - Schwibbert, Karin A1 - Weise, Matthias A1 - Weiss, Romano A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Elimport, Alexey A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - Analysis of three-dimensional biofilms on different material surfaces T2 - Biomaterials Science Y1 - 2020 U6 - https://doi.org/10.1039/D0BM00455C SN - 2047-4849 VL - 8 IS - 12 SP - 3500 EP - 3510 ER - TY - GEN A1 - Liedtke, Victoria A1 - Schröder, Christian A1 - Roggenbuck, Dirk A1 - Weiss, Romano A1 - Stohwasser, Ralf A1 - Schierack, Peter A1 - Rödiger, Stefan A1 - Schenk, Lysann T1 - LEDGF/p75 is required for an efficient DNA damage response T2 - International Journal of Molecular Sciences KW - LEDGF KW - CRISPR/Cas9 KW - DNA damage signaling KW - gH2AX KW - ubiquitination Y1 - 2021 U6 - https://doi.org/10.3390/ijms22115866 VL - 22 IS - 11 SP - 1 EP - 16 ER - TY - GEN A1 - Kolenda, Rafał A1 - Burdukiewicz, Michał A1 - Wimonć, Marcjanna A1 - Aleksandrowicz, Adrianna A1 - Ali, Aamir A1 - Szabo, Istvan A1 - Tedin, Karsten A1 - Bartholdson, Scott J. A1 - Pickhard, Derek A1 - Schierack, Peter T1 - Identification of Natural Mutations Responsible for Altered Infection Phenotypes of Salmonella enterica Clinical Isolates by Using Cell Line Infection Screens T2 - Applied and Environmental Microbiology Y1 - 2021 U6 - https://doi.org/10.1128/AEM.02177-20 SN - 1098-5336 VL - 87 IS - 2 ER - TY - GEN A1 - Comabella, Manual A1 - Deutschmann, Claudia A1 - Midaglia, Luciana A1 - Schierack, Peter A1 - Martínez, Júlia A1 - Roggenbuck, Dirk A1 - Montalban, Xavier T1 - Chitinase 3-like 1 is not a target antigen in patients with multiple sclerosis T2 - Multiple Sclerosis Journal Y1 - 2021 U6 - https://doi.org/10.1177/1352458520980141 SN - 1477-0970 SN - 1352-4585 VL - 27 IS - 9 SP - 1455 EP - 1457 ER - TY - GEN A1 - Schmidt, Jonas A1 - Berghaus, Sandro A1 - Blessing, Frithjof A1 - Wenzel, Folker A1 - Herbeck, Holger A1 - Blessing, Josef A1 - Schierack, Peter A1 - Rödiger, Stefan A1 - Roggenbuck, Dirk T1 - Serological and viral genetic features of patients with COVID-19 in a selected German patient cohort-correlation with disease characteristics T2 - GeroScience Y1 - 2021 U6 - https://doi.org/10.1007/s11357-021-00443-w SN - 2509-2723 SN - 2509-2715 VL - 43 IS - 5 SP - 2249 EP - 2264 ER - TY - GEN A1 - Adefioye, Olusolabomi J. A1 - Weinreich, Jörg A1 - Rödiger, Stefan A1 - Schierack, Peter A1 - Olowe, Olugbenga Adekunle T1 - Phylogenetic Characterization and Multilocus Sequence Typing of Extended-Spectrum Beta Lactamase-Producing Escherichia coli from Food-Producing Animals, Beef, and Humans in Southwest Nigeria T2 - Microbial Drug Resistance Y1 - 2021 U6 - https://doi.org/10.1089/mdr.2019.0397 SN - 1931-8448 SN - 1076-6294 VL - 27 IS - 1 SP - 111 EP - 120 ER - TY - GEN A1 - Hanschmann, Henning A1 - Rödiger, Stefan A1 - Kramer, Toni A1 - Hanschmann, Katrin A1 - Steidle, Michael A1 - Fingerle, Volker A1 - Schmidt, Carsten A1 - Lehmann, Werner A1 - Schierack, Peter T1 - LoopTag FRET Probe System for Multiplex qPCR Detection of Borrelia Species T2 - Life Y1 - 2021 U6 - https://doi.org/10.3390/life11111163 SN - 2075-1729 VL - 11 IS - 11 ER - TY - GEN A1 - Fotang, Chefor A1 - Bröring, Udo A1 - Roos, Christian A1 - Enoguanbhor, Evidence Chinedu A1 - E. Abwe, Ekwoge A1 - Dutton, Paul A1 - Schierack, Peter A1 - Angwafo, Tsi Evaristus A1 - Birkhofer, Klaus T1 - Human activity and forest fragmentation threaten populations of the Nigeria-Cameroon Chimpanzee (Pan troglodytes ellioti) in Western Cameroon T2 - International Journal of Primatology N2 - Increased human activities such as commodity-led deforestation, extension of agriculture, urbanization, and wildfires are major drivers of forest loss worldwide. In Cameroon, these activities cause a loss of suitable primate habitat and could ultimately threaten the survival of chimpanzees (Pan troglodytes). We derived independent estimates of the population size of the Endangered Nigeria–Cameroon chimpanzee (Pan troglodytes ellioti) in Kom-Wum Forest Reserve, Cameroon, and surrounding unprotected forest areas through 1) direct observations, 2) camera trapping, 3) distance sampling, 4) marked nest counts, and 5) standing crop nest counts. In addition, we georeferenced signs of chimpanzee and human activity along line transects. We used a generalized linear mixed model to predict the occurrence of chimpanzees in response to edge length (measured as the perimeter of core forest patches), core area of forest patches (measured as area of forest patches beyond an edge width of 100 m), habitat perforation (measured as the perimeter of nonforested landscape within core forest patches), patch size(measured as area of forest patches), and forest cover. Chimpanzee density estimates ranged from 0.1 (direct observation) to 0.9 (distance sampling) individuals km−2 depending on estimation method with a mean nest group size of 7 ± 5.4 (SD). The mean encounter rate for signs of chimpanzee activity was significantly higher in mature forests (2.3 signs km−1) than in secondary forests (0.3 signs km−1) and above 1000 m elevation (4.0 signs km−1) than below 1000 m (1.0 signs km−1). The mean encounter rate for signs of human activity was significantly higher in secondary (8.0 signs km−1) than in mature forests (0.9 signs km−1). Secondary forests, habitat perforation, and edge length had a significant negative effect on the occurrence of chimpanzee signs. Overall, human activity and forest degradation affected the number of observed chimpanzee signs negatively. Regular antipoaching patrols and reforestation programs in degraded areas could potentially reduce threats to populations of endangered species and may increase suitable habitat area. KW - Bushmeat hunting KW - Core areas KW - Edge length KW - Forest fragmentation KW - Forest perforation KW - Nest counts KW - Mature forest KW - Pan troglodytes ellioti KW - Secondary forest Y1 - 2021 U6 - https://doi.org/10.1007/s10764-020-00191-2 SN - 1573-8604 SN - 0164-0291 VL - 42 IS - 1 SP - 105 EP - 129 ER - TY - GEN A1 - Schmidt, Carsten A1 - Borcherding, Heike A1 - Thiele, Thomas A1 - Schedler, Uwe A1 - Werner, Franziska A1 - Rödiger, Stefan A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - Fluorescence-encoded poly (methyl metharcylate) nanoparticles for a lateral flow assay detecting IgM autoantibodies in rheumatoid arthritis T2 - Analytical biochemistry Y1 - 2021 U6 - https://doi.org/10.1016/journal.ppat.1010118 SN - 1096-0309 VL - Vol. 633 ER - TY - GEN A1 - Emmenegger, Marc A1 - Kumar, Sreedhar Saseendran A1 - Emmenegger, Vishalini A1 - Malinauskas, Tomas A1 - Büttner, Thomas A1 - Rose, Laura A1 - Schierack, Peter A1 - Sprinzl, Martin F. A1 - Sommer, Clemens J. A1 - Lackner, Karl J. A1 - Aguzzi, Adriano A1 - Roggenbuck, Dirk A1 - Frauenknecht, Katrin B. M. T1 - Anti-prothrombin autoantibodies enriched after infection with SARS-CoV-2 and influenced by strength of antibody response against SARS-CoV-2 proteins T2 - PLoS pathogens Y1 - 2021 U6 - https://doi.org/10.1371/journal.ppat.1010118 SN - 1553-7374 VL - 17 IS - 12 ER - TY - GEN A1 - Awan, Asad Bashir A1 - Yan, Aixin A1 - Sarwar, Yasra A1 - Schierack, Peter A1 - Ali, Aamir T1 - Detection of synergistic antimicrobial resistance mechanisms in clinical isolates of Pseudomonas aeruginosa from post-operative wound infections T2 - Applied Microbiology and Biotechnology Y1 - 2021 U6 - https://doi.org/10.1007/s00253-021-11680-6 SN - 1432-0614 VL - 105 IS - 2 SP - 9321 EP - 9332 ER - TY - GEN A1 - Roggenbuck, Johannes J. A1 - Zarske, Grit A1 - Schierack, Peter A1 - Wunderlich, Gerd A1 - Conrad, Karsten A1 - Kotzerke, Joerg A1 - Roggenbuck, Dirk A1 - Zöphel, Klaus T1 - Third generation radioimmunoassay (RIA) for TSH receptor autoantibodies (TRAb) - one step less, similar results? T2 - Nuklearmedizin Y1 - 2021 U6 - https://doi.org/10.1055/a-1277-5972 SN - 0029-5566 VL - 60 IS - 1 SP - 38 EP - 46 ER - TY - GEN A1 - Schmidt, Jonas A1 - Berghaus, Sandro A1 - Blessing, Frithjof A1 - Wenzel, Folker A1 - Herbeck, Holger A1 - Blessing, Josef A1 - Schierack, Peter A1 - Rödiger, Stefan A1 - Roggenbuck, Dirk T1 - A semi-automated, isolation-free, high-throughput SARS-CoV-2 reverse transcriptase (RT) loop-mediated isothermal amplification (LAMP) test T2 - Scientific reports Y1 - 2021 U6 - https://doi.org/10.1038/s41598-021-00827-0 SN - 2045-2322 VL - 11 IS - 1 ER - TY - GEN A1 - Bartlitz, Christin A1 - Kolenda, Rafał A1 - Chilimoniuk, Jarosław A1 - Grzymajlo, Krzysztof A1 - Rödiger, Stefan A1 - Bauerfeind, Rolf A1 - Ali, Aamir A1 - Tchesnokovag, Veronika A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - Adhesion of Enteropathogenic, Enterotoxigenic, and Commensal Escherichia coli to the Major Zymogen Granule Membrane Glyoprotein 2 T2 - Applied abd Environmental Microbiology Y1 - 2022 U6 - https://doi.org/10.1128/aem.02279-21 SN - 1098-5536 VL - 88 IS - 5 ER - TY - GEN A1 - Schmidt, Carsten A1 - Kammel, Anne A1 - Tanner, Julian A. A1 - Kinghorn, Andrew B. A1 - Khan, Muhammad Moman A1 - Lehmann, Werner A1 - Menger, Marcus A1 - Schedler, Uwe A1 - Schierack, Peter A1 - Rödiger, Stefan T1 - A Multiparametic Fluorescence Assay for Screening Aptamer-Protein Interactions Based on Microbeads T2 - Scientific Reports Y1 - 2022 U6 - https://doi.org/10.1038/s41598-022-06817-0 SN - 2045-2322 VL - 12 ER - TY - GEN A1 - Sydow, Katharina A1 - Eger, Elias A1 - Schwabe, Michael A1 - Heiden, Stefan E. A1 - Bohnert, Jürgen A. A1 - Franzenburg, Sören A1 - Jurischka, Christoph A1 - Schierack, Peter A1 - Schaufler, Katharina T1 - Geno- and Phenotypic Characteristics of a Klebsiella pneumoniae ST20 Isolate with Unusual Colony Morphology T2 - Microorganisms N2 - Klebsiella pneumoniae is a common member of the intestinal flora of vertebrates. In addition to opportunistic representatives, hypervirulent (hvKp) and antibiotic-resistant K. pneumoniae (ABR-Kp) occur. While ABR-Kp isolates often cause difficult-to-treat diseases due to limited therapeutic options, hvKp is a pathotype that can infect healthy individuals often leading to recurrent infection. Here, we investigated the clinical K. pneumoniae isolate PBIO3459 obtained from a blood sample, which showed an unusual colony morphology. By combining whole-genome and RNA sequencing with multiple in vitro and in vivo virulence-associated assays, we aimed to define the respective Klebsiella subtype and explore the unusual phenotypic appearance. We demonstrate that PBIO3459 belongs to sequence type (ST)20 and carries no acquired resistance genes, consistent with phenotypic susceptibility tests. In addition, the isolate showed low-level virulence, both at genetic and phenotypic levels. We thus suggest that PBIO3459 is an opportunistic (commensal) K. pneumoniae isolate. Genomic comparison of PBIO3459 with closely related ABR-Kp ST20 isolates revealed that they differed only in resistance genes. Finally, the unusual colony morphology was mainly associated with carbohydrate and amino acid transport and metabolism. In conclusion, our study reveals the characteristics of a Klebsiella sepsis isolate and suggests that opportunistic representatives likely acquire and accumulate antibiotic resistances that subsequently enable their emergence as ABR-Kp pathogens. KW - virulence KW - next-generation sequencing KW - biofilm KW - exopolysaccharides Y1 - 2022 U6 - https://doi.org/10.3390/microorganisms10102063 SN - 2076-2607 VL - 10 IS - 10 ER -