TY - CHAP A1 - Berg, Heinz Peter A1 - Dückershoff, Roland A1 - Lehmann, Mario A1 - Prechavut, Nontavut T1 - Micro Turbo-Fuel-Cell-Technology : Hybrid compact turbo machinery technology and thermodynamic aspects regarding design parameters of a high efficient MGT-SOFC-system T2 - 12th European Conference on Turbomachinery Fluid dynamics & Thermodynamics N2 - The improvement of decentralised energy supply systems has received an important role in the recent years. One option is the combination of SOFC with recuperated MGT. Here, a new strategy for selecting the system parameters, such as the operating temperature of the SOFC, turbine inlet temperature and the pressure ratio of the hybrid system, is presented. By introducing the heat ratio between the heat required to increase the process gas to the SOFC operating temperature and the heat required to raise the SOCF exhaust gas to the TIT, it was found that high efficiency (approx. 68%) is realisable in a compact hybrid system today. Analysis also shows that the HEX-technology is needed to improve the system effectiveness. Also, high recirculation rates with lower TIT can be considered as the future development direction. In addition, a sample configuration of an oil-free MGT rotor unit with high speed foil bearings is presented. KW - MGT-SOFC KW - Brennstoffzellen KW - Mikrogasturbinen KW - Hybrid Y1 - 2017 UR - http://www.euroturbo.eu/paper/ETC2017-266.pdf U6 - https://doi.org/10.29008/ETC2017-266 SP - 1 EP - 12 ER - TY - GEN A1 - Frömmel, Ulrike A1 - Lehmann, Werner A1 - Rödiger, Stefan A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Weinreich, Jörg A1 - Groß, Julia A1 - Roggenbuck, Dirk A1 - Zinke, Olaf A1 - Ansorge, Hermann A1 - Vogel, Steffen A1 - Klemm, Per A1 - Wex, Thomas A1 - Schröder, Christian A1 - Wieler, Lothar H. A1 - Schierack, Peter T1 - Adhesion of human and animal Escherichia coli strains in association with their virulence-associated genes and phylogenetic origins T2 - Applied and environmental microbiology N2 - Intestinal colonization is influenced by the ability of the bacterium to inhabit a niche, which is based on the expression of colonization factors. Escherichia coli carries a broad range of virulence-associated genes (VAGs) which contribute to intestinal (inVAGs) and extraintestinal (exVAGs) infection. Moreover, initial evidence indicates that inVAGs and exVAGs support intestinal colonization. We developed new screening tools to genotypically and phenotypically characterize E. coli isolates originating in humans, domestic pigs, and 17 wild mammal and avian species. We analyzed 317 isolates for the occurrence of 44 VAGs using a novel multiplex PCR microbead assay (MPMA) and for adhesion to four epithelial cell lines using a new adhesion assay. We correlated data for the definition of new adhesion genes. inVAGs were identified only sporadically, particularly in roe deer (Capreolus capreolus) and the European hedgehog ( Erinaceus europaeus). The prevalence of exVAGs depended on isolation from a specific host. Human uropathogenic E. coli isolates carried exVAGs with the highest prevalence, followed by badger (Meles meles) and roe deer isolates. Adhesion was found to be very diverse. Adhesion was specific to cells, host, and tissue, though it was also unspecific. Occurrence of the following VAGs was associated with a higher rate of adhesion to one or more cell lines: afa-dra, daaD, tsh, vat, ibeA, fyuA, mat, sfa-foc, malX, pic, irp2, and papC. In summary, we established new screening methods which enabled us to characterize large numbers of E. coli isolates. We defined reservoirs for potential pathogenic E. coli. We also identified a very broad range of colonization strategies and defined potential new adhesion genes. Y1 - 2013 U6 - https://doi.org/10.1128/AEM.01384-13 SN - 1098-5336 SN - 0099-2240 VL - 79 IS - 19 SP - 5814 EP - 5829 ER - TY - CHAP A1 - Rödiger, Stefan A1 - Schierack, Peter A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Berger, Ingo A1 - Frömmel, Ulrike A1 - Schmidt, Carsten A1 - Ruhland, Mirko A1 - Schimke, Ingolf A1 - Roggenbuck, Dirk A1 - Lehmann, Werner A1 - Schröder, Christian ED - Seitz, Harald ED - Berger, Ingo T1 - A highly versatile microscope imaging technology platform for the multiplex real-time detection of biomolecules and autoimmune antibodies T2 - Molecular diagnostics Y1 - 2013 SN - 978-3-642-37690-0 SN - 978-3-642-37691-7 SP - 35 EP - 74 PB - Springer CY - Berlin [u.a.] ER - TY - GEN A1 - Rödiger, Stefan A1 - Liebsch, Claudia A1 - Schmidt, Carsten A1 - Lehmann, Werner A1 - Resch-Genger, U. A1 - Schedler, Uwe A1 - Schierack, Peter T1 - Nucleic acid detection based on the use of microbeads: a review T2 - Microchimica Acta Y1 - 2014 U6 - https://doi.org/10.1007/s00604-014-1243-4 SN - 0026-3672 SN - 1436-5073 VL - 181 IS - 11-12 SP - 1151 EP - 1168 ER - TY - GEN A1 - Rödiger, Stefan A1 - Lehmann, Werner A1 - Frömmel, Ulrike A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Burdukiewicz, Michał A1 - Schröder, Christian A1 - Dangla, Rémi A1 - Droniou, Magali A1 - Schierack, Peter T1 - The Modi Operandi of the VideoScan Platform for the Detection and Analysis of Nucleic Acids. Life Science Day 2013 & 17. Leibniz Conference of Advanced Science, Freie Universität Berlin, 24.10.2013 Y1 - 2013 UR - https://leibniz-institut.de/Konferenzen/lsd2013/roediger_the_modi_operandi_of_the_videoscan_platform.pdf ER - TY - CHAP A1 - Rödiger, Stefan A1 - Hanschmann, Henning A1 - Steidle, Michael A1 - Schröder, Christian A1 - Schierack, Peter A1 - Lehmann, Werner T1 - Detection of Borrelia, Bordetella and HPV with the LoopTag Real-Time PCR Probe System T2 - International journal of medical microbiology Y1 - 2013 SN - 1618-0607 SN - 1438-4221 N1 - 65. Jahrestagung der Deutschen Gesellschaft für Hygiene und Mikrobiologie e.V. und der Jahrestagung der Deutschen Gesellschaft für Infektiologie (DGI) e.V., Universität Rostock, 22.09. – 25.09.20 13, Rostock VL - 303 IS - Supplement 1 SP - 12 EP - 13 ER - TY - GEN A1 - Liebsch, Claudia A1 - Rödiger, Stefan A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Weinreich, Jörg A1 - Fruth, Angelika A1 - Roggenbuck, Dirk A1 - Lehmann, Werner A1 - Schedler, Uwe A1 - Juretzek, Thomas A1 - Schierack, Peter T1 - Solid-phase microbead array for multiplex O-serotyping of Escherichia coli T2 - Microchimica Acta Y1 - 2017 U6 - https://doi.org/10.1007/s00604-017-2088-4 SN - 0026-3672 SN - 1436-5073 VL - 184 IS - 5 SP - 1405 EP - 1415 ER - TY - GEN A1 - Burdukiewicz, Michał A1 - Spiess, Andrej-Nikolai A1 - Blagodatskikh, Konstantin A. A1 - Lehmann, Werner A1 - Schierack, Peter A1 - Rödiger, Stefan T1 - Algorithms for automated detection of hook effect-bearing amplification curves T2 - Biomolecular Detection and Quantification Y1 - 2018 U6 - https://doi.org/10.1016/j.bdq.2018.08.001 SN - 2214-7535 VL - 16 SP - 1 EP - 4 ER - TY - GEN A1 - Krüger-Genge, Anne A1 - Jung, Friedrich A1 - Küpper, Jan-Heiner A1 - Lehmann, Christian A1 - Franke, Ralf-Peter T1 - Actin type and distribution in erythrocytes T2 - Journal of Cellular Biotechnology N2 - Erythrocytes transport oxygen from the lungs to the tissues. The excess surface area together with the elasticity of the erythrocyte cell membrane provides the flexibility needed to pass through the microvasculature where the oxygen exchange occurs. Although the architecture of the red cell and its membrane-associated cytoskeletal network is known in general, the factors that control the characteristic shape change during echinocyte formation are poorly understood. In this short report we show that in echinocytes a completely reorganized membrane cytoskeleton with a box-like structure of actin filaments prevailed indicating the importance of the actin cytoskeleton during echinocyte formation. KW - Erythrocytes KW - echinocytes KW - submembraneous cytoskeleton KW - actin Y1 - 2018 UR - https://content.iospress.com/articles/journal-of-cellular-biotechnology/jcb179014 U6 - https://doi.org/10.3233/JCB-179014 SN - 2352-3697 SN - 2352-3689 VL - 3 IS - 2 SP - 81 EP - 83 ER - TY - GEN A1 - Dinter, Franziska A1 - Burdukiewicz, Michał A1 - Schierack, Peter A1 - Lehmann, Werner A1 - Nestler, Jörg A1 - Dame, Gregory A1 - Rödiger, Stefan T1 - Simultaneous detection and quantification of DNA and protein biomarkers in spectrum of cardiovascular diseases in a microfluidic microbead chip T2 - Analytical and Bioanalytical Chemistry Y1 - 2019 U6 - https://doi.org/10.1007/s00216-019-02199-x SN - 1618-2650 SN - 1618-2642 VL - 411 IS - 29 SP - 7725 EP - 7735 ER -