TY - GEN A1 - Olowe, Olugbenga Adekunle A1 - Choudhary, S. A1 - Schierack, Peter A1 - Wieler, Lothar H. A1 - Makanjuola, O. B. A1 - Olayemi, A. B. A1 - Anjum, M. T1 - Pathotyping bla CTX-M Escherichia coli from Nigeria T2 - European Journal of Microbiology and Immunology N2 - Background: Escherichia coli have become the enterobacteriaceae species most affected by extended-spectrum β-lactamases (ESBLs) in view of the emergence of CTX-M-type ESBLs. These CTX-M-positive E. coli have been reported in numerous regions worldwide. Virulence determinants of already reported CTX-M-positive E. coli were investigated. Methodology: To gain insights into the mechanism underlying this phenomenon, we assessed serogroup, susceptibility pattern and diversity of virulence profiles within a collection of nine blaCTX-M-positive E. coli strains and their virulent determinant using miniaturized DNA microarray techniques. The nine ESBL-positive E. coli isolates were from eight male and one female patient(s) selected for study based on previous work. Virulence potential was inferred by detection of 63 virulence factor (VF) genes. Results: Four (44.4%) of the 9 E. coli isolates exhibited the same set of core characteristics: serotype O8:Hnt, while all were positive for OXA-1, ciprofloxacin resistance. Five of the isolates exhibited highly similar (91% to 100%) VF profiles. Conclusion: The findings describe a broadly disseminated, blaCTX-M-positive and virulent E. coli serogroup with highly homogeneous virulence genotypes, suggesting recent emergence in this zone. Understanding how this clone has emerged and successfully disseminated within the hospital and community, including across national boundaries, should be a public health priority. Y1 - 2013 U6 - https://doi.org/10.1556/EuJMI.3.2013.2.5 SN - 2062-8633 VL - 3 IS - 2 SP - 120 EP - 125 ER - TY - GEN A1 - Olowe, Olugbenga Adekunle A1 - Adefioye, Olusolabomi J. A1 - Ajayeoba, T. A. A1 - Schiebel, Juliane A1 - Weinreich, Jörg A1 - Ali, Aamir A1 - Burdukiewicz, Michał A1 - Rödiger, Stefan A1 - Schierack, Peter T1 - Phylogenetic grouping and biofilm formation of Multidrug Resistant Escherichia coli Isolates from Humans, Animals and Food products in South-west Nigeria T2 - Scientific African Y1 - 2019 U6 - https://doi.org/10.1016/j.sciaf.2019.e00158 SN - 2468-2276 VL - 6 ER - TY - GEN A1 - Adefioye, Olusolabomi J. A1 - Weinreich, Jörg A1 - Rödiger, Stefan A1 - Schierack, Peter A1 - Olowe, Olugbenga Adekunle T1 - Phylogenetic Characterization and Multilocus Sequence Typing of Extended-Spectrum Beta Lactamase-Producing Escherichia coli from Food-Producing Animals, Beef, and Humans in Southwest Nigeria T2 - Microbial Drug Resistance Y1 - 2021 U6 - https://doi.org/10.1089/mdr.2019.0397 SN - 1931-8448 SN - 1076-6294 VL - 27 IS - 1 SP - 111 EP - 120 ER - TY - GEN A1 - Khan, Muhammad Moman A1 - Ali, Aamir A1 - Kolenda, Rafał A1 - Olowe, Olugbenga Adekunle A1 - Weinreich, Jörg A1 - Li, Ganwu A1 - Schierack, Peter T1 - The role of AJB35136 and fdtA genes in biofilm formation by avian pathogenic Escherichia coli T2 - BMC Veterinary Research Y1 - 2023 U6 - https://doi.org/10.1186/s12917-023-03672-7 SN - 1746-6148 VL - 19 ER -