TY - GEN A1 - Schmidt, Juliana J. A1 - Schmidt, Guilherme J. A1 - Tolentino, Julio C. A1 - Simoes, Eunice N. A1 - Obongo, Angela A1 - Tolentino, Yolanda A1 - Coelho, Francisco A. A1 - Landesmann, Maria C. P. P. A1 - Fonseca, Lea M. B. A1 - Lacerda, Glenda C. B. A1 - Schmidt, Sergio L. T1 - A serial SPECT-CT study in a celiac disease patient with cerebellar ataxia and psychiatric symptoms T2 - Neurological sciences N2 - Celiac disease (CD) is an immune-mediated systemic disorder triggered by gluten and related prolamins in genetically predisposed individuals. Here, we described a case of a 31-year-old Caucasian woman who exhibited cerebellar and psychiatric dysfunctions. The patient underwent single-photon emission computed tomography (SPECT-CT) before and after a gluten-free diet (GFD). There was an improvement in cerebellar perfusion accompanied by a remission of cerebellar manifestations. The maintenance of the psychiatric manifestations was related to the persistence of the hypoperfusion in the frontal lobes. The patient's psychiatric symptoms did not change after 4 months under a GFD in the hospital. To our knowledge, this is the first case that shows the relationship between improvement in cerebellar perfusion and remission of cerebellar clinical manifestations in a CD patient under a GFD. KW - Celiac disease KW - Cerebellar perfusion KW - Cerebellum KW - SPECT-CT Y1 - 2021 UR - https://pubmed.ncbi.nlm.nih.gov/33230758/ U6 - https://doi.org/10.1007/s10072-020-04908-2 SN - 1590-3478 VL - 42 SP - 1545 EP - 1548 ER -