TY - GEN A1 - Sidorczuk, Katarzyna A1 - Burdukiewicz, Michał A1 - Cerk, Klara A1 - Fritscher, Joachim A1 - Kingsley, Robert A. A1 - Schierack, Peter A1 - Hildebrand, Falk A1 - Kolenda, Rafał T1 - AdhesiomeR: a tool for Escherichia coli adhesin classification and analysis T2 - BMC Genomics N2 - AbstractAdhesins are crucial factors in the virulence of bacterial pathogens such as Escherichia coli. However, to date no resources have been dedicated to the detailed analysis of E. coli adhesins. Here, we provide adhesiomeR software that enables characterization of the complete adhesin repertoire, termed the adhesiome. AdhesiomeR incorporates the most comprehensive database of E. coli adhesins and facilitates an extensive analysis of adhesiome. We demonstrate that adhesiomeR achieves 98% accuracy when compared with experimental analyses. Based on analysis of 15,000 E. coli genomes, we define novel adhesiome profiles and clusters, providing a nomenclature for a unified comparison of E. coli adhesiomes. Y1 - 2024 U6 - https://doi.org/10.1186/s12864-024-10525-6 SN - 1471-2164 VL - 25 IS - 1 SP - 1 EP - 10 PB - Springer Science and Business Media LLC ER -