TY - GEN A1 - Schöberl, Florian A1 - Irving, Stephanie A1 - Pradhan, Cauchy A1 - Bardins, Stanislav A1 - Trapp, Christoph A1 - Schneider, Erich A1 - Kugler, Günter A1 - Bartenstein, Peter A1 - Dietrich, Marianne A1 - Brandt, Thomas A1 - Zwergal, Andreas T1 - Prolonged allocentric navigation deficits indicate hippocampal damage in TGA T2 - Neurology : official journal of the American Academy of Neurology N2 - Objective To investigate long-term recovery of allocentric and egocentric spatial orientation as a sensitive marker for hippocampal and extrahippocampal network function in transient global amnesia (TGA). Methods A group of 18 patients with TGA performed an established real-space navigation paradigm, requiring allo- and egocentric spatial orientation abilities, 3 days (postacute stage) and 3 months (follow-up) after symptom onset. Visual exploration behavior and navigation strategy were documented by a gaze-controlled, head-fixed camera. Allo- and egocentric spatial orientation performance was compared to that of 12 age-matched healthy controls. Navigation-induced brain activations were measured using [18F]-fluorodeoxyglucose-PET in a subgroup of 8 patients in the postacute stage and compared to those of the controls. Results In the postacute stage, the patients navigated worse and had higher error rates than controls in allocentric (p = 0.002), but not in egocentric, route planning (p = 0.30), despite complete recovery of verbal (p = 0.58) and figural memory (p = 0.11). Until follow-up, allocentric navigation deficits improved, but higher error rates and reduced use of shortcuts persisted (p < 0.0001). Patients still exhibited relatively more fixations of unique landmarks during follow-up (p = 0.05). PET measurements during the postacute stage showed increased navigation-induced brain activations in the right hippocampus, bilateral retrosplenial, parietal, and mesiofrontal cortices, and cerebellar dentate nucleus in patients compared to controls (p < 0.005). Conclusions Patients with TGA show selective and prolonged deficits of allocentric spatial orientation. Activations in right hippocampal and extrahippocampal hubs of the cerebral navigation network functionally substitute for the deficit in creating and updating the internal cognitive map in TGA. Y1 - 2019 UR - https://n.neurology.org/content/92/3/e234/tab-article-info U6 - https://doi.org/10.1212/WNL.0000000000006779 SN - 0028-3878 SN - 1526-632X VL - 92 IS - 3 SP - e234 EP - e243 ER - TY - GEN A1 - Bonhage, Alexander A1 - Hirsch, Florian A1 - Raab, Thomas A1 - Schneider, Anna A1 - Raab, Alexandra A1 - Ouimet, William T1 - Characteristics of small anthropogenic landforms resulting from historical charcoal production in western Connecticut, USA T2 - Catena Y1 - 2020 U6 - https://doi.org/10.1016/j.catena.2020.104896 SN - 0341-8162 VL - 195 ER - TY - GEN A1 - Schneider, Anna A1 - Hirsch, Florian A1 - Bonhage, Alexander A1 - Raab, Alexandra A1 - Raab, Thomas T1 - The soil moisture regime of charcoal-enriched land use legacy sites T2 - Geoderma Y1 - 2020 U6 - https://doi.org/10.1016/j.geoderma.2020.114241 SN - 0016-7061 VL - 366 ER - TY - GEN A1 - Schneider, Anna A1 - Bonhage, Alexander A1 - Raab, Alexandra A1 - Hirsch, Florian A1 - Raab, Thomas T1 - Large‐scale mapping of anthropogenic relief features—legacies of past forest use in two historical charcoal production areas in Germany T2 - Geoarchaeology Y1 - 2020 U6 - https://doi.org/10.1002/gea.21782 SN - 1520-6548 SN - 0883-6353 VL - 35 IS - 4 SP - 545 EP - 561 ER - TY - GEN A1 - Hirsch, Florian A1 - Schneider, Anna A1 - Bonhage, Alexander A1 - Raab, Alexandra A1 - Drohan, Patrick J. A1 - Raab, Thomas T1 - An initiative for a morphologic‐genetic catalog of relict charcoal hearths from Central Europe T2 - Geoarchaeology Y1 - 2020 U6 - https://doi.org/10.1002/gea.21799 SN - 1520-6548 SN - 0883-6353 VL - 35 IS - 6 SP - 974 EP - 983 ER - TY - GEN A1 - Bonhage, Alexander A1 - Hirsch, Florian A1 - Raab, Thomas A1 - Schneider, Anna A1 - Raab, Alexandra A1 - Ouimet, William T1 - Stratigraphy and shape of relict charcoal hearths in Connecticut, USA T2 - Anthropogenetische Geomorphologie - Geomorophologie im Anthropozän : Virtuelle Jahrestagung des Arbeitskreises für Geomorphologie 2020, 28./29. September 2020, BTU Cottbus - Senftenberg KW - Anthropogenetische Geomorphologie; Anthropozän; BTU; Geopedologie Anthropocene; Anthropogenic geomorphology; Geopedology Y1 - 2020 U6 - https://doi.org/10.26127/BTUOpen-5363 SN - 2196-4122 SP - 29 CY - Cottbus ER - TY - GEN A1 - Raab, Thomas A1 - Raab, Alexandra A1 - Hirsch, Florian A1 - Bonhage, Alexander A1 - Schneider, Anna T1 - Fingerprints from past charcoal burning - lessons learned and future perspective studying Relict Charcoal Hearths (RCH) T2 - EGU General Assembly 2020, Online | 4–8 May 2020 Y1 - 2020 U6 - https://doi.org/https://doi.org/10.5194/egusphere-egu2020-2949 ER - TY - GEN A1 - Schneider, Anna A1 - Hirsch, Florian A1 - Bonhage, Alexander A1 - Raab, Alexandra A1 - Raab, Thomas T1 - The temperature and moisture regime of charcoal-enriched land use legacy soils T2 - EGU General Assembly 2020 Y1 - 2020 U6 - https://doi.org/https://doi.org/10.5194/egusphere-egu2020-2339 ER - TY - GEN A1 - Schneider, Anna A1 - Hirsch, Florian A1 - Raab, Alexandra A1 - Bonhage, Alexander A1 - Raab, Thomas T1 - Relikte historischer Kohlenmeier ini der Oberpfalz - Verbreitung und Erhaltung in Abhängigkeit vom Naturraum T2 - Beiträge zur Archäologie in der Oberpfalz und in Regensburg Y1 - 2020 SN - 1617-4461 IS - 13 SP - 531 EP - 546 ER - TY - GEN A1 - Schneider, Anna A1 - Bonhage, Alexander A1 - Hirsch, Florian A1 - Raab, Alexandra A1 - Raab, Thomas T1 - Accumulation patterns of soil organic matter in forests as a legacy of historical charcoal burning T2 - EGU General Assembly 2021 Y1 - 2021 U6 - https://doi.org/10.5194/egusphere-egu21-5161 ER -