TY - GEN A1 - Buchanan, Erin M. A1 - Lewis, Savannah C. A1 - Paris, Bastien A1 - Forscher, Patrick S. A1 - Pavlacic, Jeffrey M. A1 - Beshears, Julie E. A1 - Drexler, Shira Meir A1 - Gourdon-Kanhukamwe, Amélie A1 - Mallik, Peter R A1 - Silan, Miguel Alejandro A. A1 - Miller, Jeremy K. A1 - IJzerman, Hans A1 - Moshontz, Hannah A1 - Beaudry, Jennifer L. A1 - Suchow, Jordan W. A1 - Chartier, Christopher R. A1 - Coles, Nicholas A. A1 - Sharifian, MohammadHasan A1 - Todsen, Anna Louise A1 - Levitan, Carmel A. A1 - Azevedo, Flávio A1 - Legate, Nicole A1 - Heller, Blake A1 - Rothman, Alexander J. A1 - Dorison, Charles A. A1 - Gill, Brian P. A1 - Wang, Ke A1 - Rees, Vaughan W. A1 - Gibbs, Nancy A1 - Goldenberg, Amit A1 - Thi Nguyen, Thuy-vy A1 - Gross, James J. A1 - Kaminski, Gwenaêl A1 - von Bastian, Claudia C. A1 - Paruzel-Czachura, Mariola A1 - Mosannenzadeh, Farnaz A1 - Azouaghe, Soufian A1 - Bran, Alexandre A1 - Ruiz-Fernandez, Susana A1 - Santos, Anabela Caetano A1 - Reggev, Niv A1 - Zickfeld, Janis H. A1 - Akkas, Handan A1 - Pantazi, Myrto A1 - Ropovik, Ivan A1 - Korbmacher, Max A1 - Arriaga, Patrícia A1 - Gjoneska, Biljana A1 - Warmelink, Lara A1 - Alves, Sara G. A1 - de Holanda Coelho, Gabriel Lins A1 - Stieger, Stefan A1 - Schei, Vidar A1 - Hanel, Paul H. P. A1 - Szaszi, Barnabas A1 - Fedotov, Maksim A1 - Antfolk, Jan A1 - Marcu, Gabriela-Mariana A1 - Schrötter, Jana A1 - Kunst, Jonas R. A1 - Geiger, Sandra J. A1 - Adetula, Adeyemi A1 - Kocalar, Halil Emre A1 - Kielińska, Julita A1 - Kačmár, Pavol A1 - Bokkour, Ahmed A1 - Galindo-Caballero, Oscar J. A1 - Djamai, Ikhlas A1 - Pöntinen, Sara Johanna A1 - AGESIN, Bamikole Emmanuel A1 - Jernsäther, Teodor A1 - Urooj, Anum A1 - Rachev, Nikolay R. A1 - Koptjevskaja-Tamm, Maria A1 - Kurfalı, Murathan A1 - Pit, Ilse L. A1 - Li, Ranran A1 - Çoksan, Sami A1 - Dubrov, Dmitrii A1 - Paltrow, Tamar Elise A1 - Baník, Gabriel A1 - Korobova, Tatiana A1 - Studzinska, Anna A1 - Jiang, Xiaoming A1 - Aruta, John Jamir Benzon R. A1 - Vintr, Jáchym A1 - Chiu, Faith A1 - Kaliska, Lada A1 - Berkessel, Jana B. A1 - Tümer, Murat A1 - Morales-Izquierdo, Sara A1 - Chuan-Peng, Hu A1 - Vezirian, Kevin A1 - Rosa, Anna Dalla A1 - Bialobrzeska, Olga A1 - Vasilev, Martin R. A1 - Beitner, Julia A1 - Kácha, Ondřej A1 - Žuro, Barbara A1 - Westerlund, Minja A1 - Nedelcheva-Datsova, Mina A1 - Findor, Andrej A1 - Krupić, Dajana A1 - Kowal, Marta A1 - Askelund, Adrian Dahl A1 - Pourafshari, Razieh A1 - Đorđević, Jasna Milošević A1 - Schmidt, Nadya-Daniela A1 - Baklanova, Ekaterina A1 - Szala, Anna A1 - Zakharov, Ilya A1 - Vranka, Marek A. A1 - Ihaya, Keiko A1 - Grano, Caterina A1 - Cellini, Nicola A1 - Białek, Michał A1 - Anton-Boicuk, Lisa A1 - Dalgar, Ilker A1 - Adıgüzel, Arca A1 - Verharen, Jeroen P. H. A1 - Maturan, Princess Lovella G. A1 - Kassianos, Angelos P. A1 - Oliveira, Raquel A1 - Čadek, Martin A1 - Adoric, Vera Cubela A1 - Özdoğru, Asil Ali A1 - Sverdrup, Therese E. A1 - Aczel, Balazs A1 - Zambrano, Danilo A1 - Ahmed, Afroja A1 - Tamnes, Christian K. A1 - Yamada, Yuki A1 - Volz, Leonhard A1 - Sunami, Naoyuki A1 - Suter, Lilian A1 - Vieira, Luc A1 - Groyecka-Bernard, Agata A1 - Kamburidis, Julia Arhondis A1 - Reips, Ulf-Dietrich A1 - Harutyunyan, Mikayel A1 - Adetula, Gabriel Agboola A1 - Allred, Tara Bulut A1 - Barzykowski, Krystian A1 - Antazo, Benedict G A1 - Zsido, Andras N. A1 - Šakan, Dušana Dušan A1 - Cyrus-Lai, Wilson A1 - Ahlgren, Lina Pernilla A1 - Hruška, Matej A1 - Vega, Diego A1 - Manunta, Efisio A1 - Mokady, Aviv A1 - Capizzi, Mariagrazia A1 - Martončik, Marcel A1 - Say, Nicolas A1 - Filip, Katarzyna A1 - Vilar, Roosevelt A1 - Staniaszek, Karolina A1 - Vdovic, Milica A1 - Adamkovic, Matus A1 - Johannes, Niklas A1 - Hajdu, Nandor A1 - Cohen, Noga A1 - Overkott, Clara A1 - Krupić, Dino A1 - Hubena, Barbora A1 - Nilsonne, Gustav A1 - Mioni, Giovanna A1 - Solorzano, Claudio Singh A1 - Ishii, Tatsunori A1 - Chen, Zhang A1 - Kushnir, Elizaveta A1 - Karaarslan, Cemre A1 - Ribeiro, Rafael R. A1 - Khaoudi, Ahmed A1 - Kossowska, Małgorzata A1 - Bavolar, Jozef A1 - Hoyer, Karlijn A1 - Roczniewska, Marta A1 - Karababa, Alper A1 - Becker, Maja A1 - Monteiro, Renan P. A1 - Kunisato, Yoshihiko A1 - Metin-Orta, Irem A1 - Adamus, Sylwia A1 - Kozma, Luca A1 - Czarnek, Gabriela A1 - Domurat, Artur A1 - Štrukelj, Eva A1 - Alvarez, Daniela Serrato A1 - Parzuchowski, Michal A1 - Massoni, Sébastien A1 - Czamanski-Cohen, Johanna A1 - Pronizius, Ekaterina A1 - Muchembled, Fany A1 - van Schie, Kevin A1 - Saçaklı, Aslı A1 - Hristova, Evgeniya A1 - Kuzminska, Anna O. A1 - Charyate, Abdelilah A1 - Bijlstra, Gijsbert A1 - Afhami, Reza A1 - Majeed, Nadyanna M. A1 - Musser, Erica D. A1 - Sirota, Miroslav A1 - Ross, Robert M. A1 - Yeung, Siu Kit A1 - Papadatou-Pastou, Marietta A1 - Foroni, Francesco A1 - Almeida, Inês A. T. A1 - Grigoryev, Dmitry A1 - Lewis, David M. G. A1 - Holford, Dawn L. A1 - Janssen, Steve M. J. A1 - Tatachari, Srinivasan A1 - Batres, Carlota A1 - Olofsson, Jonas K. A1 - Daches, Shimrit A1 - Belaus, Anabel A1 - Pfuhl, Gerit A1 - Corral-Frias, Nadia Sarai A1 - Sousa, Daniela A1 - Röer, Jan Philipp A1 - Isager, Peder Mortvedt A1 - Godbersen, Hendrik A1 - Walczak, Radoslaw B. A1 - Van Doren, Natalia A1 - Ren, Dongning A1 - Gill, Tripat A1 - Voracek, Martin A1 - DeBruine, Lisa M. A1 - Anne, Michele A1 - Očovaj, Sanja Batić A1 - Thomas, Andrew G. A1 - Arvanitis, Alexios A1 - Ostermann, Thomas A1 - Wolfe, Kelly A1 - Arinze, Nwadiogo Chisom A1 - Bundt, Carsten A1 - Lamm, Claus A1 - Calin-Jageman, Robert J A1 - Davis, William E. A1 - Karekla, Maria A1 - Zorjan, Saša A1 - Jaremka, Lisa M. A1 - Uttley, Jim A1 - Hricova, Monika A1 - Koehn, Monica A A1 - Kiselnikova, Natalia A1 - Bai, Hui A1 - Krafnick, Anthony J. A1 - Balci, Busra Bahar A1 - Ballantyne, Tonia A1 - Lins, Samuel A1 - Vally, Zahir A1 - Esteban-Serna, Celia A1 - Schmidt, Kathleen A1 - Macapagal, Paulo Manuel L. A1 - Szwed, Paulina A1 - Zdybek, Przemysław Marcin A1 - Moreau, David A1 - Collins, W. Matthew A1 - Joy-Gaba, Jennifer A. A1 - Vilares, Iris A1 - Tran, Ulrich S. A1 - Boudesseul, Jordane A1 - Albayrak-Aydemir, Nihan A1 - Dixson, Barnaby James Wyld A1 - Perillo, Jennifer T A1 - Ferreira, Ana A1 - Westgate, Erin C. A1 - Aberson, Christopher L. A1 - Arinze, Azuka Ikechukwu A1 - Jaeger, Bastian A1 - Butt, Muhammad Mussaffa A1 - Silva, Jaime R. A1 - Storage, Daniel Shafik A1 - Janak, Allison P A1 - Jiménez-Leal, William A1 - Soto, Jose A. A1 - Sorokowska, Agnieszka A1 - McCarthy, Randy A1 - Tullett, Alexa M A1 - Frias-Armenta, Martha A1 - Ribeiro, Matheus Fernando Felix A1 - Hartanto, Andree A1 - Forbes, Paul A. G. A1 - Willis, Megan L. A1 - del Carmen Tejada R, María A1 - Torres, Adriana Julieth Olaya A1 - Stephen, Ian D A1 - Vaidis, David C. A1 - de la Rosa-Gómez, Anabel A1 - Yu, Karen A1 - Sutherland, Clare A. M. A1 - Manavalan, Mathi A1 - Behzadnia, Behzad A1 - Urban, Jan A1 - Baskin, Ernest A1 - McFall, Joseph P. A1 - Ogbonnaya, Chisom Esther A1 - Fu, Cynthia H. Y. A1 - Rahal, Rima-Maria A1 - Ndukaihe, Izuchukwu L. G. A1 - Hostler, Thomas J. A1 - Kappes, Heather Barry A1 - Sorokowski, Piotr A1 - Khosla, Meetu A1 - Lazarevic, Ljiljana B. A1 - Eudave, Luis A1 - Vilsmeier, Johannes K. A1 - Luis, Elkin O. A1 - Muda, Rafał A1 - Agadullina, Elena A1 - Cárcamo, Rodrigo A. A1 - Reeck, Crystal A1 - Anjum, Gulnaz A1 - Venegas, Mónica Camila Toro A1 - Misiak, Michal A1 - Ryan, Richard M. A1 - Nock, Nora L. A1 - Travaglino, Giovanni A. A1 - Mensink, Michael C. A1 - Feldman, Gilad A1 - Wichman, Aaron L. A1 - Chou, Weilun A1 - Ziano, Ignazio A1 - Seehuus, Martin A1 - Chopik, William J. A1 - Kung, Franki Y. H. A1 - Carpentier, Joelle A1 - Vaughn, Leigh Ann A1 - Du, Hongfei A1 - Xiao, Qinyu A1 - Lima, Tiago J. S. A1 - Noone, Chris A1 - Onie, Sandersan A1 - Verbruggen, Frederick A1 - Radtke, Theda A1 - Primbs, Maximilian A. T1 - The psychological science accelerator’s COVID-19 rapid-response dataset T2 - Scientific Data Y1 - 2023 U6 - https://doi.org/10.1038/s41597-022-01811-7 SN - 2052-4463 VL - 10 IS - 1 SP - 1 EP - 15 PB - Springer Science and Business Media LLC ER - TY - GEN A1 - Martinez, Angel T. A1 - Ruiz-Duenas, Francisco J. A1 - Camarero, Susana A1 - Serrano, Ana A1 - Linde, Dolores A1 - Lund, Henrik A1 - Vind, Jesper A1 - Tovborg, Morton A1 - Herold-Majumdar, Owik M. A1 - Hofrichter, Martin A1 - Liers, Christiane A1 - Ullrich, René A1 - Scheibner, Katrin A1 - Sannia, Giovanni A1 - Piscitelli, Alessandra A1 - Sener, Mehmet E. A1 - Kilic, Sibel A1 - Berkel, Willem J. H. van A1 - Guallar, Víctor A1 - Lucas, Maria Fátima A1 - Zuhse, Ralf A1 - Ludwig, Roland A1 - Hollmann, Frank A1 - Fernández-Fueyo, Elena A1 - Record, Eric A1 - Faulds, Craig B. A1 - Tortajada, Marta A1 - Winckelmann, Ib A1 - Rasmussen, Jo-Anne A1 - Gelo-Pujic, Mirjana A1 - Gutiérrez, Ana A1 - Rio, José C. del A1 - Rencoret, Jorge A1 - Alcalde, Miguel T1 - Oxidoreductases on their way to industrial biotransformations T2 - Biotechnology Advances N2 - Fungi produce heme-containing peroxidases and peroxygenases, flavin-containing oxidases and dehydrogenases, and different copper-containing oxidoreductases involved in the biodegradation of lignin and other recalcitrant compounds. Heme peroxidases comprise the classical ligninolytic peroxidases and the new dye-decolorizing peroxidases, while heme peroxygenases belong to a still largely unexplored superfamily of heme-thiolate proteins. Nevertheless, basidiomycete unspecific peroxygenases have the highest biotechnological interest due to their ability to catalyze a variety of regio- and stereo-selective monooxygenation reactions with H2O2 as the source of oxygen and final electron acceptor. Flavo-oxidases are involved in both lignin and cellulose decay generating H2O2 that activates peroxidases and generates hydroxyl radical. The group of copper oxidoreductases also includes other H2O2 generating enzymes - copper-radical oxidases - together with classical laccases that are the oxidoreductases with the largest number of reported applications to date. However, the recently described lytic polysaccharide monooxygenases have attracted the highest attention among copper oxidoreductases, since they are capable of oxidatively breaking down crystalline cellulose, the disintegration of which is still a major bottleneck in lignocellulose biorefineries, along with lignin degradation. Interestingly, some flavin-containing dehydrogenases also play a key role in cellulose breakdown by directly/indirectly “fueling” electrons for polysaccharide monooxygenase activation. Many of the above oxidoreductases have been engineered, combining rational and computational design with directed evolution, to attain the selectivity, catalytic efficiency and stability properties required for their industrial utilization. Indeed, using ad hoc software and current computational capabilities, it is now possible to predict substrate access to the active site in biophysical simulations, and electron transfer efficiency in biochemical simulations, reducing in orders of magnitude the time of experimental work in oxidoreductase screening and engineering. What has been set out above is illustrated by a series of remarkable oxyfunctionalization and oxidation reactions developed in the frame of an intersectorial and multidisciplinary European RTD project. The optimized reactions include enzymatic synthesis of 1-naphthol, 25-hydroxyvitamin D3, drug metabolites, furandicarboxylic acid, indigo and other dyes, and conductive polyaniline, terminal oxygenation of alkanes, biomass delignification and lignin oxidation, among others. These successful case stories demonstrate the unexploited potential of oxidoreductases in medium and large-scale biotransformations. KW - Peroxygenase KW - Biotechnology Y1 - 2017 U6 - https://doi.org/10.1016/j.biotechadv.2017.06.003 SN - 1873-1899 SN - 0734-9750 VL - 35 IS - 6 SP - 815 EP - 831 ER - TY - GEN A1 - Schlipf, Jon A1 - Martin, Elena A1 - Stchakovsky, Michel A1 - Benedetti, Alessandro A1 - Fischer, Inga Anita A1 - Schulze, Jörg A1 - Chiussi, Stefano T1 - Ellipsometric analysis of concentration gradients induced in semiconductor crystals by pulsed laser induced epitaxy T2 - Journal of Vacuum Science & Technology B Y1 - 2019 U6 - https://doi.org/10.1116/1.5122777 SN - 2166-2754 VL - 37 IS - 6 ER -