TY - GEN A1 - Nixdorf, Brigitte A1 - Rücker, Jacqueline A1 - Dolman, Andrew M. A1 - Wiedner, Claudia A1 - Hilt, Sabine A1 - Kasprzak, Peter A1 - Köhler, Antje A1 - Weyer, Klaus van de A1 - Sandrock, Stephan A1 - Scharf, Eva-Maria A1 - Willmitzer, Hartmut T1 - Prozessverständnis als Grundlage für die Gewässerbewirtschaftung – Fallbeispiele für Limitation, Konkurrenz, Gewässerstruktur und Nahrungsnetzsteuerung T2 - Korrespondenz Wasserwirtschaft KW - Gewässerbewirtschaftung Y1 - 2013 SN - 1865-9926 VL - 6 IS - 12 SP - 693 EP - 701 ER - TY - PAT A1 - Narra, Satyanarayana A1 - Ay, Peter A1 - Glaser, Claudia T1 - Vorrichtung und Verfahren zur Agglomeration der Ablauge eines Cellulosegewinnungsprozesses Y1 - 2013 ER - TY - PAT A1 - Narra, Satyanarayana A1 - Ay, Peter A1 - Glaser, Claudia A1 - Logsch, Florian T1 - Verfahren zur Herstellung von wasserunlöslichen Lignin-Agglomeraten Y1 - 2012 ER - TY - CHAP A1 - Narra, Satyanarayana A1 - Glaser, Claudia A1 - Ay, Peter T1 - Abrasion and strength of biomass pellets as main mechanical stability characteristics T2 - 19th European Biomass Conference and Exhibition, proceedings, ICC Berlin International Congress Center Berlin, Germany, conference 6 - 10 June 2011 Y1 - 2011 SN - 978-88-89407-55-7 PB - ETA-Florence Renewable Energies CY - Florence ER - TY - CHAP A1 - Narra, Satyanarayana A1 - Glaser, Claudia A1 - Gusovius, Hans-Jörg A1 - Ay, Peter T1 - Comparison of grinding and liberation processes for stalky biomass materials as a prerequisite for production of energy pellets with high calorific value T2 - XXV International Mineral Processing Congress, IMPC 2010, "Smarter processing for the future", Brisbane, Australia 6-10 September 2010, congress proceedings Y1 - 2010 SN - 978-1-921522-28-4 PB - AusIMM CY - Carlton South, Australia ER - TY - CHAP A1 - Narra, Satyanarayana A1 - Glaser, Claudia A1 - Gusovius, Hans-Jörg A1 - Ay, Peter T1 - Pelletisation of cereal straws as a source of energy after specific communition processes T2 - 18th European Biomass Conference and Exhibition, proceedings of the international conference held in Lyon, France, 3 - 7 May 2010 Y1 - 2010 SN - 978-88-89407-56-5 PB - ETA-Florence Renewable Energies CY - Florence ER - TY - GEN A1 - Narra, Satyanarayana A1 - Tao, Yonggui A1 - Glaser, Claudia A1 - Gusovius, Hans-Jörg A1 - Ay, Peter T1 - Increasing the calorific value of Rye straw pellets with biogenous and fossil additives T2 - Energy and Fuels Y1 - 2010 SN - 0887-0624 VL - 24 IS - 9 SP - 5228 EP - 5234 ER - TY - RPRT A1 - Narra, Satyanarayana A1 - Ay, Peter A1 - Markowski, Jens A1 - Glaser, Claudia T1 - Grundlagenuntersuchungen: Innovative Makroverkapselung von Gärresten Y1 - 2014 UR - http://www.fnr-server.de/ftp/pdf/berichte/22402712.pdf PB - BTU, LS Aufbereitungstechnik CY - Cottbus ER - TY - CHAP A1 - Narra, Satyanarayana A1 - Logsch, Florian A1 - Glaser, Claudia A1 - Ay, Peter A1 - Döhling, Frank A1 - Leistner, Diana A1 - Strube, Dieter ED - Thrän, Daniela ED - Pfeiffer, Diana T1 - LignoBioFuel : Entwicklung eines Verfahrens zur Herstellung von stofflich und energetisch nutzbaren Bioagglomeraten auf der Basis von Lignin T2 - Effizient, umweltverträglich, dezentral - neue Konzepte für die Nutzung von biogenen Festbrennstoffen, Bd. 2 Y1 - 2014 SP - 85 EP - 99 PB - DBFZ, Dt. Biomasseforschungszentrum CY - Leipzig ER - TY - CHAP A1 - Narra, Satyanarayana A1 - Logsch, Florian A1 - Glaser, Claudia A1 - Ay, Peter ED - Thrän, Daniela ED - Pfeiffer, Diana T1 - Erzeugung von Bioagglomeraten auf der Basis ligninhaltiger Ablaugen der Papier- und Zellstoffindustrie T2 - Effizient, umweltverträglich, dezentral - neue Konzepte für die Nutzung von biogenen Festbrennstoffen, Bd. 2 Y1 - 2013 SP - 247 EP - 264 PB - DBFZ, Dt. Biomasseforschungszentrum CY - Leipzig ER - TY - CHAP A1 - Narra, Satyanarayana A1 - Glaser, Claudia A1 - Gusovius, Hans-Jörg A1 - Stollberg, Christian A1 - Ay, Peter ED - Zaikov, Gennadij E. ED - Pudel, Frank ED - Spychalski, Grzegorz T1 - Agricultural residues as a renewable source of bioenergy with special focus on cereal straws T2 - Renewable resources and biotechnology for material applications Y1 - 2011 SN - 978-1-61209-521-9 SP - 67 EP - 79 PB - Nova Publishers CY - Magdeburg ER - TY - CHAP A1 - Narra, Satyanarayana A1 - Geldt, Elena A1 - Glaser, Claudia A1 - Ay, Peter T1 - Technical realization of the innovative roll-agglomeration of bast fibres in industrial scale T2 - XXVII International Mineral Processing Congress, 20 - 24 October 2014, Chile, Santiago de Chile Y1 - 2014 SP - 345 EP - 355 ER - TY - CHAP A1 - Narra, Satyanarayana A1 - Logsch, Florian A1 - Glaser, Claudia A1 - Ay, Peter T1 - Sludge-pelleting of paper and pulp residues T2 - XXVI International Mineral Processing Congress - IMPC 2012, New Delhi, India, September 24 - 28, 2012 Y1 - 2012 SN - 81-901714-3-7 SP - 03723 EP - 03739 CY - New Dehli ER - TY - PAT A1 - Ay, Peter A1 - Glaser, Claudia A1 - Hildebrandt, Sven A1 - Müller-Fehn, Siegfried T1 - Verfahren und Vorrichtung zur Herstellung von kugelförmigen Fasermengen N2 - Hauptanspruch: Verfahren zur Herstellung von kugelförmigen Gebilden aus Fasern, - indem das Fasermaterial portioniert wird, - die portionierte Menge von Fasern in einem horizontal und vertikal begrenzten kreisförmig ausgebildeten Rollraum auf einem konstanten Umlaufradius einem Rollprozess unterzogen wird, der durch unterschiedliche Relativbewegungen zueinander erzeugende Rotationen einzelner ebener kreisförmiger Bauteile charakterisiert ist und - nach Erreichen einer im Wesentlichen allseitig nahezu runden Form der portionierten Menge von Fasern diese als Rollagglomerat aus dem Rollprozess ausgetragen wird. KW - Naturfasern, Rollagglomeration, Rollagglomerationsverfahren Y1 - 2006 ER - TY - PAT A1 - Ay, Peter A1 - Narra, Satyanarayana A1 - Glaser, Claudia T1 - Vorrichtung zur Herstellung von Agglomeraten N2 - Die Erfindung betrifft eine Rollagglomerations-Vorrichtung zur Herstellung von Agglomeraten aus einem Feststoff-Füssigkeitsgemisch. Die Vorrichtung weist ein Transportmittel zum Transport eines Feststoff-Flüssigkeitsgemisches in Richtung der Längsachse des Transportmittles und ein Pressmittel auf, welches so zum Transportmittel beabstandet angeordnet ist, dass ein Pressmittel auf das auf der Auflagefläche des Transportmittels befindlichen Feststoff-Flüssigkeitsgemisches einen Druck ausüben kann, wobei das Transportmittle oder das Pressmittel quer zur Längsachse des Transportmittels bewegbar sind. KW - Feststoff-Flüssigkeitsgemisch, Rollagglomerations-Vorrichtung, Rollagglomeration, Entwässerung, Agglomeratbildung, Y1 - 2014 ER - TY - PAT A1 - Narra, Satyanarayana A1 - Glaser, Claudia A1 - Ay, Peter T1 - Verfahren zur Herstellung von Langzeitdünger aus Gärresten mittels Verkapselung N2 - Die Erfindung betrifft ein Verfahren zur Herstellung von Dünger aus Gärresten, wobei die Inhaltsstoffe aus den enthaltenen Zubereitungen lang anhaltend freigesetzt werden. KW - Gärreste, Langzeitdünger, Verkapselung, Agglomerate, Aufbauagglomeration Y1 - 2014 ER - TY - PAT A1 - Narra, Satyanarayana A1 - Glaser, Claudia A1 - Ay, Peter A1 - Logsch, Florian T1 - Verfahren zur Herstellung von wasserunlöslichen Lignin-Agglomeraten N2 - Die Erfindung betrifft ein Verfahren zur Herstellung von wasserunlöslichen Agglomeraten aus Ablauge eines Cellulosegewinnungsprozesses. Erfindungsgemäß umfasst das Verfahren die folgenden Schritte: 1. Durchführung einer Granulation mit der Ablauge zur Erzeugung von Lignin-Agglomeraten und 2. Behandeln der erzeugten Lignin-Agglomerate mit einer Säure. KW - Sprühgranulation Lignin-Agglomerate, Agglomeration von Ligninen Y1 - 2013 ER - TY - GEN A1 - Ay, Peter A1 - Glaser, Claudia T1 - Aufbereitung von Fettsäuregemischen aus nachwachsenden Rohstoffen T2 - Forum der Forschung KW - Schmelzkristallisation Y1 - 2003 SN - 0947-6989 VL - 7 IS - 16 SP - 135 EP - 142 ER - TY - CHAP A1 - Hildebrandt, Sven A1 - Ay, Peter A1 - Gusovius, Hans-Jörg A1 - Glaser, Claudia A1 - Stollberg, Christian T1 - Possibilities and working of the specific agglomeration of fibrous materials and residues T2 - XXV International Mineral Processing Congress, IMPC 2010, Brisbane, Australia 6-10 September 2010 KW - Agglomeration fibrous material Y1 - 2010 PB - AusIMM CY - Carlton South, Australia ER - TY - CHAP A1 - Narra, Satyanarayana A1 - Glaser, Claudia A1 - Brinker, Mona A1 - Bednarek, R. A1 - Gusovius, Hans-Jörg A1 - Ay, Peter T1 - Vergleich verschiedener Bildanalysesysteme zur Bestimmung der Partikelgrößenverteilung von zerkleinertem Stroh und deren charakteristischer Einfluss auf Stabilität und Festigkeit von Biomassepellets T2 - Aufbereitung und Recycling, 10. und 11. November 2010, Freiberg, Jahrestagung der UVR e.V. und FIA e.v. KW - Partikelgrößenverteilungen von Stroh Y1 - 2010 SP - S. 35 CY - Freiberg ER - TY - PAT A1 - Ay, Peter A1 - Narra, Satyanarayana A1 - Glaser, Claudia T1 - System zur Rollagglomeration mit integrierter Entwässerung KW - Rollagglomeration Y1 - 2013 ER - TY - CHAP A1 - Narra, Satyanarayana A1 - Glaser, Claudia A1 - Gusovius, Hans-Jörg A1 - Stollberg, Christian A1 - Ay, Peter ED - Zaikov, Gennadij E. T1 - Agricultural residues as a renewable source of bio-Energy with special focus on cereal straws T2 - Renewable resources and biotechnology for material applications, proceeding of the 16th International Conference for Renewable Resources and Plant Biotechnology (NAROSSA 2010), held in Magdeburg, Germany, June 7 - 8, 2010 KW - Agriculture residues Y1 - 2010 SN - 978-1-61209-521-9 SP - 67 EP - 80 PB - Nova Science Publ. CY - New York ER - TY - CHAP A1 - Ay, Peter A1 - Glaser, Claudia A1 - Logsch, Florian A1 - Narra, Satyanarayana A1 - Gemende, Bernhard A1 - Gerbeth, Anja A1 - Riedel, Tobias A1 - Pausch, Nicole A1 - Leiker, Matthias A1 - Bäde, Bianka A1 - Heiduschke, Rene T1 - Micro-structured Iron (III) hydroxide agglomerates with high porosity as adsorbents T2 - Proceedings of the XXVIII International Mineral Processing Congress (IMPC 2016), September 11-15, 2016, Québec City, Canadian Institute of Mining, Metallurgy and Petroleum N2 - This study focusses on the production of micro-structured agglomerates with high porosity from iron (III)-hydroxide-containing materials as adsorbent. A fractal structure of the agglomerates was created through a two-stage agglomeration process. Developing porous structures was necessary to increase the adsorption capacity. Various materials were used for the agglomeration experiments: i) filter cake (dry matter content 23 to 27 wt.-%); ii) FerroSorp®DGμ, a product which is already being used commercially for various applications in water cleaning. These materials in the pristine state have different characteristics such as dry matter content and particle size distribution. The desired optimised agglomerates can be achieved with the help of additives or binders, respectively. Additionally, the agglomeration process parameters play a vital role. In order to produce agglomerates with high porosity, the process was carried out in two steps. Firstly, FerroSorp®DGμ (d90 < 30 µm) was agglomerated jointly with the aforementioned filter cake in an Eirich intensive mixer (particle size range 125 µm < d90 < 500 µm). The second agglomeration step post drying was carried out in a pelletisation disc or in an Eirich intensive mixer with the addition of polymeric binders (up to particle sizes ranging from 2 to 4 mm). Agglomerates were characterised both in short and long term loading tests using phosphate as model ion. Contact times were less than 10 min, similar to practical application in percolation columns, or more than 7 days, respectively. The results show that the agglomerates produced in the two-stage pelletisation process have more advantageous properties like better accessibility of the active sites obtained by specificly influencing the particle size distribution during the two-stage pelletisation process. KW - Microstructured agglomerate KW - Iron(III)-hydoxide-containing material KW - adsorption capacity Y1 - 2016 SN - 978-1-926872-29-2 ER - TY - GEN A1 - Spix, Claudia A1 - Spallek, Jacob A1 - Kaatsch, Peter A1 - Razum, Oliver A1 - Zeeb, Hajo T1 - Cancer survival among children of Turkish descent in Germany 1980-2005: a registry-based analysis T2 - BMC Cancer Y1 - 2008 U6 - https://doi.org/10.1186/1471-2407-8-355 SN - 1471-2407 VL - 8 SP - 355 ER - TY - GEN A1 - Spallek, Jacob A1 - Spix, Claudia A1 - Zeeb, Hajo A1 - Kaatsch, Peter A1 - Razum, Oliver T1 - Cancer patterns among children of Turkish descent in Germany: a study at the German Childhood Cancer Registry T2 - BMC Public Health Y1 - 2008 U6 - https://doi.org/10.1186/1471-2458-8-152 SN - 1471-2458 VL - 8 SP - 152 ER - TY - GEN A1 - Spallek, Jacob A1 - Kaatsch, Peter A1 - Spix, Claudia A1 - Ulusoy, Nazan A1 - Zeeb, Hajo A1 - Razum, Oliver T1 - Namensbasierte Identifizierung von Fällen mit türkischer Herkunft im Kinderkrebsregister Mainz T2 - Gesundheitswesen Y1 - 2006 U6 - https://doi.org/10.1055/s-2006-927166 SN - 1439-4421 SN - 0941-3790 VL - 68 IS - 10 SP - 643 EP - 649 ER - TY - GEN A1 - Löffler, Antje A1 - Luck, Tobias A1 - Then, Francisca S. A1 - Luck-Sikorski, Claudia A1 - Pabst, Alexander A1 - Kovacs, Peter A1 - Böttcher, Yvonne A1 - Breitfeld, Jana A1 - Tönjes, Anke A1 - Horstmann, Annette A1 - Löffler, Markus A1 - Engel, Christoph A1 - Thiery, Joachim A1 - Villringer, Arno A1 - Stumvoll, Michael A1 - Riedel-Heller, Steffi G. T1 - Effects of psychological eating behaviour domains on the association between socio-economic status and BMI T2 - Public Health Nutrition Y1 - 2017 U6 - https://doi.org/10.1017/S1368980017001653 SN - 1475-2727 VL - 20 IS - 15 SP - 2706 EP - 2712 ER - TY - CHAP A1 - Dasgupta, Sunanda A1 - Glaser, Claudia A1 - Ay, Peter T1 - SLE diagram for a high oleic palm oil based fatty acid mixture at low saturated content T2 - 9th Workshop on Fats and Oils as Renewable Feedstock for the Chemical Industry, March 19-21, 2017, Karlsruhe, Germany N2 - Vegetable oils and their derivatives are increasingly replacing mineral oils in their applications.[1,2] Among other constituents in vegetable oil, both saturated and unsaturated fractions are important raw materials. The latter possesses double bonds which can provide as substrates or raw materials for various chemical industries.[3] Fractionation of these oils or as in our case the Poly-Unsaturated Fatty Acid (PUFA) mixture is required so as to generate favorable compositions according to applications. Generation of Solid Liquid Equilibrium (SLE) phase diagrams for real mixtures is extremely important to enable a thorough understanding of the thermodynamics of the fractionation process of crystallization. The PUFA mixture was fractionated in a multistage scrubbing layer crystallizer. The product was put into a decanter centrifuge so as to fractionate them into mother liqor and crystal fraction. The temperature in the jacket was maintained such that △T< 5K from the liquidus point obtained from the Differential Scanning Calorimeter (DSC) thermal analyses. Each crystallizer was also maintained at a temperature 5K below the previous one. This way a slow and successive cooling of the PUFA was achieved such that probes from different fraction could be obtained. They were analyzed thermally and chemically in the DSC and Gas Chromatography – Flame Ionization Detector (GC-FID) setup respectively.[4] Similar to previous literature as in [5], technically relevant partial SLE diagrams for high oleic palm oil was created by fractionating the mixture in a scrubbed layer crystallizer along with their metastable range were determined.[6] Y1 - 2017 PB - Abiosus e.V. CY - Oldenburg ER - TY - GEN A1 - Rödiger, Stefan A1 - Liebsch, Claudia A1 - Schmidt, Carsten A1 - Lehmann, Werner A1 - Resch-Genger, U. A1 - Schedler, Uwe A1 - Schierack, Peter T1 - Nucleic acid detection based on the use of microbeads: a review T2 - Microchimica Acta Y1 - 2014 U6 - https://doi.org/10.1007/s00604-014-1243-4 SN - 0026-3672 SN - 1436-5073 VL - 181 IS - 11-12 SP - 1151 EP - 1168 ER - TY - GEN A1 - Roggenbuck, Dirk A1 - Borghi, Maria Orietta A1 - Somma, Valentina A1 - Büttner, Thomas A1 - Schierack, Peter A1 - Hanack, Katja A1 - Grossi, Claudia A1 - Bodio, Caterina A1 - Macor, Paolo A1 - Landenberg, Philipp von A1 - Boccellato, Francesco A1 - Mahler, Michael A1 - Meroni, Pier Luigi T1 - Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers T2 - Arthritis Research & Therapy Y1 - 2016 U6 - https://doi.org/10.1186/s13075-016-1018-x SN - 1465-9913 SN - 1478-6362 VL - 18 IS - 111 ER - TY - GEN A1 - Kramer, Toni A1 - Schiebel, Juliane A1 - Zelck, Claudia A1 - Weinreich, Jörg A1 - Schierack, Peter A1 - Rödiger, Stefan T1 - Genotyping and gene expression analysis of putative reference genes in Enterobacteriaceae, 67th Annual Meeting of the German Society of Hygiene and Microbiology (DGHM), 27.-30.09.2015, Münster Y1 - 2015 UR - https://f1000research.com/posters/5-248 U6 - https://doi.org/10.7490/f1000research.1111354.1 ER - TY - GEN A1 - Deutschmann, Claudia A1 - Dinter, Franziska A1 - Rödiger, Stefan A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - Comparison of Lab and Point of Care (POC) technologies – case study for CHI3L1, Potsdam Days on Bioanalysis Y1 - 2017 UR - https://www.researchgate.net/publication/321419307 ER - TY - GEN A1 - Dinter, Franziska A1 - Deutschmann, Claudia A1 - Schierack, Peter A1 - Dame, Gregory A1 - Rödiger, Stefan T1 - Integration of Cardiovascular Disease Biomarkers in a Microfluidic Microbead Chip Y1 - 2017 UR - https://f1000research.com/posters/6-2136 N1 - Potsdam Days on Bioanalysis 2017 ER - TY - GEN A1 - Liebsch, Claudia A1 - Rödiger, Stefan A1 - Böhm, Alexander A1 - Nitschke, Jörg A1 - Weinreich, Jörg A1 - Fruth, Angelika A1 - Roggenbuck, Dirk A1 - Lehmann, Werner A1 - Schedler, Uwe A1 - Juretzek, Thomas A1 - Schierack, Peter T1 - Solid-phase microbead array for multiplex O-serotyping of Escherichia coli T2 - Microchimica Acta Y1 - 2017 U6 - https://doi.org/10.1007/s00604-017-2088-4 SN - 0026-3672 SN - 1436-5073 VL - 184 IS - 5 SP - 1405 EP - 1415 ER - TY - GEN A1 - Deutschmann, Claudia A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - The loss of tolerance to CHI3L1-A putative role in inflammatory bowel disease? T2 - Clinical Immunology Y1 - 2018 U6 - https://doi.org/10/gftf2k SN - 1521-6616 VL - 199 SP - 12 EP - 17 ER - TY - GEN A1 - Reddig, Annika A1 - Rübe, Claudia E. A1 - Rödiger, Stefan A1 - Schierack, Peter A1 - Reinhold, Dirk A1 - Roggenbuck, Dirk T1 - DNA damage assessment and potential applications in laboratory diagnostics and precision medicine T2 - Journal of Laboratory and Precision Medicine Y1 - 2018 U6 - https://doi.org/10.21037/jlpm.2018.03.06 SN - 2519-9005 VL - 3 ER - TY - CHAP A1 - Logsch, Florian A1 - Glaser, Claudia A1 - Balz, Jessica A1 - Ay, Peter A1 - Leiker, Matthias A1 - Heiduschke, Rene T1 - Experimental studies of the pelletizing-flocculation process of ironhydroxide containing suspensions in a Taylor-Couette-Reactor T2 - Abstracts of the XXIX International Mineral Processing Congress : 17-21 september, 2018 N2 - The treatment of iron-hydroxide-containing water from ground water and surface water is achieved by a combination of the process steps of flocculation and subsequent mechanical dewatering. The aim is to create solid pellet structures by extending the structure forming flocculation process with a build-up pelletizing process which can be transferred directly into a drying unit. A Taylor-Couette-reactor (diameter of the inner cylinder – 40 mm, gap width – 5 mm) was used for these experimental studies. To produce the necessary flow profile the inner cylinder was rotated at a speed of 230 rpm. The iron hydroxide-containing suspension (dry matter content: 2 mass %) was added simultaneously with the addition of a cationic high-molecular flocculant in various flocculant dosages and residence times of 5 to 15 min. The pellets were examined for parameters such as geometric dimensions, dry substance content and dewatering behaviour. As the results show, there is a direct relationship between the residence time and the geometric dimensions of the pellets. After a residence time of 5 min, round pellets with an average diameter of 6 mm were formed. With an increase in the residence time up to 15 min, a compaction of the pellets could be observed, which resulted in an increase in the dry substance content of 8.0 to 11.2 mass % on average. After completion of the pelletizing process, the pellets were mechanically dewatered by filtration. By applying this innovative wet pelletizing of iron-hydroxide containing suspensions in a Taylor-Couette-reactor, it is possible to carry out the process of flocculation combined with the pellet formation with simultaneous pellet compaction in a single process step. The resulting pellet structures are distinguished from conventional floc structures by an improved water discharge capacity. After classification the pellets can be marked directly as easy-to-handle bulk material, suitable as feedstock in percolation columns for the purification of contaminated fluid streams KW - Flocculation, wet-pelletizing, Taylor-Couette-reactor, water purification, Iron(III)-hydroxide-containing material, pelletizing-flocculation Y1 - 2018 SN - 978-5-98191-086-9 SP - 189 PB - Ore and Metals, Publishing House, Moscow CY - Moscow ET - 1. Auflage ER - TY - GEN A1 - Deutschmann, Claudia A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - The loss of tolerance to CHI3L1-A putative role in inflammatory bowel disease? T2 - Clinical Immunology Y1 - 2019 U6 - https://doi.org/10.1016/j.clim.2018.12.005 SN - 1521-6616 SN - 1521-7035 VL - 199 SP - 12 EP - 17 ER - TY - GEN A1 - Deutschmann, Claudia A1 - Sowa, Mandy A1 - Murugaiyan, Jayaseelan A1 - Roessler, Uwe A1 - Röber, Nadja A1 - Conrad, Karsten A1 - Laass, Martin W. A1 - Bogdanos, Dimitrios Petrou A1 - Sipeki, Nora A1 - Papp, Maria A1 - Rödiger, Stefan A1 - Roggenbuck, Dirk A1 - Schierack, Peter T1 - Identification of Chitinase-3-Like Protein 1 as a Novel Neutrophil Antigenic Target in Crohn’s Disease T2 - Journal of Crohn's and Colitis N2 - Background and Aims There is an increasing incidence of inflammatory bowel disease [IBD]. Autoimmune responses are involved in the pathophysiology of IBD, but their underlying pathways and target antigens have not yet been fully elucidated. Methods Autoantigenic targets in IBD were identified after separation of whole cell proteins isolated from neutrophils using two-dimensional electrophoresis and matrix assisted laser desorption ionization – time of flight mass spectrometry-based protein identification of the spots that displayed Western blotting signals with anti-neutrophil cytoplasmic antibody-positive sera. The prevalence of IgG, IgA and secretory IgA [sIgA] to chitinase 3-like protein 1 [CHI3L1] was analysed by enzyme-linked immunosorbent assays using recombinant CHI3L1 in 110 patients with Crohn’s disease [CD], 95 with ulcerative colitis [UC], 126 with coeliac disease [CeD] and 86 healthy controls [HCs]. Results The 18-glycosylhydrolase family member CHI3L1 was identified as a neutrophil autoantigenic target. CD patients displayed significantly higher levels of IgG to CHI3L1 than patients with UC and CeD (p < 0.0001, respectively). IgA and sIgA to CHI3L1 was significantly higher in CD than in UC, CeD and HCs [p < 0.0001, respectively]. IgA and sIgA to CHI3L1 demonstrated the highest prevalence in CD [25.5%, 28/110; and 41.8%%, 46/110] compared to HCs [2.3%, 2/86; and 4.7%%, 4/86; p = 0.0015 and p < 0.0001] and are associated with a more complicated progression of CD. Conclusion CHI3L1 is a novel neutrophil autoantigenic target in CD. IgA and sIgA to CHI3L1 may serve as novel markers for CD and may facilitate the serological diagnosis of IBD. Y1 - 2019 U6 - https://doi.org/10.1093/ecco-jcc/jjz012 SN - 1876-4479 SN - 1873-9946 VL - 13 IS - 7 SP - 894 EP - 904 ER - TY - GEN A1 - Deutschmann, Claudia A1 - Roggenbuck, Dirk A1 - Schierack, Peter A1 - Rödiger, Stefan T1 - Autoantibody testing by enzyme-linked immunosorbent assay-a case in which the solid phase decides on success and failure T2 - Heliyon Y1 - 2020 U6 - https://doi.org/10.1016/j.heliyon.2020.e03270 SN - 2405-8440 VL - 6 IS - 1 ER - TY - CHAP A1 - Meyer, Thorsten A1 - Peter, Claudia A1 - Herzberg, Heidrun A1 - Tiesmeyer, Karin A1 - Herrmann, Wolfram J. A1 - Stamer, Maren ED - Ohlbrecht, Heike ED - Bartel, Susanne ED - Detka, Carsten ED - Herrmann, Wolfram J. ED - Herzberg, Heidrun ED - Meyer, Thorsten ED - Peter, Claudia ED - Seltrecht, Astrid ED - Stamer, Maren ED - Tegethoff, Dorothea ED - Tiesmeyer, Karin T1 - Methoden im Wandel? Überlegungen zur Weiterentwicklung der Methoden qualitativer Gesundheitsforschung T2 - Perspektiven qualitativer Gesundheitsforschung Y1 - 2020 SN - 978-3-7799-3687-9 SN - 978-3-7799-4689-2 SP - 272 EP - 280 PB - Beltz CY - Weinheim ER - TY - GEN A1 - Comabella, Manual A1 - Deutschmann, Claudia A1 - Midaglia, Luciana A1 - Schierack, Peter A1 - Martínez, Júlia A1 - Roggenbuck, Dirk A1 - Montalban, Xavier T1 - Chitinase 3-like 1 is not a target antigen in patients with multiple sclerosis T2 - Multiple Sclerosis Journal Y1 - 2021 U6 - https://doi.org/10.1177/1352458520980141 SN - 1477-0970 SN - 1352-4585 VL - 27 IS - 9 SP - 1455 EP - 1457 ER - TY - GEN A1 - Buchanan, Erin M. A1 - Lewis, Savannah C. A1 - Paris, Bastien A1 - Forscher, Patrick S. A1 - Pavlacic, Jeffrey M. A1 - Beshears, Julie E. A1 - Drexler, Shira Meir A1 - Gourdon-Kanhukamwe, Amélie A1 - Mallik, Peter R A1 - Silan, Miguel Alejandro A. A1 - Miller, Jeremy K. 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A1 - Noone, Chris A1 - Onie, Sandersan A1 - Verbruggen, Frederick A1 - Radtke, Theda A1 - Primbs, Maximilian A. T1 - The psychological science accelerator’s COVID-19 rapid-response dataset T2 - Scientific Data Y1 - 2023 U6 - https://doi.org/10.1038/s41597-022-01811-7 SN - 2052-4463 VL - 10 IS - 1 SP - 1 EP - 15 PB - Springer Science and Business Media LLC ER -