TY - GEN A1 - Shishkov, Alexander V. A1 - Bogacheva, Elena Nikolaevna A1 - Dolgov, Alexey A. A1 - Chulikov, Alexey L. A1 - Knyazev, Denis G. A1 - Fedorova, Natalia V. A1 - Ksenofontov, Alexander L. A1 - Kordyukova, Larisa V. A1 - Lukashina, Elena V. A1 - Mirsky, Vladimir M. A1 - Baratova, Lyudmila A. T1 - The in situ structural characterization of the influenza A virus matrix M1 protein within a virion T2 - Protein and Peptide Letters N2 - The first attempt has been made to suggest a model of influenza A virus matrix M1 protein spatial structure and molecule orientation within a virion on the basis of tritium planigraphy data and theoretical prediction results. Limited in situ proteolysis of the intact virions with bromelain and surface plasmon resonance spectroscopy study of the M1 protein interaction with lipid coated surfaces were used for independent confirmation of the proposed model. KW - Influenza A virus KW - matrix M1 protein KW - secondary structure prediction KW - tritium planigraphy KW - surface plasmon resonance spectroscopy KW - three-dimensional modeling Y1 - 2009 U6 - https://doi.org/10.2174/092986609789353682 SN - 0929-8665 SN - 1875-5305 VL - 16 IS - 11 SP - 1407 EP - 1413 ER -