<?xml version="1.0" encoding="utf-8"?>
<export-example>
  <doc>
    <id>34983</id>
    <completedYear/>
    <publishedYear>2024</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>263</pageFirst>
    <pageLast>273</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>86 (2024)</volume>
    <type>articler</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2025-01-06</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Novel high-resolution contrast agent  ultrasound techniques HiFR CEUS and SR  CEUSin combination with shear wave  elastography, fat assessment and viscosity  of liver parenchymal changes and tumors</title>
    <abstract language="eng">Abstract.&#13;
 BACKGROUND: The continuous development of ultrasound techniques increasingly enables better description and visu&#13;
alization of unclear lesions. New ultrasound systems must be evaluated with regard to all these diagnostic possibilities.&#13;
 METHODS:Amultifrequency C1-7 convex probe (SC7-1M) with the new high-end system Resona A20 Series was used  moderntechnologies, includingHiFRCEUS, SRCEUSandmultimodaltissueimaging withs hearwaveelastography(SWE),  fat evaluation and viscosity measurements (M-Ref) were applied.&#13;
 RESULTS:Ofn=70(meanvalue 48,3 years±20,3 years, range 18–84 years) cases examined, a definitive diagnosis could  be made in n=67 cases, confirmed by reference imaging and/or follow-up. Of these, n=22 cases were malignant changes  (HCC (hepatocellular carcinoma) n=9, CCC (cholangiocellular carcinoma) n=3, metastases of colorectal carcinomas or&#13;
 recurrences of HCC n=10). In all 12 cases of HCC or CCC, the elastography measurements using the shear wave technique  (with values &gt;2m/s to 3.7m/s) showed mean values of 2.3±0.31m/s and a degree of fibrosis of F2 to F4. In n=14 cases,  changes in the fat measurement (range 0.51 to 0.72dB/cm/MHz, mean values 0.58±0.12dB/cm/MHz) in the sense of  proportional fatty changes in the liver were detected. In the 4 cases of localized fat distribution disorders, the values were  &gt;0.7dB/cm/MHz in the sense of significant fatty deposits in the remaining liver tissue. Relevant changes in the viscosity measurements with values &gt;1.8kPa were found in n=31 cases, in n=5 cases of cystic lesions with partially sclerosing  cholangitis, in n=13 cases of malignant lesions and in n=9 cases post-interventionally, but also in n=4 cases of benign foci  with additional systemic inflammation.&#13;
 CONCLUSIONS:The results are promising and show a new quality of ultrasound-based liver diagnostics. However, there  is a need for further investigations with regard to the individual aspects, preferably on a multi-center basis.</abstract>
    <parentTitle language="eng">Clinical Hemorheology and Microcirculation</parentTitle>
    <identifier type="url">https://content.iospress.com/download/clinical-hemorheology-and-microcirculation/ch249103?id=clinical-hemorheology-and-microcirculation%2Fch249103</identifier>
    <identifier type="doi">10.3233/CH-249103</identifier>
    <enrichment key="Fprofil">2 Gesundheit und Lifes Sciences / Health and Life Sciences</enrichment>
    <enrichment key="BTU">an der BTU erstellt / created at BTU</enrichment>
    <enrichment key="Publikationsweg">Open Access</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">false</enrichment>
    <author>
      <firstName>E.M.</firstName>
      <lastName>Jung</lastName>
    </author>
    <submitter>
      <firstName>Christian</firstName>
      <lastName>Schulz</lastName>
    </submitter>
    <author>
      <firstName>U.</firstName>
      <lastName>Kaiser</lastName>
    </author>
    <author>
      <firstName>W.</firstName>
      <lastName>Herr</lastName>
    </author>
    <author>
      <firstName>C.</firstName>
      <lastName>Stroszczynski</lastName>
    </author>
    <author>
      <firstName>F.</firstName>
      <lastName>Jung</lastName>
    </author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Multimodal liver tissue imaging (M-Ref)</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>UMA</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>HiFR CEUS</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>SR CEUS</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Elastography</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Fat evaluation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Viscosity</value>
    </subject>
    <collection role="institutes" number="2110">FG Molekulare Zellbiologie</collection>
  </doc>
  <doc>
    <id>34992</id>
    <completedYear/>
    <publishedYear>2024</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>362</pageFirst>
    <pageLast>371</pageLast>
    <pageNumber/>
    <edition/>
    <issue>3</issue>
    <volume>33</volume>
    <type>articler</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2025-01-06</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Dynamic Contrast Ultrasound Diagnostics (CEUS) of Liver Lesions and Post-treatment Control with A New High-resolution Examination Technique (HiFR) and Perfusion</title>
    <abstract language="eng">Background &amp;amp; Aims: To evaluate, if high frame rate (HiFR) contrast-enhanced ultrasound (CEUS) and external perfusion analysis (VueBox®)can give answers on liver tumour diagnostics. Methods: A multifrequency probe (C1-6 /Resona R9) and 1-2.4 ml ultrasound contrast medium were used for CEUS up to 5-6 min. Independent analysis of DICOM-CINE files was performed, correlated to follow-up, computed tomography, magnetic resonance imaging, or histopathology. Results: In 110 patients the difference between marginal peak enhancement (PE) of malignant and benign leasions was significant. In the peripheral area, the AUCs were lower in malignant lesions (144.8±139.3) than in benign lesions (123.6±119.8). The mean transit time (mTT) was shorter in malignant lesions in the center. In the liver parenchyma, however, the mTT was significantly longer in malignant lesions (141.6±107.9s) than in benign lesions (128.8±138.6 s). The rise time (RT) was significantly shorter central (66.5±30.9s) and peripheral (72.8±35.1s) in malignant lesions than in benign lesions (114.33±159.58s). The wash in rate (WiR) in benign lesions was 848.3±2,563.7 rU in the center. Wash-out rate (WoR) in the center, peripheral and in the liver parenchyma showed a significantly lower wash-out in the malignant lesions. Conclusions: HiFR CEUS with perfusion analysis enables the assessment of focal, diffuse and postinterventional liver changes.</abstract>
    <parentTitle language="eng">Journal of Gastrointestinal &amp; Liver Diseases</parentTitle>
    <identifier type="doi">10.15403/jgld-5589</identifier>
    <enrichment key="Fprofil">2 Gesundheit und Lifes Sciences / Health and Life Sciences</enrichment>
    <enrichment key="BTU">an der BTU erstellt / created at BTU</enrichment>
    <enrichment key="Publikationsweg">Open Access</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">false</enrichment>
    <author>
      <firstName>EM</firstName>
      <lastName>Jung</lastName>
    </author>
    <submitter>
      <firstName>Christian</firstName>
      <lastName>Schulz</lastName>
    </submitter>
    <author>
      <firstName>L</firstName>
      <lastName>Pleyer</lastName>
    </author>
    <author>
      <firstName>I</firstName>
      <lastName>Dropco</lastName>
    </author>
    <author>
      <firstName>U</firstName>
      <lastName>Kaiser</lastName>
    </author>
    <author>
      <firstName>D</firstName>
      <lastName>Yi</lastName>
    </author>
    <author>
      <firstName>C</firstName>
      <lastName>Stroszczynski</lastName>
    </author>
    <author>
      <firstName>F</firstName>
      <lastName>Jung</lastName>
    </author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Ultrasound contrast media</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Magnetic resonance imaging</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Contrast-enhanced ultrasound</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Liver analysis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Perfusion</value>
    </subject>
    <collection role="institutes" number="2110">FG Molekulare Zellbiologie</collection>
  </doc>
</export-example>
