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<export-example>
  <doc>
    <id>22724</id>
    <completedYear/>
    <publishedYear>2018</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>15</pageFirst>
    <pageLast>17</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>114</volume>
    <type>articler</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2018-11-21</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">An experimental litmus test of the emerging hypothesis that persistent physical symptoms can be explained as perceptual dysregulation</title>
    <parentTitle language="eng">Journal of Psychosomatic Research</parentTitle>
    <identifier type="doi">10.1016/j.jpsychores.2018.08.007</identifier>
    <identifier type="issn">1879-1360</identifier>
    <identifier type="issn">0022-3999</identifier>
    <enrichment key="BTU">an der BTU erstellt / created at BTU</enrichment>
    <author>
      <firstName>Nadine</firstName>
      <lastName>Lehnen</lastName>
    </author>
    <submitter>
      <firstName>Stefan</firstName>
      <lastName>Glasauer</lastName>
    </submitter>
    <author>
      <firstName>Cecilia</firstName>
      <lastName>Ramaioli</lastName>
    </author>
    <author>
      <firstName>Peter</firstName>
      <lastName>Henningsen</lastName>
    </author>
    <author>
      <firstName>Stefan</firstName>
      <lastName>Glasauer</lastName>
    </author>
    <collection role="institutes" number="1403">FG Computational Neuroscience</collection>
  </doc>
  <doc>
    <id>24659</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>385</pageFirst>
    <pageLast>400</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>249</volume>
    <type>articler</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation>BTU Cottbus-Senftenberg</contributingCorporation>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2019-11-14</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Deficient head motor control in functional dizziness: Experimental evidence of central sensory-motor dysfunction in persistent physical symptoms</title>
    <abstract language="eng">Understanding the mechanisms of symptoms that are insufficiently explained by organic dysfunction remains challenging. Recently, it has been proposed that such “functional symptoms” are based on erroneous sensory processing in the central nervous system (CNS), with internal expectations dominating sensory inputs.&#13;
&#13;
In a pilot study, we used a head motor control set-up to assess the interplay between sensory input and expectation on the example of patients with functional dizziness. Eight patients and 11 age-matched healthy controls performed large active eye-head gaze shifts towards visual targets in the natural situation and with the head moment of inertia 3.3-fold increased. The latter induces head oscillations and the expected sensory outcome of the movement, estimated in the CNS, does not match the actual sensory input. Head oscillations were assessed in patients and in healthy subjects and compared to prior results from patients with organic disease (vestibular loss and cerebellar ataxia). Head oscillations in patients with functional dizziness were different from those of healthy subjects (F(1,17) = 27.26, P &lt; 0.001, partial η2 = 0.62), and similar to those of patients with cerebellar ataxia, and with vestibular loss (F(2,19) = 0.56, P = 0.58). Even in the natural, unweighted, condition, head oscillations were higher in functional dizziness patients than in healthy subjects (P = 0.001). Since an extensive work-up failed to demonstrate any explanatory peripheral vestibular, motor, or cerebellar organic dysfunction, these motor control deficits are a first indication of erroneous interplay between expectations and sensory input in the CNS that could account for persistent physical symptoms.</abstract>
    <parentTitle language="eng">Progress in Brain Research</parentTitle>
    <identifier type="doi">10.1016/bs.pbr.2019.02.006</identifier>
    <identifier type="issn">1875-7855</identifier>
    <identifier type="issn">0079-6123</identifier>
    <enrichment key="BTU">an der BTU erstellt / created at BTU</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">false</enrichment>
    <author>
      <firstName>Nadine</firstName>
      <lastName>Lehnen</lastName>
    </author>
    <submitter>
      <firstName>Stefan</firstName>
      <lastName>Glasauer</lastName>
    </submitter>
    <author>
      <firstName>Lena</firstName>
      <lastName>Schröder</lastName>
    </author>
    <author>
      <firstName>Peter</firstName>
      <lastName>Henningsen</lastName>
    </author>
    <author>
      <firstName>Stefan</firstName>
      <lastName>Glasauer</lastName>
    </author>
    <author>
      <firstName>Cecilia</firstName>
      <lastName>Ramaioli</lastName>
    </author>
    <collection role="institutes" number="1403">FG Computational Neuroscience</collection>
  </doc>
  <doc>
    <id>25700</id>
    <completedYear/>
    <publishedYear>2020</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>527</pageFirst>
    <pageLast>528</pageLast>
    <pageNumber/>
    <edition/>
    <issue>5</issue>
    <volume>82</volume>
    <type>articler</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-05-19</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Complementing conceptual models of persistent somatic symptoms with mathematical formalization</title>
    <parentTitle language="eng">Psychosomatic Medicine</parentTitle>
    <identifier type="doi">10.1097/PSY.0000000000000801</identifier>
    <identifier type="issn">1534-7796</identifier>
    <enrichment key="BTU">an der BTU erstellt / created at BTU</enrichment>
    <enrichment key="Fprofil">2 Gesundheit und Lifes Sciences / Health and Life Sciences</enrichment>
    <enrichment key="Fprofil">4 Künstliche Intelligenz und Sensorik / Artificial Intelligence and Sensor Technology</enrichment>
    <author>
      <firstName>Nadine</firstName>
      <lastName>Lehnen</lastName>
    </author>
    <submitter>
      <firstName>Stefan</firstName>
      <lastName>Glasauer</lastName>
    </submitter>
    <author>
      <firstName>Katharina</firstName>
      <lastName>Radziej</lastName>
    </author>
    <author>
      <firstName>Angelika</firstName>
      <lastName>Weigel</lastName>
    </author>
    <author>
      <firstName>Roland von</firstName>
      <lastName>Känel</lastName>
    </author>
    <author>
      <firstName>Stefan</firstName>
      <lastName>Glasauer</lastName>
    </author>
    <author>
      <firstName>Victor</firstName>
      <lastName>Pietron</lastName>
    </author>
    <author>
      <firstName>Omer</firstName>
      <lastName>Van den Bergh</lastName>
    </author>
    <author>
      <firstName>Bernd</firstName>
      <lastName>Löwe</lastName>
    </author>
    <author>
      <firstName>Marco</firstName>
      <lastName>Lehmann</lastName>
    </author>
    <author>
      <firstName>Peter</firstName>
      <lastName>Henningsen</lastName>
    </author>
    <collection role="institutes" number="1403">FG Computational Neuroscience</collection>
  </doc>
  <doc>
    <id>27927</id>
    <completedYear/>
    <publishedYear>2021</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>15</volume>
    <type>articler</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-11-15</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Unstable Gaze in Functional Dizziness: A Contribution to Understanding the Pathophysiology of Functional Disorders</title>
    <abstract language="eng">Objective: We are still lacking a pathophysiological mechanism for functional disorders explaining the emergence and manifestation of characteristic, severely impairing bodily symptoms like chest pain or dizziness. A recent hypothesis based on the predictive coding theory of brain function suggests that in functional disorders, internal expectations do not match the actual sensory body states, leading to perceptual dysregulation and symptom perception. To test this hypothesis, we investigated the account of internal expectations and sensory input on gaze stabilization, a physiologically relevant parameter of gaze shifts, in functional dizziness.&#13;
Methods: We assessed gaze stabilization in eight functional dizziness patients and 11 healthy controls during two distinct epochs of large gaze shifts: during a counter- rotation epoch (CR epoch), where the brain can use internal models, motor planning, and resulting internal expectations to achieve internally driven gaze stabilization; and during an oscillation epoch (OSC epoch), where, due to terminated motor planning, no movement expectations are present, and gaze is stabilized by sensory input alone.&#13;
Results: Gaze stabilization differed between functional patients and healthy controls only when internal movement expectations were involved [F(1,17) = 14.63, p = 0.001, and partial η2 = 0.463]: functional dizziness patients showed reduced gaze stabilization during the CR (p = 0.036) but not OSC epoch (p = 0.26).&#13;
Conclusion: While sensory-driven gaze stabilization is intact, there are marked, well- measurable deficits in internally-driven gaze stabilization in functional dizziness pointing at internal expectations that do not match actual body states. This experimental evidence supports the perceptual dysregulation hypothesis of functional disorders and is an important step toward understanding the underlying pathophysiology.</abstract>
    <parentTitle language="eng">Frontiers in Neuroscience</parentTitle>
    <identifier type="doi">10.3389/fnins.2021.685590</identifier>
    <identifier type="issn">1662-453X</identifier>
    <identifier type="issn">1662-4548</identifier>
    <enrichment key="BTU">an der BTU erstellt / created at BTU</enrichment>
    <enrichment key="Artikelnummer">685590</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">false</enrichment>
    <enrichment key="Fprofil">2 Gesundheit und Lifes Sciences / Health and Life Sciences</enrichment>
    <enrichment key="Fprofil">4 Künstliche Intelligenz und Sensorik / Artificial Intelligence and Sensor Technology</enrichment>
    <author>
      <firstName>Lena</firstName>
      <lastName>Schröder</lastName>
    </author>
    <submitter>
      <firstName>Stefan</firstName>
      <lastName>Glasauer</lastName>
    </submitter>
    <author>
      <firstName>Dina von</firstName>
      <lastName>Werder</lastName>
    </author>
    <author>
      <firstName>Cecilia</firstName>
      <lastName>Ramaioli</lastName>
    </author>
    <author>
      <firstName>Thomas</firstName>
      <lastName>Wachtler</lastName>
    </author>
    <author>
      <firstName>Peter</firstName>
      <lastName>Henningsen</lastName>
    </author>
    <author>
      <firstName>Stefan</firstName>
      <lastName>Glasauer</lastName>
    </author>
    <author>
      <firstName>Nadine</firstName>
      <lastName>Lehnen</lastName>
    </author>
    <collection role="institutes" number="1403">FG Computational Neuroscience</collection>
  </doc>
</export-example>
