<?xml version="1.0" encoding="utf-8"?>
<export-example>
  <doc>
    <id>31079</id>
    <completedYear/>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1523</pageFirst>
    <pageLast>1531</pageLast>
    <pageNumber/>
    <edition/>
    <issue>6</issue>
    <volume>241</volume>
    <type>articler</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2023-06-20</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Assessment of vestibulo-ocular reflex and its adaptation during stop-and-go car rides in motion sickness susceptible passengers</title>
    <abstract language="eng">Motion sickness is a physiological condition that negatively impacts a person's comfort and will be an emerging condition in autonomous vehicles without proper countermeasures. The vestibular system plays a key role in the origin of motion sickness. Understanding the susceptibility and (mal) adaptive mechanisms of the highly integrated vestibular system is a prerequisite for the development of countermeasures. We hypothesize a differential association between motion sickness and vestibular function in healthy individuals with and without susceptibility for motion sickness. We quantified vestibular function by measuring the high-frequency vestibulo-ocular reflex (VOR) using video head impulse testing (vHIT) in 17 healthy volunteers before and after a 11 min motion sickness-inducing naturalistic stop-and-go car ride on a test track (Dekra Test Oval, Klettwitz, Germany). The cohort was classified as motion sickness susceptible (n = 11) and non-susceptible (n = 6). Six (out of 11) susceptible participants developed nausea symptoms, while a total of nine participants were free of these symptoms. The VOR gain (1) did not differ significantly between participant groups with (n = 8) and without motion sickness symptoms (n = 9), (2) did not differ significantly in the factor time before and after the car ride, and showed no interaction between symptom groups and time, as indicated by a repeated measures ANOVA (F(1,15) = 2.19, p = 0.16. Bayesian inference confirmed that there was “anecdotal evidence” for equality of gain rather than difference across groups and time (BF10 &lt; 0.77). Our results suggest that individual differences in VOR measures or adaptation to motion sickness provocative stimuli during naturalistic stop-and-go driving cannot predict motion sickness susceptibility or the likelihood of developing motion sickness.</abstract>
    <parentTitle language="eng">Experimental Brain Research</parentTitle>
    <identifier type="doi">10.1007/s00221-023-06619-4</identifier>
    <identifier type="issn">1432-1106</identifier>
    <identifier type="issn">0014-4819</identifier>
    <enrichment key="BTU">an der BTU erstellt / created at BTU</enrichment>
    <enrichment key="Publikationsweg">Open Access</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="Fprofil">2 Gesundheit und Lifes Sciences / Health and Life Sciences</enrichment>
    <enrichment key="Fprofil">4 Künstliche Intelligenz und Sensorik / Artificial Intelligence and Sensor Technology</enrichment>
    <submitter>
      <firstName>Anja</firstName>
      <lastName>Standfuß</lastName>
    </submitter>
    <author>
      <firstName>Cecilia</firstName>
      <lastName>Ramaioli</lastName>
    </author>
    <author>
      <firstName>Tobias</firstName>
      <lastName>Steinmetzer</lastName>
    </author>
    <author>
      <firstName>Adrian</firstName>
      <lastName>Brietzke</lastName>
    </author>
    <author>
      <firstName>Paul</firstName>
      <lastName>Meyer</lastName>
    </author>
    <author>
      <firstName>Rebecca</firstName>
      <lastName>Pham Xuan</lastName>
    </author>
    <author>
      <firstName>Erich</firstName>
      <lastName>Schneider</lastName>
    </author>
    <author>
      <firstName>Martin</firstName>
      <lastName>Gorges</lastName>
    </author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Video head impulse test</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Vestibulo-ocular reflex</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Adaptation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Motion sickness</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Stop-and-go car ride</value>
    </subject>
    <collection role="institutes" number="1400">Institut für Medizintechnologie</collection>
    <collection role="institutes" number="1402">FG Medizinische Informationssysteme</collection>
  </doc>
</export-example>
