@inproceedings{MaiDauderstaedtPahneretal., author = {Mai, Andreas and Dauderst{\"a}dt, Ulrike and Pahner, D. and Krellmann, M. and Schmeißer, Dieter and Wagner, M.}, title = {In situ determination of laser induced degradation of micro-mirror arrays}, series = {International Students and Young Scientists Workshop Photonics and Microsystems, Cottbus, Germany, 8 - 10 June 2011}, booktitle = {International Students and Young Scientists Workshop Photonics and Microsystems, Cottbus, Germany, 8 - 10 June 2011}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4577-1651-5}, doi = {10.1109/STYSW.2011.6155850}, pages = {84 -- 88}, abstract = {The Fraunhofer Institute for Photonic Microsystems (Fraunhofer IPMS) develops spatial light modulators (SLMs) based on arrays of tiltable micro mirrors on a semiconductor chip. Typical applications are pattern generation for deepUV-laser mask writing or structured illumination in microscopy. Development and optimization of such SLMs requires detailed knowledge of the device behaviour under operating conditions. Here, the flatness of each single mirror effects the image resolution and contrast of the generated pattern and is amongst others a characteristic property of SLMs. In this context a surface topography measurement under laser exposure (in situ) was designed. The interferometric setup uses the phase-shift principle and allows a resolution in z-direction in the single-digit nanometer range. During irradiation with UV-laser light at 248 nm (KrF) and energy densities of up to 20 mJ/cm2 the change in single micro-mirrors topography was detected in situ. Measurementswith varying pulse energies were carried out to identify an impacton the device performance. In general, the setup is neither limited to a specific illumination wavelength nor to micro-mirrors as structures under test.}, language = {en} } @techreport{MuellerDieterBauhusetal., author = {M{\"u}ller, J{\"o}rg and Dieter, M. and Bauhus, J. and Spellmann, H. and M{\"o}hring, B. and Wagner, S. and Wolf, Heino and Niekisch, M. and Weiger, H. and Feindt, Peter H. and Hamm, Ulrich and W{\"a}tzold, Frank and Wolters, Volkmar and Engels, Eve-Marie and Schraml, U. and Lang, F. and Pr{\"o}bstl-Haider, U. and Richter, K.}, title = {Wege zu einem effizienten Waldnaturschutz in Deutschland. Stellungnahme}, publisher = {Wissenschaftlicher Beirat Waldpolitik und Wissenschaftlicher Beirat Biodiversit{\"a}t und Genetische Ressourcen beim BMEL}, pages = {62}, language = {de} } @incollection{PickenhainWagner, author = {Pickenhain, Sabine and Wagner, M.}, title = {Optimal Control Problems with a First Order PDE System - Necessary and Sufficient Optimality Conditions}, series = {Online optimization of large scale systems}, booktitle = {Online optimization of large scale systems}, editor = {Gr{\"o}tschel, Martin}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {3-540-42459-8}, pages = {159 -- 172}, language = {en} } @incollection{HenkelSchwiertzWagneretal., author = {Henkel, Karsten and Schwiertz, Carola and Wagner, S. and Valdeig, A. and List, M. and Schmeißer, Dieter}, title = {Partikel- und Tropfendetektion im Mikrometerbereich mittels Schwingquarzen}, publisher = {w.e.b.-Univ.-Verl.}, address = {Dresden}, isbn = {3-935712-92-8}, pages = {291 -- 294}, language = {de} } @article{PickenhainWagner, author = {Pickenhain, Sabine and Wagner, M.}, title = {Pontryagin principle for state-constrained control problems governed by a first-order PDE system}, language = {en} } @article{Wagner, author = {Wagner, M.}, title = {Transportation flow problems with Radon measure variables}, language = {en} } @incollection{PickenhainWagner, author = {Pickenhain, Sabine and Wagner, M.}, title = {Critical points in relaxed deposit problems}, series = {Calculus of variations and optimal control, Technion 1998, proceedings of the International Conference on the Calculus of Variations and Related Topics, 25 - 31 March, 1998}, booktitle = {Calculus of variations and optimal control, Technion 1998, proceedings of the International Conference on the Calculus of Variations and Related Topics, 25 - 31 March, 1998}, editor = {Ioffe, Alexander}, publisher = {Chapman \& Hall/CRC}, address = {Boca Raton, Fla. [u.a.]}, isbn = {0-8493-0605-1}, pages = {217 -- 236}, language = {en} } @article{Wagner, author = {Wagner, M.}, title = {Pontryagin's maximum principle for Dieudonne-Rashevsky type problems involving Lipschitz functions}, language = {en} } @article{LykinaPickenhainWagner, author = {Lykina, Valeriya and Pickenhain, Sabine and Wagner, M.}, title = {Different interpretations of the improper integral objective in an infinite horizon control problem}, language = {en} } @article{LykinaPickenhainWagner, author = {Lykina, Valeriya and Pickenhain, Sabine and Wagner, M.}, title = {On a resource allocation model with inifinite horizon}, language = {en} } @incollection{HerreJasparsWagner, author = {Herre, Heinrich and Jaspars, Jan O. M. and Wagner, Gerd}, title = {What is Negation?}, language = {en} } @misc{SchwarzkopfDirsyteDevietal., author = {Schwarzkopf, Jutta and Dirsyte, R. and Devi, A. and Kwasniewski, A. and Schmidbauer, M. and Wagner, Gerd and Michling, Marcel and Schmeißer, Dieter and Fornari, Robert}, title = {Influence of Na on the structure of Bi4Ti3O12 films deposited by liquid-delivery spin MOCVD}, series = {Thin solid films}, volume = {519}, journal = {Thin solid films}, number = {17}, issn = {0040-6090}, pages = {5754 -- 5759}, language = {en} } @misc{GrahmannMertenOstendorfetal., author = {Grahmann, Jan and Merten, Andr{\´e} and Ostendorf, Ralf and Fontenot, M. and Bleh, Daniela and Schenk, Harald and Wagner, Hans-Joachim}, title = {Tunable external cavity quantum cascade lasers (EC-QCL): an application field for MOEMS based scanning gratings}, series = {SPIE Conference: MOEMS and Miniaturized Systems XIII, San Francisco, 2014}, journal = {SPIE Conference: MOEMS and Miniaturized Systems XIII, San Francisco, 2014}, publisher = {SPIE Press}, address = {Bellingham}, isbn = {978-0-8194-9890-8}, pages = {897708-1 -- 897708-11}, language = {en} } @inproceedings{BlehOstendorfMertenetal., author = {Bleh, D. and Ostendorf, Ralf and Merten, A. and Grahmann, Jan and Schenk, Harald and Kunzer, M. and Schmidt, R. and Wagner, J.}, title = {Miniaturization of a fast tunable external cavity QCL with customized gratings and MOEMS components}, series = {International Quantum Cascade Lasers School \& Workshop (IQCLSW), Policoro, Italy}, booktitle = {International Quantum Cascade Lasers School \& Workshop (IQCLSW), Policoro, Italy}, pages = {1 -- 2}, language = {en} } @misc{LehnenHeuserSağlametal., author = {Lehnen, Nadine and Heuser, Fabian and Sağlam, Murat and Schulz, Christian M. and Wagner, Klaus J. and Taki, Masakatsu and Kochs, Eberhard F. and Jahn, Klaus and Schneider, Erich}, title = {Opioid-induced nausea involves a vestibular problem preventable by head-rest}, series = {PLoS one}, volume = {10}, journal = {PLoS one}, number = {8}, issn = {1932-6203}, doi = {10.1371/journal.pone.0135263}, pages = {e0135263}, language = {en} } @misc{KuenzelHoffmannWeberetal., author = {K{\"u}nzel, Stephan R. and Hoffmann, Maximilian and Weber, Silvio and K{\"u}nzel, Karolina and K{\"a}mmerer, Susanne and G{\"u}nscht, Mario and Klapproth, Erik and Rausch, Johanna S. E. and Sadek, Mirna S. and Kolanowski, Tomasz and Meyer-Roxlau, Stefanie and Piorkowski, Christopher and Tugtekin, Sems M. and Rose-John, Stefan and Yin, Xiaoke and Mayr, Manuel and Kuhlmann, Jan Dominik and Wimberger, Pauline and Gr{\"u}tzmann, Konrad and Herzog, Natalie and K{\"u}pper, Jan-Heiner and O'Reilly, Molly and Kabir, S. Nashitha and Sommerfeld, Laura C. and Guan, Kaomei and Wielockx, Ben and Fabritz, Larissa and Nattel, Stanley and Ravens, Ursula and Dobrev, Dobromir and Wagner, Michael and El-Armouche, Ali}, title = {Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation}, series = {Circulation Research}, volume = {129}, journal = {Circulation Research}, number = {8}, issn = {1524-4571}, doi = {10.1161/CIRCRESAHA.121.319425}, pages = {804 -- 820}, abstract = {Rationale: Fibrosis promotes the maintenance of atrial fibrillation (AF), making it resistant to therapy. Improved understanding of the molecular mechanisms leading to atrial fibrosis will open new pathways toward effective antifibrotic therapies. Objective: This study aims to decipher the mechanistic interplay between PLK2 (polo-like kinase 2) and the profibrotic cytokine OPN (osteopontin) in the pathogenesis of atrial fibrosis and AF. Methods and Results: Atrial PLK2 mRNA expression was 10-fold higher in human fibroblasts than in cardiomyocytes. Compared with sinus rhythm, right atrial appendages and isolated right atrial fibroblasts from patients with AF showed downregulation of PLK2 mRNA and protein, along with increased PLK2 promotor methylation. Genetic deletion as well as pharmacological inhibition of PLK2 induced profibrotic phenotype conversion in cardiac fibroblasts and led to a striking de novo secretion of OPN. Accordingly, PLK2-deficient (PLK2 knockout) mice showed cardiac fibrosis and were prone to experimentally induced AF. In line with these findings, OPN plasma levels were significantly higher only in patients with AF with atrial low-voltage zones (surrogates of fibrosis) compared with sinus rhythm controls. Mechanistically, we identified ERK1/2 as the relevant downstream mediator of PLK2 leading to increased OPN expression. Finally, oral treatment with the clinically available drug mesalazine, known to inhibit ERK1/2, prevented cardiac OPN overexpression and reversed the pathological PLK2 knockout phenotype in PLK2 knockout mice. Conclusions: Abnormal PLK2/ERK1/2/OPN axis function critically contributes to AF-related atrial fibrosis, suggesting reinforcing PLK2 activity and/or OPN inhibition as innovative targets to prevent fibrosis progression in AF. Mesalazine derivatives may be used as lead compounds for the development of novel anti-AF agents targeting fibrosis.}, language = {en} } @misc{SteuerLiedkeButterlingetal., author = {Steuer, O. and Liedke, Maciej O. and Butterling, M. and Schwarz, D. and Schulze, J. and Li, Z. and Wagner, A. and Fischer, Inga Anita and H{\"u}bner, R. and Zhou, S.}, title = {Evolution of point defects in pulsed-laser-melted Ge1-xSnx probed by positron annihilation lifetime spectroscopy}, series = {Journal of Physics: Condensed Matter}, volume = {36}, journal = {Journal of Physics: Condensed Matter}, number = {8}, issn = {0953-8984}, doi = {10.1088/1361-648X/ad0a10}, pages = {1 -- 11}, abstract = {Direct-band-gap Germanium-Tin alloys (Ge1-xSnx) with high carrier mobilities are promising materials for nano- and optoelectronics. The concentration of open volume defects in the alloy, such as Sn and Ge vacancies, influences the final device performance. In this article, we present an evaluation of the point defects in molecular-beam-epitaxy grown Ge1-xSnx films treated by post-growth nanosecond-range pulsed laser melting (PLM). Doppler broadening - variable energy positron annihilation spectroscopy and variable energy positron annihilation lifetime spectroscopy are used to investigate the defect nanostructure in the Ge1-xSnx films exposed to increasing laser energy density. The experimental results, supported with ATomic SUPerposition calculations, evidence that after PLM, the average size of the open volume defects increases, which represents a raise in concentration of vacancy agglomerations, but the overall defect density is reduced as a function of the PLM fluence. At the same time, the positron annihilation spectroscopy analysis provides information about dislocations and Ge vacancies decorated by Sn atoms. Moreover, it is shown that the PLM reduces the strain in the layer, while dislocations are responsible for trapping of Sn and formation of small Sn-rich-clusters.}, language = {en} } @misc{DropcoKaiserWagneretal., author = {Dropco, Ivor and Kaiser, Ulrich and Wagner, Lola and Brunner, Stefan M. and Schlitt, Hans J{\"u}rgen and Stroszczynski, Christian and Jung, Friedrich and Yi, Dong and Herr, Wolfgang and Jung, Ernst Michael}, title = {Color mapping using ultrasound system-integrated perfusion software for evaluation of focal liver lesions: a possible first step for more independent reading}, series = {Journal of Gastrointestinal and Liver Diseases}, volume = {32}, journal = {Journal of Gastrointestinal and Liver Diseases}, number = {4}, issn = {1842-1121}, doi = {10.15403/jgld-4997}, pages = {479 -- 487}, abstract = {Aims To assess the value of using integrated parametric ultrasound software for contrast-enhanced ultrasonography (CEUS) of liver tumors. Methods 107 patients with liver tumors were studied. CEUS were performed to detect focal lesions. Parametric images were based on continuous CINE LOOPs, from the early-arterial phase (15 s) to the portal-venous phase (1 min) generated by perfusion software. The evaluations of the parametric images and their dignity for liver lesions were performed independently by an experienced and a less-experienced investigator. Computed tomography, magnetic resonance imaging scans or histological analysis were used as references. Results High parametric image quality were obtained in all patients. Among the patients, 44\% lesions were benign, 56\% were malignant. The experienced investigator correctly classified 46 of 47 (98\%) as benign, and 60 of 60 (100\%) as malignant tumors based on the parametric images. The less-experienced investigator correctly classified 39 of 47 (83\%) as benign, and 49 of 60 (82\%) malignant tumors, acheaving a high statistical accuracy of 98\% with this type of diagnostic. Conclusion Parametric imaging for grading the malignant degree of tumor may be a good complement to existing ultrasound techniques and was particularly helpful for improving the assessments of the less-experienced examiner.}, language = {en} } @article{ShiAllenmarkTheisingeretal., author = {Shi, Zhuanghua and Allenmark, Fredrik and Theisinger, Laura A. and Pistorius, Rasmus L. and Glasauer, Stefan and M{\"u}ller, Hermann J. and Falter-Wagner, Christine M.}, title = {Predictive Processing in ASD: The Atypical Iterative Prior Updating Account}, series = {Biological Psychiatry Global Open Science}, volume = {5}, journal = {Biological Psychiatry Global Open Science}, number = {3}, publisher = {Elsevier BV}, issn = {2667-1743}, doi = {10.1016/j.bpsgos.2025.100468}, pages = {9}, language = {en} }