@misc{SchneiderGlasauerBrandtetal., author = {Schneider, Erich and Glasauer, Stefan and Brandt, Thomas and Dieterich, Marianne}, title = {Nonlinear nystagmus processing causes torsional vor nonlinearity}, series = {Annals of the New York Academy of Sciences}, volume = {1004}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, pages = {500 -- 505}, language = {en} } @misc{StruppGlasauerJahnetal., author = {Strupp, Michael and Glasauer, Stefan and Jahn, Klaus and Schneider, Erich and Krafczyk, Siegbert and Brandt, Thomas}, title = {Eye movements and balance}, series = {Annals of the New York Academy of Sciences}, volume = {1004}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, pages = {352 -- 358}, language = {en} } @misc{HeuserSchulzSağlametal., author = {Heuser, Fabian and Schulz, Christian and Sağlam, Murat and Ramaioli, Cecilia and Heuberger, Maria and Wagner, Klaus J. and Jahn, Klaus and Schneider, Erich and Brandt, Thomas and Glasauer, Stefan and Lehnen, Nadine}, title = {Preventing opioid-induced nausea and vomiting: Rest your head and close your eyes?}, series = {PloS one}, volume = {12}, journal = {PloS one}, number = {3}, issn = {1932-6203}, doi = {10.1371/journal.pone.0173925}, pages = {e0173925}, language = {en} } @misc{SchoeberlPradhanIrvingetal., author = {Sch{\"o}berl, Florian and Pradhan, Cauchy and Irving, Stephanie and Buerger, Katharina and Xiong, Guoming and Kugler, G{\"u}nter and Kohlbecher, Stefan and Engmann, Julia and Werner, Philipp and Brendel, Matthias and Schneider, Erich and Perneczky, Robert and Jahn, Klaus and Foug{\`e}re, Christian la and Bartenstein, Peter and Brandt, Thomas and Dietrich, Marianne and Zwergal, Andreas}, title = {Real-space navigation testing differentiates between amyloid-positive and -negative aMCI}, series = {Neurology : official journal of the American Academy of Neurology}, volume = {94}, journal = {Neurology : official journal of the American Academy of Neurology}, number = {8}, issn = {1526-632X}, doi = {10.1212/WNL.0000000000008758}, pages = {e861 -- e873}, language = {en} } @misc{SchoeberlIrvingPradhanetal., author = {Sch{\"o}berl, Florian and Irving, Stephanie and Pradhan, Cauchy and Bardins, Stanislav and Trapp, Christoph and Schneider, Erich and Kugler, G{\"u}nter and Bartenstein, Peter and Dietrich, Marianne and Brandt, Thomas and Zwergal, Andreas}, title = {Prolonged allocentric navigation deficits indicate hippocampal damage in TGA}, series = {Neurology : official journal of the American Academy of Neurology}, volume = {92}, journal = {Neurology : official journal of the American Academy of Neurology}, number = {3}, issn = {0028-3878}, doi = {10.1212/WNL.0000000000006779}, pages = {e234 -- e243}, abstract = {Objective To investigate long-term recovery of allocentric and egocentric spatial orientation as a sensitive marker for hippocampal and extrahippocampal network function in transient global amnesia (TGA). Methods A group of 18 patients with TGA performed an established real-space navigation paradigm, requiring allo- and egocentric spatial orientation abilities, 3 days (postacute stage) and 3 months (follow-up) after symptom onset. Visual exploration behavior and navigation strategy were documented by a gaze-controlled, head-fixed camera. Allo- and egocentric spatial orientation performance was compared to that of 12 age-matched healthy controls. Navigation-induced brain activations were measured using [18F]-fluorodeoxyglucose-PET in a subgroup of 8 patients in the postacute stage and compared to those of the controls. Results In the postacute stage, the patients navigated worse and had higher error rates than controls in allocentric (p = 0.002), but not in egocentric, route planning (p = 0.30), despite complete recovery of verbal (p = 0.58) and figural memory (p = 0.11). Until follow-up, allocentric navigation deficits improved, but higher error rates and reduced use of shortcuts persisted (p < 0.0001). Patients still exhibited relatively more fixations of unique landmarks during follow-up (p = 0.05). PET measurements during the postacute stage showed increased navigation-induced brain activations in the right hippocampus, bilateral retrosplenial, parietal, and mesiofrontal cortices, and cerebellar dentate nucleus in patients compared to controls (p < 0.005). Conclusions Patients with TGA show selective and prolonged deficits of allocentric spatial orientation. Activations in right hippocampal and extrahippocampal hubs of the cerebral navigation network functionally substitute for the deficit in creating and updating the internal cognitive map in TGA.}, language = {en} } @misc{SpiegelClaassenTeufeletal., author = {Spiegel, Rainer and Claassen, Jens and Teufel, Julian and Bardins, Stanislav and Schneider, Erich and Lehrer, Nicole and Jahn, Klaus and Anciaes da Silva, F{\´a}bio and Hahn, Ales and Farahmand, Parvis and Brandt, Thomas and Strupp, Michael and Kalla, Roger}, title = {Resting in darkness improves downbeat nystagmus: evidence from an observational study}, series = {Annals of the New York Academy of Sciences}, volume = {1375}, journal = {Annals of the New York Academy of Sciences}, number = {1}, issn = {1749-6632}, doi = {10.1111/nyas.13172}, pages = {66 -- 73}, abstract = {Resting in an upright position during daytime decreases downbeat nystagmus (DBN). When measured in brightness only, that is, without intermitting exposure to darkness, it does not make a significant difference whether patients have previously rested in brightness or in darkness. In real-world scenarios, people are often exposed to brightness and darkness intermittently. The aim of this study was to analyze whether resting in brightness or resting in darkness was associated with a lower post-resting DBN after intermitting exposures to brightness and darkness. Eight patients were recorded with three-dimensional video-oculography in brightness and darkness conditions, each following two 2-h resting intervals under either brightness or darkness resting conditions. The dependent variable was DBN intensity, measured in mean slow phase velocity. A repeated measures ANOVA with the factors measurement condition (brightness vs. darkness), resting condition (brightness vs. darkness), and time (after first vs. second resting interval) showed a significant effect for the factor resting condition, where previous resting in darkness was associated with a significantly lower DBN relative to previous resting in brightness (P < 0.01). The clinical relevance is to advise patients with DBN to rest in darkness.}, language = {en} }