@inproceedings{WilczekTrieschmannSchulzeetal., author = {Wilczek, Sebastian and Trieschmann, Jan and Schulze, Julian and Sch{\"u}ngel, Edmund and Brinkmann, Ralf Peter and Derzsi, Aranka and Korolov, Ihor and Donk{\´o}, Zolt{\´a}n and Mussenbrock, Thomas}, title = {Confinement of highly energetic electron beams in low pressure capacitive discharges}, series = {Plasma Sciences (ICOPS), 2015 IEEE International Conference on, May 24-28, 2015, Antalya, Turkey}, booktitle = {Plasma Sciences (ICOPS), 2015 IEEE International Conference on, May 24-28, 2015, Antalya, Turkey}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4799-6974-6}, doi = {10.1109/PLASMA.2015.7179545}, language = {en} } @inproceedings{GallianTrieschmannMussenbrocketal., author = {Gallian, Sara and Trieschmann, Jan and Mussenbrock, Thomas and Hitchon, William N. G. and Brinkmann, Ralf Peter}, title = {Analytic model of the energy distribution for energetic electrons in HiPIMS}, series = {2015 IEEE International Conference on Plasma Sciences (ICOPS), 24 - 28 May 2015, Belek, Antalya, Turkey}, booktitle = {2015 IEEE International Conference on Plasma Sciences (ICOPS), 24 - 28 May 2015, Belek, Antalya, Turkey}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4799-6974-6}, doi = {10.1109/PLASMA.2015.7179892}, language = {en} } @inproceedings{SzeremleyMussenbrockBrinkmannetal., author = {Szeremley, Daniel and Mussenbrock, Thomas and Brinkmann, Ralf Peter and Zimmermanns, Marc and Rolfes, Ilona and Eremin, Denis}, title = {Comparison of a numerical and analytical model for the simulation of the mode propagation in a microwave driven plasma discharges}, series = {Plasma Sciences (ICOPS), 2015 IEEE International Conference on, May 24-28, 2015, Antalya, Turkey}, booktitle = {Plasma Sciences (ICOPS), 2015 IEEE International Conference on, May 24-28, 2015, Antalya, Turkey}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4799-6974-6}, doi = {10.1109/PLASMA.2015.7179679}, language = {en} } @inproceedings{WilczekTrieschmannBrinkmannetal., author = {Wilczek, Sebastian and Trieschmann, Jan and Brinkmann, Ralf Peter and Mussenbrock, Thomas and Schulze, Julian and Sch{\"u}ngel, Edmund and Derzsi, Aranka and Korolov, Ihor and Hartmann, Paul and Donk{\´o}, Zolt{\´a}n}, title = {Hysteresis effects and confinement of beam electrons in capacitive discharges}, series = {2016 IEEE International Conference on Plasma Science (ICOPS), Banff, Canada, June 19-23, 2016}, booktitle = {2016 IEEE International Conference on Plasma Science (ICOPS), Banff, Canada, June 19-23, 2016}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4673-9601-1}, doi = {10.1109/PLASMA.2016.7534342}, language = {en} } @inproceedings{WilczekBrinkmannMussenbrock, author = {Wilczek, Sebastian and Brinkmann, Ralf Peter and Mussenbrock, Thomas}, title = {Nonlinear electron resonance heating in asymmetric capacitive discharges}, series = {2016 IEEE International Conference on Plasma Science (ICOPS), Banff, Canada, June 19-23, 2016}, booktitle = {2016 IEEE International Conference on Plasma Science (ICOPS), Banff, Canada, June 19-23, 2016}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4673-9601-1}, doi = {10.1109/PLASMA.2016.7534107}, language = {en} } @misc{TarnawskaZoellnerNiermannetal., author = {Tarnawska, Lidia Lupina and Z{\"o}llner, Marvin Hartwig and Niermann, T. and Dietrich, Burkhart and Capellini, Giovanni and Thapa, Sarad and H{\"a}berlen, Maik and Lehmann, M. and Storck, Peter and Schr{\"o}der, Thomas}, title = {Zero Lattice Mismatch and Truly Single Crystalline ScN Buffer Layers for GaN Growth on Silicon}, series = {Applied Physics Letters}, volume = {107}, journal = {Applied Physics Letters}, number = {20}, issn = {1077-3118}, doi = {10.1063/1.4935856}, pages = {201907}, language = {en} } @misc{NiuCapelliniLupinaetal., author = {Niu, Gang and Capellini, Giovanni and Lupina, Grzegorz and Niermann, Tore and Salvalaglio, Marco and Marzegalli, Anna and Schubert, Markus Andreas and Zaumseil, Peter and Krause, Hans-Michael and Skibitzki, Oliver and Lehmann, Michael and Montalenti, Francesco and Xie, Ya-Hong and Schr{\"o}der, Thomas}, title = {Photodetection in hybrid single layer graphene/fully coherent Ge island nanostructures selectively grown on Si nano-tip patterns}, series = {ACS Applied Materials and Interfaces}, volume = {8}, journal = {ACS Applied Materials and Interfaces}, number = {3}, issn = {1944-8252}, pages = {2017 -- 2026}, language = {en} } @misc{ZaumseilSchubertYamamotoetal., author = {Zaumseil, Peter and Schubert, Markus Andreas and Yamamoto, Yuji and Skibitzki, Oliver and Capellini, Giovanni and Schr{\"o}der, Thomas}, title = {Misfit dislocation-free epitaxial growth of SiGe on compliant nanostructured Silicon}, series = {Solid State Phenomena}, volume = {242}, journal = {Solid State Phenomena}, issn = {1662-9779}, doi = {10.4028/www.scientific.net/SSP.242.402}, pages = {402 -- 407}, language = {en} } @misc{TaokaCapelliniDrieschetal., author = {Taoka, Noriyuki and Capellini, Giovanni and Driesch, Nils von den and Buca, Dan and Zaumseil, Peter and Schubert, Markus Andreas and Klesse, Wolfgang Matthias and Montanari, Michele and Schr{\"o}der, Thomas}, title = {Sn Migration Control at High Temperature Due to High Deposition Speed for Forming High Quality GeSn Layer}, series = {Applied Physics Express}, volume = {9}, journal = {Applied Physics Express}, number = {3}, issn = {1882-0786}, doi = {10.7567/APEX.9.031201}, pages = {031201}, language = {en} } @misc{NiuCapelliniSchubertetal., author = {Niu, Gang and Capellini, Giovanni and Schubert, Markus Andreas and Niermann, Tore and Zaumseil, Peter and Katzer, Jens and Krause, Hans-Michael and Skibitzki, Oliver and Lehmann, Michael and Xie, Ya-Hong and K{\"a}nel, Hans von and Schr{\"o}der, Thomas}, title = {Dislocation-free Ge nano-crystals via pattern dependent selective Ge heteroepitaxy on Si nano-tip wafers}, series = {Scientific Reports}, volume = {6}, journal = {Scientific Reports}, issn = {2045-2322}, doi = {10.1038/srep22709}, pages = {22709}, language = {en} } @misc{EngelhardKlempBehringeretal., author = {Engelhard, M. and Klemp, C. and Behringer, M. and Rudolph, A. and Skibitzki, Oliver and Zaumseil, Peter and Schr{\"o}der, Thomas}, title = {Characterization of reclaimed GaAs substrates and investigation of reuse for thin film InGaAlP LED epitaxial growth}, series = {Journal of Applied Physics}, volume = {120}, journal = {Journal of Applied Physics}, number = {4}, issn = {1089-7550}, doi = {10.1063/1.4955333}, pages = {045301}, language = {en} } @misc{NiuCapelliniHatamietal., author = {Niu, Gang and Capellini, Giovanni and Hatami, Fariba and Bartolomeo, Antonio di and Niermann, Tore and Hameed, Hussein Emad and Schubert, Markus Andreas and Krause, Hans-Michael and Zaumseil, Peter and Skibitzki, Oliver and Masselink, William T. and Lehmann, Michael and Xie, Ya-Hong and Schr{\"o}der, Thomas}, title = {Selective Epitaxy of InP on Si and Rectification in Graphene/InP/Si Hybrid Structure}, series = {ACS Applied Materials and Interfaces}, volume = {8}, journal = {ACS Applied Materials and Interfaces}, number = {40}, issn = {1944-8244}, doi = {10.1021/acsami.6b09592}, pages = {26948 -- 26955}, language = {en} } @misc{SkibitzkiCapelliniYamamotoetal., author = {Skibitzki, Oliver and Capellini, Giovanni and Yamamoto, Yuji and Zaumseil, Peter and Schubert, Markus Andreas and Schr{\"o}der, Thomas and Ballabio, Andrea and Bergamaschini, Roberto and Salvalaglio, Marco and Miglio, Leo and Montalenti, Francesco}, title = {RP-CVD growth of isolated Ge crystals and suspended layers on micrometric Si pillars}, series = {ACS Applied Materials and Interfaces}, volume = {8}, journal = {ACS Applied Materials and Interfaces}, number = {39}, issn = {1944-8244}, doi = {10.1021/acsami.6b07694}, pages = {26374 -- 26380}, language = {en} } @misc{SanaTetznerDabrowskietal., author = {Sana, Prabha and Tetzner, Henriette and Dabrowski, Jarek Marek and Tarnawska, Lidia Lupina and Costina, Ioan and Thapa, Sarad and Storck, Peter and Schr{\"o}der, Thomas and Z{\"o}llner, Marvin Hartwig}, title = {Growth of ScN(111) on Sc₂O₃ (111) for GaN integration on Si(111): Experiment and ab initio calculations}, series = {Journal of Applied Physics}, volume = {120}, journal = {Journal of Applied Physics}, issn = {1089-7550}, doi = {10.1063/1.4963826}, pages = {135103}, language = {en} } @misc{SchlykowKlesseNiuetal., author = {Schlykow, Viktoria and Klesse, Wolfgang Matthias and Niu, Gang and Taoka, Noriyuki and Yamamoto, Yuji and Skibitzki, Oliver and Barget, M. R. and Zaumseil, Peter and K{\"a}nel, Hans von and Schubert, Markus Andreas and Capellini, Giovanni and Schroeder, Thomas}, title = {Selective growth of fully relaxed GeSn nano-islands by nanoheteroepitaxy on patterned Si(001)}, series = {Applied Physics Letters}, volume = {109}, journal = {Applied Physics Letters}, number = {20}, issn = {1077-3118}, doi = {10.1063/1.4967500}, pages = {202102}, language = {en} } @inproceedings{HinzeGruetzmannHoeckneretal., author = {Hinze, Thomas and Gr{\"u}tzmann, Konrad and H{\"o}ckner, Benny and Sauer, Peter and Hayat, Sikander}, title = {Categorised Counting Mediated by Blotting Membrane Systems for Particle-Based Data Mining and Numerical Algorithms}, series = {Membrane computing, 15th International Conference, CMC 2014 Prague, Czech Republic, August 20-22, 2014}, booktitle = {Membrane computing, 15th International Conference, CMC 2014 Prague, Czech Republic, August 20-22, 2014}, editor = {Gheorghe, Marian and Rozenberg, Grzegorz and Salomaa, Arto and Sos{\´i}k, Petr and Zandron, Claudio}, publisher = {Springer}, address = {Cham [u.a.]}, isbn = {978-3-319-14369-9}, pages = {241 -- 257}, language = {en} } @inproceedings{HinzeKirkiciSaueretal., author = {Hinze, Thomas and Kirkici, Korcan and Sauer, Patricia and Sauer, Peter and Behre, J{\"o}rn}, title = {Membrane Computing Meets Temperature: A Thermoreceptor Model as Molecular Slide Rule with Evolutionary Potential}, series = {Membrane Computing, 16th International Conference, CMC 2015, Valencia, Spain, August 17-21, 2015,}, booktitle = {Membrane Computing, 16th International Conference, CMC 2015, Valencia, Spain, August 17-21, 2015,}, editor = {Rozenberg, Grzegorz and Salomaa, Arto and Sempere, Jos{\´e} M. and Zandron, Claudio}, publisher = {Springer Verlag}, address = {Cham [u.a.]}, isbn = {978-3-319-28474-3}, pages = {215 -- 235}, language = {en} } @inproceedings{SchneiderHirschWechleretal., author = {Schneider, Anna and Hirsch, Florian and Wechler, Klaus-Peter and Raab, Alexandra and Raab, Thomas}, title = {Mapping a paleosurface and archaeological site location in an inland dune area in Brandenburg, Germany}, series = {European Geosciences Union, General Assembly 2017, Vienna, Austria}, booktitle = {European Geosciences Union, General Assembly 2017, Vienna, Austria}, publisher = {European Geophysical Society}, address = {Katlenburg-Lindau}, abstract = {Mapping and visualizing the position of archaeological remains in the surface relief provides important basic information for archaeological survey design and interpretation. Geomorphological processes in (pre)history can have resulted in a modification of the local relief around archaeological sites, especially in areas that are prone to sediment erosion and relocation, so that models of past surfaces are necessary for a correct interpretation of archaeological survey results. In this study, we combined terrestrial survey and remote sensing methods to reconstruct the palaeorelief around two archaeological excavation sites in an inland dune area in southern Brandenburg, Germany. Remains from two Mesolithic hunter-gatherer camps were documented in archaeological excavations and found to be associated with a buried soil horizon. To gather information on the relief of the buried soil surface, we used a combination of sedimentological and pedological profile description of archaeological survey trenches and geophysical prospection with Ground-Penetrating Radar; supplemented by microdrone photography and photogrammetry, GPS surveys and analysis of LIDAR-based elevation models. A digital elevation model of the buried surface was created by combining point data from these sources. The buried surface morphology and the position of the archeological remains within the reconstructed landscape were analyzed in GIS. The comparison of the generated paleosurface model with the recent surface elevation model shows that sand remobilization resulted in a considerable reshaping of the relief. Analysis of the buried surface model further shows that the relief position of the two archaeological sites in the study area was considerably more prominent in relation to the corresponding buried soil surface than in relation to the recent surface morphology. Results affirm the importance of considering Holocene relief modifications in archaeological surveys.}, language = {en} } @inproceedings{SchneiderHirschWechleretal., author = {Schneider, Anna and Hirsch, Florian and Wechler, Klaus-Peter and Raab, Alexandra and Raab, Thomas}, title = {Mapping a palaeosurface and archaeological site location in an anthropogenic drift sand area}, series = {ICLEA Final Symposium 2017, Human Impact and Landscape Evolution in the Southern Baltic Lowlands, Abstract Volume \& Excursion Guide}, booktitle = {ICLEA Final Symposium 2017, Human Impact and Landscape Evolution in the Southern Baltic Lowlands, Abstract Volume \& Excursion Guide}, editor = {Schwab, Markus and Błaszkiewicz, Mirek and Raab, Thomas and Wilmking, Martin and Brauer, Achim}, doi = {10.2312/GFZ.b103-17037}, pages = {152 -- 154}, language = {en} } @incollection{KlimczakZoglauer, author = {Klimczak, Peter and Zoglauer, Thomas}, title = {Einleitung - Was heißt Logik anwenden?}, series = {Logik in den Wissenschaften}, booktitle = {Logik in den Wissenschaften}, editor = {Klimczak, Peter and Zoglauer, Thomas}, publisher = {Mentis Verlag}, address = {M{\"u}nster}, isbn = {978-3-95743-108-0}, pages = {7 -- 17}, language = {de} } @inproceedings{BeirowKuehhornFigaschewskyetal., author = {Beirow, Bernd and K{\"u}hhorn, Arnold and Figaschewsky, Felix and H{\"o}nisch, Peter and Giersch, Thomas and Schrape, Sven}, title = {Model Update and Validation of a Mistuned High Pressure Compressor Blisk}, series = {Proceedings of ISABE 2017, ISABE-2017-22568, Manchester, September 3.-8., 2017}, booktitle = {Proceedings of ISABE 2017, ISABE-2017-22568, Manchester, September 3.-8., 2017}, publisher = {ISABE}, pages = {14}, language = {en} } @misc{DakshaDerzsiWilczeketal., author = {Daksha, Manaswi and Derzsi, Aranka and Wilczek, Sebastian and Trieschmann, Jan and Mussenbrock, Thomas and Awakowicz, Peter and Donk{\´o}, Zolt{\´a}n and Schulze, Julian}, title = {The Effect of Realistic Heavy Particle Induced Secondary Electron Emission Coefficients on the Electron Power Absorption Dynamics in Single- and Dual-Frequency CCPs}, series = {Plasma Sources Science and Technology}, volume = {26}, journal = {Plasma Sources Science and Technology}, number = {8}, issn = {1361-6595}, doi = {10.1088/1361-6595/aa7c88}, pages = {085006}, language = {en} } @misc{EreminBrinkmannMussenbrock, author = {Eremin, Denis and Brinkmann, Ralf Peter and Mussenbrock, Thomas}, title = {Observations of Surface Mode Influence on Plasma Uniformity in PIC/MCC Simulations of Large Capacitive Discharges}, series = {Plasma Processes and Polymers}, volume = {14}, journal = {Plasma Processes and Polymers}, number = {4-5}, issn = {1612-8869}, doi = {10.1002/ppap.201600164}, language = {en} } @misc{SchmidtTrieschmannBrinkmannetal., author = {Schmidt, Frederik and Trieschmann, Jan and Brinkmann, Ralf Peter and Mussenbrock, Thomas}, title = {Nonlinear interaction of capacitive discharges and power matching networks}, series = {Bulletin of the American Physical Society}, volume = {62}, journal = {Bulletin of the American Physical Society}, number = {10}, issn = {0003-0503}, language = {en} } @misc{KammererJahnWinteretal., author = {Kammerer, Sarah and Jahn, Stephan Wenzel and Winter, Elke and Eidenhammer, Sylvia and Rezania, Simin and Regitnig, Peter and Pichler, Martin and Schreibmayer, Wolfgang and Bauernhofer, Thomas}, title = {Critical evaluation of KCNJ3 gene product detection in human breast cancer: MRNA in situ hybridisation is superior to immunohistochemistry}, series = {Journal of Clinical Pathology}, volume = {69}, journal = {Journal of Clinical Pathology}, number = {12}, issn = {1472-4146}, doi = {10.1136/jclinpath-2016-203798}, pages = {1116 -- 1121}, abstract = {Increased expression levels of KCNJ3 have been correlated with lymph node metastases and poor prognosis in patients with breast cancer, suggesting a prognostic role of KCNJ3. We aimed to establish protocols for the detection of KCNJ3 in formalin-fixed, paraffin-embedded (FFPE) breast cancer tissue. Several antibodies were tested for sensitivity and specificity by western blot, followed by optimisation of the immunohistochemistry (IHC) procedure and establishment of KCNJ3 mRNA in situ hybridisation (ISH). Methods were validated by processing 15 FFPE breast cancer samples for which microarray data were available. Spearman's rank correlation analysis resulted in borderline significant correlation for IHC versus ISH (rS: 0.625; p<0.05) and IHC versus microarray (rS: 0.668; p<0.01), but in significant correlation for ISH versus microarray (rS: 0.861; p<0.001). The ISH method was superior to IHC, regarding robustness, sensitivity and specificity and will aid to further study expression levels of KCNJ3 in both malignant and physiological conditions.}, language = {en} } @misc{KammererSokolowskiHackletal., author = {Kammerer, Sarah and Sokolowski, Armin Andreas and Hackl, Hubert and Platzer, Dieter and Jahn, Stephan Wenzel and El-Heliebi, Amin and Schwarzenbacher, Daniela and Stiegelbauer, Verena and Pichler, Martin and Rezania, Simin and Fiegl, Heidelinde and Peintinger, Florentia and Regitnig, Peter and H{\"o}fler, Gerald and Schreibmayer, Wolfgang and Bauernhofer, Thomas}, title = {KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients}, series = {OncoTarget : open access impact journal}, volume = {7}, journal = {OncoTarget : open access impact journal}, number = {51}, doi = {10.18632/oncotarget.13224}, pages = {84705 -- 84717}, abstract = {Numerous studies showed abnormal expression of ion channels in different cancer types. Amongst these, the potassium channel gene KCNJ3 (encoding for GIRK1 proteins) has been reported to be upregulated in tumors of patients with breast cancer and to correlate with positive lymph node status. We aimed to study KCNJ3 levels in different breast cancer subtypes using gene expression data from the TCGA, to validate our findings using RNA in situ hybridization in a validation cohort (GEO ID GSE17705), and to study the prognostic value of KCNJ3using survival analysis. In a total of > 1000 breast cancer patients of two independent data sets we showed a) that KCNJ3 expression is upregulated in tumor tissue compared to corresponding normal tissue (p < 0.001), b) that KCNJ3 expression is associated with estrogen receptor (ER) positive tumors (p < 0.001), but that KCNJ3 expression is variable within this group, and c) that ER positive patients with high KCNJ3 levels have worse overall (p < 0.05) and disease free survival probabilities (p < 0.01), whereby KCNJ3 is an independent prognostic factor (p <0.05). In conclusion, our data suggest that patients with ER positive breast cancer might be stratified into high risk and low risk groups based on the KCNJ3 levels in the tumor.}, language = {en} } @misc{KotlarskiSzaboHerreraetal., author = {Kotlarski, Sven and Szabo, Peter and Herrera, Sixto and R{\"a}ty, Olle and Keuler, Klaus and Soares, Pedro and Cardoso, Rita M. and Bosshard, Thomas and Pag{\´e}, Christian and Boberg, Fredrik and Guti{\´e}rrez, Jos{\´e} and Isotta, Francesco and Jaczewski, Adam and Kreienkamp, Frank and Liniger, Mark and Lussana, Cristian and Pianko-Kluczyńska, Krystyna}, title = {Observational uncertainty and regional climate model evaluation: A pan-European perspective}, series = {International journal of climatology}, volume = {39}, journal = {International journal of climatology}, number = {9}, issn = {1097-0088}, doi = {10.1002/joc.5249}, pages = {3730 -- 3749}, language = {en} } @misc{TrieschmannRiesBibinovetal., author = {Trieschmann, Jan and Ries, Stefan and Bibinov, Nikita and Awakowicz, Peter and Mr{\´a}z, Stanislav and Schneider, Jochen M. and Mussenbrock, Thomas}, title = {Combined experimental and theoretical description of direct current magnetron sputtering of Al by Ar and Ar/N₂ plasma}, series = {Plasma Sources Science and Technology}, volume = {27}, journal = {Plasma Sources Science and Technology}, number = {5}, doi = {10.1088/1361-6595/aac23e}, pages = {14}, language = {en} } @misc{FroemmelLehmannRoedigeretal., author = {Fr{\"o}mmel, Ulrike and Lehmann, Werner and R{\"o}diger, Stefan and B{\"o}hm, Alexander and Nitschke, J{\"o}rg and Weinreich, J{\"o}rg and Groß, Julia and Roggenbuck, Dirk and Zinke, Olaf and Ansorge, Hermann and Vogel, Steffen and Klemm, Per and Wex, Thomas and Schr{\"o}der, Christian and Wieler, Lothar H. and Schierack, Peter}, title = {Adhesion of human and animal Escherichia coli strains in association with their virulence-associated genes and phylogenetic origins}, series = {Applied and environmental microbiology}, volume = {79}, journal = {Applied and environmental microbiology}, number = {19}, issn = {1098-5336}, doi = {10.1128/AEM.01384-13}, pages = {5814 -- 5829}, abstract = {Intestinal colonization is influenced by the ability of the bacterium to inhabit a niche, which is based on the expression of colonization factors. Escherichia coli carries a broad range of virulence-associated genes (VAGs) which contribute to intestinal (inVAGs) and extraintestinal (exVAGs) infection. Moreover, initial evidence indicates that inVAGs and exVAGs support intestinal colonization. We developed new screening tools to genotypically and phenotypically characterize E. coli isolates originating in humans, domestic pigs, and 17 wild mammal and avian species. We analyzed 317 isolates for the occurrence of 44 VAGs using a novel multiplex PCR microbead assay (MPMA) and for adhesion to four epithelial cell lines using a new adhesion assay. We correlated data for the definition of new adhesion genes. inVAGs were identified only sporadically, particularly in roe deer (Capreolus capreolus) and the European hedgehog ( Erinaceus europaeus). The prevalence of exVAGs depended on isolation from a specific host. Human uropathogenic E. coli isolates carried exVAGs with the highest prevalence, followed by badger (Meles meles) and roe deer isolates. Adhesion was found to be very diverse. Adhesion was specific to cells, host, and tissue, though it was also unspecific. Occurrence of the following VAGs was associated with a higher rate of adhesion to one or more cell lines: afa-dra, daaD, tsh, vat, ibeA, fyuA, mat, sfa-foc, malX, pic, irp2, and papC. In summary, we established new screening methods which enabled us to characterize large numbers of E. coli isolates. We defined reservoirs for potential pathogenic E. coli. We also identified a very broad range of colonization strategies and defined potential new adhesion genes.}, language = {en} } @misc{FroemmelBoehmNitschkeetal., author = {Fr{\"o}mmel, Ulrike and B{\"o}hm, Alexander and Nitschke, J{\"o}rg and Weinreich, J{\"o}rg and Groß, Julia and R{\"o}diger, Stefan and Wex, Thomas and Ansorge, Hermann and Zinke, Olaf and Schr{\"o}der, Christian and Roggenbuck, Dirk and Schierack, Peter}, title = {Adhesion patterns of commensal and pathogenic Escherichia coli from humans and wild animals on human and porcine epithelial cell lines}, series = {Gut Pathogens}, volume = {5}, journal = {Gut Pathogens}, number = {31}, issn = {1757-4749}, doi = {10.1186/1757-4749-5-31}, pages = {8}, abstract = {Abstract BACKGROUND: Different strategies of colonization or infection by E. coli result in formation of certain adhesion patterns which help also in classifying intestinal E. coli into pathotypes. Little is known about adhesion patterns and host- and tissue adaption of commensal E. coli and about E. coli originating in clinically healthy hosts carrying pathotype-specific virulence-associated genes. FINDINGS: Adhesion pattern of E. coli (n = 282) from humans and from 18 animal species were verified on intestinal human Caco-2 and porcine IPEC-J2 cells and, furthermore, for comparison on human urinary bladder 5637, porcine kidney PK-15 epithelial and HEp-2 cells. The analysis was carried out on 150,000 images of adhesion assays.Adhesion patterns were very diverse; 88 isolates were completely non-adherent, whereas 194 adhered to at least one cell line with the dominant adhesion patterns "diffusely distributed" and "microcolony formation". Adhesion patterns "chains" and "clumps" were also visible. Chain formation was mediated by the presence of epithelial cells. Clump formation was very specific on only the 5637 cell line. All enteropathogenic (eae+) E. coli (EPEC; n = 14) were able to form microcolonies which was cell line specific for each isolate. Most EPEC formed microcolonies on intestinal IPEC-J2 and Caco-2 but several also on urinary tract cells. Shigatoxin-producing (stx+) E. coli (n = 10) showed no specific adhesion patterns. CONCLUSIONS: E. coli isolates were highly diverse. Commensal and pathogenic isolates can adhere in various forms, including diffuse distribution, microcolonies, chains and clumps. Microcolony formation seems to be a global adhesion strategy also for commensal E. coli.}, language = {en} } @misc{NalliSommaAndreolietal., author = {Nalli, Cecilia and Somma, Valentina and Andreoli, Laura and B{\"u}ttner, Thomas and Schierack, Peter and Mahler, Michael and Roggenbuck, Dirk and Tincani, Angela}, title = {Anti-phospholipid IgG antibodies detected by line immunoassay differentiate patients with anti-phospholipid syndrome and other autoimmune diseases}, series = {Autoimmunity Highlights}, volume = {9}, journal = {Autoimmunity Highlights}, number = {1}, issn = {2038-3274}, doi = {10.1007/s13317-018-0106-0}, pages = {11}, language = {en} } @misc{SchierackRoedigerKolendaetal., author = {Schierack, Peter and R{\"o}diger, Stefan and Kolenda, Rafał and Hiemann, Rico and Berger, Enrico and Grzymajlo, Krzysztof and Swidsinski, Alexander and Juretzek, Thomas and Meissner, Dirk and Mydlak, Karsten and Reinhold, Dirk and Nolan, Lisa K. and Roggenbuck, Dirk}, title = {Species-specific and pathotype-specific binding of bacteria to zymogen granule membrane glycoprotein 2 (GP2)}, series = {Gut}, volume = {64}, journal = {Gut}, number = {3}, issn = {1468-3288}, doi = {10.1136/gutjnl-2014-307854}, pages = {517 -- 519}, language = {en} } @misc{GuentherGrothSchieracketal., author = {Guenther, Sebastian and Groth, Ingrid and Schierack, Peter and Grabley, Susanne and Munder, Thomas}, title = {Direct detection of Kitasatospora species with a chaperone oligonucleotide microarray method lacking PCR amplification}, series = {Journal of basic microbiology}, volume = {48}, journal = {Journal of basic microbiology}, number = {4}, issn = {1521-4028}, doi = {10.1002/jobm.200800038}, pages = {315 -- 318}, language = {en} } @misc{RoggenbuckBorghiSommaetal., author = {Roggenbuck, Dirk and Borghi, Maria Orietta and Somma, Valentina and B{\"u}ttner, Thomas and Schierack, Peter and Hanack, Katja and Grossi, Claudia and Bodio, Caterina and Macor, Paolo and Landenberg, Philipp von and Boccellato, Francesco and Mahler, Michael and Meroni, Pier Luigi}, title = {Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers}, series = {Arthritis Research \& Therapy}, volume = {18}, journal = {Arthritis Research \& Therapy}, number = {111}, issn = {1465-9913}, doi = {10.1186/s13075-016-1018-x}, pages = {14}, language = {en} } @misc{WilczekTrieschmannSchulzeetal., author = {Wilczek, Sebastian and Trieschmann, Jan and Schulze, Julian and Donko, Zoltan and Brinkmann, Ralf Peter and Mussenbrock, Thomas}, title = {Disparity between current and voltage driven capacitively coupled radio frequency discharges}, series = {Plasma Sources Science and Technology}, volume = {27}, journal = {Plasma Sources Science and Technology}, number = {12}, issn = {1361-6595}, doi = {10.1088/1361-6595/aae5c1}, pages = {12}, language = {en} } @misc{BergerYouLeeetal., author = {Berger, Birk and You, Kwangho and Lee, Hyo-Chang and Mussenbrock, Thomas and Awakowicz, Peter and Schulze, Julian}, title = {Observation of the generation of multiple electron beams during a single sheath expansion phase in capacitive RF plasmas}, series = {Plasma Sources Science and Technology}, volume = {27}, journal = {Plasma Sources Science and Technology}, number = {12}, issn = {1361-6595}, doi = {10.1088/1361-6595/aaefc7}, pages = {5}, language = {en} } @misc{GibsonDonkoAlelyanietal., author = {Gibson, Andrew R. and Donk{\´o}, Zolt{\´a}n and Alelyani, Layla and Bischoff, Lena and H{\"u}bner, Gerrit and Bredin, J{\´e}r{\^o}me and Doyle, Scott and Korolov, Ihor and Niemi, Kari and Mussenbrock, Thomas and Hartmann, Peter and Dedrick, James P. and Schulze, Julian and Gans, Timo and O'Connell, Deborah}, title = {Disrupting the spatio-temporal symmetry of the electron dynamics in atmospheric pressure plasmas by voltage waveform tailoring}, series = {Plasma Sources Science and Technology}, volume = {28}, journal = {Plasma Sources Science and Technology}, number = {1}, issn = {1361-6595}, doi = {10.1088/1361-6595/aaf535}, pages = {7}, language = {en} } @misc{BischoffHuebnerKorolovetal., author = {Bischoff, Lena and H{\"u}bner, Gerrit and Korolov, Ihor and Donk{\´o}, Zolt{\´a}n and Hartmann, Peter and Gans, Timo and Held, Julian and Schulz-von der Gathen, Volker and Liu, Yue and Mussenbrock, Thomas and Schulze, Julian}, title = {Experimental and computational investigations of electron dynamics in micro atmospheric pressure radio-frequency plasma jets operated in He/N2 mixtures}, series = {Plasma Sources Science and Technology}, volume = {27}, journal = {Plasma Sources Science and Technology}, number = {12}, issn = {1361-6595}, doi = {10.1088/1361-6595/aaf35d}, pages = {16}, language = {en} } @misc{LiebschRoedigerBoehmetal., author = {Liebsch, Claudia and R{\"o}diger, Stefan and B{\"o}hm, Alexander and Nitschke, J{\"o}rg and Weinreich, J{\"o}rg and Fruth, Angelika and Roggenbuck, Dirk and Lehmann, Werner and Schedler, Uwe and Juretzek, Thomas and Schierack, Peter}, title = {Solid-phase microbead array for multiplex O-serotyping of Escherichia coli}, series = {Microchimica Acta}, volume = {184}, journal = {Microchimica Acta}, number = {5}, issn = {0026-3672}, doi = {10.1007/s00604-017-2088-4}, pages = {1405 -- 1415}, language = {en} } @misc{BeirowKuehhornFigaschewskyetal., author = {Beirow, Bernd and K{\"u}hhorn, Arnold and Figaschewsky, Felix and H{\"o}nisch, Peter and Giersch, Thomas and Schrape, Sven}, title = {Model update and validation of a mistuned high-pressure compressor blisk}, series = {The Aeronautical Journal}, volume = {123}, journal = {The Aeronautical Journal}, number = {1260}, issn = {2059-6464}, doi = {10.1017/aer.2018.149}, pages = {230 -- 247}, abstract = {In order to prepare an advanced 4-stage high-pressure compressor rig test campaign, details regarding both accomplishment and analysis of preliminary experiments are provided in this paper. The superior objective of the research project is to contribute to a reliable but simultaneously less conservative design of future high pressure blade integrated disks (blisk). It is planned to achieve trend-setting advances based on a close combination of both numerical and experimental analyses. The analyses are focused on the second rotor of this research compressor, which is the only one being manufactured as blisk. The comprehensive test program is addressing both surge and forced response analyses e.g. caused by low engine order excitation. Among others the interaction of aeroelastics and blade mistuning is demanding attention in this regard. That is why structural models are needed, allowing for an accurate forced response prediction close to reality. Furthermore, these models are required to support the assessment of blade tip timing (BTT) data gathered in the rig tests and strain gauge (s/g) data as well. To gain the maximum information regarding the correlation between BTT data, s/g-data and pressure gauge data, every blade of the second stage rotor (28 blades) is applied with s/g. However, it is well known that s/g on blades can contribute additional mistuning that had to be considered upon updating structural models. Due to the relevance of mistuning, efforts are made for its accurate experimental determination. Blade-by-blade impact tests according to a patented approach are used for this purpose. From the research point of view, it is most interesting to determine both the effect s/g-instrumentation and assembling the compressor stages on blade frequency mistuning. That is why experimental mistuning tests carried out immediately after manufacturing the blisk are repeated twice, namely, after s/g instrumentation and after assembling. To complete the pre-test program, the pure mechanical damping and modal damping ratios dependent on the ambient pressure are experimentally determined inside a pressure vessel. Subsequently the mistuning data gained before is used for updating subset of nominal system mode (SNM) models. Aerodynamic influence coefficients (AICs) are implemented to take aeroelastic interaction into account for forced response analyses. Within a comparison of different models, it is shown for the fundamental flap mode (1F) that the s/g instrumentation significantly affects the forced response, whereas the impact of assembling the compressor plays a minor role.}, language = {en} } @misc{KorolovDonkoHuebneretal., author = {Korolov, Ihor and Donko, Zoltan and H{\"u}bner, Gerrit and Bischoff, Lena and Hartmann, Peter and Gans, Timo and Liu, Yue and Mussenbrock, Thomas and Schulze, Julian}, title = {Control of electron dynamics, radical and metastable species generation in atmospheric pressure RF plasma jets by Voltage Waveform Tailoring}, series = {Plasma Sources Science and Technology}, volume = {28}, journal = {Plasma Sources Science and Technology}, number = {9}, issn = {0963-0252}, doi = {10.1088/1361-6595/ab38ea}, pages = {16}, language = {en} } @misc{SchneiderSimonTaeschneretal., author = {Schneider, Robert and Simon, Sylvio and T{\"a}schner, Dirk and Hernschier, Stephan and Rieder, Thomas and Magister, Jan and Biegel, Peter}, title = {Untersuchungen zur Wirkung von Kreisformabweichung und Exzentrizit{\"a}t auf das Laufverhalten von Tragrollen in Hochleistungsgurtf{\"o}rderanlagen}, series = {8. Kolloquium F{\"o}rdertechnikim Bergbau - Tagungsband}, journal = {8. Kolloquium F{\"o}rdertechnikim Bergbau - Tagungsband}, publisher = {Papierflieger Verlag GmbH}, address = {Clausthal-Zellerfeld, 2018}, isbn = {978-3-86948-621-5}, pages = {99 -- 110}, abstract = {W{\"a}hrend im Tagebau fr{\"u}her das Augenmerk prim{\"a}r auf einen zuverl{\"a}ssigen und wirtschaftlichen Abbau und Transport von Rohstoffen gerichtet war, spielen heutzutage noch einige andere Aspekte eine entscheidende Rolle. Da die Abbaugebiete immer weiter in besiedelte Gegenden vordringen und die Vorgaben im Umweltschutz sich versch{\"a}rfen, ist der Betreiber in zunehmendem Maße bestrebt, unter anderem die Ger{\"a}uschemissionen der Tagebaugroßger{\"a}te zu senken. Da sich speziell Gurtf{\"o}rderanlagen im Bereich des Vorschnitts {\"u}ber große Entfernungen erstrecken und an den R{\"a}ndern der Tagebaue verlaufen, tragen diese zu einem großen Teil zur Ger{\"a}uschemission bei. Tragrollen sind oft zu Tausenden in den F{\"o}rderanlagen verbaut und bei der akustischen Wirkung von entscheidender Bedeutung. Um eine Gesundheitsgef{\"a}hrdung f{\"u}r die besch{\"a}ftigten Mitarbeiter durch L{\"a}rm zu vermeiden und die Auswirkungen auf angrenzende Siedlungen auf ein Mindestmaß zu begrenzen, existieren gesetzliche Vorschriften und Richtlinien. Die Gesetze und Verordnungen zum Umweltschutz und Arbeitsschutz sollen eine Reduzierung der L{\"a}rmimmissionen erreichen. Laut den Immissionsrichtwerten1 der Technischen Anleitung zum Schutz gegen L{\"a}rm (TA L{\"a}rm) darf nachts in Kerngebieten, Dorf- und Mischgebieten der Beurteilungspegel von 45 dB(A) nicht {\"u}berschritten werden, in reinen Wohngebieten liegt die Grenze sogar bei 35 dB(A). Zum Vergleich: Eine leise Unterhaltung oder leise Musik wird mit einem Schalldruckpegel von 40 dB(A) angegeben. Der durch den Betrieb der Gurtf{\"o}rderanlagen entstehende meterbezogene Schallleistungspegel LW betr{\"a}gt im Durchschnitt etwa 80 bis 100 dB(A). Durch Reduktion der Schallemission k{\"o}nnten die Planungen der Streckenverl{\"a}ufe optimiert werden, was zu wirtschaftlichen Einsparungen f{\"u}hrt. Weiterhin ist, wenn die f{\"u}r Tagebauanlagen zu beachtenden Richtwerte eingehalten werden, auch die Genehmigung f{\"u}r die Einrichtung und den Betrieb solcher Anlagen einfacher abzusichern. Um genaue Kenntnisse {\"u}ber die Schallemission von Tragrollen zu erlangen, wurde in Zusammenarbeit der ehemaligen VEM AG (jetzt LEAG) und der ehemaligen Hochschule Lausitz (jetzt BTU Cottbus-Senftenberg) ein Tragrollenpr{\"u}fstand entwickelt. Im Rahmen einer Baugruppenpr{\"u}fung auf diesem Pr{\"u}fstand werden akustische und mechanische Kenngr{\"o}ßen von Tragrollen untersucht. Bestandteile dieser Untersuchungen sind: - Hochfahrpr{\"u}fl{\"a}ufe - Dabei wird eine Tragrolle unter Pr{\"u}flast auf eine Umfangsgeschwindigkeit von 10 m/s beschleunigt und der Schalldruckpegel aufgezeichnet. Dies erm{\"o}glicht die Berechnung der Schallemission in Abh{\"a}ngigkeit von der Umfangsgeschwindigkeit. - Ermittlung des Abklingverhaltens - Durch Anschlagversuche wird das Eigenschwing- und D{\"a}mpfungsverhalten einer Tragrolle erfasst. - Erfassung der Tragrollengeometrie - Die pr{\"a}zise Beschreibung der Geometrie des Tragrollenmantels erm{\"o}glicht R{\"u}ckschl{\"u}sse auf m{\"o}gliche Anregungsursachen.}, language = {de} } @misc{SimonBiegelHernschieretal., author = {Simon, Sylvio and Biegel, Peter and Hernschier, Stephan and T{\"a}schner, Dirk and Rieder, Thomas and Magister, Jan and Schneider, Robert and Fritsch, Tim}, title = {10 Jahre Tragrollenpr{\"u}fstand : Vortragsband zum Festkolloquium am 18. Oktober 2017}, publisher = {BTU}, address = {Senftenberg}, doi = {10.5281/zenodo.3457376}, pages = {118}, abstract = {Tagungsband mit 6 Vortr{\"a}gen im Rahmen des Jubil{\"a}umskolliquiums}, language = {de} } @misc{KorolovLeimkuehlerBoekeetal., author = {Korolov, Ihor and Leimk{\"u}hler, Marc and Boeke, Marc and Donk{\´o}, Zoltan and Schulz-von der Gathen, Volker and Bischoff, Lena and H{\"u}bner, Gerrit and Hartmann, Peter and Gans, Timo and Liu, Yue and Mussenbrock, Thomas and Schulze, Julian}, title = {Helium metastable species generation in atmospheric pressure RF plasma jets driven by tailored voltage waveforms in mixtures of He and N 2}, series = {Journal of Physics D: Applied Physics}, volume = {53}, journal = {Journal of Physics D: Applied Physics}, issn = {1361-6463}, doi = {10.1088/1361-6463/ab6d97}, pages = {18}, language = {en} } @misc{WilczekSchulzeBrinkmannetal., author = {Wilczek, Sebastian and Schulze, Julian and Brinkmann, Ralf Peter and Donk{\´o}, Zoltan and Trieschmann, Jan and Mussenbrock, Thomas}, title = {Electron dynamics in low pressure capacitively coupled radio frequency discharges}, series = {Journal of Applied Physics}, volume = {127}, journal = {Journal of Applied Physics}, number = {18}, doi = {10.1063/5.0003114.1}, language = {en} } @misc{SchoeberlPradhanIrvingetal., author = {Sch{\"o}berl, Florian and Pradhan, Cauchy and Irving, Stephanie and Buerger, Katharina and Xiong, Guoming and Kugler, G{\"u}nter and Kohlbecher, Stefan and Engmann, Julia and Werner, Philipp and Brendel, Matthias and Schneider, Erich and Perneczky, Robert and Jahn, Klaus and Foug{\`e}re, Christian la and Bartenstein, Peter and Brandt, Thomas and Dietrich, Marianne and Zwergal, Andreas}, title = {Real-space navigation testing differentiates between amyloid-positive and -negative aMCI}, series = {Neurology : official journal of the American Academy of Neurology}, volume = {94}, journal = {Neurology : official journal of the American Academy of Neurology}, number = {8}, issn = {1526-632X}, doi = {10.1212/WNL.0000000000008758}, pages = {e861 -- e873}, language = {en} } @misc{SchoeberlIrvingPradhanetal., author = {Sch{\"o}berl, Florian and Irving, Stephanie and Pradhan, Cauchy and Bardins, Stanislav and Trapp, Christoph and Schneider, Erich and Kugler, G{\"u}nter and Bartenstein, Peter and Dietrich, Marianne and Brandt, Thomas and Zwergal, Andreas}, title = {Prolonged allocentric navigation deficits indicate hippocampal damage in TGA}, series = {Neurology : official journal of the American Academy of Neurology}, volume = {92}, journal = {Neurology : official journal of the American Academy of Neurology}, number = {3}, issn = {0028-3878}, doi = {10.1212/WNL.0000000000006779}, pages = {e234 -- e243}, abstract = {Objective To investigate long-term recovery of allocentric and egocentric spatial orientation as a sensitive marker for hippocampal and extrahippocampal network function in transient global amnesia (TGA). Methods A group of 18 patients with TGA performed an established real-space navigation paradigm, requiring allo- and egocentric spatial orientation abilities, 3 days (postacute stage) and 3 months (follow-up) after symptom onset. Visual exploration behavior and navigation strategy were documented by a gaze-controlled, head-fixed camera. Allo- and egocentric spatial orientation performance was compared to that of 12 age-matched healthy controls. Navigation-induced brain activations were measured using [18F]-fluorodeoxyglucose-PET in a subgroup of 8 patients in the postacute stage and compared to those of the controls. Results In the postacute stage, the patients navigated worse and had higher error rates than controls in allocentric (p = 0.002), but not in egocentric, route planning (p = 0.30), despite complete recovery of verbal (p = 0.58) and figural memory (p = 0.11). Until follow-up, allocentric navigation deficits improved, but higher error rates and reduced use of shortcuts persisted (p < 0.0001). Patients still exhibited relatively more fixations of unique landmarks during follow-up (p = 0.05). PET measurements during the postacute stage showed increased navigation-induced brain activations in the right hippocampus, bilateral retrosplenial, parietal, and mesiofrontal cortices, and cerebellar dentate nucleus in patients compared to controls (p < 0.005). Conclusions Patients with TGA show selective and prolonged deficits of allocentric spatial orientation. Activations in right hippocampal and extrahippocampal hubs of the cerebral navigation network functionally substitute for the deficit in creating and updating the internal cognitive map in TGA.}, language = {en} } @misc{JurischkaDinterEfimovaetal., author = {Jurischka, Christoph and Dinter, Franziska and Efimova, Anastasia and Weiss, Romano and Schiebel, Juliane and Schulz, Christian and Fayziev, Bekzodjon and Schierack, Peter and Fischer, Thomas and R{\"o}diger, Stefan}, title = {An explorative study of polymers for 3D printing of bioanalytical test systems}, series = {Clinical Hemorheology and Microcirculation}, volume = {75}, journal = {Clinical Hemorheology and Microcirculation}, number = {1}, issn = {1875-8622}, doi = {10.3233/CH-190713}, pages = {57 -- 84}, abstract = {Background: The 3D printing is relevant as a manufacturing technology of functional models for forensic, pharmaceutical and bioanalytical applications such as drug delivery systems, sample preparation and point-of-care tests. Objective: Melting behavior and autofluorescence of materials are decisive for optimal printing and applicability of the product which are influenced by varying unknown additives. Methods: We have produced devices for bioanalytical applications from commercially available thermoplastic polymers using a melt-layer process. We characterized them by differential scanning calorimetry, fluorescence spectroscopy and functional assays (DNA capture assay, model for cell adhesion, bacterial adhesion and biofilm formation test). Results: From 14 tested colored, transparent and black materials we found only deep black acrylonitrile-butadiene-styrene (ABS) and some black polylactic acid (PLA) useable for fluorescence-based assays, with low autofluorescence only in the short-wave range of 300-400 nm. PLA was suitable for standard bioanalytical purposes due to a glass transition temperature of approximately 60°C, resistance to common laboratory chemicals and easy print processing. For temperature-critical methods, such as hybridization reactions up to 90°C, ABS was better suited. Conclusions: Autofluorescence was not a disadvantage per se but can also be used as a reference signal in assays. The rapid development of individual protocols for sample processing and analysis required the availability of a material with consistent quality over time. For fluorescence-based assays, the use of commercial standard materials did not seem to meet this requirement.}, language = {en} } @misc{KlichWilczekJanssenetal., author = {Klich, Maximilian and Wilczek, Sebastian and Janssen, Jesper Frederikus Jacobus and Brinkmann, Ralf Peter and Mussenbrock, Thomas and Trieschmann, Jan}, title = {Ion dynamics in capacitively coupled argon-xenon discharges}, series = {Plasma Sources Science and Technology}, volume = {30}, journal = {Plasma Sources Science and Technology}, number = {6}, issn = {1361-6595}, doi = {10.1088/1361-6595/ac02b0}, language = {en} } @misc{SchroederWerderRamaiolietal., author = {Schr{\"o}der, Lena and Werder, Dina von and Ramaioli, Cecilia and Wachtler, Thomas and Henningsen, Peter and Glasauer, Stefan and Lehnen, Nadine}, title = {Unstable Gaze in Functional Dizziness: A Contribution to Understanding the Pathophysiology of Functional Disorders}, series = {Frontiers in Neuroscience}, volume = {15}, journal = {Frontiers in Neuroscience}, issn = {1662-453X}, doi = {10.3389/fnins.2021.685590}, abstract = {Objective: We are still lacking a pathophysiological mechanism for functional disorders explaining the emergence and manifestation of characteristic, severely impairing bodily symptoms like chest pain or dizziness. A recent hypothesis based on the predictive coding theory of brain function suggests that in functional disorders, internal expectations do not match the actual sensory body states, leading to perceptual dysregulation and symptom perception. To test this hypothesis, we investigated the account of internal expectations and sensory input on gaze stabilization, a physiologically relevant parameter of gaze shifts, in functional dizziness. Methods: We assessed gaze stabilization in eight functional dizziness patients and 11 healthy controls during two distinct epochs of large gaze shifts: during a counter- rotation epoch (CR epoch), where the brain can use internal models, motor planning, and resulting internal expectations to achieve internally driven gaze stabilization; and during an oscillation epoch (OSC epoch), where, due to terminated motor planning, no movement expectations are present, and gaze is stabilized by sensory input alone. Results: Gaze stabilization differed between functional patients and healthy controls only when internal movement expectations were involved [F(1,17) = 14.63, p = 0.001, and partial η2 = 0.463]: functional dizziness patients showed reduced gaze stabilization during the CR (p = 0.036) but not OSC epoch (p = 0.26). Conclusion: While sensory-driven gaze stabilization is intact, there are marked, well- measurable deficits in internally-driven gaze stabilization in functional dizziness pointing at internal expectations that do not match actual body states. This experimental evidence supports the perceptual dysregulation hypothesis of functional disorders and is an important step toward understanding the underlying pathophysiology.}, language = {en} }