@misc{LehnenHeuserSağlametal., author = {Lehnen, Nadine and Heuser, Fabian and Sağlam, Murat and Schulz, Christian M. and Wagner, Klaus J. and Taki, Masakatsu and Kochs, Eberhard F. and Jahn, Klaus and Schneider, Erich}, title = {Opioid-induced nausea involves a vestibular problem preventable by head-rest}, series = {PLoS one}, volume = {10}, journal = {PLoS one}, number = {8}, issn = {1932-6203}, doi = {10.1371/journal.pone.0135263}, pages = {e0135263}, language = {en} } @misc{HeubergerSağlamToddetal., author = {Heuberger, Maria and Sağlam, Murat and Todd, Nicholas Sean and Jahn, Klaus and Schneider, Erich and Lehnen, Nadine}, title = {Covert anti-compensatory quick eye movements during head impulses}, series = {PLoS One}, volume = {9}, journal = {PLoS One}, number = {4}, issn = {1932-6203}, doi = {10.1371/journal.pone.0093086}, pages = {e93086}, language = {en} } @misc{HelmchenMachnerLehnenetal., author = {Helmchen, Christoph and Machner, Bj{\"o}rn and Lehnen, Nadine and Jahn, Klaus and Schneider, Erich}, title = {Current state of diagnostic management of acute vertigo: a survey of neurologists in Germany}, series = {Journal of Neurology}, volume = {261}, journal = {Journal of Neurology}, number = {8}, issn = {0340-5354}, doi = {10.1007/s00415-014-7405-9}, pages = {1638 -- 1640}, language = {en} } @misc{AgrawalSchubertMigliaccioetal., author = {Agrawal, Yuri and Schubert, Michael C. and Migliaccio, Americo A. and Zee, David S. and Schneider, Erich and Lehnen, Nadine}, title = {Evaluation of quantitative head impulse testing using search coils versus video-oculography in older individuals}, series = {Otology \& neurotology}, volume = {35}, journal = {Otology \& neurotology}, number = {2}, issn = {1537-4505}, doi = {10.1097/MAO.0b013e318287f343}, pages = {283 -- 288}, language = {en} } @misc{BartlLehnenKohlbecheretal., author = {Bartl, Klaus and Lehnen, Nadine and Kohlbecher, Stefan and Schneider, Erich}, title = {Head impulse testing using video-oculography}, series = {Annals of the New York Academy of Sciences}, volume = {1164}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, doi = {10.1111/j.1749-6632.2009.03850.x}, pages = {331 -- 333}, language = {en} } @misc{HeuserSchulzSağlametal., author = {Heuser, Fabian and Schulz, Christian and Sağlam, Murat and Ramaioli, Cecilia and Heuberger, Maria and Wagner, Klaus J. and Jahn, Klaus and Schneider, Erich and Brandt, Thomas and Glasauer, Stefan and Lehnen, Nadine}, title = {Preventing opioid-induced nausea and vomiting: Rest your head and close your eyes?}, series = {PloS one}, volume = {12}, journal = {PloS one}, number = {3}, issn = {1932-6203}, doi = {10.1371/journal.pone.0173925}, pages = {e0173925}, language = {en} } @misc{LehnenRamaioliHenningsenetal., author = {Lehnen, Nadine and Ramaioli, Cecilia and Henningsen, Peter and Glasauer, Stefan}, title = {An experimental litmus test of the emerging hypothesis that persistent physical symptoms can be explained as perceptual dysregulation}, series = {Journal of Psychosomatic Research}, volume = {114}, journal = {Journal of Psychosomatic Research}, issn = {1879-1360}, doi = {10.1016/j.jpsychores.2018.08.007}, pages = {15 -- 17}, language = {en} } @misc{LehnenKellererKnorretal., author = {Lehnen, Nadine and Kellerer, Silvy and Knorr, Alexander G. and Schlick, Cornelia and Jahn, Klaus and Schneider, Erich and Heuberger, Maria and Ramaioli, Cecilia}, title = {Head-Movement-Emphasized Rehabilitation in Bilateral Vestibulopathy}, series = {Frontiers in Neurology}, volume = {9}, journal = {Frontiers in Neurology}, issn = {1664-2295}, doi = {10.3389/fneur.2018.00562}, pages = {6}, language = {en} } @misc{HeubergerGrillSaglametal., author = {Heuberger, Maria and Grill, Eva and Saglam, Murat and Ramaioli, Cecilia and M{\"u}ller, Martin and Strobl, Ralf and Holle, Rolf and Peters, Annette and Schneider, Erich and Lehnen, Nadine}, title = {Usability of the Video Head Impulse Test: Lessons from the Population-Based Prospective KORA Study}, series = {Frontiers in Neurology}, volume = {9}, journal = {Frontiers in Neurology}, issn = {1664-2295}, doi = {10.3389/fneur.2018.00659}, pages = {7}, language = {en} } @misc{LehnenSchroederHenningsenetal., author = {Lehnen, Nadine and Schr{\"o}der, Lena and Henningsen, Peter and Glasauer, Stefan and Ramaioli, Cecilia}, title = {Deficient head motor control in functional dizziness: Experimental evidence of central sensory-motor dysfunction in persistent physical symptoms}, series = {Progress in Brain Research}, volume = {249}, journal = {Progress in Brain Research}, issn = {1875-7855}, doi = {10.1016/bs.pbr.2019.02.006}, pages = {385 -- 400}, abstract = {Understanding the mechanisms of symptoms that are insufficiently explained by organic dysfunction remains challenging. Recently, it has been proposed that such "functional symptoms" are based on erroneous sensory processing in the central nervous system (CNS), with internal expectations dominating sensory inputs. In a pilot study, we used a head motor control set-up to assess the interplay between sensory input and expectation on the example of patients with functional dizziness. Eight patients and 11 age-matched healthy controls performed large active eye-head gaze shifts towards visual targets in the natural situation and with the head moment of inertia 3.3-fold increased. The latter induces head oscillations and the expected sensory outcome of the movement, estimated in the CNS, does not match the actual sensory input. Head oscillations were assessed in patients and in healthy subjects and compared to prior results from patients with organic disease (vestibular loss and cerebellar ataxia). Head oscillations in patients with functional dizziness were different from those of healthy subjects (F(1,17) = 27.26, P < 0.001, partial η2 = 0.62), and similar to those of patients with cerebellar ataxia, and with vestibular loss (F(2,19) = 0.56, P = 0.58). Even in the natural, unweighted, condition, head oscillations were higher in functional dizziness patients than in healthy subjects (P = 0.001). Since an extensive work-up failed to demonstrate any explanatory peripheral vestibular, motor, or cerebellar organic dysfunction, these motor control deficits are a first indication of erroneous interplay between expectations and sensory input in the CNS that could account for persistent physical symptoms.}, language = {en} }