@misc{FrankFuegenschuhHertyetal., author = {Frank, Martin and F{\"u}genschuh, Armin and Herty, Michael and Schewe, Lars}, title = {The Coolest Path Problem}, series = {Networks \& Heterogeneous Media}, volume = {5}, journal = {Networks \& Heterogeneous Media}, number = {1}, issn = {1438-0064}, doi = {10.3934/nhm.2010.5.143}, pages = {143 -- 162}, language = {en} } @misc{FrankScheinerLurzetal., author = {Frank, Martin and Scheiner, Benedict and Lurz, Fabian and Weigel, Robert and K{\"o}lpin, Alexander}, title = {Low-Cost Transmitarray Antenna Designs in V-Band based on Unit-Cells with 1 Bit Phase Resolution}, series = {Frequenz}, volume = {73}, journal = {Frequenz}, number = {11/12}, issn = {2191-6349}, doi = {10.1515/freq-2019-0140}, pages = {355 -- 366}, language = {en} } @misc{TolksdorfKaiserPetretal., author = {Tolksdorf, Johann Friedrich and Kaiser, Knut and Petr, Libor and Herbig, Christoph and Koč{\´a}r, Petr and Heinrich, Susann and Wilke, Franziska D.H. and Theuerkauf, Martin and F{\"u}lling, Alexander and Schubert, Matthias and Schr{\"o}der, Frank and Křiv{\´a}nek, Roman and Schulz, Lars and Bonhage, Alexander and Hemker, Christiane}, title = {Past human impact in a mountain forest: geoarchaeology of a medieval glass production and charcoal hearth site in the Erzgebirge, Germany}, series = {Regional Environmental Change}, volume = {20}, journal = {Regional Environmental Change}, number = {3}, issn = {1436-378X}, doi = {10.1007/s10113-020-01638-1}, pages = {20}, language = {en} } @misc{FrankLurzWeigeletal., author = {Frank, Martin and Lurz, Fabian and Weigel, Robert and K{\"o}lpin, Alexander}, title = {Universal low-cost transmitarray antenna design at 61 GHz for beam steering with different feed antennas}, series = {WSA 2020 : 24th International ITG Workshop on Smart Antennas : February 18-20, 2020, Hamburg, Germany}, journal = {WSA 2020 : 24th International ITG Workshop on Smart Antennas : February 18-20, 2020, Hamburg, Germany}, publisher = {VDE VERLAG GmbH}, address = {Berlin ; Offenbach}, isbn = {978-380075200-3}, pages = {1 CD-ROM}, language = {en} } @misc{GerlingDrechslerKeuleretal., author = {Gerling, Charlotte and Drechsler, Martin and Keuler, Klaus and Leins, Johannes A. and Radtke, Kai and Schulz, Bj{\"o}rn and Sturm, Astrid and W{\"a}tzold, Frank}, title = {Modelling the cost-effective spatio-temporal allocation of conservation measures in agricultural landscapes facing}, publisher = {ZBW-Leibnitz Information Centre for Economics}, address = {Kiel ; Hamburg}, pages = {22}, abstract = {Beitr{\"a}ge zur Jahrestagung des Vereins f{\"u}r Socialpolitik 2021: Climate Economics}, language = {en} } @misc{GerlingDrechslerKeuleretal., author = {Gerling, Charlotte and Drechsler, Martin and Keuler, Klaus and Leins, Johannes A. and Radtke, Kai and Schulz, Bj{\"o}rn and Sturm, Astrid and W{\"a}tzold, Frank}, title = {Cost-effective conservation in the face of climate change: combining ecological-economic modelling and climate science for the cost-effective spatio-temporal allocation of conservation measures in agricultural landscapes}, series = {MPRA paper}, journal = {MPRA paper}, pages = {21}, language = {en} } @misc{DrechslerGerlingKeuleretal., author = {Drechsler, Martin and Gerling, Charlotte and Keuler, Klaus and Leins, Johannes A. and Sturm, Astrid and W{\"a}tzold, Frank}, title = {A quantitative approach for the design of robust and cost-effective conservation policies under uncertain climate change: The case of grasshopper conservation in Schleswig-Holstein, Germany}, series = {Journal of Environmental Management}, volume = {296}, journal = {Journal of Environmental Management}, issn = {1095-8630}, doi = {10.1016/j.jenvman.2021.113201}, pages = {7}, language = {en} } @misc{DrechslerWaetzoldGrimm, author = {Drechsler, Martin and W{\"a}tzold, Frank and Grimm, Volker}, title = {The hitchhiker's guide to generic ecological-economic modelling of land-use-based biodiversity conservation policies}, series = {Ecological Modelling}, volume = {465}, journal = {Ecological Modelling}, issn = {0304-3800}, doi = {10.1016/j.ecolmodel.2021.109861}, pages = {22}, language = {en} } @techreport{ThonickeRahnerArnethetal., author = {Thonicke, Kirsten and Rahner, Eva and Arneth, Almut and Bartkowski, Bartosz and Bonn, Aletta and D{\"o}hler, Christian and Finger, Robert and Freitag, Jens and Grosch, Rita and Grossart, Hans-Peter and Gr{\"u}tzmacher, Kim and Hartman Scholz, Amber and H{\"a}user, Christoph and Hickler, Thomas and H{\"o}lker, Franz and J{\"a}hnig, Sonja C. and Jeschke, Jonathan and Kassen, Rees and Kastner, Thomas and Kramer-Schadt, Stephanie and Krug, Cornelia and Lakner, Sebastian and Loft, Lasse and Matzdorf, Bettina and Meakins, Felicity and De Meester, Luc and Monaghan, Michael T. and M{\"u}ller, Daniel and Overmann, J{\"o}rg and Quaas, Martin and Radchuk, Viktoriia and Reyer, Christopher and Roos, Christian and Scholz, Imme and Schroer, Sibylle and Sioen, Giles Bruno and Sommer, Simone and Sommerwerk, Nike and Tockner, Klement and Turk, Zachary and Warner, Barbara and W{\"a}tzold, Frank and Wende, Wolfgang and Veenstra, Tonjes and Voort, Hein van de}, title = {10 Must-Knows aus der Biodiversit{\"a}tsforschung}, publisher = {Potsdam-Institut f{\"u}r Klimafolgenforschung e.V. (PIK)}, address = {Potsdam}, doi = {10.5281/zenodo.6257476}, pages = {58}, language = {de} } @misc{GerlingDrechslerKeuleretal., author = {Gerling, Charlotte and Drechsler, Martin and Keuler, Klaus and Sturm, Astrid and W{\"a}tzold, Frank}, title = {Time to consider the timing of conservation measures: designing cost-effective agri-environment schemes under climate change}, series = {MPRA paper}, journal = {MPRA paper}, pages = {38}, language = {en} } @misc{GerlingDrechslerKeuleretal., author = {Gerling, Charlotte and Drechsler, Martin and Keuler, Klaus and Leins, Johannes A. and Radtke, Kai and Schulz, Bj{\"o}rn and Sturm, Astrid and W{\"a}tzold, Frank}, title = {Climate-ecological-economic modelling for the cost-effective spatiotemporal allocation of conservation measures in cultural landscapes facing climate change}, series = {Q Open}, volume = {2}, journal = {Q Open}, number = {1}, issn = {2633-9048}, doi = {10.1093/qopen/qoac004}, pages = {1 -- 20}, language = {en} } @misc{BehrenTurekBarthelmesetal., author = {Behren, Sascha von and Turek, Maximilian and Barthelmes, Lukas and Scholta, Hanna and Hansen, Frank and Kagerbauer, Martin and Eisenmann, Christine}, title = {Decoding Urban Archetypes: Exploring Mobility-Related Homogeneity among Cities}, series = {Sustainability}, volume = {15}, journal = {Sustainability}, number = {19}, issn = {2071-1050}, doi = {10.3390/su151914231}, abstract = {To make cities more sustainable and livable and to achieve climate targets in transportation, cities around the globe must undergo sustainable transformations. However, disparities in initial conditions pose challenges when trying to implement these sustainable changes. Identifying these differences aids in the comprehension of future developments. In this study, we establish an international comparison by decoding the mobility-related characteristics of cities and determining urban archetypes. Using publicly accessible data, we analyze and classify 96 cities in different countries. Therefore, we utilize principal component analysis to simplify the data. The emerging components serve as input for segmentation. This approach yields nine unique urban archetypes, ranging from Well-Functioning and Ancient Hybrid Cities in Europe to Paratransit and Traffic-Saturated Cities in the southern hemisphere. Our results show that there is a significant advantage to using a multidimensional segmentation basis, which we identify in an extensive literature review. The result is a finer segmentation, which is especially clear for European cities that demonstrate four different clusters. We discuss that the effect of future restrictions on private car usage will vary widely between the urban archetypes.}, language = {en} } @techreport{BehrenTurekBarthelmesetal., author = {Behren, Sascha von and Turek, Maximilian and Barthelmes, Lukas and Scholta, Hanna and Hansen, Frank and Kagerbauer, Martin and Eisenmann, Christine}, title = {Urban Archetypes}, pages = {10}, abstract = {To make cities more sustainable and livable and to achieve climate targets in transportation, cities around the globe must undergo sustainable transformations. However, disparities in initial conditions pose challenges when trying to implement these sustainable changes. Identifying these differences aids in the comprehension of future developments. Urban archetypes represent a typification of cities in order to investigate mobility-related homogeneity between cities.}, language = {en} } @misc{GerlingSturmWaetzoldetal., author = {Gerling, Charlotte and Sturm, Astrid and W{\"a}tzold, Frank and Keuler, Klaus and Radtke, Kai and Drechsler, Martin and Leins, Johannes A.}, title = {{\"O}konomie der Klimaanpassung zum Schutz der biologischen Vielfalt ; Postervorstellung : BfN Statuskonferenz "Biodiversit{\"a}t und Klimawandel - Synergien erforschen" in Berlin, 7.12.2023}, doi = {10.13140/RG.2.2.16540.97923}, pages = {2}, language = {de} } @misc{GerlingDrechslerLeinsetal., author = {Gerling, Charlotte and Drechsler, Martin and Leins, Johannes A. and Sturm, Astrid and W{\"a}tzold, Frank}, title = {Cost-Effective Policy Instruments for Biodiversity Conservation Under Climate Change - the Need for Flexibility}, series = {SSRN eLibrary}, journal = {SSRN eLibrary}, issn = {1556-5068}, doi = {10.2139/ssrn.4617809}, pages = {1 -- 60}, language = {en} } @misc{GerlingDrechslerKeuleretal., author = {Gerling, Charlotte and Drechsler, Martin and Keuler, Klaus and Sturm, Astrid and W{\"a}tzold, Frank}, title = {Time to consider the timing of conservation measures: Designing cost-effective agri-environment schemes under climate change}, series = {Agricultural and Resource Economics Review}, volume = {52}, journal = {Agricultural and Resource Economics Review}, number = {2}, issn = {2372-2614}, doi = {10.1017/age.2023.4}, pages = {231 -- 249}, language = {en} } @misc{GerlingDrechslerKeuleretal., author = {Gerling, Charlotte and Drechsler, Martin and Keuler, Klaus and Leins, Johannes and Schulz, Bj{\"o}rn and Sturm, Astrid and W{\"a}tzold, Frank}, title = {Effektivit{\"a}t und Kosteneffizienz von Artenschutzmaßnahmen unter Klimawandel - das Beispiel der Sumpfschrecke (Stethophyma grossum) in Schleswig-Holstein}, series = {Natur und Landschaft}, volume = {100. Jahrgang 2025}, journal = {Natur und Landschaft}, number = {1}, isbn = {0028-0615-202501}, pages = {2 -- 8}, language = {de} } @misc{MartinNeubertLutteretal., author = {Martin, Frank and Neubert, Annemarie and Lutter, Anne-Helen and Scholka, Jenny and Hentschel, Erik and Richter, Heiko and Anderer, Ursula}, title = {MTS, WST-8, and ATP viability assays in 2D and 3D cultures: Comparison of methodologically different assays in primary human chondrocytes}, series = {Clinical Hemorheology and Microcirculation}, volume = {88}, journal = {Clinical Hemorheology and Microcirculation}, publisher = {IOS Press}, issn = {ISSN 1386-0291}, doi = {10.3233/CH-248101}, pages = {3 -- 19}, abstract = {BACKGROUND: Tissue engineering enables the production of three-dimensional microtissues which mimic naturally occurring conditions in special tissues. These 3D culture systems are particularly suitable for application in regenerative medicine or experimental pharmacology and toxicology. Therefore, it is important to analyse the cells in their 3D microenvironment with regard to viability and differentiation. Tetrazolium assays (WST-8 and MTS) are still the methods of choice for estimating the number of living, metabolically active cells, with WST-8 being cell-impermeable compared to MTS. In contrast to these methods, the ATP assay is an endpoint method based on the luciferase-induced reaction of ATP with luciferin after cell lysis. OBJECTIVE:We compared three methodologically different proliferation/toxicity assays (MTS, WST-8, ATP) in monolayer (2D) and 3D culture systems to improve the technically challenging determination of the number of viable cells. METHODS: Chondrocytes were isolated from human articular cartilage. Three different test systems (MTS, WST-8, ATP) were applied to monolayer cells (2D, varying cell numbers) and spheroids (3D, different sizes) in 96-well plates. The intracellular ATP concentration was determined by luciferase-induced reaction of ATP with luciferin using a luminometer. Formazan formation was measured spectrophotometrically after different incubation periods. Evaluation was performed by phase contrast microscopy (toxicity), correlation of cell count and ATP concentration or absorption signal (Gompertz function) and propidium iodide (PI) staining to proof the cell lysis of all cells in spheroids. RESULTS: In 2D culture, all three assays showed a good correlation between the number of seeded cells and the ATP concentration or absorption data, whereas the MTS-assay showed the lowest specificity. In 3D culture, the spheroid sizes were directly related to the number of cells seeded. The absorption data of the WST-8 and MTS assay correlated only for certain spheroid size ranges, whereas the MTS-assay showed again the lowest specificity. Only the measured intracellular ATP content showed a linear correlation with all spheroid sizes ranging from 100-1000 µm. The WST-8 assay revealed the second-best sensitivity which allows the measurement of spheroids larger than 240 µm. Phase contrast observation of monolayer cells showed toxic effects of MTS after 6 h incubation and no signs of toxicity of WST-8. Staining with propidium iodide showed complete lysis of all cells in a spheroid in the ATP assay. CONCLUSION: Among tetrazolium-based assays, WST-8 is preferable to MTS because of its non-toxicity and better sensitivity. When determining the number of viable cells in the 2D system, caution is advised when using the ATP assay because of its two-phase slope of the correlation graph concerning cell number and intracellular ATP. In 3D systems of human chondrocytes, the ATP-assay is superior to the other two test systems, as the correlation graph between cell number and intracellular ATP is biphasic. Since differentiation processes or other metabolic events can influence the results of proliferation and toxicity assays (determination of viable cells), this should be taken into account when using these test systems.}, language = {en} } @misc{GomezdeSantosGonzalezBenjumeaFernandezGarciaetal., author = {Gomez de Santos, Patricia and Gonz{\´a}lez-Benjumea, Alejandro and Fernandez-Garcia, Angela and Aranda, Carmen and Wu, Yinqi and But, Andrada and Molina-Espeja, Patricia and Mat{\´e}, Diana M. and Gonzalez-Perez, David and Zhang, Wuyuan and Kiebist, Jan and Scheibner, Katrin and Hofrichter, Martin and Swiderek, Katarzyna and Moliner, Vicent and Sanz-Aparicio, Julia and Hollmann, Frank and Guti{\´e}rrez, Ana and Alcalde, Miguel}, title = {Engineering a highly regioselective fungal peroxygenase for the synthesis of hydroxy fatty acids}, series = {Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker}, volume = {62}, journal = {Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-3773}, doi = {10.1002/anie.202217372}, pages = {1 -- 9}, abstract = {The hydroxylation of fatty acids is an appealing reaction in synthetic chemistry, although the lack of selective catalysts hampers its industrial implementation. In this study, we have engineered a highly regioselective fungal peroxygenase for the ω-1 hydroxylation of fatty acids with quenched stepwise over-oxidation. One single mutation near the Phe catalytic tripod narrowed the heme cavity, promoting a dramatic shift toward subterminal hydroxylation with a drop in the over-oxidation activity. While crystallographic soaking experiments and molecular dynamic simulations shed light on this unique oxidation pattern, the selective biocatalyst was produced by Pichia pastoris at 0.4 g L-1 in a fed-batch bioreactor and used in the preparative synthesis of 1.4 g of (ω-1) hydroxytetradecanoic acid with 95 \% regioselectivity and 83 \% ee for the S enantiomer.}, language = {en} } @misc{JiangKnaackMartinetal., author = {Jiang, Yuyao and Knaack, Marcus and Martin, Clas Aljoscha and Tost, Frank and Alimov, Artem and H{\"a}rtel, Sebastian and Gardill, Markus}, title = {A 120 GHz industrial radar sensor network for condition monitoring of a forging process}, series = {IEEE sensors journal}, journal = {IEEE sensors journal}, publisher = {IEEE}, address = {Piscataway, NJ}, issn = {1558-1748}, doi = {10.1109/JSEN.2025.3636060}, pages = {1 -- 10}, abstract = {Current trends in forging technology emphasize increased automation and a rising demand for high-precision components. Among the key factors influencing the forging quality are process parameters, which also serve as indispensable inputs for data-driven modeling. This necessitates the establishment of a stable and robust sensor network to enable high-quality process monitoring. This study investigates the implementation of a heterogeneous sensor network within an energy-bound forging press, integrating industrial 120 GHz radar sensors for comprehensive data collection. A complete radar signal processing chain is developed, encompassing signal acquisition, pre-processing, and state estimation of the press ram. The validation against conventional reference sensors confirms the reliability and accuracy of the radar-based measurements. The results demonstrate the feasibility of the radar employment in the complex forging environment.}, language = {en} }