@misc{TeufelBardinsSpiegeletal., author = {Teufel, Julian and Bardins, Stanislav and Spiegel, Rainer and Kremmyda, O. and Schneider, Erich and Strupp, Michael and Kalla, R.}, title = {Real time computerbased visual feedback improves visual acuity in downbeat nystagmus, a pilot study}, series = {Journal of NeuroEngineering and Rehabilitation}, volume = {13}, journal = {Journal of NeuroEngineering and Rehabilitation}, number = {1}, issn = {1743-0003}, language = {de} } @misc{FeilClaassenBrandinsetal., author = {Feil, Katharina and Claassen, Jens and Brandins, Stanislavs and Teufel, Julian and Krafczyk, Siegbert and Schneider, Erich}, title = {Effect of chlorzoxazone in patients with downbeat nystagmus: a pilot trial}, series = {Neurology}, volume = {81}, journal = {Neurology}, number = {13}, issn = {0028-3878}, doi = {10.1212/WNL.0b013e3182a55f6d}, pages = {1152 -- 1158}, language = {en} } @misc{ClaassenFeilBardinsetal., author = {Claassen, Jens and Feil, Katharina and Bardins, Stanislav and Teufel, Julian and Spiegel, Rainer and Kalla, Roger and Schneider, Erich}, title = {Dalfampridine in patients with downbeat nystagmus-an observational study}, series = {Journal of Neurology}, volume = {260}, journal = {Journal of Neurology}, number = {8}, issn = {0340-5354}, doi = {10.1007/s00415-013-6911-5}, pages = {1992 -- 1996}, language = {en} } @misc{SpiegelClaassenTeufeletal., author = {Spiegel, Rainer and Claassen, Jens and Teufel, Julian and Bardins, Stanislav and Schneider, Erich and Lehrer, Nicole and Jahn, Klaus and Anciaes da Silva, F{\´a}bio and Hahn, Ales and Farahmand, Parvis and Brandt, Thomas and Strupp, Michael and Kalla, Roger}, title = {Resting in darkness improves downbeat nystagmus: evidence from an observational study}, series = {Annals of the New York Academy of Sciences}, volume = {1375}, journal = {Annals of the New York Academy of Sciences}, number = {1}, issn = {1749-6632}, doi = {10.1111/nyas.13172}, pages = {66 -- 73}, abstract = {Resting in an upright position during daytime decreases downbeat nystagmus (DBN). When measured in brightness only, that is, without intermitting exposure to darkness, it does not make a significant difference whether patients have previously rested in brightness or in darkness. In real-world scenarios, people are often exposed to brightness and darkness intermittently. The aim of this study was to analyze whether resting in brightness or resting in darkness was associated with a lower post-resting DBN after intermitting exposures to brightness and darkness. Eight patients were recorded with three-dimensional video-oculography in brightness and darkness conditions, each following two 2-h resting intervals under either brightness or darkness resting conditions. The dependent variable was DBN intensity, measured in mean slow phase velocity. A repeated measures ANOVA with the factors measurement condition (brightness vs. darkness), resting condition (brightness vs. darkness), and time (after first vs. second resting interval) showed a significant effect for the factor resting condition, where previous resting in darkness was associated with a significantly lower DBN relative to previous resting in brightness (P < 0.01). The clinical relevance is to advise patients with DBN to rest in darkness.}, language = {en} }