@misc{FlorianSchrickerZenzetal., author = {Florian, Tobias and Schricker, Klaus and Zenz, Constantin and Otto, Andreas and Schmidt, Leander and Diegel, Christian and Friedmann, Hannes and Seibold, Marc and Hellwig, Peter and Fr{\"o}hlich, Fabian and Nagel, Falk and Kallage, Peter and Buttazzoni, Michele and Rack, Alexander and Requardt, Herwig and Chen, Yunhui and Bergmann, Jean Pierre}, title = {Combining in situ synchrotron X-ray imaging and multiphysics simulation to reveal pore formation dynamics in laser welding of copper}, series = {International Journal of Machine Tools and Manufacture}, volume = {204}, journal = {International Journal of Machine Tools and Manufacture}, publisher = {Elsevier BV}, issn = {0890-6955}, doi = {10.1016/j.ijmachtools.2024.104224}, pages = {1 -- 22}, abstract = {Laser beam welding has emerged as a powerful tool for manufacturing copper components in electrical vehicles, electronic devices or energy storage, owing to its rapid processing capabilities. Nonetheless, the material's high thermal conductivity and low absorption of infrared light can introduce process instabilities, resulting in defects such as pores. This study employs a hybrid approach that combines in situ synchrotron X-ray imaging with compressible multiphysics process simulation to elucidate pore-forming mechanisms during laser beam welding of copper. High-speed synchrotron X-ray imaging with an acquisition rate of 20,000 images/second facilitates the identification of relevant process regimes concerning pore formation during laser beam welding of copper with a wavelength of 1070 nm. Furthermore, in situ observations with high temporal and spatial resolution present a unique database for extensive validation of a multi-physics process simulation based on welding processes using different concentric intensity distributions. These validated simulation results enable thorough comprehension of process-related pore formation based on the interaction between keyhole, melt pool and resulting flow field. The findings show that pore formation is driven by four different mechanisms: bulging, spiking, upwelling waves at the keyhole rear wall and melt pool ejections. The synergy of high- speed synchrotron X-ray imaging and multi-physics modeling provides a fundamental understanding of the chronological sequence of events leading to process-related pore formation during laser beam welding of copper.}, language = {en} } @misc{HuberDreberHuberetal., author = {Huber, Christoph and Dreber, Anna and Huber, J{\"u}rgen and Johannesson, Magnus and Kirchler, Michael and Weitzel, Utz and Abell{\´a}n, Miguel and Adayeva, Xeniya and Ay, Fehime Ceren and Barron, Kai and Berry, Zachariah and B{\"o}nte, Werner and Br{\"u}tt, Katharina and Bulutay, Muhammed and Campos-Mercade, Pol and Cardella, Eric and Claassen, Maria Almudena and Cornelissen, Gert and Dawson, Ian G. J. and Delnoij, Joyce and Demiral, Elif E. and Dimant, Eugen and Doerflinger, Johannes Theodor and Dold, Malte and Emery, C{\´e}cile and Fiala, Lenka and Fiedler, Susann and Freddi, Eleonora and Fries, Tilman and Gasiorowska, Agata and Glogowsky, Ulrich and Gorny, Paul Matthias and Gretton, Jeremy David and Grohmann, Antonia and Hafenbr{\"a}dl, Sebastian and Handgraaf, Michel and Hanoch, Yaniv and Hart, Einav and Hennig, Max and Hudja, Stanton and H{\"u}tter, Mandy and Hyndman, Kyle and Ioannidis, Konstantinos and Isler, Ozan and Jeworrek, Sabrina and Jolles, Daniel and Juanchich, Marie and Raghabendra, Pratap K.C. and Khadjavi, Menusch and Kugler, Tamar and Li, Shuwen and Lucas, Brian and Mak, Vincent and Mechtel, Mario and Merkle, Christoph and Meyers, Ethan Andrew and Mollerstrom, Johanna and Nesterov, Alexander and Neyse, Levent and Nieken, Petra and Nussberger, Anne-Marie and Palumbo, Helena and Peters, Kim and Pirrone, Angelo and Qin, Xiangdong and Rahal, Rima Maria and Rau, Holger and Rincke, Johannes and Ronzani, Piero and Roth, Yefim and Saral, Ali Seyhun and Schmitz, Jan and Schneider, Florian and Schram, Arthur and Schudy, Simeon and Schweitzer, Maurice E. and Schwieren, Christiane and Scopelliti, Irene and Sirota, Miroslav and Sonnemans, Joep and Soraperra, Ivan and Spantig, Lisa and Steimanis, Ivo and Steinmetz, Janina and Suetens, Sigrid and Theodoropoulou, Andriana and Urbig, Diemo and Vorlaufer, Tobias and Waibel, Joschka and Woods, Daniel and Yakobi, Ofir and Yilmaz, Onurcan and Zaleskiewicz, Tomasz and Zeisberger, Stefan and Holzmeister, Felix}, title = {Competition and moral behavior: A meta-analysis of forty-five crowd-sourced experimental designs}, series = {Proceedings of the National Academy of Sciences}, volume = {120}, journal = {Proceedings of the National Academy of Sciences}, number = {23}, issn = {0027-8424}, doi = {10.1073/pnas.2215572120}, abstract = {Does competition affect moral behavior? This fundamental question has been debated among leading scholars for centuries, and more recently, it has been tested in experimental studies yielding a body of rather inconclusive empirical evidence. A potential source of ambivalent empirical results on the same hypothesis is design heterogeneity—variation in true effect sizes across various reasonable experimental research protocols. To provide further evidence on whether competition affects moral behavior and to examine whether the generalizability of a single experimental study is jeopardized by design heterogeneity, we invited independent research teams to contribute experimental designs to a crowd-sourced project. In a large-scale online data collection, 18,123 experimental participants were randomly allocated to 45 randomly selected experimental designs out of 95 submitted designs. We find a small adverse effect of competition on moral behavior in a meta-analysis of the pooled data. The crowd-sourced design of our study allows for a clean identification and estimation of the variation in effect sizes above and beyond what could be expected due to sampling variance. We find substantial design heterogeneity—estimated to be about 1.6 times as large as the average standard error of effect size estimates of the 45 research designs—indicating that the informativeness and generalizability of results based on a single experimental design are limited. Drawing strong conclusions about the underlying hypotheses in the presence of substantive design heterogeneity requires moving toward much larger data collections on various experimental designs testing the same hypothesis.}, language = {en} } @misc{GriesshammerMalessaLuetal., author = {Grießhammer, Stefan G. and Malessa, Anke and Lu, Hui and Yip, Julia and Leuschner, Julie and Christgau, Florian and Albrecht, Nils C. and Oesten, Marie and Tran, Thanh Truc and Richer, Robert and Heckel, Maria and Eskofier, Bjoern M. and Koelpin, Alexander and Steigleder, Tobias and Ostgathe, Christoph}, title = {Contactless radar-based heart rate estimation in palliative care : a feasibility study and possible use in symptom management}, series = {BMC palliative care}, volume = {23}, journal = {BMC palliative care}, number = {1}, publisher = {BioMed Central}, address = {London}, issn = {1472-684X}, doi = {10.1186/s12904-024-01592-3}, pages = {1 -- 14}, abstract = {Background Heart rate (HR) monitoring is a medical standard to provide information about a patient's health status. In palliative care, relationship and social engagement are crucial therapeutic concepts. For fear of disrupting communication, social contact, and care, continuous HR monitoring is underutilised despite its potential to inform on symptom burden and therapeutic effects. This study investigates radar-based HR monitoring as an innovative and burden-free approach for palliative care patients, compares its accuracy with conventional ECG methods, and shows potential for therapeutic guidance. Methods A single-centre, comparative clinical trial was conducted with palliative care patients at the ward of the Department of Palliative Medicine of the University Hospital of Erlangen. The HR measurements obtained with radar were compared with Holter ECG (study arm I, overnight) and Task Force ® Monitor (TFM)-based ECG validation recordings (study arm II, one hour). In addition, long-term radar measurements without validation were analysed in comparison with clinical health records (study arm III). Results Both validation methods showed correlation by scatter plot, modified Bland-Altman plot, and equivalence testing. N  = 34 patients participated in study arm I. HR of 4,079 five-minute intervals was analysed. Radar measurements and ECG showed high agreement: difference of HRs was within 5 bpm in 3780 of 4079 (92.67\%) and within ±13.4 bpm ( 1.96 times the SD of the mean) in 3979 (97.55\%) intervals, respectively. In study arm II, n  = 19 patients participated. 57,048 heart beats were analysed. The HR difference was within 5 bpm for 53,583 out of 57,048 beats (93.93\%) and within 8.2 bpm ( ± 1.96 times the SD of the mean) in 55,439 beats (97.18\%), respectively. Arm III showed HR changes extracted from radar data in correlation with symptoms and treatment. Conclusion Radar-based HR monitoring shows a high agreement in comparison with ECG-based HR monitoring and thus offers an option for continuous and above all burden-free HR assessment, with the potential for use in symptom management in palliative care, among others. Further research and technological advancements are still necessary to fully realize this innovative approach in enhancing palliative care practices.}, language = {en} }