@misc{SchulzSkrzypczakSchneideretal., author = {Schulz, Christian M. and Skrzypczak, M. and Schneider, Erich and Hapfelmeier, Alexander and Martin, J. and Kochs, Eberhard F. and Schneider, G.}, title = {Assessment of subjective workload in an anaesthesia simulator environment: reliability and validity}, series = {European Journal of Anaesthesiology}, volume = {28}, journal = {European Journal of Anaesthesiology}, number = {7}, issn = {0265-0215}, pages = {502 -- 505}, language = {en} } @incollection{KohlbecherBartlSchneideretal., author = {Kohlbecher, Stefan and Bartl, Klaus and Schneider, Erich and Blume, J{\"u}rgen and Bannat, Alexander and Sosnowski, Stefan and K{\"u}hnlenz, Kolja and Rigoll, Gerhard and Wallhoff, Frank}, title = {Test environment for studying the human-likeness of robotic eye movements}, series = {Biologically Inspired Robotics}, booktitle = {Biologically Inspired Robotics}, editor = {Liu, Yunhui and Sun, Dong}, publisher = {CRC Press}, address = {Boca Raton, Fl}, isbn = {1-4398-5488-2}, pages = {309}, language = {en} } @misc{SchulzSchneiderKohlbecheretal., author = {Schulz, Christian M. and Schneider, Erich and Kohlbecher, Stefan and Hapfelmeier, Alexander and Heuser, Fabian}, title = {The influence of anaesthetists' experience on workload, performance and visual attention during simulated critical incidents}, series = {Journal of Clinical Monitoring and Computing}, volume = {28}, journal = {Journal of Clinical Monitoring and Computing}, number = {5}, issn = {1387-1307}, doi = {10.1007/s10877-013-9443-8}, pages = {475 -- 480}, language = {en} } @misc{RamaioliColagiorgioSağlametal., author = {Ramaioli, Cecilia and Colagiorgio, Paolo and Sağlam, Murat and Heuser, Fabian and Schneider, Erich}, title = {The effect of vestibulo-ocular reflex deficits and covert saccades on dynamic vision in opioid-induced vestibular}, series = {PLoS One}, volume = {9}, journal = {PLoS One}, number = {10}, issn = {1932-6203}, doi = {10.1371/journal.pone.0110322}, pages = {e110322}, language = {en} } @misc{LehnenHeuserSağlametal., author = {Lehnen, Nadine and Heuser, Fabian and Sağlam, Murat and Schulz, Christian M. and Wagner, Klaus J. and Taki, Masakatsu and Kochs, Eberhard F. and Jahn, Klaus and Schneider, Erich}, title = {Opioid-induced nausea involves a vestibular problem preventable by head-rest}, series = {PLoS one}, volume = {10}, journal = {PLoS one}, number = {8}, issn = {1932-6203}, doi = {10.1371/journal.pone.0135263}, pages = {e0135263}, language = {en} } @misc{KuglerHartKohlbecheretal., author = {Kugler, G{\"u}nter and Hart, Bernhard Marius 't and Kohlbecher, Stefan and Einh{\"a}user, Wolfgang and Schneider, Erich}, title = {Gaze in visual search is guided more efficiently by positive cues than by negative cues}, series = {PLoS one}, volume = {10}, journal = {PLoS one}, number = {12}, issn = {1932-6203}, doi = {10.1371/journal.pone.0145910}, pages = {e0145910}, language = {en} } @misc{KuglerHartKohlbecheretal., author = {Kugler, G{\"u}nter and Hart, Bernhard Marius 't and Kohlbecher, Stefan and Bartl, Klaus and Schumann, Frank and Einh{\"a}user, Wolfgang and Schneider, Erich}, title = {Visual search in the real world: Color vision deficiency affects peripheral guidance, but leaves foveal verification largely unaffected}, series = {Frontiers in human neuroscience}, volume = {9}, journal = {Frontiers in human neuroscience}, issn = {1662-5161}, doi = {10.3389/fnhum.2015.00680}, pages = {680}, language = {en} } @misc{LuisZhuCostaetal., author = {Luis, Leonel and Zhu, Hong and Costa, Jo{\~a}o and Valls-Sol{\´e}, Josep and Brandt, Thomas and Zhou, Wu and Schneider, Erich}, title = {Reply to the commentary on luis et al. "spontaneous plugging of the horizontal semicircular canal with reversible canal dysfunction and recovery of vestibular evoked myogenic potentials}, series = {Otology \& Neurotology}, volume = {35}, journal = {Otology \& Neurotology}, number = {2}, issn = {1531-7129}, pages = {379 -- 383}, language = {en} } @misc{KuglerHuppertSchneideretal., author = {Kugler, G{\"u}nter and Huppert, Doreen and Schneider, Erich and Brandt, Thomas}, title = {Fear of heights freezes gaze to the horizon}, series = {Journal of Vestibular Research}, volume = {24}, journal = {Journal of Vestibular Research}, number = {5-6}, issn = {0957-4271}, doi = {10.3233/VES-140529}, pages = {433 -- 441}, language = {en} } @misc{KuglerHuppertEckletal., author = {Kugler, G{\"u}nter and Huppert, Doreen and Eckl, Maria and Schneider, Erich and Brandt, Thomas}, title = {Visual exploration during locomotion limited by fear of heights}, series = {PLoS One}, volume = {9}, journal = {PLoS One}, number = {8}, issn = {1932-6203}, doi = {10.1371/journal.pone.0105906}, pages = {e105906}, language = {en} } @misc{JerinBartlSchneideretal., author = {Jerin, Claudia and Bartl, Klaus and Schneider, Erich and G{\"u}rkov, Robert}, title = {Enhancing the reproducibility of ocular vestibular evoked myogenic potentials by use of a visual target originating from a head-mounted laser}, series = {European Archives of Oto-Rhino-Laryngology}, volume = {272}, journal = {European Archives of Oto-Rhino-Laryngology}, number = {10}, issn = {0937-4477}, doi = {10.1007/s00405-014-3271-4}, pages = {2737 -- 2740}, language = {en} } @misc{HeubergerSağlamToddetal., author = {Heuberger, Maria and Sağlam, Murat and Todd, Nicholas Sean and Jahn, Klaus and Schneider, Erich and Lehnen, Nadine}, title = {Covert anti-compensatory quick eye movements during head impulses}, series = {PLoS One}, volume = {9}, journal = {PLoS One}, number = {4}, issn = {1932-6203}, doi = {10.1371/journal.pone.0093086}, pages = {e93086}, language = {en} } @misc{HelmchenMachnerLehnenetal., author = {Helmchen, Christoph and Machner, Bj{\"o}rn and Lehnen, Nadine and Jahn, Klaus and Schneider, Erich}, title = {Current state of diagnostic management of acute vertigo: a survey of neurologists in Germany}, series = {Journal of Neurology}, volume = {261}, journal = {Journal of Neurology}, number = {8}, issn = {0340-5354}, doi = {10.1007/s00415-014-7405-9}, pages = {1638 -- 1640}, language = {en} } @misc{AgrawalSchubertMigliaccioetal., author = {Agrawal, Yuri and Schubert, Michael C. and Migliaccio, Americo A. and Zee, David S. and Schneider, Erich and Lehnen, Nadine}, title = {Evaluation of quantitative head impulse testing using search coils versus video-oculography in older individuals}, series = {Otology \& neurotology}, volume = {35}, journal = {Otology \& neurotology}, number = {2}, issn = {1537-4505}, doi = {10.1097/MAO.0b013e318287f343}, pages = {283 -- 288}, language = {en} } @misc{SrulijesMackKlenketal., author = {Srulijes, Karin and Mack, David J. and Klenk, Jochen and Ihlen, Espen A. F. and Schwenk, Michael and Lindemann, Ulrich and Schneider, Erich}, title = {Association between vestibulo-ocular reflex suppression, balance, gait, and fall risk in ageing and neurodegenerative disease: protocol of a one-year prospective follow-up study.}, series = {BMC Neurol}, volume = {15}, journal = {BMC Neurol}, issn = {1471-2377}, doi = {10.1186/s12883-015-0447-5}, pages = {192}, language = {en} } @misc{SchneiderVillgrattnerVockerothetal., author = {Schneider, Erich and Villgrattner, Thomas and Vockeroth, Johannes and Bartl, Klaus and Kohlbecher, Stefan and Bardins, Stanislav and Ulbrich, Heinz and Brandt, Thomas}, title = {Eyeseecam: an eye movement-driven head camera for the examination of natural visual exploration}, series = {Annals of the New York Academy of Sciences}, volume = {1164}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, doi = {10.1111/j.1749-6632.2009.03858.x}, pages = {461 -- 467}, language = {en} } @misc{SchneiderBartlGlasauer, author = {Schneider, Erich and Bartl, Klaus and Glasauer, Stefan}, title = {Galvanic vestibular stimulation combines with earth-horizontal rotation in roll to induce the illusion of translation.}, series = {Annals of the New York Academy of Sciences}, volume = {1164}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, doi = {10.1111/j.1749-6632.2008.03732.x}, pages = {116 -- 118}, language = {en} } @misc{HartVockerothSchumannetal., author = {Hart, Bernhard Marius 't and Vockeroth, Johannes and Schumann, Frank and Bartl, Klaus and Schneider, Erich and K{\"o}nig, Peter and Einh{\"a}user, Wolfgang}, title = {Gaze allocation in natural stimuli: Comparing free exploration to head-fixed viewing conditions.}, series = {Visual Cognition}, volume = {17}, journal = {Visual Cognition}, number = {6-7}, issn = {1350-6285}, doi = {10.1080/13506280902812304}, pages = {1132 -- 1158}, language = {en} } @misc{SpiegelKallaClaassenetal., author = {Spiegel, Rainer and Kalla, Roger and Claassen, Jens and Bardins, Stanislav and Anci{\~a}es da Silva, F{\´a}bio and Farahmand, Parvis and Hahn, Ales and Schneider, Erich}, title = {Aminopyridine treatment in a patient with bilateral vestibular failure and cryptogenic downbeat nystagmus}, series = {Journal of Neuro-Ophthalmology}, volume = {32}, journal = {Journal of Neuro-Ophthalmology}, number = {2}, issn = {1536-5166}, pages = {190}, language = {en} } @misc{VillgrattnerSchneiderAnderschetal., author = {Villgrattner, Thomas and Schneider, Erich and Andersch, Philipp and Ulbrich, Heinz}, title = {Compact high dynamic 3 DoF camera orientation system: Development and control}, series = {Journal of System Design and Dynamics}, volume = {5}, journal = {Journal of System Design and Dynamics}, number = {5}, issn = {1881-3046}, doi = {10.1299/jsdd.5.819}, pages = {819 -- 828}, language = {en} } @misc{KohlbecherSchneider, author = {Kohlbecher, Stefan and Schneider, Erich}, title = {On-line classification and prediction of eye movements by multiplemodel kalman filtering}, series = {Annals of the New York Academy of Sciences}, volume = {1164}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, doi = {10.1111/j.1749-6632.2009.03776.x}, pages = {400 -- 402}, language = {en} } @misc{EinhaeuserMoellerSchumannetal., author = {Einh{\"a}user, Wolfgang and Moeller, Gudrun U. and Schumann, Frank and Conradt, J{\"o}rg and Vockeroth, Johannes and Bartl, Klaus and Schneider, Erich and K{\"o}nig, Peter}, title = {Eye-head coordination during free exploration in human and cat.}, series = {Annals of the New York Academy of Sciences}, volume = {1164}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, doi = {10.1111/j.1749-6632.2008.03709.x}, pages = {353 -- 366}, language = {en} } @misc{BartlLehnenKohlbecheretal., author = {Bartl, Klaus and Lehnen, Nadine and Kohlbecher, Stefan and Schneider, Erich}, title = {Head impulse testing using video-oculography}, series = {Annals of the New York Academy of Sciences}, volume = {1164}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, doi = {10.1111/j.1749-6632.2009.03850.x}, pages = {331 -- 333}, language = {en} } @misc{SchneiderJahnDieterichetal., author = {Schneider, Erich and Jahn, Klaus and Dieterich, Marianne and Brandt, Thomas and Strupp, Michael}, title = {Gait deviations induced by visual stimulation in roll}, series = {Experimental Brain Research}, volume = {185}, journal = {Experimental Brain Research}, number = {1}, issn = {0014-4819}, doi = {10.1007/s00221-007-1134-6}, pages = {21 -- 26}, language = {en} } @misc{SchumannEinhaeuserVockerothetal., author = {Schumann, Frank and Einh{\"a}user, Wolfgang and Vockeroth, Johannes and Bartl, Klaus and Schneider, Erich and K{\"o}nig, Peter}, title = {Salient features in gaze-aligned recordings of human visual input during free exploration of natural environments}, series = {Journal of Vision}, volume = {8}, journal = {Journal of Vision}, number = {14}, issn = {1534-7362}, doi = {10.1167/8.14.12}, pages = {1210 -- 1217}, language = {en} } @misc{LuisCostaVazGarciaetal., author = {Luis, Leonel and Costa, Jo{\~a}o and Vaz Garcia, Fernando and Valls-Sol{\´e}, Josep and Brandt, Thomas and Schneider, Erich}, title = {Spontaneous plugging of the horizontal semicircular canal with reversible canal dysfunction and recovery of vestibular evoked myogenic potentials}, series = {Otology \& neurotology}, volume = {34}, journal = {Otology \& neurotology}, number = {4}, issn = {1537-4505}, pages = {743 -- 747}, language = {en} } @misc{ClaassenSpiegelKallaetal., author = {Claassen, Jens and Spiegel, Rainer and Kalla, Roger and Faldon, Mary and Kennard, Christopher and Schneider, Erich}, title = {A randomised double-blind, cross-over trial of 4-aminopyridine for downbeat nystagmus-effects on slowphase eye velocity, postural stability, locomotion and symptoms}, series = {Journal of neurology, neurosurgery, and psychiatry}, volume = {84}, journal = {Journal of neurology, neurosurgery, and psychiatry}, number = {12}, issn = {0022-3050}, doi = {10.1136/jnnp-2012-304736}, pages = {1392 -- 1399}, language = {en} } @misc{ClaassenFeilBardinsetal., author = {Claassen, Jens and Feil, Katharina and Bardins, Stanislav and Teufel, Julian and Spiegel, Rainer and Kalla, Roger and Schneider, Erich}, title = {Dalfampridine in patients with downbeat nystagmus-an observational study}, series = {Journal of Neurology}, volume = {260}, journal = {Journal of Neurology}, number = {8}, issn = {0340-5354}, doi = {10.1007/s00415-013-6911-5}, pages = {1992 -- 1996}, language = {en} } @misc{BrandtGlasauerSchneider, author = {Brandt, Thomas and Glasauer, Stefan and Schneider, Erich}, title = {A third eye for the surgeon}, series = {Journal of neurology, neurosurgery, and psychiatry}, volume = {77}, journal = {Journal of neurology, neurosurgery, and psychiatry}, number = {2}, issn = {0022-3050}, doi = {10.1136/jnnp.2005.073734}, pages = {278}, language = {en} } @misc{JahnNaesslSchneideretal., author = {Jahn, Klaus and Naeßl, Andrea and Schneider, Erich and Strupp, Michael and Brandt, Thomas and Dieterich, Marianne}, title = {Inverse u-shaped curve for age dependency of torsional eye movement responses to galvanic vestibular stimulation}, series = {Brain}, volume = {126}, journal = {Brain}, number = {7}, issn = {1460-2156}, doi = {10.1093/brain/awg163}, pages = {1579 -- 1589}, language = {en} } @misc{JahnNaesslStruppetal., author = {Jahn, Klaus and Naeßl, Andrea and Strupp, Michael and Schneider, Erich and Brandt, Thomas and Dieterich, Marianne}, title = {Torsional eye movement responses to monaural and binaural galvanic vestibular stimulation: side-to-side asymmetries.}, series = {Annals of the New York Academy of Sciences}, volume = {1004}, journal = {Annals of the New York Academy of Sciences}, issn = {0077-8923}, doi = {10.1111/j.1749-6632.2003.tb00265.x}, pages = {485 -- 489}, language = {en} } @misc{JahnStruppSchneideretal., author = {Jahn, Klaus and Strupp, Michael and Schneider, Erich and Dieterich, Marianne and Brandt, Thomas}, title = {Visually induced gait deviations during different locomotion speeds}, series = {Experimental Brain Research}, volume = {141}, journal = {Experimental Brain Research}, number = {3}, issn = {0014-4819}, doi = {10.1007/s002210100884}, pages = {370 -- 374}, language = {en} } @misc{SchneiderGlasauerDieterich, author = {Schneider, Erich and Glasauer, Stefan and Dieterich, Marianne}, title = {Central processing of human ocular torsion analyzed by galvanic vestibular stimulation}, series = {Neuroreport}, volume = {11}, journal = {Neuroreport}, number = {7}, issn = {0959-4965}, pages = {1559 -- 1563}, language = {en} } @misc{JahnStruppSchneideretal., author = {Jahn, Klaus and Strupp, Michael and Schneider, Erich and Dieterich, Marianne and Brandt, Thomas}, title = {Differential effects of vestibular stimulation on walking and running}, series = {Neuroreport}, volume = {11}, journal = {Neuroreport}, number = {8}, issn = {1473-558X}, pages = {1745 -- 1748}, language = {en} } @misc{StephanDeutschlaenderNolteetal., author = {Stephan, Thomas and Deutschl{\"a}nder, Angela and Nolte, Annina and Schneider, Erich and Wiesmann, Martin and Brandt, Thomas and Dieterich, Marianne}, title = {Functional mri of galvanic vestibular stimulation with alternating currents at different frequencies}, series = {Neuroimage}, volume = {26}, journal = {Neuroimage}, number = {3}, issn = {1053-8119}, doi = {10.1016/j.neuroimage.2005.02.049}, pages = {721 -- 732}, language = {en} } @misc{GlasauerSchneiderJahnetal., author = {Glasauer, Stefan and Schneider, Erich and Jahn, Klaus and Strupp, Michael}, title = {How the eyes move the body}, series = {Neurology}, volume = {65}, journal = {Neurology}, number = {8}, issn = {0028-3878}, doi = {10.1212/01.wnl.0000175132.01370.fc}, pages = {1291 -- 1293}, language = {en} } @misc{BartlSchneiderGlasauer, author = {Bartl, Klaus and Schneider, Erich and Glasauer, Stefan}, title = {Dependence of the torsional vestibulo-ocular reflex on the direction of gravity}, series = {Annals of the New York Academy of Sciences}, volume = {1039}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, doi = {10.1196/annals.1325.043}, pages = {455 -- 458}, language = {en} } @inproceedings{StollKohlbecherMarxetal., author = {Stoll, Josef and Kohlbecher, Stefan and Marx, Svenja and Schneider, Erich and Einh{\"a}user, Wolfgang}, title = {Mobile three dimensional gaze tracking}, series = {Medicine meets virtual reality 18}, booktitle = {Medicine meets virtual reality 18}, editor = {Westwood, James D.}, publisher = {IOS Press}, address = {Amsterdam}, isbn = {978-1-60750-705-5}, pages = {616 -- 622}, language = {en} } @inproceedings{KohlbecherBartlBardinsetal., author = {Kohlbecher, Stefan and Bartl, Klaus and Bardins, Stanislav and Schneider, Erich}, title = {Low-latency combined eye and head tracking system for teleoperating a robotic head in real-time}, series = {Proceedings of the 2010 Symposium on EyeTracking Research \& Applications}, booktitle = {Proceedings of the 2010 Symposium on EyeTracking Research \& Applications}, publisher = {ACM Press}, address = {New York}, isbn = {978-1-60558-994-7}, doi = {10.1145/1743666.1743695}, pages = {117 -- 120}, language = {en} } @inproceedings{VockerothBartlPfanzeltetal., author = {Vockeroth, Johannes and Bartl, Klaus and Pfanzelt, Sandra and Schneider, Erich}, title = {Medical documentation using a gaze-driven camera}, series = {Medicine meets virtual reality 17}, booktitle = {Medicine meets virtual reality 17}, editor = {Westwood, James D.}, publisher = {IOS Press}, address = {Amsterdam}, isbn = {978-160-750-402-3}, pages = {413 -- 416}, language = {en} } @inproceedings{SchneiderKohlbecherBartletal., author = {Schneider, Erich and Kohlbecher, Stefan and Bartl, Klaus and Wallhoff, Frank and Brandt, Thomas}, title = {Experimental platform for wizard-of-oz evaluations of biomimetic active vision in robots}, series = {IEEE International Conference on Robotics and Biomimetics (ROBIO), 2009, 19 - 23 Dec. 2009, Guilin, China}, booktitle = {IEEE International Conference on Robotics and Biomimetics (ROBIO), 2009, 19 - 23 Dec. 2009, Guilin, China}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4244-4774-9}, pages = {1484 -- 1489}, language = {en} } @misc{SchneiderGlasauerBrandtetal., author = {Schneider, Erich and Glasauer, Stefan and Brandt, Thomas and Dieterich, Marianne}, title = {Nonlinear nystagmus processing causes torsional vor nonlinearity}, series = {Annals of the New York Academy of Sciences}, volume = {1004}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, pages = {500 -- 505}, language = {en} } @misc{StruppGlasauerJahnetal., author = {Strupp, Michael and Glasauer, Stefan and Jahn, Klaus and Schneider, Erich and Krafczyk, Siegbert and Brandt, Thomas}, title = {Eye movements and balance}, series = {Annals of the New York Academy of Sciences}, volume = {1004}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, pages = {352 -- 358}, language = {en} } @misc{StruppGlasauerSchneideretal., author = {Strupp, Michael and Glasauer, Stefan and Schneider, Erich and Eggert, Thomas and Glaser, Miriam}, title = {Anterior canal failure: ocular torsion without perceptual tilt due to preserved otolith function}, series = {Journal of Neurology Neurosurgery \& Psychiatry}, volume = {74}, journal = {Journal of Neurology Neurosurgery \& Psychiatry}, number = {9}, issn = {1468-330X}, doi = {10.1136/jnnp.74.9.1336}, pages = {1336 -- 1338}, language = {en} } @misc{HeuserSchulzSağlametal., author = {Heuser, Fabian and Schulz, Christian and Sağlam, Murat and Ramaioli, Cecilia and Heuberger, Maria and Wagner, Klaus J. and Jahn, Klaus and Schneider, Erich and Brandt, Thomas and Glasauer, Stefan and Lehnen, Nadine}, title = {Preventing opioid-induced nausea and vomiting: Rest your head and close your eyes?}, series = {PloS one}, volume = {12}, journal = {PloS one}, number = {3}, issn = {1932-6203}, doi = {10.1371/journal.pone.0173925}, pages = {e0173925}, language = {en} } @misc{LehnenKellererKnorretal., author = {Lehnen, Nadine and Kellerer, Silvy and Knorr, Alexander G. and Schlick, Cornelia and Jahn, Klaus and Schneider, Erich and Heuberger, Maria and Ramaioli, Cecilia}, title = {Head-Movement-Emphasized Rehabilitation in Bilateral Vestibulopathy}, series = {Frontiers in Neurology}, volume = {9}, journal = {Frontiers in Neurology}, issn = {1664-2295}, doi = {10.3389/fneur.2018.00562}, pages = {6}, language = {en} } @misc{HeubergerGrillSaglametal., author = {Heuberger, Maria and Grill, Eva and Saglam, Murat and Ramaioli, Cecilia and M{\"u}ller, Martin and Strobl, Ralf and Holle, Rolf and Peters, Annette and Schneider, Erich and Lehnen, Nadine}, title = {Usability of the Video Head Impulse Test: Lessons from the Population-Based Prospective KORA Study}, series = {Frontiers in Neurology}, volume = {9}, journal = {Frontiers in Neurology}, issn = {1664-2295}, doi = {10.3389/fneur.2018.00659}, pages = {7}, language = {en} } @misc{SchoeberlIrvingPradhanetal., author = {Sch{\"o}berl, Florian and Irving, Stephanie and Pradhan, Cauchy and Bardins, Stanislav and Trapp, Christoph and Schneider, Erich and Kugler, G{\"u}nter and Bartenstein, Peter and Dietrich, Marianne and Brandt, Thomas and Zwergal, Andreas}, title = {Prolonged allocentric navigation deficits indicate hippocampal damage in TGA}, series = {Neurology : official journal of the American Academy of Neurology}, volume = {92}, journal = {Neurology : official journal of the American Academy of Neurology}, number = {3}, issn = {0028-3878}, doi = {10.1212/WNL.0000000000006779}, pages = {e234 -- e243}, abstract = {Objective To investigate long-term recovery of allocentric and egocentric spatial orientation as a sensitive marker for hippocampal and extrahippocampal network function in transient global amnesia (TGA). Methods A group of 18 patients with TGA performed an established real-space navigation paradigm, requiring allo- and egocentric spatial orientation abilities, 3 days (postacute stage) and 3 months (follow-up) after symptom onset. Visual exploration behavior and navigation strategy were documented by a gaze-controlled, head-fixed camera. Allo- and egocentric spatial orientation performance was compared to that of 12 age-matched healthy controls. Navigation-induced brain activations were measured using [18F]-fluorodeoxyglucose-PET in a subgroup of 8 patients in the postacute stage and compared to those of the controls. Results In the postacute stage, the patients navigated worse and had higher error rates than controls in allocentric (p = 0.002), but not in egocentric, route planning (p = 0.30), despite complete recovery of verbal (p = 0.58) and figural memory (p = 0.11). Until follow-up, allocentric navigation deficits improved, but higher error rates and reduced use of shortcuts persisted (p < 0.0001). Patients still exhibited relatively more fixations of unique landmarks during follow-up (p = 0.05). PET measurements during the postacute stage showed increased navigation-induced brain activations in the right hippocampus, bilateral retrosplenial, parietal, and mesiofrontal cortices, and cerebellar dentate nucleus in patients compared to controls (p < 0.005). Conclusions Patients with TGA show selective and prolonged deficits of allocentric spatial orientation. Activations in right hippocampal and extrahippocampal hubs of the cerebral navigation network functionally substitute for the deficit in creating and updating the internal cognitive map in TGA.}, language = {en} } @misc{GrillHeubergerStrobletal., author = {Grill, Eva and Heuberger, Maria and Strobl, Ralf and Saglam, Murat and Holle, Rolf and Linkohr, Birgit and Ladwig, Karl-Heinz and Peters, Annette and Schneider, Erich and Jahn, Klaus and Lehnen, Nadine}, title = {Prevalence, determinants, and consequences of vestibular hypofunction. results from the kora-ff4 survey}, series = {Frontiers in Neurology}, volume = {9}, journal = {Frontiers in Neurology}, issn = {1664-2295}, doi = {10.3389/fneur.2018.01076}, pages = {8}, abstract = {Objective: Uni- or bilateral vestibular hypofunction (VH) impairs balance and mobility, and may specifically lead to injury from falls and to disability. The extent of this problem in the general population is still unknown and most likely to be underestimated. Objective of this study was to determine the prevalence, determinants, and consequences of VH in the general population. Methods: Data originates from the cross-sectional second follow-up (FF4) in 2013/14 of the KORA (Cooperative Health Research in the Region of Augsburg)-S4 study (1999-2001) from Southern Germany. This was a random sample of the target population consisting of all residents of the region aged 25-74 years in 1999. We included all participants who reported moderate or severe vertigo or dizziness during the last 12 months and a random sub-sample of participants representative for the general population without vertigo or dizziness during the last 12 months were tested. VH was assessed with the Video-Head Impulse Test (vHIT). Trained examiners applied high-acceleration, small-amplitude passive head rotations ("head impulses") to the left and right in the plane of the horizontal semicircular canals while participants fixated a target straight ahead. During head impulses, head movements were measured with inertial sensors, eye movements with video-oculography (EyeSeeCam vHIT). Results: A total of 2,279 participants were included (mean age 60.8 years, 51.6\% female), 570 (25.0\%) with moderate or severe vertigo or dizziness during the last 12 months. Of these, 450 were assessed with vHIT where 26 (5.8\%) had unilateral VH, and 16 (3.6\%) had bilateral VH. Likewise, 190 asymptomatic participants were tested. Of these 5 (2.6\%) had unilateral VH, and 2 (1.1\%) had bilateral VH. Prevalence of uni- or bilateral VH among tested symptomatic participants was 2.4\% in those < 48 years, and 32.1\% in individuals aged 79 and over. Age-adjusted prevalence was 6.7\% (95\% CI 4.8\%; 8.6\%). VH was associated with worse health, falls, hearing loss, hearing impairment, and ear pressure. Conclusion: VH may affect between 53 and 95 million adults in Europe and the US. While not all affected persons will experience the full spectrum of symptoms and consequences, adequate diagnostic and therapeutic measures should become standard of care to decrease the burden of disease.}, language = {en} } @misc{DonaldTanChakrapanietal., author = {Donald, Aimee and Tan, Chong Y. and Chakrapani, Anupam and Hughes, Derralyn A. and Sharma, Reena and Cole, Duncan and Bardins, Stanislav and Gorges, Martin and Jones, Simon A. and Schneider, Erich}, title = {Eye movement biomarkers allow for the definition of phenotypes in Gaucher Disease}, series = {Orphanet journal of rare diseases : OJRD}, volume = {15}, journal = {Orphanet journal of rare diseases : OJRD}, issn = {1750-1172}, doi = {10.1186/s13023-020-01637-9}, pages = {12}, abstract = {Background: Neurological forms of Gaucher disease, the inherited disorder of β-Glucosylceramidase caused by bi-allelic variants in GBA1, is a progressive disorder which lacks a disease-modifying therapy. Systemic manifestations of disease are effectively treated with enzyme replacement therapy, however, molecules which cross the blood-brain barrier are still under investigation. Clinical trials of such therapeutics require robust, reproducible clinical endpoints to demonstrate efficacy and clear phenotypic definitions to identify suitable patients for inclusion in trials. The single consistent clinical feature in all patients with neuronopathic disease is the presence of a supranuclear saccadic gaze palsy, in the presence of Gaucher disease this finding serves as diagnostic of 'type 3' Gaucher disease.}, language = {en} } @misc{BelyakovaBodinaRatanovSchneideretal., author = {Belyakova-Bodina, Alexandra and Ratanov, Mikhail and Schneider, Erich and Seliverstov, Yury and Nuzhnyi, Evgenii and Klyushnikov, Sergey and Broutian, Amayak}, title = {Uncovering bilateral vestibulopathy in patients with SANDO syndrome caused by mutations in POLG gene: a case series}, series = {Journal of Neurology}, volume = {268}, journal = {Journal of Neurology}, number = {10}, issn = {1432-1459}, doi = {10.1007/s00415-021-10650-2}, pages = {3909 -- 3912}, abstract = {The triad of sensory ataxic neuropathy, dysarthria, and ophthalmoparesis (SANDO) comprise a distinct phenotype of rare mitochondrial disease. It is caused mainly by mitochondrial DNA depletion and deletions due to mutations in the nuclear genes, with POLG being one of the most common ones [1]. In SANDO syndrome, balance and gait disturbances have traditionally been attributed to sensory ataxic neuropathy and, in some patients, to cerebellar ataxia and/or limb weakness [2, 3]. However, there has been a report of bilateral vestibulopathy (BV) in a patient with SANDO caused by mutations in the POLG gene [4]. We present five patients with SANDO due to POLG gene mutations, whose vestibular and oculomotor function were assessed with video-oculography (VOG)}, language = {en} } @misc{KordaZamaroWagneretal., author = {Korda, Athanasia and Zamaro, Ewa and Wagner, Franca and Morrison, Miranda and Schneider, Erich and Caversaccio, Marco Domenico and Sauter, Thomas C. and Mantokoudis, Georgios}, title = {Acute vestibular syndrome: is skew deviation a central sign?}, series = {Journal of Neurology}, volume = {269}, journal = {Journal of Neurology}, number = {3}, issn = {1432-1459}, doi = {10.1007/s00415-021-10692-6}, pages = {1396 -- 1403}, abstract = {Objective Skew deviation results from a dysfunction of the graviceptive pathways in patients with an acute vestibular syndrome (AVS) leading to vertical diplopia due to vertical ocular misalignment. It is considered as a central sign, however, the prevalence of skew and the accuracy of its test is not well known . Methods We performed a prospective study from February 2015 until September 2020 of all patients presenting at our emergency department (ED) with signs of AVS. All patients underwent clinical HINTS and video test of skew (vTS) followed by a delayed MRI, which served as a gold standard for vestibular stroke confirmation. Results We assessed 58 healthy subjects, 53 acute unilateral vestibulopathy patients (AUVP) and 24 stroke patients. Skew deviation prevalence was 24\% in AUVP and 29\% in strokes. For a positive clinical test of skew, the cut-off of vertical misalignment was 3 deg with a very low sensitivity of 15\% and specificity of 98.2\%. The sensitivity of vTS was 29.2\% with a specificity of 75.5\%. Conclusions Contrary to prior knowledge, skew deviation proved to be more prevalent in patients with AVS and occurred in every forth patient with AUVP. Large skew deviations (> 3.3 deg), were pointing toward a central lesion. Clinical and video test of skew offered little additional diagnostic value compared to other diagnostic tests such as the head impulse test and nystagmus test. Video test of skew could aid to quantify skew in the ED setting in which neurotological expertise is not always readily available.}, language = {en} } @misc{SpiegelClaassenTeufeletal., author = {Spiegel, Rainer and Claassen, Jens and Teufel, Julian and Bardins, Stanislav and Schneider, Erich and Lehrer, Nicole and Jahn, Klaus and Anciaes da Silva, F{\´a}bio and Hahn, Ales and Farahmand, Parvis and Brandt, Thomas and Strupp, Michael and Kalla, Roger}, title = {Resting in darkness improves downbeat nystagmus: evidence from an observational study}, series = {Annals of the New York Academy of Sciences}, volume = {1375}, journal = {Annals of the New York Academy of Sciences}, number = {1}, issn = {1749-6632}, doi = {10.1111/nyas.13172}, pages = {66 -- 73}, abstract = {Resting in an upright position during daytime decreases downbeat nystagmus (DBN). When measured in brightness only, that is, without intermitting exposure to darkness, it does not make a significant difference whether patients have previously rested in brightness or in darkness. In real-world scenarios, people are often exposed to brightness and darkness intermittently. The aim of this study was to analyze whether resting in brightness or resting in darkness was associated with a lower post-resting DBN after intermitting exposures to brightness and darkness. Eight patients were recorded with three-dimensional video-oculography in brightness and darkness conditions, each following two 2-h resting intervals under either brightness or darkness resting conditions. The dependent variable was DBN intensity, measured in mean slow phase velocity. A repeated measures ANOVA with the factors measurement condition (brightness vs. darkness), resting condition (brightness vs. darkness), and time (after first vs. second resting interval) showed a significant effect for the factor resting condition, where previous resting in darkness was associated with a significantly lower DBN relative to previous resting in brightness (P < 0.01). The clinical relevance is to advise patients with DBN to rest in darkness.}, language = {en} } @inproceedings{VillgrattnerSchneiderAnderschetal., author = {Villgrattner, Thomas and Schneider, Erich and Andersch, Philipp and Ulbrich, Heinz}, title = {Compact high dynamic 3 dof camera orientation system, development and control}, series = {The 10th International Conference on Motion and Vibration Control MOVIC, proceedings, 17 - 20 August 2010, Tokyo, Japan}, booktitle = {The 10th International Conference on Motion and Vibration Control MOVIC, proceedings, 17 - 20 August 2010, Tokyo, Japan}, editor = {Suda, Yoshihiro}, publisher = {Institute of Industrial Science, the University of Tokyo}, address = {Tokyo}, pages = {10}, language = {en} } @inproceedings{WrightSchneider, author = {Wright, W. Geoffrey and Schneider, Erich}, title = {Manual motor control during "virtual" self-motion: Implications for vr rehabilitation}, series = {2009 Virtual Rehabilitation International Conference, Haifa, Israel, 29 June - 2 July 2009}, booktitle = {2009 Virtual Rehabilitation International Conference, Haifa, Israel, 29 June - 2 July 2009}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4244-4188-4}, pages = {166 -- 172}, language = {en} } @misc{AubeleGrillEggertetal., author = {Aubele, Maria and Grill, Eva and Eggert, Thomas and Schneider, Erich and Strobl, Ralf and Jahn, Klaus and M{\"u}ller, Martin and Holle, Rolf and Linkohr, Birgit and Heier, Margit and Ladwig, Karl-Heinz and Lehnen, Nadine}, title = {Symptoms in unilatral vestibular hypofunction are associated with number of catch-up saccades and retinal errors: results from the population-based KORA FF4study}, series = {Frontiers in Neurology}, volume = {2023}, journal = {Frontiers in Neurology}, number = {14}, issn = {1664-2295}, pages = {8}, abstract = {Objective: The presence and intensity of symptoms vary in patients with unilateral vestibular hypofunction. We aimed to determine which saccadic and vestibulo-ocular reflex parameters best predict the presence of symptoms in unilateral vestibular hypofunction in order to better understand vestibular compensation and its implications for rehabilitation therapy. Methods: Video head impulse test data were analyzed from a subpopulation of 23 symptomatic and 10 currently symptom-free participants with unilateral vestibular hypofunction, embedded in the KORA (Cooperative Health Research in the Region of Augsburg) FF4 study, the second follow-up of the KORA S4 population-based health survey (2,279 participants). Results: A higher number of catch-up saccades, a higher percentage of covert saccades, and a larger retinal error at 200 ms after the onset of the head impulse were associated with relevant symptoms in participants with unilateral vestibular hypofunction (p = 0.028, p = 0.046, and p = 0.038, respectively). After stepwise selection, the number of catch-up saccades and retinal error at 200 ms remained in the final logistic regression model, which was significantly better than a null model (p = 0.014). Age, gender, saccade amplitude, saccade latency, and VOR gain were not predictive of the presence of symptoms. Conclusion: The accuracy of saccadic compensation seems to be crucial for the presence of symptoms in unilateral vestibular hypofunction, highlighting the role of specific gaze stabilization exercises in rehabilitation. Early saccades, mainly triggered by the vestibular system, do not seem to compensate accurately enough, resulting in a relevant retinal error and the need for more as well as more accurate catch-up saccades, probably triggered by the visual system.}, language = {en} } @misc{MichailidouKordaWyssetal., author = {Michailidou, Efterpi and Korda, Athanasia and Wyss, Thomas and Bardins, Stanislav and Schneider, Erich and Morrison, Miranda and Wagner, Franca and Caversaccio, Marco and Mantokoudis, Georgios}, title = {The value of saccade metrics and VOR gain in detecting a vestibular stroke}, series = {Journal of Vestibular Research}, volume = {34}, journal = {Journal of Vestibular Research}, number = {1}, issn = {1878-6464}, doi = {10.3233/VES-230083}, pages = {49 -- 61}, abstract = {Objective: A normal video Head Impulse Test is the gold standard in the emergency department to rule-in patients with an acute vestibular syndrome and a stroke. We aimed to compare the diagnostic accuracy of vHIT metrics regarding the vestibulo-ocular reflex gain and the corrective saccades in detecting vestibular strokes. Methods: Prospective cross-sectional study (convenience sample) of patients presenting with acute vestibular syndrome in the emergency department of a tertiary referral centre between February 2015 and May 2020. We screened 1677 patients and enrolled 76 patients fulfilling the inclusion criteria of acute vestibular syndrome. All patients underwent video head impulse test with automated and manual data analysis. A delayed MRI served as a gold standard for vestibular stroke confirmation. Results: Out of 76 patients, 52 were diagnosed with acute unilateral vestibulopathy and 24 with vestibular strokes. The overall accuracy of detecting stroke with an automated vestibulo-ocular reflex gain was 86.8\%, compared to 77.6\% for cumulative saccade amplitude and automatic saccade mean peak velocity measured by an expert and 71\% for cumulative saccade amplitude and saccade mean peak velocity measured automatically. Gain misclassified 13.1\% of the patients as false positive or false negative, manual cumulative saccade amplitude and saccade mean peak velocity 22.3\%, and automated cumulative saccade amplitude and saccade mean peak velocity 28.9\% respectively. Conclusions: We found a better accuracy of video head impulse test for the diagnosis of vestibular strokes when using the vestibulo-ocular reflex gain than using saccade metrics. Nevertheless, saccades provide an additional and important information for video head impulse test evaluation. The automated saccade detection algorithm is not yet perfect compared to expert analysis, but it may become a valuable tool for future non-expert video head impulse test evaluations.}, language = {en} } @misc{LehnenRamaioliToddetal., author = {Lehnen, Nadine and Ramaioli, Cecilia and Todd, Nicholas Sean and Bartl, Klaus and Kohlbecher, Stefan and Jahn, Klaus and Schneider, Erich}, title = {Clinical and video head impulses: a simple bedside test in children}, series = {Journal of Neurology}, volume = {264}, journal = {Journal of Neurology}, number = {5}, issn = {1432-1459}, doi = {10.1007/s00415-017-8450-y}, pages = {1002 -- 1004}, language = {en} } @misc{FriedrichSchneiderBuerkleinetal., author = {Friedrich, Maximilian U. and Schneider, Erich and Buerklein, Miriam and Taeger, Johannes and Hartig, Johannes and Volkmann, Jens and Peach, Robert and Zeller, Daniel}, title = {Smartphone video nystagmography using convolutional neural networks: ConVNG}, series = {Journal of Neurology}, volume = {270}, journal = {Journal of Neurology}, issn = {1432-1459}, doi = {10.1007/s00415-022-11493-1}, pages = {2518 -- 2530}, abstract = {Eye movement abnormalities are commonplace in neurological disorders. However, unaided eye movement assessments lack granularity. Although videooculography (VOG) improves diagnostic accuracy, resource intensiveness precludes its broad use. To bridge this care gap, we here validate a framework for smartphone video-based nystagmography capitalizing on recent computer vision advances. Methods A convolutional neural network was fine-tuned for pupil tracking using > 550 annotated frames: ConVNG. In a cross-sectional approach, slow-phase velocity of optokinetic nystagmus was calculated in 10 subjects using ConVNG and VOG. Equivalence of accuracy and precision was assessed using the "two one-sample t-test" (TOST) and Bayesian interval-null approaches. ConVNG was systematically compared to OpenFace and MediaPipe as computer vision (CV) benchmarks for gaze estimation. Results ConVNG tracking accuracy reached 9-15\% of an average pupil diameter. In a fully independent clinical video dataset, ConVNG robustly detected pupil keypoints (median prediction confidence 0.85). SPV measurement accuracy was equivalent to VOG (TOST p < 0.017; Bayes factors (BF) > 24). ConVNG, but not MediaPipe, achieved equivalence to VOG in all SPV calculations. Median precision was 0.30°/s for ConVNG, 0.7°/s for MediaPipe and 0.12°/s for VOG. ConVNG precision was significantly higher than MediaPipe in vertical planes, but both algorithms' precision was inferior to VOG. Conclusions ConVNG enables offline smartphone video nystagmography with an accuracy comparable to VOG and significantly higher precision than MediaPipe, a benchmark computer vision application for gaze estimation. This serves as a blueprint for highly accessible tools with potential to accelerate progress toward precise and personalized Medicine.}, language = {en} } @misc{DongHanSchneiderSangYeonetal., author = {Dong-Han, Lee and Schneider, Erich and Sang-Yeon, Lee and Kim, Ji-Soo and Koo, Ja-Won}, title = {Objective measurement of HINTS (Head Impulse, Nystagmus, Test of Skew) in peripheral vestibulopathy}, series = {Auris Nasus Larynx}, volume = {49}, journal = {Auris Nasus Larynx}, number = {6}, issn = {1879-1476}, doi = {10.1016/j.anl.2022.03.003}, pages = {938 -- 949}, abstract = {ABSTRACT Objective To evaluate how often the positive sign of HINTS (Head-Impulse, Gaze Evoked Nystagmus, Test of Skew) appears in patients with acute peripheral vestibular lesion, HINTS findings were quantitatively measured and analyzed in patients with peripheral vestibulopathy accompanying spontaneous nystagmus. Methods HINTS was evaluated in 14 vertigo patients with spontaneous nystagmus. Horizontal vestibulo-ocular reflex (VOR) gain was measured using the video head impulse test (vHIT). To evaluate gaze-evoked nystagmus (GEN), slow-phase velocities at different points of lateral gaze were measured and plotted, then the slope and its inverse value, the neural integrator time constant, were calculated. Skew deviation was tested using anaglyph filters to simulate the alternate cover test, and the degree and latency of vertical eyeball deviation were measured. The ABCD2 score was calculated to evaluate the risk of stroke. Results Among 13 patients of peripheral vestibulopathy, 7 showed positive signs in HINTS (normal vHIT: 5, direction-changing GEN: 0, skew deviation: 3). One patient with a cerebellopontine angle tumor presented with both a peripheral and central pattern and showed positive HINTS findings (presence of direction-changing GEN). The mean VOR gain of patients with abnormal vHIT was 0.58±0.29 and 1.10±0.11 in the affected and contralateral side, respectively, while those in patients with normal vHIT were 1.04±0.21 and 1.13±0.12, respectively. The neural integrator time constant calculated from the mean slope of horizontal slow-phase velocity according to horizontal eye position was 42.9 s. The mean vertical eyeball deviation of patients with positive skew was 2.14±1.18° while uncovering the eye on the affected side, and -1.97±1.59° while uncovering the eye on the unaffected side. The median ABCD2 score of 14 patients was 2 (range, 1-3). Conclusions HINTS findings were objectively measured in vertigo patients with spontaneous nystagmus. Although positive findings of HINTS have been recognized as a central sign, 54\% (7/13) of cases with peripheral vestibulopathy showed positive HINTS signs. HINTS results should be interpreted carefully considering that a substantial proportion of peripheral vestibulopathy shows a positive HINTS sign.}, language = {en} } @misc{LehnenSchneiderJahn, author = {Lehnen, Nadine and Schneider, Erich and Jahn, Klaus}, title = {Do neurologists need the head impulse test?}, series = {Nervenarzt}, volume = {84}, journal = {Nervenarzt}, number = {8}, issn = {0028-2804}, doi = {10.1007/s00115-013-3822-8}, pages = {973 -- 974}, language = {de} } @misc{BrandtGlasauerSchneider, author = {Brandt, Thomas and Glasauer, Stefan and Schneider, Erich}, title = {Aufnahmevorrichtung f{\"u}r die kopfgest{\"u}tzte Bilderfassung und Verfahren zur Steuerung der Aufnahmevorrichtung}, language = {de} } @misc{JahnSchneider, author = {Jahn, Klaus and Schneider, Erich}, title = {Untersuchung der vestibul{\"a}ren Funktion bei Schwindelpatienten}, series = {Nervenheilkunde}, volume = {31}, journal = {Nervenheilkunde}, number = {5}, issn = {0722-1541}, pages = {370 -- 377}, language = {de} } @misc{SmythMossmanWeatheralletal., author = {Smyth, Duncan and Mossman, Stuart and Weatherall, Mark and Jolliffe, Evan and Joshi, Purwa and Taylor, Jennifer and Thorne, Katie and Watson, Eloise and Leadbetter, Ruth and Mossman, Benjamin and Moss, Tawhai and Todd, Nicholas Sean and Schneider, Erich}, title = {Gentamicin vestibulotoxicity with modern systemic dosing regimens : a prospective study using videooculography}, series = {Acta Oto-Laryngologica}, volume = {139}, journal = {Acta Oto-Laryngologica}, number = {9}, doi = {10.1080/00016489.2019.1637935}, pages = {759 -- 768}, abstract = {Objectives: To determine the incidence of gentamicin vestibulotoxicity with current dosing regimens, and to evaluate the feasibility of routine video-oculography on all patients given gentamicin. Materials and methods: In this prospective incidence study serial horizontal vestibulo-ocular reflex (HVOR) gain measurements were recorded using video-oculography on adult inpatients receiving intravenous gentamicin. The primary outcome was the proportion of patients developing impairment of their HVOR gain. Results: After exclusions, 42 patients were included in the analysis. Three patients (7.1\%) developed asymptomatic vestibulotoxicity, exact 95\% confidence interval 1.5-19.5\%. In two of these patients the deficit resolved within several hours. No patients developed symptomatic vestibulotoxicity. There was no evidence for a generalised reduction in group HVOR gain with time. HVOR gain was not associated with total gentamicin dose, dynamic visual acuity or subjective imbalance. Conclusions and significance: Gentamicin may cause reversible, asymptomatic vestibulotoxicity. Video-oculography may be useful to monitor for vestibulotoxicity in patients treated with gentamcin; however, testing all patients routinely may be challenging.}, language = {en} } @misc{FeilClaassenBrandinsetal., author = {Feil, Katharina and Claassen, Jens and Brandins, Stanislavs and Teufel, Julian and Krafczyk, Siegbert and Schneider, Erich}, title = {Effect of chlorzoxazone in patients with downbeat nystagmus: a pilot trial}, series = {Neurology}, volume = {81}, journal = {Neurology}, number = {13}, issn = {0028-3878}, doi = {10.1212/WNL.0b013e3182a55f6d}, pages = {1152 -- 1158}, language = {en} } @misc{SchoeberlPradhanIrvingetal., author = {Sch{\"o}berl, Florian and Pradhan, Cauchy and Irving, Stephanie and Buerger, Katharina and Xiong, Guoming and Kugler, G{\"u}nter and Kohlbecher, Stefan and Engmann, Julia and Werner, Philipp and Brendel, Matthias and Schneider, Erich and Perneczky, Robert and Jahn, Klaus and Foug{\`e}re, Christian la and Bartenstein, Peter and Brandt, Thomas and Dietrich, Marianne and Zwergal, Andreas}, title = {Real-space navigation testing differentiates between amyloid-positive and -negative aMCI}, series = {Neurology : official journal of the American Academy of Neurology}, volume = {94}, journal = {Neurology : official journal of the American Academy of Neurology}, number = {8}, issn = {1526-632X}, doi = {10.1212/WNL.0000000000008758}, pages = {e861 -- e873}, language = {en} } @misc{KallaSpiegelClaassenetal., author = {Kalla, Roger and Spiegel, Rainer and Claassen, Jens and Bardins, Stanislav and Hahn, Ales and Schneider, Erich and Lehrer, Nicole and Glasauer, Stefan and Brandt, Thomas and Strupp, Michael}, title = {Comparison of 10-mg doses of 4-aminopyridine and 3,4-diaminopyridine for the treatment of downbeat nystagmus}, series = {Journal of neuro-ophthalmology}, volume = {32}, journal = {Journal of neuro-ophthalmology}, number = {2}, issn = {1536-5166}, doi = {10.1097/WNO.0b013e3182258086}, pages = {320 -- 325}, language = {en} } @misc{SchulzSchneiderFritzetal., author = {Schulz, Christian M. and Schneider, Erich and Fritz, L. and Vockeroth, Johannes and Hapfelmeier, Alexander and Wasmaier, M.}, title = {Eye tracking for assessment of workload: a pilot study in an anaesthesia simulator environment}, series = {British journal of anaesthesia}, volume = {106}, journal = {British journal of anaesthesia}, number = {1}, issn = {1471-6771}, doi = {10.1093/bja/aeq307}, pages = {44 -- 50}, language = {en} } @misc{SchulzSchneiderFritzetal., author = {Schulz, Christian M. and Schneider, Erich and Fritz, L. and Vockeroth, Johannes and Hapfelmeier, Alexander and Brandt, Thomas}, title = {Visual attention of anaesthetists during simulated critical incidents}, series = {British Journal of Anaesthesia}, volume = {106}, journal = {British Journal of Anaesthesia}, number = {6}, issn = {1471-6771}, doi = {10.1093/bja/aer087}, pages = {807 -- 813}, language = {en} } @misc{MorrisonKerkeniKordaetal., author = {Morrison, Miranda and Kerkeni, Hassen and Korda, Athanasia and R{\"a}ss, Simone and Caversaccio, Marco Domenico and Abegg, Mathias and Schneider, Erich and Mantokoudis, Georgios}, title = {Automated alternate cover test for 'HINTS' assessment: a validation study}, series = {European archives of oto-rhino-laryngology and head \& neck}, journal = {European archives of oto-rhino-laryngology and head \& neck}, issn = {1434-4726}, doi = {10.1007/s00405-021-06998-w}, pages = {2873 -- 2879}, abstract = {Objective The alternate cover test (ACT) in patients with acute vestibular syndrome is part of the 'HINTS' battery test. Although quantitative, the ACT is highly dependent on the examiner's experience and could theoretically vary greatly between examiners. In this study, we sought to validate an automated video-oculography (VOG) system based on eye tracking and dedicated glasses. Methods We artificially induced a vertical strabismus to simulate a skew deviation on ten healthy subjects, aged from 26 to 66, using different press-on Fresnel prisms on one eye while recording eye position with VOG of the contralateral eye. We then compared the system's performance to that of a blinded trained orthoptist using conventional, semi-quantitative method of skew measurement known as the alternate prism cover test (APCT) as a gold standard. Results We found a significant correlation between the reference APCT and the Skew VOG (Pearson's R2 = 0.606, p < 0.05). There was a good agreement between the two tests (intraclass correlation coefficient 0.852, 95 CI 0.728-0.917, p < 0.001). The overall accuracy of the VOG was estimated at 80.53\% with an error rate of 19.46\%. There was no significant difference in VOG skew estimations compared with the gold standard except for very small skews. Conclusions VOG offers an objective and quantitative skew measurement and proved to be accurate in measuring vertical eye misalignment compared to the ACT with prisms. Precision was moderate, which mandates a sufficient number of tests per subject.}, language = {en} } @misc{KuglerHuppertSchneideretal., author = {Kugler, G{\"u}nter and Huppert, Doreen and Schneider, Erich and Brandt, Thomas}, title = {Wie H{\"o}henschwindel die visuelle Exploration und den Gang beeintr{\"a}chtigt}, series = {Nervenarzt}, volume = {84}, journal = {Nervenarzt}, number = {10}, issn = {0028-2804}, doi = {10.1007/s00115-013-3905-6}, pages = {1233 -- 1237}, language = {de} } @misc{LehnenSchneiderJahn, author = {Lehnen, Nadine and Schneider, Erich and Jahn, Klaus}, title = {Klinische Untersuchungen bei Schwindel: Kopfimpulstest und dynamische Sehsch{\"a}rfe}, series = {Neurotransmitter}, volume = {24}, journal = {Neurotransmitter}, number = {4}, issn = {2196-6397}, pages = {39 -- 43}, language = {de} } @misc{TeufelBardinsSpiegeletal., author = {Teufel, Julian and Bardins, Stanislav and Spiegel, Rainer and Kremmyda, O. and Schneider, Erich and Strupp, Michael and Kalla, R.}, title = {Real time computerbased visual feedback improves visual acuity in downbeat nystagmus, a pilot study}, series = {Journal of NeuroEngineering and Rehabilitation}, volume = {13}, journal = {Journal of NeuroEngineering and Rehabilitation}, number = {1}, issn = {1743-0003}, language = {de} } @misc{GuinandVandeBergCavuscensetal., author = {Guinand, Nils and Van de Berg, Raymond and Cavuscens, Samuel and Ranieri, Maurizio and Schneider, Erich and Lucieer, Floor and Kingma, Hermann and Guyot, Jean-Philippe and Perez Fornos, Angelica}, title = {The Video Head Impulse Test to Assess the Efficacy of Vestibular Implants in Humans}, series = {Frontiers in neurology}, volume = {8}, journal = {Frontiers in neurology}, issn = {1664-2295}, doi = {10.3389/fneur.2017.00600}, pages = {13}, language = {en} } @misc{LuisCostaMunozetal., author = {Luis, L. and Costa, Jo{\~a}o and Mu{\~n}oz, E. and Carvalho, M. de and Carmona, S. and Schneider, Erich}, title = {Vestibulo-ocular reflex dynamics with head-impulses discriminates spinocerebellar ataxias types 1, 2 and 3 and Friedreich ataxia.}, series = {Journal of Vestibular Research}, volume = {26}, journal = {Journal of Vestibular Research}, number = {3}, issn = {0957-4271}, doi = {10.3233/VES-160579}, pages = {327 -- 334}, language = {en} } @misc{KellerGorgesAhoOezhanetal., author = {Keller, J{\"u}rgen and Gorges, Martin and Aho-{\"O}zhan, Helena Eira Anneli and Carmona, S. and Schneider, Erich}, title = {Eye-tracking control to assess cognitive functions in patients with amyotrophic lateral sclerosis}, series = {JoVE}, volume = {116}, journal = {JoVE}, issn = {1940-087X}, doi = {10.3791/54634}, pages = {e54634}, language = {en} } @misc{LuisLehnenMunozetal., author = {Luis, L. and Lehnen, Nadine and Mu{\~n}oz, E. and Carvalho, M. de and Schneider, Erich}, title = {Anticompensatory quick eye movements after head impulses: A peripheral vestibular sign in spontaneous nystagmus}, series = {Journal of Vestibular Research}, volume = {25}, journal = {Journal of Vestibular Research}, number = {5-6}, issn = {0957-4271}, doi = {10.3233/VES-160566}, pages = {267 -- 271}, language = {en} } @misc{MossmanMossmanPurdieetal., author = {Mossman, Benjamin and Mossman, Stuart and Purdie, Gordon and Schneider, Erich}, title = {Age dependent normal horizontal vor gain of head impulse test as measured with video-oculography}, series = {Journal of Otolaryngology - Head \& Neck Surgery}, volume = {44}, journal = {Journal of Otolaryngology - Head \& Neck Surgery}, issn = {1916-0216}, doi = {10.1186/s40463-015-0081-7}, pages = {29}, language = {en} } @misc{SpiegelKallaRettingeretal., author = {Spiegel, Rainer and Kalla, R. and Rettinger, N. and Schneider, Erich and Straumann, D. and Marti, S. and Glasauer, Stefan}, title = {Head position during resting modifies spontaneous daytime decrease of downbeat nystagmus}, series = {Neurology}, volume = {75}, journal = {Neurology}, number = {21}, issn = {0028-3878}, doi = {10.1212/WNL.0b013e3181feb22f}, pages = {1928 -- 1932}, language = {en} } @misc{WrightSchneiderGlasauer, author = {Wright, W. Geoffrey and Schneider, Erich and Glasauer, Stefan}, title = {Compensatory manual motor responses while object wielding during combined linear visual and physical roll tilt stimulation}, series = {Experimental Brain Research}, volume = {192}, journal = {Experimental Brain Research}, number = {4}, issn = {0014-4819}, doi = {10.1007/s00221-008-1581-8}, pages = {683 -- 694}, language = {en} } @misc{GuentherBartlNaudereretal., author = {Guenther, Anna L. and Bartl, Klaus and Nauderer, Josef and Schneider, Erich and Huesmann, Alexander and Brandt, Thomas and Glasauer, Stefan}, title = {Modalitydependent indication of the subjective vertical during combined linear and rotational movements}, series = {Annals of the New York Academy of Sciences}, volume = {1164}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, doi = {10.1111/j.1749-6632.2009.03849.x}, pages = {376 -- 379}, language = {en} } @misc{EinhaeuserSchumannVockerothetal., author = {Einh{\"a}user, Wolfgang and Schumann, Frank and Vockeroth, Johannes and Bartl, Klaus and Cerf, Moran and Harel, Jonathan and Schneider, Erich and K{\"o}nig, Peter}, title = {Distinct roles for eye and head movements in selecting salient image parts during natural exploration}, series = {Annals of the New York Academy of Sciences}, volume = {1164}, journal = {Annals of the New York Academy of Sciences}, issn = {1749-6632}, doi = {10.1111/j.1749-6632.2008.03714.x}, pages = {188 -- 193}, language = {en} } @misc{GlasauerSchneiderGrassoetal., author = {Glasauer, Stefan and Schneider, Erich and Grasso, Renato and Ivanenko, Yuri P.}, title = {Space-time relativity in self-motion reproduction}, series = {Journal of Neurophysiology}, volume = {97}, journal = {Journal of Neurophysiology}, number = {1}, issn = {0022-3077}, doi = {10.1152/jn.01243.2005}, pages = {451 -- 461}, language = {en} } @misc{EinhaeuserSchumannBardinsetal., author = {Einh{\"a}user, Wolfgang and Schumann, Frank and Bardins, Stanislav and Bartl, Klaus and B{\"o}ning, Guido and Schneider, Erich and K{\"o}nig, Peter}, title = {Human eyehead co-ordination in natural exploration}, series = {Network}, volume = {18}, journal = {Network}, number = {3}, issn = {0954-898X}, doi = {10.1080/09548980701671094}, pages = {267 -- 297}, language = {en} } @misc{ZinglerKryvosheySchneideretal., author = {Zingler, Vera C. and Kryvoshey, Dmytro and Schneider, Erich and Glasauer, Stefan and Brandt, Thomas and Strupp, Michael}, title = {A clinical test of otolith function: static ocular counterroll with passive head tilt.}, series = {Neuroreport}, volume = {17}, journal = {Neuroreport}, number = {6}, issn = {0959-4965}, pages = {611 -- 615}, language = {en} } @misc{NowakHermsdoerferSchneideretal., author = {Nowak, Dennis A. and Hermsd{\"o}rfer, Joachim and Schneider, Erich and Glasauer, Stefan}, title = {Moving objects in a rotating environment rapid prediction of coriolis and centrifugal force perturbations}, series = {Experimental Brain Research}, volume = {157}, journal = {Experimental Brain Research}, number = {2}, issn = {0014-4819}, doi = {10.1007/s00221-004-1839-8}, pages = {241 -- 254}, language = {en} } @misc{SchneiderGlasauerDieterichetal., author = {Schneider, Erich and Glasauer, Stefan and Dieterich, Marianne and Kalla, Roger and Brandt, Thomas}, title = {Diagnosis of vestibular imbalance in the blink of an eye}, series = {Neurology}, volume = {63}, journal = {Neurology}, number = {7}, issn = {0028-3878}, pages = {1209 -- 1216}, language = {en} } @misc{HayashiKanzakiEthoetal., author = {Hayashi, Yujiro and Kanzaki, Jin and Etho, Norihito and Higashino, Kazutaka and Goto, Fumiyuki and Schneider, Erich and Kunihiro, Takanobu}, title = {Three-dimensional analysis of nystagmus in benign paroxysmal positional vertigo. new insights into its pathophysiology}, series = {Journal of Neurology}, volume = {249}, journal = {Journal of Neurology}, number = {12}, issn = {0340-5354}, doi = {10.1007/s00415-002-0905-z}, pages = {1683 -- 1688}, language = {en} } @misc{SchneiderGlasauerDieterich, author = {Schneider, Erich and Glasauer, Stefan and Dieterich, Marianne}, title = {Comparison of human ocular torsion patterns during natural and galvanic vestibular stimulation}, series = {Journal of Neurophysiology}, volume = {87}, journal = {Journal of Neurophysiology}, number = {4}, issn = {0022-3077}, doi = {10.1152/jn.00558.2001}, pages = {2064 -- 2073}, language = {en} } @misc{StriteskaChovanecSteinmetzeretal., author = {Striteska, Maja and Chovanec, Martin and Steinmetzer, Tobias and Chrobok, Viktor and Profant, Oliver and Schneider, Erich and Kremlacek, Jan and Valis, Martin}, title = {Binocular video head impulse test: Normative data study}, series = {Frontiers in Neurology}, volume = {14}, journal = {Frontiers in Neurology}, issn = {1664-2295}, doi = {10.3389/fneur.2023.1153102}, abstract = {Introduction The video head impulse test (vHIT) evaluates the vestibulo-ocular reflex (VOR). It's usually recorded from only one eye. Newer vHIT devices allow a binocular quantification of the VOR. Purpose (Aim) To investigate the advantages of simultaneously recorded binocular vHIT (bvHIT) to detect the differences between the VOR gains of the adducting and the abducting eye, to define the most precise VOR measure, and to assess gaze dys/conjugacy. We aimed to establish normative values for bvHIT adducting/abducting eye VOR gains and to introduce the VOR dysconjugacy ratio (vorDR) between adducting and abducting eyes for bvHIT. Methods We enrolled 44 healthy adult participants in a cross-sectional, prospective study using a repeated-measures design to assess test-retest reliability. A binocular EyeSeeCam Sci 2 device was used to simultaneously record bvHIT from both eyes during impulsive head stimulation in the horizontal plane. Results Pooled bvHIT retest gains of the adducting eye significantly exceeded those of the abducting eye (mean (SD): 1.08 (SD = 0.06), 0.95 (SD = 0.06), respectively). Both adduction and abduction gains showed similar variability, suggesting comparable precision and therefore equal suitability for VOR asymmetry assessment. The pooled vorDR here introduced to bvHIT was 1.13 (SD = 0.05). The test-retest repeatability coefficient was 0.06. Conclusion Our study provides normative values reflecting the conjugacy of eye movement responses to horizontal bvHIT in healthy participants. The results were similar to a previous study using the gold-standard scleral search coil, which also reported greater VOR gains in the adducting than in the abducting eye. In analogy to the analysis of saccade conjugacy, we propose the use of a novel bvHIT dysconjugacy ratio to assess dys/conjugacy of VOR-induced eye movements. In addition, to accurately assess VOR asymmetry, and to avoid directional gain preponderance between adduction and abduction VOR-induced eye movements leading to monocular vHIT bias, we recommend using a binocular ductional VOR asymmetry index that compares the VOR gains of only the abduction or only the adduction movements of both eyes.}, language = {en} } @misc{RamaioliSteinmetzerBrietzkeetal., author = {Ramaioli, Cecilia and Steinmetzer, Tobias and Brietzke, Adrian and Meyer, Paul and Pham Xuan, Rebecca and Schneider, Erich and Gorges, Martin}, title = {Assessment of vestibulo-ocular reflex and its adaptation during stop-and-go car rides in motion sickness susceptible passengers}, series = {Experimental Brain Research}, volume = {241}, journal = {Experimental Brain Research}, number = {6}, issn = {1432-1106}, doi = {10.1007/s00221-023-06619-4}, pages = {1523 -- 1531}, abstract = {Motion sickness is a physiological condition that negatively impacts a person's comfort and will be an emerging condition in autonomous vehicles without proper countermeasures. The vestibular system plays a key role in the origin of motion sickness. Understanding the susceptibility and (mal) adaptive mechanisms of the highly integrated vestibular system is a prerequisite for the development of countermeasures. We hypothesize a differential association between motion sickness and vestibular function in healthy individuals with and without susceptibility for motion sickness. We quantified vestibular function by measuring the high-frequency vestibulo-ocular reflex (VOR) using video head impulse testing (vHIT) in 17 healthy volunteers before and after a 11 min motion sickness-inducing naturalistic stop-and-go car ride on a test track (Dekra Test Oval, Klettwitz, Germany). The cohort was classified as motion sickness susceptible (n = 11) and non-susceptible (n = 6). Six (out of 11) susceptible participants developed nausea symptoms, while a total of nine participants were free of these symptoms. The VOR gain (1) did not differ significantly between participant groups with (n = 8) and without motion sickness symptoms (n = 9), (2) did not differ significantly in the factor time before and after the car ride, and showed no interaction between symptom groups and time, as indicated by a repeated measures ANOVA (F(1,15) = 2.19, p = 0.16. Bayesian inference confirmed that there was "anecdotal evidence" for equality of gain rather than difference across groups and time (BF10 < 0.77). Our results suggest that individual differences in VOR measures or adaptation to motion sickness provocative stimuli during naturalistic stop-and-go driving cannot predict motion sickness susceptibility or the likelihood of developing motion sickness.}, language = {en} }