@misc{YasenchukMarchenkoBaigonakovaetal., author = {Yasenchuk, Yuri and Marchenko, Ekaterina and Baigonakova, Gulsharat and Gunther, Sergey and Kokorev, Oleg and Gunther, Victor and Chekalkin, Timofey and Topolnitskiy, Evgeniy and Obrosov, Aleksei and Kang, Ji-hoon}, title = {Study on tensile, bending, fatigue, and in-vivo behavior of porous SHS-TiNi alloy used as a bone substitute}, series = {Biomedical Materials}, volume = {16}, journal = {Biomedical Materials}, number = {2}, issn = {1748-605X}, doi = {10.1088/1748-605X/aba327}, pages = {14}, abstract = {Intermetallic porous SHS-TiNi alloys exhibit tangled and specific stress-strain characteristics. The article aims to evaluate the findings emanated from experiments using standard and proprietary instruments. Fatigue testing under repeated complex loading was used to measure the total number of load cycles to failure of SHS-TiNi samples. 70\% of the tested samples, passed through 106 cycles without failure due to the reversible martensite transformation in the TiNi phase, one of the prevailing constituents of a multiphase matrix. The fractured surfaces were analyzed using SEM and confocal laser scanning instruments. Microscopic studies showed that the entire surface of the sample is concealed with the miscellaneous strata resulted from the SHS process, which effectively protect the porous alloy in a corrosive environment. Numerous non-metallic inclusions, which are also attributed to the SHS reaction, do not have a significant impact on the deformation behavior and fatigue performance. In this context, the successful in vivo functioning of porous grafts assessed in a canine rib-plasty model allows the bone substitute to be congruentially deformed in the body without rejection and degradation, having a long operational life, often greater than 17 million cycles. It acknowledges the potential benefits of SHS-TiNi as a superior osteoplastic material and its high resistance to corrosion fatigue.}, language = {en} } @misc{MarchenkoBaigonakovaDubovikovetal., author = {Marchenko, Ekaterina and Baigonakova, Gulsharat and Dubovikov, Kirill and Yasenchuk, Yuri and Chekalkin, Timofey and Obrosov, Aleksei}, title = {Comparative study on the high-temperature oxidation resistance of porous and solid TiNi-based alloys}, series = {Surface Topography: Metrology and Properties}, volume = {9}, journal = {Surface Topography: Metrology and Properties}, number = {2}, issn = {2051-672X}, doi = {https://doi.org/10.1088/2051-672X/abf324}, abstract = {The present work aims to characterize the surface features of solid and porous (sintered and SHS) TiNi-based alloys subjected to oxidation at 1000 °C in static air in the context of their resistance to high-temperature atmospheric attack. Clear differences between the intact and oxidated surfaces indicate the complexity of a chemicothermal diffusion process evolving therein. Microscopic and XRD studies showed that the dominant superficial constituent in all oxidated samples is titanium dioxide in the rutile modification. The phase and structural properties of the surface layers suggest that porous sintered and solid alloys are most susceptible to high-temperature corrosion due to bare reactive surfaces, which negatively affects their overall biocompatibility. Surface morphology analysis revealed microporous and loose superficial layers having a thickness of 8-10 and 50-60 μm, respectively in the solid and sintered alloy. Also, these alloys showed a high content of leaching NiO and free Ni within the surface layer. Conversely, a thin (0.5-0.6 μm), dense, and multifarious layer of oxycarbonitrides Ti4Ni2(O,N,C) concealing the porous SHS-TiNi matrix inhibits the negative effect of high-temperature oxidation.}, language = {en} } @misc{TopolnitskiyChekalkinMarchenkoetal., author = {Topolnitskiy, Evgeniy and Chekalkin, Timofey and Marchenko, Ekaterina and Yasenchuk, Yuri and Kang, Seung-Baik and Kang, Ji-Hoon and Obrosov, Aleksei}, title = {Evaluation of Clinical Performance of TiNi-Based Implants Used in Chest Wall Repair after Resection for Malignant Tumors}, series = {Journal of Functional Biomaterials}, volume = {12}, journal = {Journal of Functional Biomaterials}, number = {4}, issn = {2079-4983}, doi = {10.3390/jfb12040060}, pages = {11}, abstract = {In this study, we assessed the outcomes after surgical treatment of thoracic post-excision defects in 15 patients, using TiNi knitted surgical meshes and customized artificial TiNi-based ribs. Methods: Eight patients were diagnosed with advanced non-small cell lung cancer (NSCLC) invading the chest wall, of which five patients were T3N0M0, two were T3N1M0, and one was T3N2M0. Squamous cell carcinoma was identified in three of these patients and adenocarcinoma in five. In two cases, chest wall resection and repair were performed for metastases of kidney cancer after radical nephrectomy. Three-dimensional CT reconstruction and X-ray scans were used to plan the surgery and customize the reinforcing TiNi-based implants. All patients received TiNi-based devices and were prospectively followed for a few years. Results: So far, there have been no lethal outcomes, and all implanted devices were consistent in follow-up examinations. Immediate complications were noted in three cases (ejection of air through the pleural drains, paroxysm of atrial fibrillation, and pleuritis), which were conservatively managed. In the long term, no complications, aftereffects, or instability of the thoracic cage were observed. Conclusion: TiNi-based devices used for extensive thoracic lesion repair in this context are promising and reliable biomaterials that demonstrate good functional, clinical, and cosmetic outcomes.}, language = {en} }