@inproceedings{EllingerMeisterGrosaetal., author = {Ellinger, Frank and Meister, Tilo and Grosa, Patrick and Jamshidi, Kambiz and Ihle, David and Franchi, Norman and Wagner, Jens and Richter, Andreas and Fettweis, Gerhard and Fitzek, Frank and Kreissig, Martin and Klessig, Henrik and Kraemer, Rolf and Richter, Klaus and Frotzscher, Andreas and L{\"o}hr, Robert and Winkler, Wolfgang and Zoeke, Dominik and Carot, Alexander and Bluschke, Andreas}, title = {Project FAST - Fast Actuators Sensors \& Transceivers}, series = {Microwave Conference (LAMC), IEEE MTT-S Latin America, 12-14 Dec. 2016 Puerto Vallarta, Mexico}, booktitle = {Microwave Conference (LAMC), IEEE MTT-S Latin America, 12-14 Dec. 2016 Puerto Vallarta, Mexico}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-5090-4287-6}, pages = {3}, language = {en} } @misc{StaronBeckmannLippmannetal., author = {Staron, Peter and Beckmann, Felix and Lippmann, Thomas and Stark, Andreas and Oehring, Michael and Pyczak, Florian and Salgado, Mario and Hort, Norbert and Eckerlebe, Horst and Kainer, Karl Ulrich and M{\"u}ller, Martin and Schreyer, Andreas}, title = {In situ studies of light metals with synchrotron radiation and neutrons}, series = {Materials Science Forum}, journal = {Materials Science Forum}, number = {690}, issn = {1662-9752}, pages = {192 -- 197}, language = {en} } @misc{PreinGobietSuklitschetal., author = {Prein, Andreas and Gobiet, Andreas and Suklitsch, Martin and Truhetz, Heimo and Awan, N. K. and Keuler, Klaus and Georgievski, Goran}, title = {Added value of convection permitting seasonal simulations}, series = {Climate Dynamics}, volume = {41}, journal = {Climate Dynamics}, doi = {10.1007/s00382-013-1744-6}, pages = {2655 -- 2677}, language = {en} } @misc{KendaKraftTortschanoffetal., author = {Kenda, Andreas and Kraft, Martin and Tortschanoff, Andreas and Scherf, Werner and Sandner, Thilo and Schenk, Harald and Luettjohann, Stephan and Simon, Apolline}, title = {Development, characterization and application of compact spectrometers based on MEMS with in-plane capacitive drives}, series = {Next-generation spectroscopic technologies VII, 5 - 6 May 2014, Baltimore, Maryland, United States}, journal = {Next-generation spectroscopic technologies VII, 5 - 6 May 2014, Baltimore, Maryland, United States}, publisher = {SPIE}, address = {Bellingham, Wash.}, isbn = {978-1-62841-038-9}, pages = {910102-1 -- 910102-10}, language = {en} } @misc{EisenhauerFrankWeigeltetal., author = {Eisenhauer, Nico and Frank, Karin and Weigelt, Alexandra and Bartkowski, Bartosz and Beugnon, R{\´e}my and Liebal, Katja and Mahecha, Miguel and Quaas, Martin and Al-Halbouni, Djamil and Bastos, Ana and Bohn, Friedrich J. and Brito, Mariana Madruga de and Denzler, Joachim and Feilhauer, Hannes and Fischer, Rico and Fritsche, Immo and Guimaraes-Steinicke, Claudia and H{\"a}nsel, Martin and Haun, Daniel B. M. and Herrmann, Hartmut and Huth, Andreas and Kalesse-Los, Heike and Koetter, Michael and Kolleck, Nina and Krause, Melanie and Kretschmer, Marlene and Leit{\~a}o, Pedro J. and Masson, Torsten and Mora, Karin and M{\"u}ller, Birgit and Peng, Jian and P{\"o}hlker, Mira L. and Ratzke, Leonie and Reichstein, Markus and Richter, Solveig and R{\"u}ger, Nadja and S{\´a}nchez-Parra, Beatriz and Shadaydeh, Maha and Sippel, Sebastian and Tegen, Ina and Thr{\"a}n, Daniela and Umlauft, Josefine and Wendisch, Manfred and Wolf, Kevin and Wirth, Christian and Zacher, Hannes and Zaehle, S{\"o}nke and Quaas, Johannes}, title = {A belowground perspective on the nexus between biodiversity change, climate change, and human well-being}, series = {Journal of Sustainable Agriculture and Environment}, volume = {3}, journal = {Journal of Sustainable Agriculture and Environment}, number = {2}, publisher = {Wiley}, issn = {2767-035X}, doi = {10.1002/sae2.12108}, pages = {12}, abstract = {Soil is central to the complex interplay among biodiversity, climate, and society. This paper examines the interconnectedness of soil biodiversity, climate change, and societal impacts, emphasizing the urgent need for integrated solutions. Human-induced biodiversity loss and climate change intensify environmental degradation, threatening human well-being. Soils, rich in biodiversity and vital for ecosystem function regulation, are highly vulnerable to these pressures, affecting nutrient cycling, soil fertility, and resilience. Soil also crucially regulates climate, influencing energy, water cycles, and carbon storage. Yet, climate change poses significant challenges to soil health and carbon dynamics, amplifying global warming. Integrated approaches are essential, including sustainable land management, policy interventions, technological innovations, and societal engagement. Practices like agroforestry and organic farming improve soil health and mitigate climate impacts. Effective policies and governance are crucial for promoting sustainable practices and soil conservation. Recent technologies aid in monitoring soil biodiversity and implementing sustainable land management. Societal engagement, through education and collective action, is vital for environmental stewardship. By prioritizing interdisciplinary research and addressing key frontiers, scientists can advance understanding of the soil biodiversity-climate change-society nexus, informing strategies for environmental sustainability and social equity.}, language = {en} } @incollection{UlrichSchlegelMertensetal., author = {Ulrich, Rainer G. and Schlegel, Matthias and Mertens, Marc and Groschup, Martin H. and Schmidt-Chanasit, Jonas and Plenge-B{\"o}nig, Anita and Jacob, Jens and Pelz, Hans-Joachim and Freise, Jona and Wenk, Matthias and Thiel, J{\"o}rg and Triebenbacher, Cornelia and Schmolz, Eric and Kurth, Andreas and Kr{\"u}ger, Frank and R{\"u}he, Ferdinand and Kiffner, Christian and Ansorge, Hermann and Gerwin, Werner and Wegener, Wolfgang and M{\"u}ller, J{\"o}rg and Bemmann, Margit and Wolf, Ronny and Otto, Lutz-Florian and Oehme, Rainer and Pfeffer, Martin and Heckel, Gerald and Schex, Susanne and Essbauer, Sandra S.}, title = {Netzwerk Nagetier-{\"u}bertragene Pathogene: Monitoring von Hantavirus-Infektionen in Deutschland}, series = {Wildhygiene, Wildtierkrankheiten, Parasiten, Epidemiologie}, booktitle = {Wildhygiene, Wildtierkrankheiten, Parasiten, Epidemiologie}, publisher = {Ges. f{\"u}r Wildtier- und Jagdforschung}, address = {Halle/Saale}, isbn = {978-378-88131-2-3}, issn = {1436-3895}, pages = {229 -- 250}, language = {de} } @misc{KleefeldReissel, author = {Kleefeld, Andreas and Reißel, Martin}, title = {The Levenberg-Marquardt method applied to a parameter estimation problem arising from electrical resistivity tomography}, series = {Journal of Applied Mathematics and Computation}, volume = {217}, journal = {Journal of Applied Mathematics and Computation}, number = {9}, issn = {0096-3003}, pages = {4490 -- 4501}, abstract = {An efficient and robust electrical resistivity tomographic inversion algorithm based on the Levenberg-Marquardt method is considered to obtain quantities like grain size, source discrimination and particle size distribution. The corresponding model in two-dimensions is based on the Maxwell equations and leads to a partial differential equation with mixed Dirichlet-Neumann boundary conditions. The forward problem is solved numerically with the finite-difference method. However, the inverse problem at hand is a classic nonlinear and ill-posed parameter estimation problem. Linearizing it and applying the Tikhonov regularization method yields an iterative scheme, the Levenberg-Marquardt method. Several systems of equations of large size have to be solved efficiently in each iteration step which is accomplished by the conjugate gradient method without setting up the corresponding matrix. Instead fast matrix-vector multiplications are performed directly. Therefore, the derivative and its adjoint for the parameter-to-solution map are needed. Numerical results demonstrate the performance of our method as well as the possibility to reconstruct some of the desired parameters.}, language = {en} } @misc{HoZschechSchmeisseretal., author = {Ho, Paul S. and Zschech, Ehrenfried and Schmeißer, Dieter and Meyer, Moritz Andreas and Huebner, Rene and Hauschildt, Meike and Zhang, Lijuan and Gall, Martin and Kraatz, Matthias}, title = {Scaling effects on microstructure and reliability for cu interconnects}, language = {en} } @misc{WaetzoldDrechslerArmstrongetal., author = {W{\"a}tzold, Frank and Drechsler, Martin and Armstrong, Claire W. and Baumg{\"a}rtner, Stefan and Grimm, Volker and Huth, Andreas and Perrings, Charles and Possingham, Hugh P. and Shogren, Jason F. and Skonhoft, Anders and Verboom-Vasiljev, Jana and Wissel, Christian}, title = {Ecological-economic modeling for biodiversity management: Potential, pitfalls, prospects}, language = {en} } @misc{SchlofferIqbalGabrischetal., author = {Schloffer, Martin and Iqbal, Farasat and Gabrisch, Heike and Schwaighofer, Emanuel and Schimansky, Frank-Peter and Mayer, Svea and Stark, Andreas and Lippmann, Thomas and G{\"o}ken, Mathias and Pyczak, Florian and Clemens, Helmut}, title = {Microstructure development and hardness of a powder metallurgical multi phase gamma-TiAl based alloy}, series = {Intermetallics}, journal = {Intermetallics}, number = {22}, issn = {0966-9795}, doi = {10.1016/j.intermet.2011.11.015}, pages = {231 -- 240}, language = {en} } @inproceedings{HauschildtStarkLorenzetal., author = {Hauschildt, Katja and Stark, Andreas and Lorenz, Uwe and Schell, Norbert and Fischer, Torben and Blankenburg, Malte and M{\"u}ller, Martin and Pyczak, Florian}, title = {Diffusion brazing of γ-TiAl-alloys: Investigations of the joint by electron microscopy and high-energy X-ray diffraction}, series = {Intermetallic-based alloys - science, technology and applications, symposium held November 25-30, Boston, Massachusetts, U.S.A}, booktitle = {Intermetallic-based alloys - science, technology and applications, symposium held November 25-30, Boston, Massachusetts, U.S.A}, publisher = {Cambridge Univ. Press}, address = {Cambridge}, doi = {10.1557/opl.2012.1750}, pages = {215 -- 220}, language = {en} } @misc{BoehmKueckenAhrensetal., author = {B{\"o}hm, Uwe and K{\"u}cken, Martin and Ahrens, Wilfried and Block, Alexander and Hauffe, Detlef and Keuler, Klaus and Rockel, Burkhardt and Will, Andreas}, title = {The Climate Version of LM: Brief Description and Long-Term Applications}, series = {COSMO Newsletter}, journal = {COSMO Newsletter}, number = {6}, pages = {225 -- 235}, language = {en} } @misc{SchoderArmbrusterMartin, author = {Schoder, Melanie and Armbruster, Udo and Martin, Andreas}, title = {Heterogen katalysierte Hydrierung von Kohlendioxid zu Methan unter erh{\"o}hten Dr{\"u}cken}, series = {Chemie Ingenieur Technik}, volume = {85}, journal = {Chemie Ingenieur Technik}, number = {3}, issn = {1522-2640}, pages = {344 -- 352}, language = {de} } @misc{LangeArmbrusterMartin, author = {Lange, Felix and Armbruster, Udo and Martin, Andreas}, title = {Heterogeneously-Catalyzed Hydrogenation of Carbon Dioxide to Methane using RuNi Bimetallic Catalysts}, series = {Energy Technology}, volume = {3}, journal = {Energy Technology}, number = {1}, issn = {2194-4296}, doi = {10.1002/ente.201402113}, pages = {55 -- 62}, language = {en} } @incollection{KleefeldBreussWelketal., author = {Kleefeld, Andreas and Breuß, Michael and Welk, Martin and Burgeth, Bernhard}, title = {Adaptive Filters for Color Images: Median Filtering and Its Extensions}, series = {Computational Color Imaging}, booktitle = {Computational Color Imaging}, editor = {Tr{\´e}meau, Alain and Schettini, Raimondo and Tominaga, Shoji}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-319-15978-2}, doi = {10.1007/978-3-319-15979-9_15}, pages = {149 -- 158}, abstract = {In this paper we are concerned with robust structure-preserving denoising filters for color images. We build on a recently proposed transformation from the RGB color space to the space of symmetric 2×2 matrices that has already been used to transfer morphological dilation and erosion concepts from matrix-valued data to color images. We investigate the applicability of this framework to the construction of color-valued median filters. Additionally, we introduce spatial adaptivity into our approach by morphological amoebas that offer excellent capabilities for structure-preserving filtering. Furthermore, we define color-valued amoeba M-smoothers as a generalization of the median-based concepts. Our experiments confirm that all these methods work well with color images. They demonstrate the potential of our approach to define color processing tools based on matrix field techniques.}, language = {en} } @incollection{WelkKleefeldBreuss, author = {Welk, Martin and Kleefeld, Andreas and Breuß, Michael}, title = {Non-adaptive and Amoeba Quantile Filters for Colour Images}, series = {Mathematical Morphology and Its Applications to Signal and Image Processing}, booktitle = {Mathematical Morphology and Its Applications to Signal and Image Processing}, editor = {Benediktsson, J{\´o}n Atli and Chanussot, Jocelyn and Najman, Laurent and Talbot, Hugues}, publisher = {Springer International Publishing}, address = {Berlin}, isbn = {978-3-319-18719-8}, doi = {10.1007/978-3-319-18720-4_34}, pages = {398 -- 409}, abstract = {Quantile filters, or rank-order filters, are local image filters which assign quantiles of intensities of the input image within neighbourhoods as output image values. Combining a multivariate quantile definition developed in matrix-valued morphology with a recently introduced mapping between the RGB colour space and the space of symmetric 2×2 matrices, we state a class of colour image quantile filters, along with a class of morphological gradient filters derived from these. Using amoeba structuring elements, we devise image-adaptive versions of both filter classes. Experiments demonstrate the favourable properties of the filters.}, language = {en} } @misc{SchlummerArendsMaeureretal., author = {Schlummer, Martin and Arends, Dagmar and M{\"a}urer, Andreas and Markowski, Jens and Wagenknecht, Udo}, title = {Characterisation and materials flow management for waste electrical and electronic equipment plastics from German dismantling centres}, series = {Waste Management \& Research}, volume = {33}, journal = {Waste Management \& Research}, number = {9}, issn = {1096-3669}, doi = {10.1177/0734242x15588585}, pages = {775 -- 784}, abstract = {Waste electrical and electronic equipment is a complex waste stream and treatment options that work for one waste category or product may not be appropriate for others. A comprehensive case study has been performed for plastic-rich fractions that are treated in German dismantling centres. Plastics from TVs, monitors and printers and small household appliances have been characterised extensively. Based on the characterisation results, state-of-the-art treatment technologies have been combined to design an optimised recycling and upgrade process for each input fraction. High-impact polystyrene from TV casings that complies with the European directive on the restriction of hazardous substances (RoHS) was produced by applying continuous density separation with yields of about 60\%. Valuable acrylonitrile butadiene styrene/ polycarbonate can be extracted from monitor and printer casings by near- infrared-based sorting. Polyolefins and/or a halogen-free fraction of mixed styrenics can be sorted out by density separation from monitors and printers and small household appliances. Emerging separation technologies are discussed to improve recycling results.}, language = {en} } @incollection{SchneiderSchwerdtKruipetal., author = {Schneider, Peter Iren{\"a}us and Schwerdt, N. and Kruip, M. and Dally, Ortwin and Maischberger, Martin and Scholl, Andreas}, title = {Die Aufgabe der Faustinathermen als Terminus post quem f{\"u}r den Bau der byzantinischen Stadtmauer}, series = {Arch{\"a}ologischer Anzeiger : 2. Halbband 2013}, booktitle = {Arch{\"a}ologischer Anzeiger : 2. Halbband 2013}, number = {2}, publisher = {Wasmuth}, address = {T{\"u}bingen [u.a.]}, isbn = {978-3-8030-2351-3}, pages = {186 -- 189}, language = {de} } @misc{KrondakBroncovaAnikinetal., author = {Krondak, Martin and Broncov{\´a}, Gabriela and Anikin, Sergey and Merz, Andreas and Mirsky, Vladimir M.}, title = {Chemosensitive properties of poly-4,4'-dialkoxy2,2'-bipyrroles}, series = {Journal of Solid State Electrochemistry}, volume = {10}, journal = {Journal of Solid State Electrochemistry}, number = {3}, issn = {1432-8488}, doi = {10.1007/s10008-005-0069-8}, pages = {185 -- 191}, abstract = {Chemosensitive properties of 4,4′-dimethoxy-2,2′-bipyrrole and 4,4′-dibuthoxy-2,2′-bipyrrole were investigated. These new conductive polymers were polymerized by cyclic voltammetry on the platinum and gold interdigitated electrodes designed for 2- and 4-point measurement of lateral conductivity. Thus, obtained polymers demonstrated high sensitivity to HCl in the parts per million concentration range. Kinetics of the gaseous HCl influence on the ratios of conductivities measured by 2- and 4-point techniques was analyzed. Some response of the polymers conductance towards NH3, NO and oxygen was also observed, but with much lower sensitivity than towards HCl. In aqueous solutions, the polymer conductivity was pH dependent; in comparison with 4,4′-dibuthoxy-2,2′-bipyrrole, the conductivity range of the methoxy derivative was shifted to acidic range for about two pH units. A possibility to use the pH dependence for the development of enzymatic biosensors with pH transducing was demonstrated.}, language = {en} } @inproceedings{SeeligBurchardtKrebsetal., author = {Seelig, Torsten and Burchardt, Martin and Krebs, Andreas and Harlander, Uwe and Egbers, Christoph}, title = {PIV measurements in an axially stratified Taylor-Couette experiment}, series = {Book of abstracts, School ISTROF 2016, Instabilities and Turbulence in Strato-Rotational Flows, July 11-13th, 2016, Le Havre}, booktitle = {Book of abstracts, School ISTROF 2016, Instabilities and Turbulence in Strato-Rotational Flows, July 11-13th, 2016, Le Havre}, language = {en} } @misc{SchnellenbachBorchardDoeringetal., author = {Schnellenbach, Jan and Borchard, Michael and Doering, Detmar and Freytag, Andreas and Habermann, Gerd and Hagen, Albrecht von der and Hasse, Rolf and Horn, Karen and Kolev, Stefan and K{\"o}ster, Thomas and Roth, Steffen J. and Starbatty, Joachim and Wilde, Martin and Wohlgemuth, Michael}, title = {Wirtschaftsverfassung statt Wirtschaftsregierung, Frankfurter Aufruf f{\"u}r eine ordnungspolitische Weichenstellung in Europa}, series = {Frankfurter Allgemeine Zeitung}, journal = {Frankfurter Allgemeine Zeitung}, number = {22.06.2012}, language = {de} } @misc{WelkKleefeldBreuss, author = {Welk, Martin and Kleefeld, Andreas and Breuß, Michael}, title = {Quantile Filtering of Colour Images via Symmetric Matrices}, series = {Mathematical Morphology - Theory and Applications}, volume = {1}, journal = {Mathematical Morphology - Theory and Applications}, number = {1}, issn = {2353-3390}, doi = {10.1515/mathm-2016-0008}, pages = {136 -- 174}, abstract = {Quantile filters, or rank-order filters, are local image filters which assign quantiles of intensities of the input image within neighbourhoods as output image values. Combining a multivariate quantile definition developed in matrix-valued morphology with a recently introduced mapping between the RGB colour space and the space of symmetric 2 × 2 matrices, we state a class of colour image quantile filters, along with a class of morphological gradient filters derived from these.We consider variants of these filters based on three matrix norms - the nuclear, Frobenius, and spectral norm - and study their differences. We investigate the properties of the quantile and gradient filters and their links to dilation and erosion operators. Using amoeba structuring elements,we devise image-adaptive versions of our quantile and gradient filters. Experiments are presented to demonstrate the favourable properties of the filters, and compare them to existing approaches in colour morphology.}, language = {de} } @misc{TrautmannSanftlKoelpinetal., author = {Trautmann, Martin and Sanftl, Benedikt and K{\"o}lpin, Alexander and Heckel, Thomas and Frey, Lothar and Ditze, Stefan and Endruschat, Achim and Joffe, Christopher and Rosskopf, Andreas and Schriefer, Thomas}, title = {System zur drahtlosen {\"U}bertragung von Energie und Daten}, language = {de} } @misc{BambachSizovaSviridovetal., author = {Bambach, Markus and Sizova, Irina and Sviridov, Alexander and Stendal, Johan Andreas and G{\"u}nther, Martin}, title = {Batch Processing in Preassembled Die Sets - A New Process Design for Isothermal Forging of Titanium Aluminides}, series = {Journal of Manufacturing and Materials Processing}, volume = {2}, journal = {Journal of Manufacturing and Materials Processing}, number = {1}, issn = {2504-4494}, doi = {doi:10.3390/jmmp2010001}, pages = {14}, language = {en} } @misc{KammererSokolowskiHackletal., author = {Kammerer, Sarah and Sokolowski, Armin Andreas and Hackl, Hubert and Platzer, Dieter and Jahn, Stephan Wenzel and El-Heliebi, Amin and Schwarzenbacher, Daniela and Stiegelbauer, Verena and Pichler, Martin and Rezania, Simin and Fiegl, Heidelinde and Peintinger, Florentia and Regitnig, Peter and H{\"o}fler, Gerald and Schreibmayer, Wolfgang and Bauernhofer, Thomas}, title = {KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients}, series = {OncoTarget : open access impact journal}, volume = {7}, journal = {OncoTarget : open access impact journal}, number = {51}, doi = {10.18632/oncotarget.13224}, pages = {84705 -- 84717}, abstract = {Numerous studies showed abnormal expression of ion channels in different cancer types. Amongst these, the potassium channel gene KCNJ3 (encoding for GIRK1 proteins) has been reported to be upregulated in tumors of patients with breast cancer and to correlate with positive lymph node status. We aimed to study KCNJ3 levels in different breast cancer subtypes using gene expression data from the TCGA, to validate our findings using RNA in situ hybridization in a validation cohort (GEO ID GSE17705), and to study the prognostic value of KCNJ3using survival analysis. In a total of > 1000 breast cancer patients of two independent data sets we showed a) that KCNJ3 expression is upregulated in tumor tissue compared to corresponding normal tissue (p < 0.001), b) that KCNJ3 expression is associated with estrogen receptor (ER) positive tumors (p < 0.001), but that KCNJ3 expression is variable within this group, and c) that ER positive patients with high KCNJ3 levels have worse overall (p < 0.05) and disease free survival probabilities (p < 0.01), whereby KCNJ3 is an independent prognostic factor (p <0.05). In conclusion, our data suggest that patients with ER positive breast cancer might be stratified into high risk and low risk groups based on the KCNJ3 levels in the tumor.}, language = {en} } @inproceedings{ZaussingerEgbersDriebeetal., author = {Zaussinger, Florian and Egbers, Christoph and Driebe, Thomas and Heintzmann, Pascal and Canfield, Peter and Meier, Martin and Travnikov, Vadim and Froitzheim, Andreas and Haun, Peter}, title = {ATMOFLOW - Simulating atmosphere flows on the international space station. Part II: Experiments and numerical simulations}, series = {69th International Astronautical Congress, 1 - 5 October 2018, Bremen, Germany}, booktitle = {69th International Astronautical Congress, 1 - 5 October 2018, Bremen, Germany}, pages = {1}, language = {en} } @inproceedings{PanchenkoLanzeZinnenetal., author = {Panchenko, Andriy and Lanze, Fabian and Zinnen, Andreas and Henze, Martin and Pennekamp, Jan and Engel, Thomas and Wehrle, Klaus}, title = {Website Fingerprinting at Internet Scale}, series = {Proceedings of the 23rd Internet Society (ISOC) Network and Distributed System Security Symposium (NDSS 2016), San Diego, USA, February 2016}, booktitle = {Proceedings of the 23rd Internet Society (ISOC) Network and Distributed System Security Symposium (NDSS 2016), San Diego, USA, February 2016}, publisher = {Internet Society}, address = {Reston, VA}, isbn = {1-891562-41-X}, pages = {15}, language = {en} } @misc{BochAllanBirkhoferetal., author = {Boch, Steffen and Allan, Eric and Birkhofer, Klaus and Bossdorf, Oliver and Bl{\"u}thgen, Nico and Christ-Breulmann, Sabina and Diek{\"o}tter, Tim and Dormann, Carsten F. and Gossner, Martin M. and Hallmann, Christine and Hemp, Andreas and H{\"o}lzel, Norbert and Jung, Kirsten and Klaus, Valentin H. and Klein, Alexandra M. and Kleinebecker, Till and Lange, Markus and M{\"u}ller, J{\"o}rg and Nacke, Heiko and Prati, Daniel and Renner, Swen C. and Rothenw{\"o}hrer, Christoph and Schall, Peter and Schulze, Ernst-Detlef and Socher, Stephanie A. and Tscharntke, Teja and T{\"u}rke, Manfred and Weiner, Christiane N. and Weisser, Wolfgang W. and Westphal, Catrin and Wolters, Volkmar and Wubet, Tesfaye and Fischer, Markus}, title = {Extensive und j{\"a}hrlich wechselnde Nutzungsintensit{\"a}t f{\"o}rdert den Artenreichtum im Gr{\"u}nland}, series = {ANLIEGEN NATUR}, volume = {38}, journal = {ANLIEGEN NATUR}, number = {1}, issn = {1864-0729}, pages = {86 -- 95}, language = {de} } @misc{HauschildtStarkSchelletal., author = {Hauschildt, Katja and Stark, Andreas and Schell, Norbert and M{\"u}ller, Martin and Pyczak, Florian}, title = {The transient liquid phase bonding process of a γ-TiAl alloy with brazing solders containing Fe or Ni}, series = {Intermetallics}, volume = {106}, journal = {Intermetallics}, issn = {0966-9795}, pages = {48 -- 58}, language = {en} } @misc{ZaussingerCanfieldFroitzheimetal., author = {Zaussinger, Florian and Canfield, Peter and Froitzheim, Andreas and Travnikov, Vadim and Haun, Peter and Meier, Martin and Meyer, Antoine and Heintzmann, Pascal and Driebe, Thomas and Egbers, Christoph}, title = {AtmoFlow - Investigation of Atmospheric-Like Fluid Flows Under Microgravity Conditions}, series = {Microgravity Science and Technology : An International Journal for Microgravity and Space Exploration Related Research}, journal = {Microgravity Science and Technology : An International Journal for Microgravity and Space Exploration Related Research}, publisher = {Springer}, issn = {0938-0108}, doi = {10.1007/s12217-019-09717-7}, pages = {1 -- 19}, language = {en} } @misc{FuegenschuhHomfeldHucketal., author = {F{\"u}genschuh, Armin and Homfeld, Henning and Huck, Andreas and Martin, Alexander and Yuan, Zhi}, title = {Scheduling Locomotives and Car Transfers in Freight Transport}, series = {Transportation Science}, volume = {42}, journal = {Transportation Science}, number = {4}, issn = {1526-5447}, doi = {10.1287/trsc.1080.0248}, pages = {478 -- 491}, language = {en} } @misc{KuebartStabler, author = {Kuebart, Andreas and Stabler, Martin}, title = {Infectious Diseases as Socio-Spatial Processes: The COVID-19 Outbreak In Germany}, series = {Tijdschrift voor economische en sociale geografie = Journal of economic and social geography}, volume = {111}, journal = {Tijdschrift voor economische en sociale geografie = Journal of economic and social geography}, number = {3}, issn = {1467-9663}, doi = {10.1111/tesg.12429}, pages = {482 -- 496}, abstract = {This paper argues that outbreaks of infectious diseases should be understood as socio-spatial processes with complex geographies. Considering the different dimensions of space through which an outbreak unfolds, facilitates analysing spatial diffusion of infectious disease in contemporary societies. We attempt to highlight four relevant dimensions of space by applying the TPSN framework to the case of the recent COVID-19 outbreak in Germany. By identifying key processes of disease diffusion in space, we can explain the spatial patterns of the COVID-19 outbreak in Germany, which did not feature the well-known patterns of spatially contagious as in or hierarchical diffusion. In contrast, we find superspreading events and especially relocation diffusion based on existing networks, on which the pathogen travelled like a blind passenger, to be more relevant. For us, these findings prove the value of combining relational thinking with geographic analysis for understanding epidemic outbreaks in contemporary societies.}, language = {en} } @incollection{KuebartStabler, author = {Kuebart, Andreas and Stabler, Martin}, title = {Infektionsnetzwerke und Infektionsorte-Super-spreading-Ereignisse in der Epidemie}, series = {Corona-Netzwerke-Gesellschaft im Zeichen des Virus}, booktitle = {Corona-Netzwerke-Gesellschaft im Zeichen des Virus}, editor = {Stegbauer, Christian and Clemens, Iris}, edition = {1. Auflage}, publisher = {Springer}, address = {Wiesbaden}, isbn = {978-3-658-31394-4}, doi = {10.1007/978-3-658-31394-4_4}, pages = {35 -- 43}, abstract = {F{\"u}r die Analyse von Ausbr{\"u}chen von Infektionskrankheiten wie der neuartigen Coronaviruskrankheit COVID-19, die sich {\"u}ber Tr{\"o}pfchen, Aerosole oder Kontaktinfektion ausbreiten, bietet ein netzwerktheoretischer Ansatz einen besonderen Mehrwert, da eine Ansteckung von einer Person auf die andere notwendigerweise einen direkten Kontakt unter Kopr{\"a}senz impliziert und der Ausbruch im gr{\"o}ßeren Maßstab somit ein Netzwerkmuster aufweist. Neben dem f{\"u}r ein Infektionsgeschehen notwendigen Kontakt zwischen einem infekti{\"o}sen und einem infizierbaren Individuum gibt es mit dem Ort des Infektionsprozesses allerdings noch eine weitere Variable, die die Rahmenbedingungen bestimmt und von erheblicher Bedeutung sein kann.}, language = {de} } @misc{KuebartStabler, author = {Kuebart, Andreas and Stabler, Martin}, title = {Risikoprozesse statt Risikogebiete : Raumdimensionen der COVID-19-Pandemie in Deutschland}, series = {Informationen zur Raumentwicklung}, volume = {48}, journal = {Informationen zur Raumentwicklung}, number = {2}, pages = {40 -- 49}, language = {de} } @techreport{BoehmKueckenAhrensetal., author = {B{\"o}hm, Uwe and K{\"u}cken, Martin and Ahrens, Wilfried and Block, Alexander and Hauffe, Detlef and Keuler, Klaus and Rockel, Burkhardt and Will, Andreas}, title = {CLM - The Climate Version of LM: Brief Description and Long-Term Applications}, publisher = {COSMO Newsletter}, address = {Offenbach, Germany}, pages = {11}, language = {en} } @misc{MartinBraunMicheletal., author = {Martin, Titus and Braun, Alexander and Michel, Sven and Wendler, Johannes and Nocke, Andreas and Cherif, Chokri and Ibarlucea, Bergoi and Cuniberti, Gianaurelio}, title = {Development of textile-based and planar sensors for continuous non-invasive real-time recording of the lactate value curve for diagnostics according to clinical requirements}, publisher = {ADD International Textile Conference 2021}, pages = {1}, abstract = {We hereby present the findings for a new technology to produce portable, flexible, long- term stable and high-resolution sensors and measuring systems for individual lactate value recording in body sweat for regenerative and sports. A main goal of this study has been the identification of application sites according to body sweat quality and quantity, as well as easy accessibility and handling of the measurement site. For the continuous recording of the lactate value curve with integrated temperature compensation, new types of multifunctional sensor constructions and evaluation algorithms have been developed that can detect and evaluate these parameters precisely and interference-free in real time in body sweat in order to establish a diagnostic correlation with the clinical, therapeutic and sports medicine performance- oriented application scenarios. For this purpose, suitable planar sensor principles have been investigated and a planar sensor was developed. A textile-based sensor suitable for long-term use (several hours to several days of use) has been developed as a braided construction. In particular, a functionalized chitosan layer with a sensitive enzyme and several required electrodes wires have been purposefully used. Due to a high selectivity, i.e. clear signal interpretation even in the presence of other substances in body sweat, enzymatic measuring systems in an amperometric measure- ment design were primarily investigated. The preferred solution of the developed planar sensor is to be used as a reference sensor for calibration and, together with the preferred solution of the textile sensor, is to be integrated into the demonstrators. From the intended project results, an immediate direct benefit can be derived for SMEs in the textile manufacturing, finishing and medical products sectors and for the measurement and sensor technology sector.}, language = {en} } @misc{StrobelAlvaradoChavarinRichteretal., author = {Strobel, Carsten and Alvarado Chavarin, Carlos and Richter, Karola and Knaut, Martin and Reif, Johanna and Völkel, Sandra and Jahn, Andreas and Albert, Matthias and Wenger, Christian and Kirchner, Robert and Bartha, Johann Wolfgang and Mikolajick, Thomas}, title = {Novel Graphene Adjustable-Barrier Transistor with Ultra-High Current Gain}, series = {ACS Applied Materials \& Interfaces}, volume = {14}, journal = {ACS Applied Materials \& Interfaces}, number = {34}, issn = {1944-8244}, doi = {10.1021/acsami.2c10634}, pages = {39249 -- 39254}, abstract = {A graphene-based three terminal barristor device was proposed to overcome the low on/off ratios and insufficient current saturation of conventional graphene field effect transistors. In this study, we fabricated and analyzed a novel graphene-based transistor, which resembles the structure of the barristor but uses a different operating condition. This new device, termed graphene adjustable-barriers transistor (GABT), utilizes a semiconductor-based gate rather than a metal-insulator gate structure to modulate the device currents. The key feature of the device is the two graphene-semiconductor Schottky barriers with different heights that are controlled simultaneously by the gate voltage. Due to the asymmetry of the barriers, the drain current exceeds the gate current by several orders of magnitude. Thus, the GABT can be considered an amplifier with an alterable current gain. In this work, a silicon-graphene-germanium GABT with an ultra-high current gain (ID/IG up to 8 × 106) was fabricated, and the device functionality was demonstrated. Additionally, a capacitance model is applied to predict the theoretical device performance resulting in an on-off ratio above 106, a swing of 87 mV/dec, and a drivecurrent of about 1 × 106 A/cm2.}, language = {en} } @incollection{DallyMaischbergerSchneideretal., author = {Dally, Ortwin and Maischberger, Martin and Schneider, Peter Iren{\"a}us and Scholl, Andreas}, title = {The Town Center of Miletus from Roman Imperial Times to Late Antiquity}, series = {Archaeology and the Cities of Asia Minor in Late Antiquity}, booktitle = {Archaeology and the Cities of Asia Minor in Late Antiquity}, publisher = {Kelsey Museum of Archaeology}, address = {Ann Arbor}, isbn = {978-0-974-18735-8}, pages = {81 -- 101}, language = {de} } @misc{PennekampHenzeZinnenetal., author = {Pennekamp, Jan and Henze, Martin and Zinnen, Andreas and Lanze, Fabian and Wehrle, Klaus and Panchenko, Andriy}, title = {CUMUL \& Co: High-Impact Artifacts for Website Fingerprinting Research}, series = {38th Annual Computer Security Applications Conference (ACSAC 2022), Austin, Texas, USA, December 5-9, 2022.}, journal = {38th Annual Computer Security Applications Conference (ACSAC 2022), Austin, Texas, USA, December 5-9, 2022.}, pages = {6}, abstract = {Anonymous communication on the Internet is about hiding the relationship between communicating parties. At NDSS '16, we presented a new website fingerprinting approach, CUMUL, that utilizes novel features and a simple yet powerful algorithm to attack anonymization networks such as Tor. Based on pattern observation of data flows, this attack aims at identifying the content of encrypted and anonymized connections. Apart from the feature generation and the used classifier, we also provided a large dataset to the research community to study the attack at Internet scale. In this paper, we emphasize the impact of our artifacts by analyzing publications referring to our work with respect to the dataset, feature extraction method, and source code of the implementation. Based on this data, we draw conclusions about the impact of our artifacts on the research field and discuss their influence on related cybersecurity topics. Overall, from 393 unique citations, we discover more than 130 academic references that utilize our artifacts, 61 among them are highly influential (according to SemanticScholar), and at least 43 are from top-ranked security venues. This data underlines the significant relevance and impact of our work as well as of our artifacts in the community and beyond.}, language = {en} } @misc{VillasmuntaSteglichVillringeretal., author = {Villasmunta, Francesco and Steglich, Patrick and Villringer, Claus and Schrader, Sigurd and Schenk, Harald and Mai, Andreas and Regehly, Martin}, title = {Design, fabrication, and characterization of integrated optical through-silicon waveguides for 3D photonic interconnections}, series = {Optical Interconnects XXIV}, journal = {Optical Interconnects XXIV}, editor = {Schr{\"o}der, Henning and Chen, Ray T.}, publisher = {SPIE}, doi = {10.1117/12.3003146}, pages = {12}, language = {en} } @misc{HerrmannFerchauLeeetal., author = {Herrmann, Andreas and Ferchau, Erik and Lee, Roh Pin and Simon, Marc-Ren{\´e} and Wasner, Jenny and Gr{\"a}bner, Martin}, title = {Biogas as a renewable carbon carrier for the chemical industry}, series = {The 12th International Freiberg Conference on Circular Carbon Technologies will take place from 23-26 September 2024 in Shanghai, China}, journal = {The 12th International Freiberg Conference on Circular Carbon Technologies will take place from 23-26 September 2024 in Shanghai, China}, issn = {2363-8702}, pages = {1}, language = {en} } @misc{KuebartStabler, author = {Kuebart, Andreas and Stabler, Martin}, title = {Waves in time, but not in space-An analysis of pandemic severity of COVID-19 in Germany based on spatio-temporal clustering}, series = {medRxiv}, journal = {medRxiv}, doi = {10.1101/2023.01.27.23285105}, pages = {1 -- 20}, language = {en} } @misc{KuebartStabler, author = {Kuebart, Andreas and Stabler, Martin}, title = {Waves in time, but not in space - an analysis of pandemic severity of COVID-19 in Germany}, series = {Spatial and spatio-temporal epidemiology}, volume = {47}, journal = {Spatial and spatio-temporal epidemiology}, issn = {1877-5845}, doi = {10.1016/j.sste.2023.100605}, pages = {1 -- 9}, abstract = {While pandemic waves are often studied on the national scale, they typically are not distributed evenly within countries. This study presents a novel approach to analyzing the spatial-temporal dynamics of the COVID-19 pandemic in Germany. By using a composite indicator of pandemic severity and subdividing the pandemic into fifteen phases, we were able to identify similar trajectories of pandemic severity among all German counties through hierarchical clustering. Our results show that the hotspots and cold spots of the first four waves were relatively stationary in space. This highlights the importance of examining pandemic waves on a regional scale to gain a more comprehensive understanding of their dynamics. By combining spatial autocorrelation and spatial-temporal clustering of time series, we were able to identify important patterns of regional anomalies, which can help target more effective public health interventions on a regional scale.}, language = {en} } @misc{StrobelAlvaradoChavarinVoelkeletal., author = {Strobel, Carsten and Alvarado Chavarin, Carlos and V{\"o}lkel, Sandra and Jahn, Andreas and Hiess, Andre and Knaut, Martin and Albert, Matthias and Wenger, Christian and Steinke, Olaff and Stephan, Ulf and R{\"o}hlecke, S{\"o}ren and Mikolajick, Thomas}, title = {Enhanced Electrical Properties of Optimized Vertical Graphene-Base Hot Electron Transistors}, series = {ACS Applied Electronic Materials}, volume = {5}, journal = {ACS Applied Electronic Materials}, number = {3}, issn = {2637-6113}, doi = {10.1021/acsaelm.2c01725}, pages = {1670 -- 1675}, abstract = {The arrival of high-mobility two-dimensional materials like graphene leads to the renaissance of former vertical semiconductor-metal-semiconductor (SMS) hot electron transistors. Because of the monolayer thickness of graphene, improved SMS transistors with a semimetallic graphene-base electrode are now feasible for high-frequency applications. In this study we report about a device that consists of amorphous silicon, graphene, and crystalline silicon. For the first time, this device is fabricated by a four-mask lithography process which leads to significant improvements in the device performance. A strongly increased common-emitter current gain of 2\% could be achieved while the on-off ratio improved to 1.6 × 105, which is already higher than predicted theoretically. This could be mainly attributed to better interface characteristics and decreased lateral dimensions of the devices. A cutoff frequency of approximately 26 MHz could be forecasted based on the DC measurements of the device.}, language = {en} } @misc{StablerKuebart, author = {Stabler, Martin and Kuebart, Andreas}, title = {Tempo-spatial dynamics of COVID-19 in Germany: A phase model based on a pandemic severity indicator}, series = {medRxiv}, journal = {medRxiv}, doi = {10.1101/2023.02.17.23286084}, language = {en} } @misc{KahraBreussKleefeldetal., author = {Kahra, Marvin and Breuß, Michael and Kleefeld, Andreas and Welk, Martin}, title = {An Approach to Colour Morphological Supremum Formation using the LogSumExp Approximation}, series = {arXiv}, journal = {arXiv}, doi = {10.48550/arXiv.2312.13792}, pages = {1 -- 12}, abstract = {Mathematical morphology is a part of image processing that has proven to be fruitful for numerous applications. Two main operations in mathematical morphology are dilation and erosion. These are based on the construction of a supremum or infimum with respect to an order over the tonal range in a certain section of the image. The tonal ordering can easily be realised in grey-scale morphology, and some morphological methods have been proposed for colour morphology. However, all of these have certain limitations. In this paper we present a novel approach to colour morphology extending upon previous work in the field based on the Loewner order. We propose to consider an approximation of the supremum by means of a log-sum exponentiation introduced by Maslov. We apply this to the embedding of an RGB image in a field of symmetric 2×2 matrices. In this way we obtain nearly isotropic matrices representing colours and the structural advantage of transitivity. In numerical experiments we highlight some remarkable properties of the proposed approach.}, language = {en} } @misc{KahraBreussKleefeldetal., author = {Kahra, Marvin and Breuß, Michael and Kleefeld, Andreas and Welk, Martin}, title = {An Approach to Colour Morphological Supremum Formation Using the LogSumExp Approximation}, series = {Lecture Notes in Computer Science}, volume = {14605}, journal = {Lecture Notes in Computer Science}, publisher = {Springer Nature Switzerland}, address = {Cham}, isbn = {9783031577925}, issn = {0302-9743}, doi = {10.1007/978-3-031-57793-2_25}, pages = {325 -- 337}, abstract = {Mathematical morphology is a part of image processing that has proven to be fruitful for numerous applications. Two main operations in mathematical morphology are dilation and erosion. These are based on the construction of a supremum or infimum with respect to an order over the tonal range in a certain section of the image. The tonal ordering can easily be realised in grey-scale morphology, and some morphological methods have been proposed for colour morphology. However, all of these have certain limitations. In this paper we present a novel approach to colour morphology extending upon previous work in the field based on the Loewner order. We propose to consider an approximation of the supremum by means of a log-sum exponentiation introduced by Maslov. We apply this to the embedding of an RGB image in a field of symmetric matrices. In this way we obtain nearly isotropic matrices representing colours and the structural advantage of transitivity. In numerical experiments we highlight some remarkable properties of the proposed approach.}, language = {en} } @misc{FuenningPaulManganellietal., author = {F{\"u}nning, Tabea and Paul, Martin and Manganelli, Costanza Lucia and Wenger, Christian and Mai, Andreas and Steglich, Patrick}, title = {Comparative simulation analysis of photonic ultrasound sensors based on silicon waveguides}, series = {Scientific reports}, volume = {15}, journal = {Scientific reports}, number = {1}, publisher = {Springer Science and Business Media LLC}, address = {[London]}, issn = {2045-2322}, doi = {10.1038/s41598-025-01953-9}, pages = {1 -- 13}, abstract = {Pressure sensors based on photonic integrated circuits (PIC) offer the prospect of outstanding sensitivities, extreme miniaturization and have the potential for highly scalable production using CMOS compatible processing. PIC-based pressure sensors detect the change in optical properties, i.e. the intensity or phase of the optical carrier wave inside miniaturized waveguide structures. The detection of ultrasound is achieved by engineering the waveguide architecture such that a pressure causes a high change in the effective refractive index of the waveguide. A range of PIC-based pressure sensors have been reported, but a comparison of the sensitivity of the different approaches is not straightforward, since different pressure sensitive waveguide architectures as well as photonic layouts and measurement setups impact the performance. Additionally, the used sensitivity unit is not uniform throughout the different studies, further complicating a comparison. In this work, a detailed simulation study is carried out by finite element modeling of different pressure sensitive waveguide architectures for a consistent comparison. We analyze three different sensor architectures: (A) a free standing membrane located within a tiny air gap above the waveguide, (B) a waveguide located on top of a deflectable membrane as well as (C) a waveguide embedded inside a pressure-sensitive polymer cladding. The mechanical response of the structures and the resulting changes in mode propagation, i.e. the change of the effective refractive index, are analyzed. The waveguide sensitivities in RIU/MPa for different waveguide types (strip, slot) and polarization states (TE, TM) are compared. The results reveal inherent limitations of the different waveguide designs and create a basis for the selection of suitable designs for further ultrasound sensor development. Possibilities for enhancing waveguide sensitivity are identified and discussed. Additionally, we have shown that the studied approaches are extensible to SiN waveguides.}, language = {en} } @misc{KahraBreussKleefeldetal., author = {Kahra, Marvin and Breuß, Michael and Kleefeld, Andreas and Welk, Martin}, title = {Matrix-valued LogSumExp approximation for colour morphology}, series = {Journal of mathematical imaging and vision}, volume = {67}, journal = {Journal of mathematical imaging and vision}, number = {5}, publisher = {Springer US}, address = {New York}, issn = {0924-9907}, doi = {10.1007/s10851-025-01267-5}, abstract = {Mathematical morphology is a part of image processing that employs a moving window to modify pixel values through the application of specific operations. The supremum and infimum are pivotal concepts, yet defining them in a general sense for high-dimensional data such as colour is a challenging endeavour. As a result, a number of different approaches have been taken to try to find a solution, with certain compromises being made along the way. In this paper, we present an analysis of a novel approach that replaces the supremum within a morphological operation with the LogExp approximation of the maximum for matrix-valued colours. This approach has the advantage of extending the associativity of dilation from the one-dimensional to the higher-dimensional case. Furthermore, the minimality property is investigated and a relaxation specified to ensure that the approach is continuously dependent on the input data.}, language = {en} } @misc{VillasmuntaHeiseBreiteretal., author = {Villasmunta, Francesco and Heise, Patrick and Breiter, Manuela and Schrader, Sigurd and Schenk, Harald and Regehly, Martin and Mai, Andreas}, title = {Monolithically integrated optical through-silicon waveguides for 3D chip-to-chip photonic interconnects}, series = {IEEE journal of selected topics in quantum electronics}, volume = {32}, journal = {IEEE journal of selected topics in quantum electronics}, number = {2: 3-D Horizons in Photonics}, publisher = {Institute of Electrical and Electronics Engineers (IEEE)}, address = {New York, NY}, issn = {1077-260X}, doi = {10.1109/JSTQE.2025.3615001}, pages = {1 -- 15}, abstract = {The scaling limitations of electrical interconnects are driving the demand for efficient optical chip-to-chip links. We report the first monolithic integration of air-clad optical through-silicon waveguides in silicon, fabricated via Bosch and cryogenic deep reactive-ion etching. Rib, single-bridge, and double-bridge designs with 50 μm cores and up to 150 μm propagation lengths have been evaluated. Cryogenic-etched rib waveguides achieve the highest median transmission (66\%, -1.80 dB), compared to Bosch-etched ribs (62\%, -2.08 dB). Across all geometries, 3 dB alignment windows range from 9.3 μm to 49.2 μm, with Bosch-etched double-bridge waveguides providing the broadest tolerance. We show that geometric fidelity outweighs sidewall roughness for transmission and alignment in these large-core, multimode optical through-silicon waveguides. This technology provides a scalable, complementary metal-oxide semiconductor-compatible pathway toward 3D photonic interconnects.}, language = {en} } @misc{RachevaBasaloLouridoGurdaletal., author = {Racheva, Miroslava and Basalo Lourido, Javier and Gurdal, Enise Ece and Herbst, Martin and Bayar, Seyhmus and Radzik, Daniela and B{\"a}hr, Elen and Zwies, Constanze and Neffe, Axel T. and Pietzsch, Markus and Lendlein, Andreas and Wischke, Christian}, title = {Tyrosinase cross-linked PEG hydrogels with DAT and DATT as artificial substrates : design, structure, and functions}, series = {Biomacromolecules}, volume = {27}, journal = {Biomacromolecules}, number = {2}, publisher = {American Chemical Society (ACS)}, address = {Washington, DC}, issn = {1525-7797}, doi = {10.1021/acs.biomac.5c01929}, pages = {1317 -- 1336}, abstract = {Enzymes such as oxidases are sustainable tools for hydrogel synthesis, but complex competing reactions have limited the mechanistic understanding and biomedical applications of these materials. Guided by molecular docking and MM-GBSA calculations, we identified two artificial substrates, desaminotyrosine (DAT) and desaminotyrosyltyrosine (DATT), that were experimentally more efficiently converted by mushroom tyrosinase (mTyr) than the natural substrate tyrosine. These substrates were used to synthesize hydrogels from DAT/DATT-functionalized star-shaped oligoethylene glycol (sOEG). Model reactions elucidated the chemical nature and functionality of the hydrogel netpoints. Material properties were systematically investigated depending on sOEG molecular weight (5, 10, 20 kDa), substrate type, and mTyr concentration. Functional mesh sizes and controlled release functions were investigated with fluorescent dextrans (4-500 kDa) and heparin. Cell culture studies with L929 fibroblasts and THP-1 monocytes suggested inertness of the material. These findings provide fundamental insight into mTyr-catalyzed hydrogel formation and support further exploration for in situ hydrogel synthesis.}, language = {en} }