@misc{UmairMohsinAlietal., author = {Umair, Muhammad and Mohsin, Mashkoor and Ali, Qasim and Qamar, Muhammad U. and Raza, Shahbaz and Ali, Aamir and Guenther, Sebastian and Schierack, Peter}, title = {Prevalence and Genetic Relatedness of Extended Spectrum-ß-Lactamase-Producing Escherichia coli Among Humans, Cattle, and Poultry in Pakistan}, series = {Microbial drug resistance}, volume = {25}, journal = {Microbial drug resistance}, number = {9}, issn = {1931-8448}, doi = {10.1089/mdr.2018.0450}, pages = {1374 -- 1381}, language = {en} } @misc{KolendaBurdukiewiczWimonćetal., author = {Kolenda, Rafał and Burdukiewicz, Michał and Wimonć, Marcjanna and Aleksandrowicz, Adrianna and Ali, Aamir and Szabo, Istvan and Tedin, Karsten and Bartholdson, Scott J. and Pickhard, Derek and Schierack, Peter}, title = {Identification of Natural Mutations Responsible for Altered Infection Phenotypes of Salmonella enterica Clinical Isolates by Using Cell Line Infection Screens}, series = {Applied and Environmental Microbiology}, volume = {87}, journal = {Applied and Environmental Microbiology}, number = {2}, issn = {1098-5336}, doi = {10.1128/AEM.02177-20}, language = {en} } @misc{AwanSchiebelBoehmetal., author = {Awan, Asad Bashir and Schiebel, Juliane and B{\"o}hm, Alexander and Nitschke, J{\"o}rg and Sarwar, Yasra and Schierack, Peter and Ali, Aamir}, title = {Association of biofilm formation and cytotoxic potential with multidrug resistance in clinical isolates of Pseudomonas aeruginosa}, series = {EXCLI journal}, volume = {18}, journal = {EXCLI journal}, issn = {1611-2156}, pages = {79 -- 90}, language = {en} } @misc{KhanSidorczukBeckeretal., author = {Khan, Muhammad Moman and Sidorczuk, Katarzyna and Becker, Juliane and Aleksandrowicz, Adrianna and Baraniewicz, Karolina and Ludwig, Christina and Ali, Aamir and Kingsley, Robert A. and Schierack, Peter and Kolenda, Rafał}, title = {Characterization of clumpy adhesion of Escherichia coli to human cells and associated factors influencing antibiotic sensitivity}, series = {Microbiology Spectrum}, journal = {Microbiology Spectrum}, issn = {2165-0497}, doi = {10.1128/spectrum.02606-23}, abstract = {Escherichia coli intestinal infection pathotypes are characterized by distinct adhesion patterns, including the recently described clumpy adhesion phenotype. Here, we identify and characterize the genetic factors contributing to the clumpy adhesion of E. coli strain 4972. In this strain, the transcriptome and proteome of adhered bacteria were found to be distinct from planktonic bacteria in the supernatant. A total of 622 genes in the transcriptome were differentially expressed in bacteria present in clumps relative to the planktonic bacteria. Seven genes targeted for disruption had variable distribution in different pathotypes and nonpathogenic E. coli, with the pilV and spnT genes being the least frequent or absent from most groups. Deletion (Δ) of five differentially expressed genes, flgH, ffp, pilV, spnT, and yggT, affected motility, adhesion, or antibiotic stress. ΔflgH exhibited 80\% decrease and ΔyggT depicted 184\% increase in adhesion, and upon complementation, adhesion was significantly reduced to 13\%. ΔflgH lost motility and was regenerated when complemented, whereas Δffp had significantly increased motility, and reintroduction of the same gene reduced it to the wild-type level. The clumps produced by Δffp and ΔspnT were more resistant and protected the bacteria, with ΔspnT showing the best clump formation in terms of ampicillin stress protection. ΔyggT had the lowest tolerance to gentamicin, where the antibiotic stress completely eliminated the bacteria. Overall, we were able to investigate the influence of clump formation on cell surface adhesion and antimicrobial tolerance, with the contribution of several factors crucial to clump formation on susceptibility to the selected antibiotics.}, language = {en} } @misc{MohsinRazaRoschanskietal., author = {Mohsin, Mashkoor and Raza, Shahbaz and Roschanski, Nicole and Guenther, Sebastian and Ali, Aamir and Schierack, Peter}, title = {Description of the First Escherichia coli Clinical Isolate Harboring the Colistin Resistance Gene mcr-1 from the Indian Subcontinent}, series = {Antimicrobial Agents and Chemotherapy}, volume = {61}, journal = {Antimicrobial Agents and Chemotherapy}, number = {1}, issn = {1098-6596}, doi = {10.1128/AAC.01945-16}, pages = {2}, language = {en} } @misc{OloweAdefioyeAjayeobaetal., author = {Olowe, Olugbenga Adekunle and Adefioye, Olusolabomi J. and Ajayeoba, T. A. and Schiebel, Juliane and Weinreich, J{\"o}rg and Ali, Aamir and Burdukiewicz, Michał and R{\"o}diger, Stefan and Schierack, Peter}, title = {Phylogenetic grouping and biofilm formation of Multidrug Resistant Escherichia coli Isolates from Humans, Animals and Food products in South-west Nigeria}, series = {Scientific African}, volume = {6}, journal = {Scientific African}, issn = {2468-2276}, doi = {10.1016/j.sciaf.2019.e00158}, pages = {11}, language = {en} } @misc{WajidAwanSaleemietal., author = {Wajid, M. and Awan, Asad Bashir and Saleemi, M. K. and Weinreich, J{\"o}rg and Schierack, Peter and Sarwar, Y. and Ali, Aamir}, title = {Multiple Drug Resistance and Virulence Profiling of Salmonella enterica Serovars Typhimurium and Enteritidis from Poultry Farms of Faisalabad, Pakistan}, series = {Microbial Drug Resistance}, volume = {25}, journal = {Microbial Drug Resistance}, number = {1}, issn = {1931-8448}, doi = {10.1089/mdr.2018.0121}, pages = {133 -- 142}, language = {en} } @misc{AkhtarGhauriParveenetal., author = {Akhtar, Nasrin and Ghauri, M. A. and Parveen, Sana and Farooq, M. and Ali, Aamir and Schierack, Peter}, title = {Comparative Analysis of Draft Genome Sequence of Rhodococcus sp. Eu-32 with Other Rhodococcus Species for Its Taxonomie Status and Sulfur Metabolism Potential}, series = {Current microbiology}, volume = {76}, journal = {Current microbiology}, number = {10}, issn = {1432-0991}, doi = {10.1007/s00284-019-01737-1}, pages = {1207 -- 1214}, language = {en} } @misc{KhanAliKolendaetal., author = {Khan, Muhammad Moman and Ali, Aamir and Kolenda, Rafał and Olowe, Olugbenga Adekunle and Weinreich, J{\"o}rg and Li, Ganwu and Schierack, Peter}, title = {The role of AJB35136 and fdtA genes in biofilm formation by avian pathogenic Escherichia coli}, series = {BMC Veterinary Research}, volume = {19}, journal = {BMC Veterinary Research}, issn = {1746-6148}, doi = {10.1186/s12917-023-03672-7}, language = {en} } @misc{BartlitzKolendaChilimoniuketal., author = {Bartlitz, Christin and Kolenda, Rafał and Chilimoniuk, Jarosław and Grzymajlo, Krzysztof and R{\"o}diger, Stefan and Bauerfeind, Rolf and Ali, Aamir and Tchesnokovag, Veronika and Roggenbuck, Dirk and Schierack, Peter}, title = {Adhesion of Enteropathogenic, Enterotoxigenic, and Commensal Escherichia coli to the Major Zymogen Granule Membrane Glyoprotein 2}, series = {Applied abd Environmental Microbiology}, volume = {88}, journal = {Applied abd Environmental Microbiology}, number = {5}, issn = {1098-5536}, doi = {10.1128/aem.02279-21}, language = {en} }