Resolving the apparent gap in complexity between simulated and measured kinetics of biomolecules
Please always quote using this URN: urn:nbn:de:0296-matheon-11029
Molecular simulations of biomolecules often reveal a complex picture of the their kinetics,
whereas kinetic experiments typically seem to indicate considerably simpler two- or three-state
kinetics. Markov state models (MSM) provide a tool to link between simulation and experi-
ment, and to resolve this apparent contradiction.
| Author: | Bettina Keller, Jan-Hendrik Prinz, Frank Noe |
|---|---|
| URN: | urn:nbn:de:0296-matheon-11029 |
| Referee: | Christof Schütte |
| Language: | English |
| Date of first Publication: | 18.05.2012 |
| Institute: | DFG Research Center Matheon |
| Freie Universität Berlin | |
| Project: | A19 Modeling and optimization of functional molecules |
| MSC-Classification: | 62M05 Markov processes: estimation |
| Preprint Number: | Matheon Preprint #958 |


